Dmac001975.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila maculinotata
Gene Symbol
RREB1
Assembly
GCA_035045305.1
Location
JAWNPD010000269.1:1104404-1110527[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.049 3.3 8.4 0.9 1 21 258 278 258 280 0.93
2 13 0.00035 0.024 15.2 0.2 1 23 290 312 290 312 0.98
3 13 8.4e-05 0.0057 17.1 7.3 1 23 318 340 318 340 0.98
4 13 0.25 17 6.2 1.7 2 20 558 576 558 578 0.93
5 13 0.032 2.2 9.0 0.2 1 23 722 744 722 744 0.96
6 13 1.3e-05 0.00087 19.7 0.7 1 23 754 776 754 776 0.99
7 13 0.00086 0.059 13.9 2.0 1 23 782 805 782 805 0.97
8 13 0.0031 0.21 12.2 2.0 1 23 1078 1101 1078 1101 0.95
9 13 9e-05 0.0061 17.0 0.3 2 23 1466 1487 1465 1487 0.97
10 13 0.15 10 6.9 6.3 1 23 1493 1516 1493 1516 0.97
11 13 4 2.7e+02 2.4 3.5 1 23 1622 1645 1622 1645 0.85
12 13 0.0088 0.6 10.8 0.5 3 23 1703 1723 1701 1723 0.96
13 13 0.0014 0.095 13.3 4.8 1 23 1729 1751 1729 1751 0.99

Sequence Information

Coding Sequence
atgctggctacacagcagcagcacacagcagcagcaactcaagttgcagcagcagcagcaacagtagcagcagcagcagcaacaacaacagtaacacaTGAGGATGCTGCAATGGAGCGACAGCGTCGTGATTCAAGCACCTCGGAATCCTCGCTGGAGCATCTCGACTTGGGTCGCACACCAAAGaagctcagcagcagcagcggggcGCCGCAGCCGACATCAACGCCTCacgaggcagcaacagcaacgtcgCGCAAACGCAAGctacgccagcagcagcagcaacaccagcagcagcagcagcagcaaccactcTCCGATGAggaggaacagcagcagcagcagcagcagctggagcctGCAGCGCAGCGAGCGCGTCACAAGCAGCGACGCAGCacaaacgctgctgctgctgctgctgccgctgccggcaGCGCCAGCATTGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGCCTGAAtcgcagcagcgccagcagcaatgCCGGCAACGGTGATCTCTACGAGTCGGGCTTCGTGGAcggcagcgccagcagcgccTATCTGCtgagcaccagcagcagcagcagcgccgctgCTCAGTCAgcgtcggcagcagcagcggtggcagcggcagcggcagcgcagCCAGCgtcaagcagcagctgctcgggCGGCTCATCGCCGCAGGGCCAGTGCCTGTCGAGCGCCGAGTCCGGCATTGGTGCCGGCGACGAGAACATGAAGTTCCTCTGCCCCATCTGCGAGGTCGTCTCCGCGACACCCCACGAATTCACCAATCACATACGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATTTGCTCCAAGGTGCTTTCGTCCGCCTCCTCGCTGGACAGGCACGTCCTGGTGCACACGGGTGAGCGTCCGTTCAACTGTCGCTACTGCCACCTGACCTTCACCACAAATGGCAACATGCATCGCCACATGCGCACCCACAAGCAGCATCAGgccaaccagcagcaacagtcgtcgtcgtcgtcgcagcagcagcagcagcagcaacagttgcagccacagcagcagcagcgacgccagcaacATGGTGGATCGGCAGCAGGATCAGGCTCACAGTCGCTGCCGGCGCGGGCCGAGAGCTATGAGAGCGATGCCAGCTGCTCGACGGATGTGTCCAGTGCGCCcagtcacagcagcagcagcaatcagtccaacaacaacaacaacaacaatagccacaaaacgaacaacaacaatacaaacaacaacaataataataacgagaatgagaatgagctGGAGGATGAGCTGATGATGGCCAACAAACAGCGACGCCCCAAGACaaccatcaacaacaataacatcatCCGGGATGAGCAGCGGGATGAGGATCGGGAGCACGACTCGGATGCGGATAGCGAGGATGTGGCACAGGTAATCACCAGCACACCCGATGTGGCCACACTGCTTGCCTCATCGGGCGGCACCTCGCCCAGcccctcccactcccactcccagtCGCACTcgccgatgctgctgctgcagagctGTCCGGCCTGCAATCTGGGTGAATTTGAATCGCTGCCAGCGCTGTGTGCGCATCTGGATGCGGATCATTCCGATATTCCGGCCAAGTGTCGCGAATGCGAGGTGATCTTTGCCACCCATCGCCAGCTGCAGGCGCATAGCTGTCGGGGATTACGGCCGCTGCTGGGCGTCAGCTCCTCGCCCCTGCacaagcaggagcaggaggacgagcaggagcaggagcaggagcatgATCGTGATCAGGATCAGCAGTGCGAGCAGGATCAGGAGCGAGAGGAGCGCGAGCAGGAGCGTGAGCGCGAAGATTTCTTTCAGCAGCTGTATCTCAAGGGCAAATCCGGTGCGCTACCCTCACCGATCAAGCACGAGCCGTCGGATCAGCGCCAGGATCTGGCCGATATACAGAGCATCCTGAACAtgaccagctccagctgcaccTCCAGTTTCCTGCGCAACTTTGAGCAGTCGGAGAACACACCCTGCTCCAGCCAGTACAGCCTGGACGGACGCGATGGCGAAGAGGAGGCCCAGGATGCCTTCACCAGCGAGTTCCGTCGGATGAAGCTGCGCGGCGAATTCCCCTGCAAGCTATGCAGCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGGTTCCATCTGGGCGCCGTCGGCGCCGCCGGACCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGTGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGGGACCGGCCGTACGAGTGCGCGGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGTGAGCGGCATCTGCGCAATCGTCATGGCAAGACCAGTCGGGACGAGGTGAAGCGTGCGATTGTCTATCATCCCGCCGAGGATGCCAGCTGCGAGGATGGCAAGTCCGTGACAATGGGCGGCACATCACGCCACAATGCCTCCGGCTCCGGCGATCCGGATCTGGCCGAGTTGAGCTATCGCTGTGTGACGCCCACGGAGCACAGCTCATCGGCGGCATCCGCGTGCTCCTCGTCGCACCTCAAGCACATCTTGCTGGCGGATGGTGCGCCCAAGATACAAGTGAAGAGCTTGGATCAGCTGGTCGACAAGCCGCCCGCACTCGATCTCAGCATGGATGTGCTGGACTTGAGCAAGAAGCCAACCattgcacagcagcagctggaccGGGatcgggagcgggagcgggagcgtgACCAGCGGGAGCAACGTGAACGACacgagttgctgctgcaacaacaacagcagcaacaacaacagcagcaacaacagcagcagcaacaacagcagcaattgttTGGAGCGGGAGATGCAGCTACTCAGTATATGCAACAGCTGTTGCGTAATCTCATGTTCCAGCAATCGTCGGGATTTCCCTTCTTTGGCTTCATGGCGCCaccgccgccagcagcagcagcagctggcgacAAGGCAACATTGgcaaacacagcagcaaccgcagcagccaACATTTCGccggcagcaacagttgctgcactgccgttgccgctgtcgctgccgctgccggtgCCGCTGCCCGCCGGCGGTCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAGCGTCCCTTCGCCTGCGAGCACTGCTCGGCCAGATTCACGCTGCGCTCCAACATGGAGCGCCATgtgaagcagcagcatcccCAGTTCTATGCCCAGCGGCAGCGTAGCGGACACCATGTGATGCGAGGACGTGCCGCCGCCTCCAGTGCAGCTgcggcagcagccgccgccgccgccgccgccatgaGCAAtctcagccagcagcaacagttgccacaTCCGCATGGACATCATGGCCATGCACCCATATCGGAGCAGGTGAAGTACGCGATATTGGCGCAGCAGCTGAAGGCGCGCAAGGATACGGATTTGTTGCAGCAGGCGCTGGCACATGGTTCCAGCAGTGtggttgccgccgccgccgccaatgCCAATCCGCTGTTGCATTtcaactacagcagcagcaacagcaacaacaacaacagcagcagcaagcagagtaacaacaacaacaacaacaacaacaatggcagcaatggcaacactTTGGTGCTGGATGATGATGAGCCGCCCAAGCTGATCATAGATGAGGACGATGAGATGCCCGAGGAGGAGGATGACGAGGAGGATGAAGAGGatgaagaggaggaggaggaggatcaAGATTTTGATGCGGAAGAAGAGGATGAGGACGCGGAGGAGGATgagcagctggaggagcagcaggctGCAGAGGAGCCGCTGCCCTCGACGCCCATTGAGGCGGCCAAGAAGGTAGCCGAAACGATCCTGGAGCAGGCAATCAAAGCACAAGCAGAGCCCGCCAGCAAATTGCCAACGGCAATCCCAATGGAGACGGTAGTGCCGAGCAAGCCGGCGACTCCgccgccaacaacaaccacaatgaAAGCAATGATTGCGCAAGCGGAGTCGGTGGCCAAGTCGCTCAAAGAGGTGGCCAGTTCGCCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTACTTCCGTCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAAGGACTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAtgtgaccagcagcagcagcagcagcggcaacgagCCCAAAAAGAAGTCCGCCTACAGCTTGGCGCCGAACCGTGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTGCGGCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGTCCGCTGCTCTTCACCACGAAGAGCAACTGCGACCGGCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAGCCCATCCCAGTGCCCAAGTCCGTCGAGGAGATTGAGCTGGAGGAGCAGCGCCGTCGCCGGGCAGCCGAGGCCGAGCAGGCGGAACGCGAAAAGGAACGCGAACGTGAACTGGAGCGGGAACGGGAGcgcgaacagcagcagctcatccaGCAGCTCCGGCAACAAatggctgccgctgccgcagctgctgctgctgctgccgttgtcgTGGCTGCTCCGCCGCCAACTAGTCCCGGCATGGAGGCCAGCAGCGATCTGCCGTACAAGTGCCATCTGTGCGAGTTCTCGTTTGCGGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCATGCTCACGAGTTTGCGCTGCTCCTCTCCAAAGGCGCCATCGAAACGgatgcacagcagcaacagcagcaacagcagcagcagcaacagttgtcgTCCGTCCATTCGGACGATGAGGCTACGCTGGGCGGACGATCCGGCAAATATCCGGACTATAGCAATCGCAAGGTGATCTGCGCCTTTTGCGTGCGTCGCTTCTGGTCCACCGAGGATCTGCGTCGCCACATGCGCACCCATTCCGGCGAGCGTCCCTTTCAATGCGAGATCTGTCTGCGCAAGTTCACCCTGAAGCACAGCATGTTGCGGCACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGAGCTGGATCACCAGTCCGACTGCTCCGATGATGAGCAGCTGCCATCGCCGCCCACAACGCCCACAGTAGTCGGTGCTGccgtcaacaacaataacaataacaacaacaataacaacaacaataacaatacttgccacaacaacaataacaatagcaaacaGGTGCTGCGTCTGCCCAAGTTGCACGAACTGATGGACAAGGCGAACCAGTGGCATGTGAGTCGTCTCGGCGAGCAGAAGGAAAACATTGCCGAGGCAACACCctcggcggcagcagcagcagcggcggcaacagcggcagcagcagcggcgtcagcagcagcagcagctgttgcaagCGGAGATCTGATTGGCAATCTGTTGGGGATCAGTGATCAGGGGATACTCAACAAGCTGCTCTCCTCGCCAGACGAAGCTGCCAAGCTGCTCGGCGTCGACAAGTAA
Protein Sequence
MLATQQQHTAAATQVAAAAATVAAAAATTTVTHEDAAMERQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHEAATATSRKRKLRQQQQQHQQQQQQQPLSDEEEQQQQQQQLEPAAQRARHKQRRSTNAAAAAAAAAGSASIVVDYSASGDASSLRKKFRLNRSSASSNAGNGDLYESGFVDGSASSAYLLSTSSSSSAAAQSASAAAAVAAAAAAQPASSSSCSGGSSPQGQCLSSAESGIGAGDENMKFLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQANQQQQSSSSSQQQQQQQQLQPQQQQRRQQHGGSAAGSGSQSLPARAESYESDASCSTDVSSAPSHSSSSNQSNNNNNNNSHKTNNNNTNNNNNNNENENELEDELMMANKQRRPKTTINNNNIIRDEQRDEDREHDSDADSEDVAQVITSTPDVATLLASSGGTSPSPSHSHSQSHSPMLLLQSCPACNLGEFESLPALCAHLDADHSDIPAKCRECEVIFATHRQLQAHSCRGLRPLLGVSSSPLHKQEQEDEQEQEQEHDRDQDQQCEQDQEREEREQEREREDFFQQLYLKGKSGALPSPIKHEPSDQRQDLADIQSILNMTSSSCTSSFLRNFEQSENTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRFHLGAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDGKSVTMGGTSRHNASGSGDPDLAELSYRCVTPTEHSSSAASACSSSHLKHILLADGAPKIQVKSLDQLVDKPPALDLSMDVLDLSKKPTIAQQQLDRDRERERERDQREQRERHELLLQQQQQQQQQQQQQQQQQQQQLFGAGDAATQYMQQLLRNLMFQQSSGFPFFGFMAPPPPAAAAAGDKATLANTAATAAANISPAATVAALPLPLSLPLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAAASSAAAAAAAAAAAAMSNLSQQQQLPHPHGHHGHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVAAAAANANPLLHFNYSSSNSNNNNSSSKQSNNNNNNNNNGSNGNTLVLDDDEPPKLIIDEDDEMPEEEDDEEDEEDEEEEEEDQDFDAEEEDEDAEEDEQLEEQQAAEEPLPSTPIEAAKKVAETILEQAIKAQAEPASKLPTAIPMETVVPSKPATPPPTTTTMKAMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSGNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRRAAEAEQAEREKERERELEREREREQQQLIQQLRQQMAAAAAAAAAAAVVVAAPPPTSPGMEASSDLPYKCHLCEFSFAERLQCLEHIKQLHAHEFALLLSKGAIETDAQQQQQQQQQQQQLSSVHSDDEATLGGRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGELDHQSDCSDDEQLPSPPTTPTVVGAAVNNNNNNNNNNNNNNNTCHNNNNNSKQVLRLPKLHELMDKANQWHVSRLGEQKENIAEATPSAAAAAAAATAAAAAASAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00508536;
90% Identity
-
80% Identity
-