Dmal015555.1
Basic Information
- Insect
- Drosophila malerkotliana
- Gene Symbol
- -
- Assembly
- GCA_018153235.1
- Location
- JAECXV010000038.1:6375729-6378546[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 1.7 1.2e+02 3.2 1.3 2 23 140 162 139 162 0.94 2 13 0.00033 0.024 14.9 1.8 2 23 174 196 173 196 0.95 3 13 3.7e-06 0.00027 21.0 4.2 2 23 203 225 202 225 0.96 4 13 0.0086 0.63 10.5 9.0 2 23 460 481 460 481 0.97 5 13 1.5e-06 0.00011 22.2 2.9 1 23 487 510 487 510 0.95 6 13 0.00024 0.017 15.4 0.4 1 23 515 538 515 538 0.96 7 13 5.1e-05 0.0037 17.5 5.5 1 23 556 578 556 578 0.96 8 13 0.00013 0.0093 16.2 0.5 1 23 583 605 583 605 0.98 9 13 2.7e-05 0.002 18.4 1.7 1 23 611 633 611 633 0.95 10 13 1.9e-05 0.0014 18.8 0.7 1 23 639 661 639 661 0.98 11 13 2.8e-07 2e-05 24.6 2.7 3 23 669 689 668 689 0.99 12 13 2e-08 1.5e-06 28.2 1.1 1 23 695 717 695 717 0.99 13 13 0.15 11 6.5 4.6 1 23 722 745 722 745 0.90
Sequence Information
- Coding Sequence
- ATGGCATCGCCCCATCCGCAGCCGGGCACGGATCCGGAACAGGAGTCGGAAATCCCGCCCCAGCCGGCGGGATACGAAAAAGTGGATGCCGTGGACCCGGATCGCGTATGCCGTGTCTGCCTTAGAAACGCCACCCAGGATGGAGAGCTGCACTTCATCTTTGCCGAGGTGGCCGTGGAACAGGACGCCAACCTGGCCCGCATCCTCGAGGAGTGCACAGTCCATCCGTGCGAGAGGCAGGACGGGATGCCATCGCACATGTGCGGTTCGTGTGTGGAGGCAGCACGCAATGCCTACCGTTTCAAGCGGGACGCGGAACGTTCTTATTGCTCACTGGTAGGTCTCCTGGGGCGTTCTCCCCAGTTCAAGGCTTCCGGCGCCGAGGCGAGCACCCAAACGGAGCAGGTGGCCCTTTTGTCGTGCGAGCTGTGTCACGACAAGTTCCTGAACAGCATAGATCTCCGTTTGCACCGAAACCGTGTCCACCGGTCGGCGAAAGAGTACAAGGAGGAGGAGCTGAAGTGCAAGTTCTGCCCTCAGAGCTTCCCCCATCTCCGGCAGCTGCGCATCCACCTGGCGAAGAGCCACGACCAGACCGCTCGGCTGCAGTGCGGCCACTGCCCGCGGACGTTCACCCGGAGCGACCATATGCTGCGCCACATGCGCAACATGCACAATCGCTCGGAGGACGATCTTACAGCAGCCTGGGCTTCAGCGGACCACGATGAGACGACTATGGAAGGCGCGGAAGGCGACGAACTGGTCGCCGCTGAGGTCCTGCTCAACGAGGAGGGCGATGACCACGAAGACGGAGCTGCCCTAGAGTGCAATACAAACCCAATTTCCAGCAACGAGGAGGAGGACGATGACAACGACGAGGCCAAACAGGCTCTATGGTTGAACATCAAGCCGGAGCCCTGCCTGGAGGCTGAGGAGGTCGACCTGGTCGCCCAACTGAACCTCGAGAAGAAGCGGCGGCGACGAGAAAAGGCTGTCTTCCCAGCCGAAGCCTCTGGCGACGCCCATGTGAAGAGCGAACCCAGTGGTGACTCGCAGATGAGCATCAAAGTGGAGCGGGGTGGCGACGAAGATGCTTTTATGGGCAGTGAGGACTTCCTGGAGCATCTGCGAGCTGCCGGGGAACTGCCGCTTAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGCAGGGCCGAGGGTTCCGGTTGAAGCAGGAACCTCTAAAGGGTGCCGGCGGGCGTTTGGGGAAGAAAGGAAAGCGACGGCGTCGCCGCAAAAAAGAGGGTTCTCCCACATCCAATCCGGAGAACCGGTGCGAGGTGTGTCAGCGCACCTTTTCGCGCCACTGCCACTTGCTGCGCCACAAGCTGTCGCATCTGGAGAAGAAGCCCCACAATTGCCCGCACTGCCCGAAGGCGTTTGCGCGCAGCGATCACCTGAAAGCGCACGTCCAGAGCCTGCACAGCAACAAGGAGCACAAGTGCAGTCTCTGCGAGGCGGCGTTTGCTCGTCCGGAAGCCTTGGAGCGGCACAAGCTGAGCAAGCATAACGGGGAGGGCCTGGAGCCCGGCAGCGAACTGAAGATGCAACTGGCCGAGCACACCTGCGAGTACTGTTCGAAGCGCTTCTCCAGCAAGACCTACCTGCGTAAGCACACCCTGCTGCACACCGATTTCCTGTACGCCTGCAAGAGCTGCGACGAAACGTTCCGGGAGCGGGCGCTGCTGCGGGAGCACGAGAAGACCCATACCGGGCAGAGGAACTTCCTGTGCTGCATTTGTGGCGATAGCTTTGCCCGAAACGACTACCTCCGCGTCCATATGCGGCGCCACAATGGTGAGAAGCCGTACAAGTGCCGTTACTGCGTCAAGGCCTTCCCCCGGGCCACCGATCTCAAGGTCCACGAGCGCTACCACACGGGCACCAAGCCCAATCTGTGCAACACCTGCGGCAAGAGCTTCCACCGGGCCTACAACCTGACCATTCACATGCGCACCCACACCGGGGAACGGCCCTACAAGTGCGACCAGTGCCCCAAGAGCTTCACGCAGAGCAACGACCTCAAGGCGCACATCCGCCGGCATACGGGCGAGCGCTACAAGTGCCCGCACTGCGACACCTACTTCCTCCAGCTGTACAACATGCGCAATCACTGCCTCACCGCCCACAACAAGCACATCGAGACGAAGACGGGTCGCCTCCAGCGAACGGGTCTGCTGGAAGAAAGCGCTCAGTCGCATCTCACTACGGTGGTGATGCCGCCGGCCCGTTATCCCGCCGGCTCTGATCCCCAGCTGTCGGCCGCAATCGGAGCCGATACCTCCTCCTCCACCACTGTCATCCACTCGCCGGGCGCTTACCAGAACAGTGGCGTAGCTGCAGGGGTACTGGCTCCGGGTACCACCTCGTCGGCGGCGGGAAATACCCTGGACGGGAACAGCTTTGCTCCGTCGAGTGCTCCGTTCGGCGCCTTCAACTTCCCTCCCGTCGTAATGGCACATCTCATGTACAACCATGGCGGTGGCAGTCAGCACAGCCAGAGCGGCAGCGACACCGCCAAATAG
- Protein Sequence
- MASPHPQPGTDPEQESEIPPQPAGYEKVDAVDPDRVCRVCLRNATQDGELHFIFAEVAVEQDANLARILEECTVHPCERQDGMPSHMCGSCVEAARNAYRFKRDAERSYCSLVGLLGRSPQFKASGAEASTQTEQVALLSCELCHDKFLNSIDLRLHRNRVHRSAKEYKEEELKCKFCPQSFPHLRQLRIHLAKSHDQTARLQCGHCPRTFTRSDHMLRHMRNMHNRSEDDLTAAWASADHDETTMEGAEGDELVAAEVLLNEEGDDHEDGAALECNTNPISSNEEEDDDNDEAKQALWLNIKPEPCLEAEEVDLVAQLNLEKKRRRREKAVFPAEASGDAHVKSEPSGDSQMSIKVERGGDEDAFMGSEDFLEHLRAAGELPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGRGFRLKQEPLKGAGGRLGKKGKRRRRRKKEGSPTSNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCEAAFARPEALERHKLSKHNGEGLEPGSELKMQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCDETFRERALLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDTYFLQLYNMRNHCLTAHNKHIETKTGRLQRTGLLEESAQSHLTTVVMPPARYPAGSDPQLSAAIGADTSSSTTVIHSPGAYQNSGVAAGVLAPGTTSSAAGNTLDGNSFAPSSAPFGAFNFPPVVMAHLMYNHGGGSQHSQSGSDTAK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00615033;
- 90% Identity
- iTF_00488150;
- 80% Identity
- -