Basic Information

Insect: Drosophila maculinotata
Gene Symbol: Zbtb41
Assembly: GCA_035045305.1
Location: JAWNPD010000319.1:6271777-6273475[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 7.5e-05 0.0051 17.3 2.2 1 23 95 117 95 117 0.97

2 11 7.1e-07 4.8e-05 23.6 3.4 1 23 123 146 123 146 0.97

3 11 6.3e-05 0.0043 17.5 1.1 1 23 152 174 152 174 0.97

4 11 1.6e-05 0.0011 19.3 0.4 1 23 180 202 180 203 0.95

5 11 1e-06 6.9e-05 23.2 0.8 1 23 210 232 210 232 0.97

6 11 0.0049 0.34 11.5 1.0 1 23 238 261 238 262 0.95

7 11 0.0035 0.24 12.0 0.1 1 23 267 289 267 289 0.97

8 11 1.1e-05 0.00076 19.9 2.8 1 23 295 317 295 317 0.98

9 11 2e-05 0.0014 19.1 4.7 1 23 323 345 323 345 0.99

10 11 0.0062 0.42 11.2 1.1 1 23 351 376 351 376 0.92

11 11 0.057 3.9 8.2 0.5 1 19 382 400 382 402 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	7.5e-05	0.0051	17.3	2.2	1	23	95	117	95	117	0.97
2	11	7.1e-07	4.8e-05	23.6	3.4	1	23	123	146	123	146	0.97
3	11	6.3e-05	0.0043	17.5	1.1	1	23	152	174	152	174	0.97
4	11	1.6e-05	0.0011	19.3	0.4	1	23	180	202	180	203	0.95
5	11	1e-06	6.9e-05	23.2	0.8	1	23	210	232	210	232	0.97
6	11	0.0049	0.34	11.5	1.0	1	23	238	261	238	262	0.95
7	11	0.0035	0.24	12.0	0.1	1	23	267	289	267	289	0.97
8	11	1.1e-05	0.00076	19.9	2.8	1	23	295	317	295	317	0.98
9	11	2e-05	0.0014	19.1	4.7	1	23	323	345	323	345	0.99
10	11	0.0062	0.42	11.2	1.1	1	23	351	376	351	376	0.92
11	11	0.057	3.9	8.2	0.5	1	19	382	400	382	402	0.95

Sequence Information

Coding Sequence: ATGGTACGCAGCCGTCGCAGCCTCTCCAAGGAGGATGCCGCCTCTGTGCTCACCGACAGCGGCGTCTCGCTGTCATCGCCGCCATCGGCGGCACGCGAATCCTCGCCAGCTGCGACGGCCATCAAGCGGCGCAAGAGCAGCCTCAACAGTCTGCAGGATTTGTATGTGGATGCTGAGCCCGAAGCCGAGCAGGACTCCTCGGATGCGGAGGCGGATGCAGACTACATACAACCGGCGCCAAAGAAATCACCACGCAAGGCGGAGACAAGTAAACGCAAGCAGCACGTGTGCAGCCATTGCTCGAAGGAATTTGGTGGCAAAACCGATCTGCTGCGACACATGCTCATCCACTCGGACGAGCGACCGCACAAATGCAGCGAGTGCGGCAAATGCTATCGACAGGCGGTGAATCTCAAGAATCACATCACCACTGCCCACGAACACAAGAAGCAGTTTGCCTGCACGCAGTGCTCCAAGTCATTTGCTCTCAAGGAGCGCCTCCGGCTGCACATGCGTCTGCATTCCGGCGAAAAGCCATATCCATGTGCGCTCTGCGACAAACGTTTCGCCCGTGGGGGCCAGctacagcagcacATGGTATCGCATCACAAGACGAGCATACAGCAATTCAATTGCACTAAATGCTCGGCCAGCTTCTCAACCAATGCCAATCTGCGCGCGCACATGGAACGACACGAGCAGGGCGTGGAGCACAGGTGCTCCATATGCGAGAATCAGTTTGCAAACGAATTGGCGCTGCGCGCACATATCAATCAGGAACACCACAAACTGAGTCAATTTGATTGTGAAATATGCCATAAGACGATCGAACCGGATGAGGATCTTGCCATCCACATGCAGAAGCATGCAGCGGTCAAGACACATGTCTGCGAGGTGTGCAATTCGTTTTTCACACAAAAATCGCAATACAATGTGCATATGCGAATGCACACGGGAGAGCGGCCATATCAGTGTCGGATTTGTCATCAGACATTTGCACACTCCAGCGTGCTGAAACTGCACATACGCAAACATACCGGTGAAAAGCCGTTTCGTTGCCTGCTCTGCACGGATGAGGTGGCCTTCTCGCAGCTGGCGCATCTCAAGAATCACATGAAGAAGATACACAAACAGCAGAAGCCCTACATGTGCCATGGCTGCCATGATTTCTTCAAGATCAAAGTGGAGCTGCAGGCGCATGCGGAGCAGTGTAGCAAATGCCAAACAACGGAGGAGCTCAACGATAGTCAGACAGAAGATGCACACACGCTTTCCAGCATTCGCTTCAACATGGCCGTGGTGCTGAAGAAGATTAGCTCGGCGCAGAAACTGCGTCAGCTGGGCTATGAGAAGCGTCTAATTGATAATGTTGTCATTGCCTCACTGAAGTTGGCACAGCGTCCATCGCATGACGATGCGACGCTGACGCCTTTGGCCCGTCTGCGTTTAAATGTGGAGGAGTTTCTCAAGTGGATTGTGCCGACGCACACAATGCAAAAGTTCAGCGAGGAGCTGCTCTCGATCGATACGATACTCGACAAGATTGCGACCATGTACATGAAGCAAAAATAG
Protein Sequence: MVRSRRSLSKEDAASVLTDSGVSLSSPPSAARESSPAATAIKRRKSSLNSLQDLYVDAEPEAEQDSSDAEADADYIQPAPKKSPRKAETSKRKQHVCSHCSKEFGGKTDLLRHMLIHSDERPHKCSECGKCYRQAVNLKNHITTAHEHKKQFACTQCSKSFALKERLRLHMRLHSGEKPYPCALCDKRFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLRAHMERHEQGVEHRCSICENQFANELALRAHINQEHHKLSQFDCEICHKTIEPDEDLAIHMQKHAAVKTHVCEVCNSFFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCLLCTDEVAFSQLAHLKNHMKKIHKQQKPYMCHGCHDFFKIKVELQAHAEQCSKCQTTEELNDSQTEDAHTLSSIRFNMAVVLKKISSAQKLRQLGYEKRLIDNVVIASLKLAQRPSHDDATLTPLARLRLNVEEFLKWIVPTHTMQKFSEELLSIDTILDKIATMYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612236;
90% Identity: iTF_00534722;
80% Identity: -