Basic Information

Insect: Drosophila mauritiana
Gene Symbol: -
Assembly: GCA_004382145.1
Location: NC:21538436-21572088[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.034 2.1 8.6 2.3 1 23 1403 1425 1403 1426 0.95

2 8 0.0045 0.27 11.4 0.1 1 23 1431 1454 1431 1454 0.98

3 8 0.03 1.8 8.8 5.4 1 23 1735 1758 1735 1758 0.94

4 8 0.00047 0.029 14.5 2.1 1 23 1766 1788 1766 1788 0.98

5 8 4.9e-05 0.003 17.6 0.2 1 23 1795 1818 1795 1818 0.97

6 8 1.8e-05 0.0011 18.9 1.4 1 23 1824 1846 1824 1846 0.97

7 8 3e-06 0.00018 21.4 2.1 1 23 1851 1873 1851 1873 0.99

8 8 0.00027 0.016 15.2 3.9 1 23 1878 1900 1878 1900 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.034	2.1	8.6	2.3	1	23	1403	1425	1403	1426	0.95
2	8	0.0045	0.27	11.4	0.1	1	23	1431	1454	1431	1454	0.98
3	8	0.03	1.8	8.8	5.4	1	23	1735	1758	1735	1758	0.94
4	8	0.00047	0.029	14.5	2.1	1	23	1766	1788	1766	1788	0.98
5	8	4.9e-05	0.003	17.6	0.2	1	23	1795	1818	1795	1818	0.97
6	8	1.8e-05	0.0011	18.9	1.4	1	23	1824	1846	1824	1846	0.97
7	8	3e-06	0.00018	21.4	2.1	1	23	1851	1873	1851	1873	0.99
8	8	0.00027	0.016	15.2	3.9	1	23	1878	1900	1878	1900	0.99

Sequence Information

Coding Sequence: ATGAGTGCCAACCGAAGAAGACGCAGTGCATCAGCTGCGAGTGCAATTGCAGCAGaaagagcaacagcagcagcagcagcagaagcgaTATCAACTGCACCCTCCAAAGAGCAACTTTCTCCACCGATTGCTGGTGGCAGTGCTTCAGCTGATGAGGATTTACTGGAAATGCCTCGCATTTGCCGATGCTGTTGCAAACGGGATTTGAAATTACTCGGCTTATTCGAGGCCAGCCAACCAACACTGGCCAACACAACAGTGGCATCAGCATCAGTGGCATCGAACAAATCATCGGGAACATTAGCAAAAACATGTGCGACAGAAGCAGAAACCGAAACTCCACAGACATTGTCCGCAAATCCAGTAAATCCCGGGACTAAAGCTACATCATCTCCATCAGAAGCAGCTACAACGTTGTCCGCATCCACACACCCCGCGTCCGCCTCCTTCTCAtccacctcctcctcgtccACATCCACGTCTCCCATGAGGCGTCGCACCACTAACACCACCGCTCCATCCGCTCCGCCCGCTCCACGTGGTCGTAGCAGCGATAATGCCGTCGACTACACCCTCAGCGGGGCCCACAGCAGCATGGACATTGTCCTCGAGGAGATGACCATTTGGATGCTCAATATAAATCGCGACGATGGACTGCCGCAAGAAATCTGCCGGCAGTGCATGGCCCAGTTTTTGATGGTGGCCAAGTTCCGGCGGAAATGTGTACGGATGCAGCAGCGCCTGCAGGACTTTGCCCAGGAGATATCCGACCGCCAGACGGCCAGACAAGCGAAGCGTCAGCAAAAAGTCCAAAAGAAGACACACGATAGCTGGCTGCAGTTGGAGCCAACCAGCCACGAGGAGCAGCAGCCCATACGTAAGCGCCGCATGGTATCCGAATCGGACGGAGAttcgacagcagcagcagcagcaacagcaacaactccAGCCAAACAGGTGCGAACGGAGTTCGAGAATTTGCCACCGCCCAAACCAAGTCCTCAACAGCACCGAGTGCGCAAGTATCGAACCCTCTCCATTGGCTGTGAAATGGAGCGTCCCGCCGCGTCCATCAACGCCAGCAGCATGCCCTGGAAGACGAAGGCTGCCCGCAAACAACTTTCGGAGAGTCGGGCGTCCAGTTGCTCGACGGCGGTCATGTCGCCCAATCGCCAacgcagcagcaccagcagcagtgAACACATGAGCGACTTGTCCGTCGGTCCATGCTGTGGCTTCGAAAGCGACAGCAGTCCGTCCTCTACCTCCAACTCGGCGCGGAGATCGGTGATACTCGTTAAGCAGCAGTCGCCGGAGAAGACATCGCCCATGTATGATTTAATGCCGCGCAGGGGACGGCGGCCCAGGAAAGCGCCGATATACATGCCGGCCAAAAGACAGAGGCGATCGCTGGTTAGGAAGGAGCCGCTGAACCGAAAGGCGGCCGCGCAGCCAGTCAACGAAGAGAACAAAAAGTCTGATCAAAAGGATATATATCCGAAGGAACCAAGGAAGGAAGGCCTTGGACCGTCCTGTGATGAGGCCATCGACAGCACTTCCGATGCGCCAATGGAAGTAGCCTCTAATGTGGTCCAAAAGAAGTGCGatgaaatcaatttaaatgaTTTGATGCTATGTAAAATGCAAAAGGACATCACATCAAATGGCTTGATAGACAGTCGCGACCAGTTAGGCGCCATGGAAATGGAGCCGGTTAACGAAATGATAGCGTCCAATGGTGTAGTGAAGGAACTACCCCAAGCTGAGATGCACGTCCTCAACGCTCAAAATTATGAGGAAACATCATCCGAAAAGCAAACATTAGAAGCCACCAGCGTTATAAAAGAATCGATTCAATCAGAACCAACTGCTGTTAGAACGGAAATCGAGTCAATTGGGAATGACATCAGGGCTGGTTCTGATCTAGTGCAGTCCGAGGAACTGACCTCATCCACAGAAACCAGCGAGTTGCAAAGGAAAACTGTTCAGCAGTTGGAAACTATGGGACAGCAGGAATCTTGTGCGACACTACAAACCATGAAGAATGAGGCATCCGTCCAGCTAACGGAAACTGCGGACGAATCAGACTCTGCTGACCAGAGGGAGATCATAGTGAGCATACCGCTGGAGGTTCTGGATGAGAATCTGCAGCGTCGTCTTTGCGTGGATCCGGAAACTGAGGCCGCCAATCGCCAGTCCGCTGATCCCAAGGAGTTCCCCCTGCGCCCCGATGACGTGAACAACAACGAAAACGATGAAAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCCGAACCAATAAAATTGAAGCAACACCGCCTGGGGGAACGGAATCAGATGACACGGACACGGAAGAGGTGCCGATAGTGCGATCTGGGCCAACGCCCATGGATTTCATGGCCGAGTTCGCCAAGCACTGTGCGAACGGAATTGAACAGCTCAAGGTCACTACACCGGCGCCATCACCGACTCCCTCGGATTTGGTGCCCCTCAACGATCTGGAGGCCAAGCAGAAACTGGAGGTAGAGATGAACGACGTGGAGACCACACTCAATGGCATCCTCAACGAGATGCAGGACCAGCACATGTACACACCAAACTGTGCCCACATTGATGAGTTCCTTACTCCAGCCGATTATGCCACACTGACTGAGCAGGAGTCGCCCGTTTCGTCGCCACCAAATCCTTTCGAGCAGAATTCTATTGCTGAACCGAAGGACGAGAAGCCCAATGCCACTGAGGATCCCTTTGATAATAGCAACTTTACCAATGAACTGATTGGTTTCCAAAACGATATTCCCTGCTTCGAGAACATTGAGACACCGGAGCAGGGACAAAACTTGCATTTAGAACTGACCCAGTTCTTAAGGGATCTGCAGCCGGCACAATCCGATCCGCCGGCAGAGGAGCAGGTGGAAAAAGTCGAAATGCAGACACAGCCAAACACCGTCCAAATGGATGACCAATCGAACCTACCATTGCAAGCTGATACACAGCCTCAAAATGAGTCCGCAAATCATTCACCATTTGAATCTCCCATATCATCACCTCAAGTTCAGTCTCAGATCGAAATACAAATGGAACCTCAAATCGAGACTCAGATGCAACCTCAAATTGAGACTCGAATGCAACACGATGTGCTAAGCGTGCAATCTCCACAAAACCATCAGCCTCAAGTACAATCTCATGACCAATCTCAGATGCAACACCAAATCCCACCGCAAATTGAGCCTCAAATTCAAGTCCAAAACCAGGAGCAACATACTTTACAGCTCGTGCCGCAAGCACAGCAACAAGTGGCTCCACAAGTACAACTGCAGTCCCAGTTGGTGCCTCATGTCCAGTCGCAGGGCACGACGACGACAGTCACCTACGAACAGATTTACCAGCAGCACATTGTCCAGCAGACGGTGCAGCAATCCTCCAACAAGATGCAGGTCATCTCGCTGCCCTCGGCTGGCTCGGAAACAACACGACAGTGGCAGACGCAGCAgtcgcagcaacagcagcaagtCCAGTGGTCATCGGTGGGCGGACTTGAGGCCATAAAGAGTGCACCCGTCGAGAGTGTTGCACCCACGACCACAACGTACTACATCAGTGCGAGCGATCTTTATCCGCAGCAGACTGAAACATACACTATGCTTCAACCAGCATCCAATGAAAGCTACGTGATCGAGCAGGTGAAtcaccaacagcaacattgCCAGCAACAGATTCAGATgtcgcaacagcaacagcaacagcaacgccAGCATCAGCAACGGCAAGCGCAGCAggcgcaacagcaacagcagccgatTATGATACTGATCCAGCAGCCGGAGCAGCCAGTGGCCTCGGCCAGCAATCCGCAGCAGGCACCGCTGCACATCTATAATGCTGCCACCAGCAACGATGTCCGTCAAATGCAGCACACGCAACGCCAACAGATACGGCAGCAGTATCACCACCAGCAGTATCAGCGGCTGCAACAGCCGCAACAAACTCGCGTCGTACAAAGCCATCCAGTATTGGGAATGCCGGGAGCCACTTCCATATCAACGAAAGTGACCCCCATTCCCGTCACAGCGGCCAGGGGTCGGGCGCTCACGCTGAAGTGCCGCTTCTGCCATAACGGGCCGCGATTCTCCAGCAGCCTGGAGTACAGCCGGCATATCATAGATCTGCATCCGGCGGTGGCGCCCTTCAATTGTCCGCACTGTCCGCAGGCCTTTGCCGGCAGAACGAAGCGATCGCAGCACATCCTCAGCCACCATGTGGTGCAGCAGTACCAGTGCGGTCAGTGCTCACAGGTGTTTCCCGCCCAGAAGGCACTGGACGTTCACATCCAGCGCATTCACATGACCCTGAAAACGGATCCATCGGGTGCTGTGAAGGTGGAGGACGTTCAGCTGCAGGTCACCAGCGAACGCAGGCCACGGGGTAGGCCGTATAAGCCAAGGCTACAGCTTCAACAGCATCAACTGCAGCCGCAGCAGAAGTTgcaagtgcagcagcagcagcagcaaaaggcACTTCAGCAACTACCCCAAGCACaacaccaccaacagcaacagcaacctCAACTGCAACAAGAAGTGCTACAGCAGGTGCAGCAACTGCAAGTGCAACCGCAGCAACAAGTGCatcagcaacaccagcaacagcagcaacatgtgtTGCAAGTGCAGCAACCACAGCAACAACCGTTAATGCAGCCACAGTCGCCGCATCCATCAACAGTGGAAATGCAAGCAAGCCCAACAACGCCACGAAAGATTCTTTGCTGTCCCGATTGCGAAGACTGCACTTCCGGTCACAGCCATGCCAACGAACAGTTCGAGGAGCTGCAGACACTGCAGGCTCCGCCAACGGTGTTGACTCCGCCATCGACCATAGTCTCGGTACCATCGCCACAGCCCATGGTGTACTCGCAGCACATAACAATGCCGTCGCCGGAACAATCCGAGCCAGATTCCACGACCACGTTGCGACAGTATCGCAAGCGAGGCGTGATCGTTGGGCCACAGGGTCCGCTGCATTTGGCCACACCGGTGGCCTCGCCATCGCCCTCGTCGTCACCCTCCTCATCGACGGTGGATCACATACCGCCGGCGTCTCCGGCTCCGCCCGCATCACCAGCTCCGCCTCCGTCGCCCGCCGTCGCGTCCACGGTGCAGGTGAGCGAGCTGCGGACGAGCCACCATTGTCTGTACTGCGAGGAGCGATTCACCAATGAAATTTCCCTGAAGAAGCACCATCAGTTGGCGCACGGAGCGCTGACAACAATGCCATTTGTGTGCACAATCTGCAAGCGAGGGTATCGCATGCGTACGGCGCTGCATCGGCACATGGAGTCGCACGACGTGGAGGGACGGCCGTACGAGTGCAACATTTGTCGCGTCCGGTTCCCGCGACCATCGCAACTGACGCTGCACAAGATCACGGTGCACCTGCTCTCCAAGCCGCACACCTGCGACGAGTGTGGCAAACAGTTTGGCACGGAGAGCGCCCTCAAGACGCACATTAAGTTCCACGGAGAGCTCGGTTACCAGTGCGACGGGTGCGATCGGAGGTTCGAGTATCTGAAAGAATTGCGCAAACATCGACGCACCCACAGCGAGATGttttacaaatgcaaattCTGTCCAAGCTCCTTTATGCGTTTCACGAATTTTCGGGCTCACATGAAAACCCATTTGCCGCTGAGCGTATTCCGCAACGAGGATGCCGCATCGAAGTCACCCAGCAACAATAATAGCCACGCCAGCAGTGACAAGCTGGAGAATCCAGCCACGCCCATCGAGGAGACACCTTTGACGCCGATGAGCAGCGGCGGACACGTGTACCACAGCCCAGACGAATACCCCAATTCGGTGGAGAGCTGTGCTGGCAACAGCGTGGCtctggaatcctatgccacaacgCCATAA
Protein Sequence: MSANRRRRSASAASAIAAERATAAAAAEAISTAPSKEQLSPPIAGGSASADEDLLEMPRICRCCCKRDLKLLGLFEASQPTLANTTVASASVASNKSSGTLAKTCATEAETETPQTLSANPVNPGTKATSSPSEAATTLSASTHPASASFSSTSSSSTSTSPMRRRTTNTTAPSAPPAPRGRSSDNAVDYTLSGAHSSMDIVLEEMTIWMLNINRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDFAQEISDRQTARQAKRQQKVQKKTHDSWLQLEPTSHEEQQPIRKRRMVSESDGDSTAAAAATATTPAKQVRTEFENLPPPKPSPQQHRVRKYRTLSIGCEMERPAASINASSMPWKTKAARKQLSESRASSCSTAVMSPNRQRSSTSSSEHMSDLSVGPCCGFESDSSPSSTSNSARRSVILVKQQSPEKTSPMYDLMPRRGRRPRKAPIYMPAKRQRRSLVRKEPLNRKAAAQPVNEENKKSDQKDIYPKEPRKEGLGPSCDEAIDSTSDAPMEVASNVVQKKCDEINLNDLMLCKMQKDITSNGLIDSRDQLGAMEMEPVNEMIASNGVVKELPQAEMHVLNAQNYEETSSEKQTLEATSVIKESIQSEPTAVRTEIESIGNDIRAGSDLVQSEELTSSTETSELQRKTVQQLETMGQQESCATLQTMKNEASVQLTETADESDSADQREIIVSIPLEVLDENLQRRLCVDPETEAANRQSADPKEFPLRPDDVNNNENDENFCQSATADSFNSAVALRTNKIEATPPGGTESDDTDTEEVPIVRSGPTPMDFMAEFAKHCANGIEQLKVTTPAPSPTPSDLVPLNDLEAKQKLEVEMNDVETTLNGILNEMQDQHMYTPNCAHIDEFLTPADYATLTEQESPVSSPPNPFEQNSIAEPKDEKPNATEDPFDNSNFTNELIGFQNDIPCFENIETPEQGQNLHLELTQFLRDLQPAQSDPPAEEQVEKVEMQTQPNTVQMDDQSNLPLQADTQPQNESANHSPFESPISSPQVQSQIEIQMEPQIETQMQPQIETRMQHDVLSVQSPQNHQPQVQSHDQSQMQHQIPPQIEPQIQVQNQEQHTLQLVPQAQQQVAPQVQLQSQLVPHVQSQGTTTTVTYEQIYQQHIVQQTVQQSSNKMQVISLPSAGSETTRQWQTQQSQQQQQVQWSSVGGLEAIKSAPVESVAPTTTTYYISASDLYPQQTETYTMLQPASNESYVIEQVNHQQQHCQQQIQMSQQQQQQQRQHQQRQAQQAQQQQQPIMILIQQPEQPVASASNPQQAPLHIYNAATSNDVRQMQHTQRQQIRQQYHHQQYQRLQQPQQTRVVQSHPVLGMPGATSISTKVTPIPVTAARGRALTLKCRFCHNGPRFSSSLEYSRHIIDLHPAVAPFNCPHCPQAFAGRTKRSQHILSHHVVQQYQCGQCSQVFPAQKALDVHIQRIHMTLKTDPSGAVKVEDVQLQVTSERRPRGRPYKPRLQLQQHQLQPQQKLQVQQQQQQKALQQLPQAQHHQQQQQPQLQQEVLQQVQQLQVQPQQQVHQQHQQQQQHVLQVQQPQQQPLMQPQSPHPSTVEMQASPTTPRKILCCPDCEDCTSGHSHANEQFEELQTLQAPPTVLTPPSTIVSVPSPQPMVYSQHITMPSPEQSEPDSTTTLRQYRKRGVIVGPQGPLHLATPVASPSPSSSPSSSTVDHIPPASPAPPASPAPPPSPAVASTVQVSELRTSHHCLYCEERFTNEISLKKHHQLAHGALTTMPFVCTICKRGYRMRTALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIKFHGELGYQCDGCDRRFEYLKELRKHRRTHSEMFYKCKFCPSSFMRFTNFRAHMKTHLPLSVFRNEDAASKSPSNNNSHASSDKLENPATPIEETPLTPMSSGGHVYHSPDEYPNSVESCAGNSVALESYATTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00504951;
90% Identity: iTF_00596902;
80% Identity: -