Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: -
Assembly: GCA_018153235.1
Location: JAECXV010000008.1:10107275-10111349[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2e-05 0.0015 18.7 0.5 1 23 153 176 153 176 0.96

2 14 0.0027 0.2 12.0 2.8 2 23 225 247 221 247 0.88

3 14 0.0079 0.58 10.6 0.5 1 23 345 368 345 368 0.92

4 14 0.042 3.1 8.3 4.6 3 23 418 439 416 440 0.95

5 14 0.00029 0.021 15.1 1.1 1 23 500 523 500 523 0.92

6 14 7.1 5.2e+02 1.3 0.0 2 14 542 554 541 566 0.83

7 14 0.00017 0.013 15.8 3.1 2 23 574 596 574 596 0.97

8 14 0.024 1.7 9.1 1.5 1 23 699 722 699 733 0.94

9 14 0.0012 0.091 13.1 0.2 1 23 753 776 753 776 0.92

10 14 0.002 0.15 12.5 1.5 2 23 826 848 825 848 0.95

11 14 0.019 1.4 9.4 2.1 1 23 939 962 939 962 0.91

12 14 0.011 0.78 10.2 1.0 1 21 1014 1034 1014 1035 0.95

13 14 4.3 3.1e+02 2.0 0.1 3 23 1073 1096 1071 1096 0.78

14 14 0.83 60 4.2 1.4 1 23 1114 1138 1114 1138 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2e-05	0.0015	18.7	0.5	1	23	153	176	153	176	0.96
2	14	0.0027	0.2	12.0	2.8	2	23	225	247	221	247	0.88
3	14	0.0079	0.58	10.6	0.5	1	23	345	368	345	368	0.92
4	14	0.042	3.1	8.3	4.6	3	23	418	439	416	440	0.95
5	14	0.00029	0.021	15.1	1.1	1	23	500	523	500	523	0.92
6	14	7.1	5.2e+02	1.3	0.0	2	14	542	554	541	566	0.83
7	14	0.00017	0.013	15.8	3.1	2	23	574	596	574	596	0.97
8	14	0.024	1.7	9.1	1.5	1	23	699	722	699	733	0.94
9	14	0.0012	0.091	13.1	0.2	1	23	753	776	753	776	0.92
10	14	0.002	0.15	12.5	1.5	2	23	826	848	825	848	0.95
11	14	0.019	1.4	9.4	2.1	1	23	939	962	939	962	0.91
12	14	0.011	0.78	10.2	1.0	1	21	1014	1034	1014	1035	0.95
13	14	4.3	3.1e+02	2.0	0.1	3	23	1073	1096	1071	1096	0.78
14	14	0.83	60	4.2	1.4	1	23	1114	1138	1114	1138	0.89

Sequence Information

Coding Sequence: ATGTTCTCCTCAGATTTCGATGAGGCGGAGGATGGGGTGGAGGGAGAAGCTGGTCTGGAGGGGGAGGATGGCGAGCAGTACGGCAATGGAAATGGAAATTCGGATCTTTTGGATGCCGACATGGGCGATGACGACATCCTGGATGGTGAGGAAGAGGACAGGGAGGAGGAGGAGGACGAGGACGATGGTGAGGGGGAAAATAGAGGAAAAGGATCCGGTCCCGATCCGGACGATGATGCCATCTTCGACTTTGAACTGCAGCCCATGATTAGCTTGTCGGAGCAGCCGGAGCAATCGTCCTCTTTGGACGACACTGAGGACACACTGCGAGGGCAGTCGGTGCCCGGCTCCCAGGGTCGTAATCCCAATGTAGGCTATCCACAGCGGCCAACTACCTCGCAGATCAATGCCACGGACGAGCACGGAGTGCCCATCAACTACGAGCTGGGCGTTGTCTACATCTGCCCTGCCTGCGGCGCGGAGTTCCGGCAGCAGGATCACTGGAAGCGACACATGAACCAGATGCATCGGTACAACACCTTGCGCGGCCTCAACTTCCTGCCGGTGGACAAGCTGTATCATCGCTGCCAGGAGTGCCACAAGCGGATTGCGATGCACAGTCGAGAGAATCTGCTGAAGCACAAGTTCACCCACTTGCCGTACAGGTGTACCAAGTGTTACATATGCAAGCGGGAATACAAATACAGGCAAGATCTTATGGTGCACTTGAGGTTAGTGCACTGCGAGGAAGTCGTGGCCATGATGCGGGGCGGCTACAATGCAGCTGGCCGAAAGACCCGTGTCCGGGAGTCTCGCACCGAACAATTGCAGAGGGAGGAGGACGGCGAGTTGGATCGCATAGAGGTGCGCAACGAGGTGCTCGAACCGGACGCCGATGAGTCGAGTGTTTTGGAGCATTCAAAGCAGTCACTAGTCGCAGAGGAGGTACCTCCTGCCAGCAGGAAGAAGAGACCCGAGGAGGAGGGCGATGAACTAATACTCGCTGCAGAGCTGTGCGAGGACTACATTCATTTCATGTGTCCGGATTGCGGTTACGAGTGCGACAACATCAGGCAGTGGCGCCAGCACATCGAGTTTGTTCACGACTTTGTGAGCAGGCGGGGACTAAACTTCCGGAGCAGTGACATGCAGATGCAGTGCCTCGAGTGTAAAAAGATTGTCTCCCCGAACACCATTAAAGTATTGCGAGCGCACAAGTTCAGTCATCTATCGCATCCGGAGTGGATGCACTGCAAGCTCTGCTATAAGGGCTTCTCGGACCACGACGCCATGGTGAAACATCTGCTGAAGGAGCACCACCTGGACACTCTAATGCCAGAGCGAACCGGCCAAGCAGAGGACGGAGAATTCGATGGCGGTGGCAGAAAAGGAGAAGGAAACGGGGATGCATTGGACGACGAGTCGCCCTACTTCGCGGATGCACCTAGACGGGGTGGACGCATCAGTAGCGACGACATGTACGAGCCCTTTATAGACTATCTGTGCCCGCAGTGCGGCAAGGAGTTCCGCGAAAAGAAGCACTGGCGCACCCACGTGGTCATGATGCACGGAATGAACGACCTGTCGAAGCTGAACTTCAATGTGATAGACGAAAGGAAGCTGAAGTGCCTCGAGTGCGACAAAATCATCACCAATGCCTATGGCATCCAGAACGCGCAGCAGCACAGGATCACCCACTTGCCGTTCAAGGCCTACGCCAGGTGCACCAAGTGCCACAAGTCATACACGGACAGGAAGGGTCTGGTCAAGCATCTGGCCACCTACCATCGCATCAACGACATGCCACGAAGATCGACTGGCGGAAGTCTGGGAGGAGATGCTGGTGGCGGGGGAGACCAGCTTCCGTTGCCCCCGGCTCCGAAGCAGCCTCGCAAGCAGATCGTCACGGTGGCCAATGAGACATACGAGATCATCTACCTGGACGACCATGAGCCGGTCATCGAAGAGGACAACGACTTTGGGGAGCAGATGCAAGCGGAGGAAGAGGAATTCCTCCCAGCCACGATTGCCCCGCCGTCGCCTCCAATGCTGCATCCAGCACCCGGACACGTTGGGCAAAACGATGGACATCGCTACAAGTGCATCCACTGCGGCGAGGCCTTCGCTTCCCAGGCAGCCGTTAAGCAGCACAGAATCGATAAGCATTTCAAGATCCGCAAGAGGTTGCGCAGCCACCAGCCCACGCAGAACTCGGACACGATCGCTCCCTTCCCAACGGTGGAGCAGAACTACATCTTCCTGTGCCCCTCCTGCGGCATGGAGTACAAGACCCAGTTCGAGTGGCGGCGCCACATCAACGACGTCCACAACTTCGACAAGCGCGAGTATCTGAACATGCAGCAGCTGGACAAGTACCGCTATCAGTGCACCCAGTGCCGGGACGTCGTTAGCAACTCAAAGCTCAAGGGCCTGCAGGACCACCATTTCCGCCACTTGCCATACCGCTTGTACTTGAAGTGCCTCATCTGCGGTACCTGCTACAACCACAAGCCGAACATAGCGGCGCATCTGCGAGCGCGGCACAACATCTTCGAAAGGGGGGCGCCCGTTATGGTGACCAAACCCAGCAAGCACATGAACCGCTATCGGGAGGTGGACAGGGAGAAGACTCTACCTCCGTCTCCGATACCGGTACCCGACTCTCCACCCAGCTGTTCGCCCTCCTCCTCTGGGGCTGCCATGAGTCGCACCCTGAAGCCCCAGCCGGGGGCGTTACCCGTTCGACCCGCTGGTCTAAACACCCTGGAGGATAGCATCTCGTATCACAATGCCGTGGACTTGGACTTTATCACGTACTTCTGCCCGAAGTGCAATCAGAACTTTGACTCGCACGCCTTTTGGCGAAAACACATCGTGGAGAAGCACAACTTCAACAGTCGCGAGGGCCTGAACTTCCGGCAGCTGGATAACCACCACTACCTATGCCTGGAGTGCTACAAACGGGTGACAGTCACCCACACAAAGGGGGCCATCGGCCAGTTGCAGTCGCACAAGTTCCGCCACCTGCCCCATCGCTCCTTCAAGTGCTTGACCTGTGGCGGGGAGTTCGTGCGCAAGCAGATGTTCTTCAAGCATCTGAATAGGGACACCAATCGCTGCGACAATCACCAGCAGCGGGAGCTGGACGACGACGAGCAGGAACACGACCAGGAGCAGGAAGGAGTGGTGCCCGTGCGGTCTATGTACCAGCTGGCGTGTCCCCAGTGCGGCGATGGCTTCACCACGGTGAAGAGAACAGCATGGAAGGAGCACATCAATGTCTACCACAGTCTCACCAAGCTAGACTTGCTGCACATGATCAAGGTGGACGTGGATCGGTACCGCTGCAACGACTGCAATGAGGAGATTGGGACAAACCGACTGCGTGAGCTTCAGCACCACCGGTACCAGCATCTTCCCCACCCTGCCTATGTGCGCTGCAAGATGTGCGACAAAAATGAAGTCGGCTCGGAATCTGGAGGCGGCAGGGTCCACAGCCTGCAAGACCTAAAACAGCACATCCTGAACAGCCACCCGGCAGCAAAGGAAAAGGAATCTATACTAGCCAAGATCCGCGAGCATATGCACCAGGAGGAGCAGGAAGACGTAGTGCCAACTGTAGAGGATGAAGACAACCAGACTGGTCACGATTCAGGGCCATACATGCCATTGCCCCCGCACCTGCTGGATGACGGGGATGATATGGACTTTGAGGATCAGTATCTGCTGGGATAG
Protein Sequence: MFSSDFDEAEDGVEGEAGLEGEDGEQYGNGNGNSDLLDADMGDDDILDGEEEDREEEEDEDDGEGENRGKGSGPDPDDDAIFDFELQPMISLSEQPEQSSSLDDTEDTLRGQSVPGSQGRNPNVGYPQRPTTSQINATDEHGVPINYELGVVYICPACGAEFRQQDHWKRHMNQMHRYNTLRGLNFLPVDKLYHRCQECHKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRLVHCEEVVAMMRGGYNAAGRKTRVRESRTEQLQREEDGELDRIEVRNEVLEPDADESSVLEHSKQSLVAEEVPPASRKKRPEEEGDELILAAELCEDYIHFMCPDCGYECDNIRQWRQHIEFVHDFVSRRGLNFRSSDMQMQCLECKKIVSPNTIKVLRAHKFSHLSHPEWMHCKLCYKGFSDHDAMVKHLLKEHHLDTLMPERTGQAEDGEFDGGGRKGEGNGDALDDESPYFADAPRRGGRISSDDMYEPFIDYLCPQCGKEFREKKHWRTHVVMMHGMNDLSKLNFNVIDERKLKCLECDKIITNAYGIQNAQQHRITHLPFKAYARCTKCHKSYTDRKGLVKHLATYHRINDMPRRSTGGSLGGDAGGGGDQLPLPPAPKQPRKQIVTVANETYEIIYLDDHEPVIEEDNDFGEQMQAEEEEFLPATIAPPSPPMLHPAPGHVGQNDGHRYKCIHCGEAFASQAAVKQHRIDKHFKIRKRLRSHQPTQNSDTIAPFPTVEQNYIFLCPSCGMEYKTQFEWRRHINDVHNFDKREYLNMQQLDKYRYQCTQCRDVVSNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHNIFERGAPVMVTKPSKHMNRYREVDREKTLPPSPIPVPDSPPSCSPSSSGAAMSRTLKPQPGALPVRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEKHNFNSREGLNFRQLDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCGGEFVRKQMFFKHLNRDTNRCDNHQQRELDDDEQEHDQEQEGVVPVRSMYQLACPQCGDGFTTVKRTAWKEHINVYHSLTKLDLLHMIKVDVDRYRCNDCNEEIGTNRLRELQHHRYQHLPHPAYVRCKMCDKNEVGSESGGGRVHSLQDLKQHILNSHPAAKEKESILAKIREHMHQEEQEDVVPTVEDEDNQTGHDSGPYMPLPPHLLDDGDDMDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615746;
90% Identity: iTF_00488298;
80% Identity: -