Dmal000503.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila malerkotliana
Gene Symbol
RREB1
Assembly
GCA_018153235.1
Location
JAECXV010000036.1:1248900-1254891[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0047 0.35 11.3 0.6 1 21 245 265 245 267 0.96
2 13 0.00027 0.02 15.2 0.2 1 23 277 299 277 299 0.98
3 13 6.5e-05 0.0048 17.1 7.3 1 23 305 327 305 327 0.98
4 13 1.7 1.2e+02 3.2 3.7 2 19 548 565 548 567 0.97
5 13 0.0068 0.5 10.8 0.1 1 23 712 734 712 734 0.97
6 13 1e-05 0.00073 19.7 0.7 1 23 744 766 744 766 0.99
7 13 0.00067 0.049 13.9 2.0 1 23 772 795 772 795 0.97
8 13 0.0024 0.18 12.2 2.0 1 23 1064 1087 1064 1087 0.95
9 13 7e-05 0.0051 17.0 0.3 2 23 1449 1470 1448 1470 0.97
10 13 0.12 8.6 6.9 6.3 1 23 1476 1499 1476 1499 0.97
11 13 1.3 99 3.5 2.1 1 23 1621 1644 1621 1644 0.91
12 13 0.0068 0.5 10.8 0.5 3 23 1711 1731 1709 1731 0.96
13 13 0.0052 0.38 11.2 5.7 1 23 1737 1759 1737 1759 0.99

Sequence Information

Coding Sequence
ATGCTGGCAGCAGCGCAGCAGCAGCAGCAGCAGCAGCACAATACCACCAACAACAACCCAAACACAACTACCACAGAGAACGAGATGGAGCGCCAGAGGCGGGACTCCACCACCTCGGAATCCTCGCTGGAGCACCTGGATTTGGGGCGCACGCCCAAAAAGCTCAGCGCCGTTAGCAGCGGCGGCAGCGGCAGTCTGGTGCTGCAGCCGACGTCAACGCCACACGAAGTAGCGACAGCGACGTCGCGCAAACGTAAGCTCCGCCAGCTCCAACATCATCATCAGGACCTACTCAGTGATGAGGACGAGGAGGAGGACGAAGCGACATCGGGGGTTGGAGCCCGCCCCCATGGTCGTCAAAAGCAGCGACGCAACGCCTCTGCCTCGGCCAGCATCGTGCTGGACGGTAGCGGCAGCGACGCCAGTTCACTGCGCAAGAAGTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGGATCTTCGCCGCAAGGTGGCCTGTGCCTGTCCAGCGGCGAGTCCGGCATTGGGGCGGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCAGTGCCACGCCCCACGAGTTCACCAATCACATTCGGTGCCACAACTACGCCAACGGGGATACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCCGCCTCATCCCTGGACAGACACGTGCTGGTGCACACCGGCGAGCGTCCCTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGGAACATGCACCGCCACATGCGCACCCACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGCCTAAATCCCGCCCAGCAATCGCTGTCGGGACGGGCGGAGAGCTATGAGAGCGACGCCAGCTGCTCCACAGACGCCTCCAGTGGGCATAGCCGCAGTCGCAGCAGTTCCTCCCTCACCCACAACAACAACAACTCCCAGAAGGCCAACCACAACCACAAGGACATAGAGCTGGACCTGGAGCTGGAGGAGGAGGTGAAGCATCATCAGAACCGTCGCGGGCTCAAGACAACCATAAACAACAATGTCATCGAGAGCGAACACGAGGACGAGGAGGAGGAGCAGGATCACGACGATGTCGATGAGGAGACGGATGTGGCCATGCTGACATCCACTCCCGATGTGGCCACCCTGTTGGCCGGAGCCAGTGGCTCGAGAGCCGCCTCCCGATCTGTCTCCCCCTCGTCGGCTGCCTCGCCGGCGCTCCTGCTCAGCTGCCCCGCCTGCGGAGCCGGGGATTTCGAGACGCTGCCATCTTTGTGCGACCACCTGGACGCCCGGCACTCGGACATCCCGGCCAAGTGTCGCGATTGCGAGGTGATCTTCGCCAGCCACCGCCAGTTGCAGGCCCATTGCTGTCGCGGCGGAGTAGGACGTCCTGTTGGTGTGGGTCTGCCGCCTCTTATGGGCGCCAGCAGCTCCCCACTCCACGGCGACGACGATGCCGAGGACGAGGATGATGAGGATGCGGAGCGACGTCGCCTGGACAAGCAGCGCCTGGCCGAGCAGCGCGAGGACTTCTTCCAGCAGCTCTACCTCAAGGGCAAGACCTCCGGCGAACACCCGCCCTCGCCGATCAAGCATGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTGCACCAGCAACTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGACGGGCGCGACCAGGAGGAGGAGGCGCAGGATGCCTTCACCTCGGAGTTCCGGCGGATGAAGTTGCGCGGCGAGTTCCCCTGCAAGCTCTGCACCGCCGTATTCCCGAATCTGCGGGCCCTCAAGGGCCACAATCGCGTCCACCTAGGCGCCGTGGGTCCGGCCGGGCCCTTCCGCTGCAACATGTGTCCCTACGCCGTCTGCGACAAGGCCGCTCTGGTGCGGCACATGCGCACCCACAACGGAGATCGCCCCTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGAGGCATCTGCGGAACCGGCACGGCAAGACCAGCCGGGAGGAGGTGAAGCGCGCCATCATCTACCATCCGGCGGAGGACGCCGGCTGCGGCGAGGACGGCAAGTCCCGTCTGGGCGAGGATCTGGATCTGAGCTTCCGCTCGATCAGTCCGACTCCCCCGCCACCACCGCCACCGCTCCCGGAGAGCAGCTCCCAGCTGAAGCACATGCTCTTGGGCGAGAATCAGGCAGCCAGTGGAGCTCCCGCTCCCAGCCCCCAGCCTCCGCTGAAGATCCAGGTCAAGAGTCTGGACCAGCTGGTGGACAAGAAGCCCAGCCAGGAGAAGAGCTCGCCCAGCGCCGCCCTGGACTTCAGCATGGACGTGCTGGATCTCAGCAAGAAGCCCTCCAGCGGATCGGCGGCCATCACCCCGACTCCCACACCGAATCCGGCTCCGCTGGCACCTCCCCCGGGAGTGGCTGGTGCCCCGGACCTGGCTGCCGCCCTGGAGCAGCATCAGTTGCTCCTCGCCCAGCAGCAGCTCTTTGCCGGAGCCGCCGGCGATGCTGCCTCCCAGTATGTCCAGCAATTTTTCCGCAGCCTCATGCTGCAGTCCCAGACTCCGGGCTTCTCGTACCTCTATGGCGCCTTCATGGCCCCGCCGCCGCCGCAGACCAACTCGGAGAAGCCCCCGCCGCTGGTGAGCCCGCCCACTCGTGGCCTGAATCCTCTGCCGATGGGCGGTGTGGGCGTGCCAGTGCCTCCGGGCGGACCCGTCAAGATGGTCATCAAAAACGGCGTCCTGATGCCGAAGCAGAAGCAGCGCCGCTACCGCACCGAGCGTCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTTACCCTCCGCAGCAACATGGAACGCCACGTGAAGCAGCAGCACCCCCAGTTCTATGCCCAGCGCCAGAGGAGCGGCCACCATGTGATGCGCGGACGTGGCGCCTCCAATGCCGCTGCCGCTGCCGCCGCCGCAGCTGCTGCCGCTGGTATGGGTGTTCCCGGCGTGTCATCCGCTGGAGTCGGCTCTGGATCTCATCATCATCCCGGCCACGGACACGGACATGCTCCAATCTCCGAGCAGGTGAAGTACGCCATTCTGGCCCAGCAGCTGAAGGCCCACAAGAACACGGATCTGCTGCAGCAAGCCCTGGCCCACGGATCGAGCAGTGTGTCCGGCAATCCTCTCCTGCACTTCGGCTATCCACTGGCCACTCCGCCGCCCAGCTCTGCGCTGCACAACGGTGGTAGCGGGCAGCCGGGAAACGGGGTCCCCATGGTCTCCATGGATGACGATGAGCCCAAGCTGATCATCGACGAGGATGAGAACGACAACGATGTGGAGGAAGTGGAGGACTTCGAAGAGGATGAAGAGGAGGAGGAGGAGGATGAACCGGAGGACGAGCCCGAGATCATTGCCGACGAGGAGCCACTCCCACACGATGAGGAGGAGGACCAGCCGGAAGAGAAGATGGAGGAGCTGGAACTTCCCAAGCCCCTCTTGGAGCAACTGCCCAACGAGGCGGCCCAGAAGACCGCCGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGCCCGTGACCACGCCCCCACCTCCGCCAAAGGACCAGCAACTGGAGCAGCTATCTCCGCCCGCTCCCAGCTCTCTGAAGACCATGATTGCCCAGGCCGAGTCCGTGGCCAAGTCCCTCAAGGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCGCAGGACCTAGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGTAGCGCCAGCGAGAGCAATAACAGCGGCACCGAGGACGTCACCAGCAGCTCCTCCGGCAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTTGCCCCCAACAGGGTGTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCCCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATTCCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGTCGTCAGGAGGCCGAGCGAGAGCGTGAGCGAGAACTGGAGCGTGCCCGAGAGCGGGAGTTGGAGCGGGAGCGAGAATTAGAGCTGGAGCGCGAACGTGAGCTGGCCGAGAAGGAGAAGGAGCGCGAACGCCAGCAGCTCATCCAGAAGTTGGCTGCCCAGATGGCTGCCGCCGCCGCCGTCGCTGCCGCTACCCCCGGAGCTCCGGGAGTCGTCGCACCCGGCAGTCTGGATGCCCAGGCTGGCGGAGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTCGCCGACCGGCTGCAGTGCCTCGAGCACATCAAGCAGGCCCATGCCCACGAGTTCGCTCTGCTCCTCGCCAAGGGCGCCATCGAGAACGAGTCCGTGCTGGGCGAGTCGGCCTCGGGAAATCCCAACCAGCCTCCGCCATCCAGCCAGCAGCCGCACTCCGACGATGAGGGCACCAACGGCGTGATCGGTGGAGCCGGAGGTCGTGGCAAGTACCCGGACTACAGCAACCGTAAGGTGATCTGCGCCTTCTGTGTGCGCCGCTTCTGGTCCACCGAGGATCTGCGCCGCCACATGCGCACCCACTCCGGGGAGCGTCCGTTTCAGTGCGAGACCTGCCTCCGGAAGTTCACCCTCAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGTGGACGCGCCCACAACGGCGATGCTCCCGGCTCCGACTGCTCCGACGACGAGCAGGTGAGCAGCAGCCCTCCCGGCACCCCGGCCCCACCCACGGCCACCACTGCCGCCACCAATAACAACAACAGCTGCCACACCAACAACAACAACACAGTGAGCGCCAAGCTGGGCCTAAAGCTGCCCAAGCTGCACGAGCTCCTGGACAAGGCGACGGAGTGGCGGGCCAGCCGGCTGACTGGTGAGCACAAGGAGAACCTTGGCGAGGCCACCGGCCCCTCGGGCTCCAGCACAGATCTGATCGGTAACCTCCTCGGGATCAGTGATCAGGGAATCCTCAACAAGCTGCTGTCCTCCGCCGACGAGGCGGCCAAGCTCCTCGGCGTGGACAACAAATAA
Protein Sequence
MLAAAQQQQQQQHNTTNNNPNTTTTENEMERQRRDSTTSESSLEHLDLGRTPKKLSAVSSGGSGSLVLQPTSTPHEVATATSRKRKLRQLQHHHQDLLSDEDEEEDEATSGVGARPHGRQKQRRNASASASIVLDGSGSDASSLRKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSSPQGGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLNPAQQSLSGRAESYESDASCSTDASSGHSRSRSSSSLTHNNNNSQKANHNHKDIELDLELEEEVKHHQNRRGLKTTINNNVIESEHEDEEEEQDHDDVDEETDVAMLTSTPDVATLLAGASGSRAASRSVSPSSAASPALLLSCPACGAGDFETLPSLCDHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGGVGRPVGVGLPPLMGASSSPLHGDDDAEDEDDEDAERRRLDKQRLAEQREDFFQQLYLKGKTSGEHPPSPIKHEPADSKDLADIQSILNMTSSSCTSNFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIIYHPAEDAGCGEDGKSRLGEDLDLSFRSISPTPPPPPPPLPESSSQLKHMLLGENQAASGAPAPSPQPPLKIQVKSLDQLVDKKPSQEKSSPSAALDFSMDVLDLSKKPSSGSAAITPTPTPNPAPLAPPPGVAGAPDLAAALEQHQLLLAQQQLFAGAAGDAASQYVQQFFRSLMLQSQTPGFSYLYGAFMAPPPPQTNSEKPPPLVSPPTRGLNPLPMGGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAGMGVPGVSSAGVGSGSHHHPGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVSGNPLLHFGYPLATPPPSSALHNGGSGQPGNGVPMVSMDDDEPKLIIDEDENDNDVEEVEDFEEDEEEEEEDEPEDEPEIIADEEPLPHDEEEDQPEEKMEELELPKPLLEQLPNEAAQKTAETILEQAIKAGKPVTTPPPPPKDQQLEQLSPPAPSSLKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERARERELERERELELERERELAEKEKERERQQLIQKLAAQMAAAAAVAAATPGAPGVVAPGSLDAQAGGDLPYKCHLCEGSFADRLQCLEHIKQAHAHEFALLLAKGAIENESVLGESASGNPNQPPPSSQQPHSDDEGTNGVIGGAGGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCETCLRKFTLKHSMLRHMKKHSGRAHNGDAPGSDCSDDEQVSSSPPGTPAPPTATTAATNNNNSCHTNNNNTVSAKLGLKLPKLHELLDKATEWRASRLTGEHKENLGEATGPSGSSTDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504177;
90% Identity
iTF_00580189;
80% Identity
-