Basic Information

Insect: Drosophila malerkotliana
Gene Symbol: -
Assembly: GCA_018153235.1
Location: JAECXV010000008.1:22670121-22675809[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.11 8 7.0 0.4 1 23 1291 1314 1291 1314 0.94

2 13 6.4 4.7e+02 1.4 0.2 1 23 1468 1490 1468 1490 0.91

3 13 0.00014 0.01 16.1 2.7 2 23 1493 1514 1493 1514 0.97

4 13 5.5e-05 0.004 17.4 0.2 3 23 1522 1542 1520 1542 0.98

5 13 4.6e-07 3.3e-05 23.9 4.1 2 23 1549 1570 1548 1570 0.97

6 13 4.3 3.2e+02 2.0 0.4 5 23 1583 1601 1581 1601 0.96

7 13 1.1 79 3.9 5.4 3 23 1608 1629 1606 1629 0.93

8 13 0.027 2 8.9 0.2 2 23 1640 1660 1639 1660 0.96

9 13 1.4e-05 0.001 19.2 0.6 1 19 1666 1684 1666 1688 0.95

10 13 2.8e-05 0.002 18.3 0.4 1 23 1696 1718 1696 1718 0.98

11 13 8.2e-05 0.006 16.8 7.6 1 23 1724 1746 1724 1747 0.96

12 13 0.00037 0.027 14.8 6.6 1 23 1752 1774 1752 1774 0.98

13 13 0.0021 0.16 12.4 6.1 1 23 1780 1802 1780 1803 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.11	8	7.0	0.4	1	23	1291	1314	1291	1314	0.94
2	13	6.4	4.7e+02	1.4	0.2	1	23	1468	1490	1468	1490	0.91
3	13	0.00014	0.01	16.1	2.7	2	23	1493	1514	1493	1514	0.97
4	13	5.5e-05	0.004	17.4	0.2	3	23	1522	1542	1520	1542	0.98
5	13	4.6e-07	3.3e-05	23.9	4.1	2	23	1549	1570	1548	1570	0.97
6	13	4.3	3.2e+02	2.0	0.4	5	23	1583	1601	1581	1601	0.96
7	13	1.1	79	3.9	5.4	3	23	1608	1629	1606	1629	0.93
8	13	0.027	2	8.9	0.2	2	23	1640	1660	1639	1660	0.96
9	13	1.4e-05	0.001	19.2	0.6	1	19	1666	1684	1666	1688	0.95
10	13	2.8e-05	0.002	18.3	0.4	1	23	1696	1718	1696	1718	0.98
11	13	8.2e-05	0.006	16.8	7.6	1	23	1724	1746	1724	1747	0.96
12	13	0.00037	0.027	14.8	6.6	1	23	1752	1774	1752	1774	0.98
13	13	0.0021	0.16	12.4	6.1	1	23	1780	1802	1780	1803	0.96

Sequence Information

Coding Sequence: ATGGTCGACAACAGTGTCCAGTGCCCCGTGTGCACCTTGTACCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACTCATCCCAAGGAGCAGGTGATCAAGGCACTGGTGCAAATGACGATCGTAGGACCTGGATCTGGGAGCGGCGGCAGTGCCCTGGCGGCCGCAATGCTGGCAGGAGCTGGGGGCGGTGGAGGATCAGGTGGTAGTGCAGCGAGTAGTGTTGACACCATCGCAGTAGATGACAAAACAGCTATTGCGCCTTTGAATGCCGAAGTGAAACCAGTTGTGACAGCCAAATCCATATCAGCTGGAACGCCAGCGGTGCAGACGCAGACGCCGCCGCCGCCACCGCCGCTCTCCTCAACTCTACCAACGCCCGCCACCACCTCTACCTCCGCCGCAAACAGCTCCAAATCCCCAAATAGCAACAAACTGAGCAATCCACCGATAAAAGCACTGAAAAGCGCACCGCCCCCGACTGAGGCGCGAGCCAACACATCCGCACATCCCACCACAAGCAGCATGTCCAGTAGTCTGTACCAGCCAACGCTGGTTACCCCGGATTACCGCTTCAATCACCCACAGCAGCAACAGATGTTTGGGCGTGGCGGCAATGCTCCGACAGCCACACTGGTGATTCCCCAAGTGCCCCAGCAGCACTTCCTCGCCAACTCCCAGCAACAGGCACACTTCTCCCATCAGCAACAGCAACAGCCGTCGACGCAACACCAGCCTCCACAGCAGCAGCAGCAGCAGCCGGCCTTGAAATACACCTACGCCACTGCTTTGCCGCCGCCACCGCCGCTGCAGCTCTTCACACAGCAGCAGGCCCTGCCGGCACCTGCAACGCAAACCAATTCGCCGCCACACGTGAAACCTCCGCCCGCCTATGGAGCCGCTATCAGTCAAATACGATCTCAGCACAACCAAAACAAACAGCAGCCGCAGCAACAACAGCTGCAGCCGCAACCCCCACACGTAACCGTGCACCACAATCACAATCTAACCCTGACACCACCGACACCAGCCGCGGCATCATCAGCAGGACCTGCAGCTGGCAAGCAGCTTGTTTCTAGCAAAGCCCATACGGAAGTTTTCCTGAATCCCCCACCACCGCCGTCGCAAGCACAGATCCAGAATCTTGGCCACCAGCAGAATCCAAACATAAGCACGCATGCTAACCCCCAGCTGCTGGGAACATCGCCCTCCGGCAGATTACATCCGCAGCATCAGCCCCTCGGCTTGCAGGCCTATGCCTCTGGCTCAGGAGCCAGCAGCAGCTGCAGCTCCTCGCTCTCGCTGTCGGTTGGTGCATCCAGCTCCACATCGGCCAGCATTCGCGGCCATCGTCAGACCAACTCGCCCTTCGGGGCATTGCTTAATGCTGCTGCGGCTGTTGCCTGCCCTTCGCCTGCCTCGTCCACTGCATCTTCGTCAGTGCTGCGCTACGCAGAGTCGCCGGTGGCCCATTACTTGGAACGCGAGAACGGAGACTTCATTGTCCAAGAGACTCCCAAGCACATTGTGGAGTGCGTGGAGAAGGAAGATGGCGAGTTCTCGGTGATTGAGCGCATATACCAGTCTCCGCCGAGCGTCTTGCATATCCACGATGAGGACGAGGACGATGAGGAGGAGGAGGACGCTGAAGACGCCCACGAAGCGCCGCTGGAGGACGATGACGGGGATGACGAGCGAGAGGAGAACAGTCGAAGTCGCACCAAGGCAACCAAGAAGTCCCGAAAGACGAAGTCGAAGCGAAACTCCAAGCGTCTGTCGGACGATGAGGAGTTCATGAGCATCAGCAGTGGCTGCGAAAGCGAGCCCGAACGGGAGCGGAAAAAGGATCATCAGACCGCGAACTCTACAACGTCTTCCCTCCCACCCTTAAGCACGGCTCCCTCAACGAGTAGGGCGGCTGCGACGGCCACATCGCCATCCAATACAGCGGAAAATCATTCCAGTTCTGCTTCAAATTCCATATCCGCCAGCACCACCACCAAATCCAAGAAGAACCGGATTACAGTGCTCAGCGACGTTCCGCTCAACATGAACGAGTACCTCGATCTAATGGGAAACATTGTGGCCTCCAGTCGCATTGGGGCGGCTCGTCCTTTTGCCGCTGTGGCTCCGATTCCGTTGGTTAAGGTGGAAAAGGAGGAGCCGCTGGATGAATATGACAATGAAGCTGAGCATCAGCAGCAGCTGGAGCAGAAGCCCAGCTTGGAGCACGGCACCACTAGCGTAATTCGAATGGCCAGTACGTCGGTGGCGGCCACATCCGTTTCGGCCGAGGACCTAACGCAGCCGCCACCCATGAAAGTGGAAGTAGATCCCAACACCAAGCTCCTGCCACAGCGCTTCTCTACTCCCGCCCAGCAACTGCGAGGGCCCAAGAAATTAGTCATTAAACCAAAGGCGACGACGACGGCAACGGCGACAGCTCCAGCGACGAAAAAGACTGACACCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGAGTGAAAGCCTAGAGGCTCCAGCGAGCAGTAGCATTCTGGAAAAGCACCTGACCACCAACAGCGGCCGCAAGCTGCTGCATCATTCGGCGGCGAATGACGATGATGCCCGCGTTCTGCTGGAGTTCGCCAACTCCAAGCAACCACCTCCGTTGGCTGCCGCTAGCACCACTTTTGTGGTGAACGCCAATACTGGATTCCCATCGGCAGGATCCGTTTTCGCCAGCACCTCCAAATCAGCAGCTTTAAGCAAACCAGAAGACGAGTACATTCTTCCAGACAACAATCTAGATGTGGATGAGATTGTGATATCCTCGTCGTCTTCCTACGCCTCCTCGGCGGCGCAGGTGCAGGCCGCGCTCCAACCGCCGGACTTCAACTTCCTGTACCACCAGCAGACCACCAGCACTACCACAGTCACCACCGGTGCATACTTCAATGCCTTCTCCAAACAGCAGAATCTCCAGCAACATGGAGCGAGCGACGCCACCAATGCAGCCACTCTGGCCTCATCTTCCAGCAATTCCATGGACCACGACTCGATGAACGCCACATTCCGCGTGGCTAAGACTCAATCGCAGTCCTGGTATCAGCAGGACCACGACCAAGATGCACATAATCAAGGTGGCGTGGGAGCCGGATCCGGTGCAGCTTCTGGTAATCAGGGTCACGATGTTGTGGCCCAGCCGACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCGATGCCAAATATCTGGATCTGGACGCCTGCAAGCGGGAGCAGCTGAGCAGCAGCAACTTGCCCTCGGCCTCCGCCTCCACTTCGACCACATCGTCATCGTTCGCTGGAGCTGGCACGGAAAGCAGCTTGGTGGGCGGCTTGAACATTCGTACAGATGAGAAGATGCCCGCCAAGGGTGAAATCTCGGAGCAGGAAAGCAACTGCGATGTTGAAAACTCGTGGAGCGAATCGGTATACGGCGATATTTCACAGCGGTACTTTAGAAATCAGTTTTCCGGAGGATACAATCCAGAATGGCGGCAGGACTACTTTCCCACTCATGATCTAAGCGGTCAGCCACGAGAGCAAAAACATTTCGACTTCAATGCACTTGATGACGAGGCGTCATCCAGCTCGAGGAAGAGCGATCTGTTGGACATTGACCCTACGGCGGGCACCACCTCCTCCATTTGTACTTCCACGTCTTCGGCTTTGCTGGCTGGTCCACCCATAGCCTCGACTTCGCGGGCGGCTGCCGAGGCGGAGGCGGCTGCCATGGCCATCGCCCAAAGGAAACAGAACCGGCGCAAGCTCTACAAATGCCCCCACTGTGCGTCCATCTTCGAGAAACTGAAGGATCGGAATGCGCACATGATCGGAGAGCATAACTATGTGCGTCAGAACCGTCGGCTCATCTGCACCCAACCGCAGGTGGGAGGTTCCGAGATGCTCCCACCCCAGCAGCAAACAATGCTCCTGCCACCGGCCGAGGGGAGTGCACTTCAAGAGGACTCCAAAGACGGCATTGTGAAAATCAAGCAGGAACAATGCCAAGATAAGACGGATGTGGAGCAAATGCACCAAAACTCCGAACTGCTGACAGACGTCAAGGACTCGGAACTGCTGGGAATCGGGGATGCTGATGGAGACGAGGATGGCGAGGGCGATTTCAAGCCGCCCAGTCAACTGGACGAAAAGATCGTACTACCACCGCTGGCCATGACTACTCCGGCTGCTAAGCTAGCAGCGCTCTATCGGATGCTCATCGCTTACAATGAGTCCAAGCTGGGCCAAGAGCGGAACAACCTCAACGAGCTGGAGCAGAAGGCCATGGAGAAGTCAATCTTCCTGTGCTATGTCTGCCGCACCGACTTTCCATCAGTGAAGCTGTACGACGCCCATCTCACCGAGCACCCGGCCGAGTGCTTCACCTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTTTCACTCCATCTTAAGCGGCATCTCGGGTGGAAGGAGTTCGGCTGCTACGTCTGCGACAAGAAATTCGTGGTACGCAGTGCTCTGGTCGAGCACATGCGGATGCATACGGGCCAAACGCCTCTCAAGTGCAAGATATGCGGCAAGAAGTTTAAACGGTACTCGAATCTAACACAGCACCGGAAAAGGCACACCAAGATGATACTGCGCAAGAAGGAGTACGTGTGCCACTGTGGGGAGGTGCTGCCCTCGAAGGCACGCTTCTTGTGGCACAAGGAAACACACGATCTGAAGCCGAAGTGCTGTCCCTATTGCTGCGATCGATTCGTGCATGCGAACTCGCTGCGGCGCCACATTCGTCTGGCGCACTCGGAAAAATTCGATTACTCCGAGCCGATAGAGTGCCCGATGTGCAAGCAAACCTTCGCCAAAACCTCGATCAAGGCCCACATGGCGACGCATTCGACGGATCCCCAGTACGACTGTACCATCTGCAACAAGAGCTTCTCCACCAAGTGGAACCTCAAGATCCACTCGTGGGTACATGCCAACCGAACGGCCAAGCCTTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGCTGGACTTCAAGAACCACATCAACGCGCACAAGCAGATCAAGCCGTACACGTGCGAGTACTGCGGCTGTAAGTTCATCCGCAAGTACAACTACATGCGGCATCGGCGCGAGCACCACGGAACCAAGAAGTTCACATGCGACCAGTGCGACAAGACCTTCCACCGGCACTACTATCTCGTCGAGCACCGGCGCATGCACACCGGCGAGCGACCCTTCACCTGCACCATTTGTGGCAAGAGCTCCACCACCAAGACCAACCACAACAAGCATCTGAAGATCCATCACTCGCGCGACCCCTTTACTGTCGAGGTCTAA
Protein Sequence: MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGPGSGSGGSALAAAMLAGAGGGGGSGGSAASSVDTIAVDDKTAIAPLNAEVKPVVTAKSISAGTPAVQTQTPPPPPPLSSTLPTPATTSTSAANSSKSPNSNKLSNPPIKALKSAPPPTEARANTSAHPTTSSMSSSLYQPTLVTPDYRFNHPQQQQMFGRGGNAPTATLVIPQVPQQHFLANSQQQAHFSHQQQQQPSTQHQPPQQQQQQPALKYTYATALPPPPPLQLFTQQQALPAPATQTNSPPHVKPPPAYGAAISQIRSQHNQNKQQPQQQQLQPQPPHVTVHHNHNLTLTPPTPAAASSAGPAAGKQLVSSKAHTEVFLNPPPPPSQAQIQNLGHQQNPNISTHANPQLLGTSPSGRLHPQHQPLGLQAYASGSGASSSCSSSLSLSVGASSSTSASIRGHRQTNSPFGALLNAAAAVACPSPASSTASSSVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDEDEDDEEEEDAEDAHEAPLEDDDGDDEREENSRSRTKATKKSRKTKSKRNSKRLSDDEEFMSISSGCESEPERERKKDHQTANSTTSSLPPLSTAPSTSRAAATATSPSNTAENHSSSASNSISASTTTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDEYDNEAEHQQQLEQKPSLEHGTTSVIRMASTSVAATSVSAEDLTQPPPMKVEVDPNTKLLPQRFSTPAQQLRGPKKLVIKPKATTTATATAPATKKTDTXXXXXXXXXXXXXXXXXXXXXXXXXXKSESLEAPASSSILEKHLTTNSGRKLLHHSAANDDDARVLLEFANSKQPPPLAAASTTFVVNANTGFPSAGSVFASTSKSAALSKPEDEYILPDNNLDVDEIVISSSSSYASSAAQVQAALQPPDFNFLYHQQTTSTTTVTTGAYFNAFSKQQNLQQHGASDATNAATLASSSSNSMDHDSMNATFRVAKTQSQSWYQQDHDQDAHNQGGVGAGSGAASGNQGHDVVAQPTXXXXXXXXXXXXXXXXXXDAKYLDLDACKREQLSSSNLPSASASTSTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDVENSWSESVYGDISQRYFRNQFSGGYNPEWRQDYFPTHDLSGQPREQKHFDFNALDDEASSSSRKSDLLDIDPTAGTTSSICTSTSSALLAGPPIASTSRAAAEAEAAAMAIAQRKQNRRKLYKCPHCASIFEKLKDRNAHMIGEHNYVRQNRRLICTQPQVGGSEMLPPQQQTMLLPPAEGSALQEDSKDGIVKIKQEQCQDKTDVEQMHQNSELLTDVKDSELLGIGDADGDEDGEGDFKPPSQLDEKIVLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLNELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMILRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSEKFDYSEPIECPMCKQTFAKTSIKAHMATHSTDPQYDCTICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKTFHRHYYLVEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580145;
90% Identity: iTF_00580145;
80% Identity: -