Basic Information

Insect: Drosophila macrospina
Gene Symbol: -
Assembly: GCA_035042075.1
Location: JAWNLW010000140.1:675334-677553[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.035 2.3 8.8 6.3 1 21 239 259 239 261 0.95

2 12 7.9e-05 0.0051 17.1 1.4 1 23 267 292 267 292 0.95

3 12 0.00024 0.016 15.6 0.8 1 23 299 324 299 324 0.95

4 12 0.00047 0.031 14.7 3.6 1 23 332 354 332 354 0.97

5 12 8.4e-05 0.0055 17.0 0.9 3 23 363 383 361 383 0.98

6 12 0.00011 0.007 16.7 0.1 1 23 389 411 389 411 0.98

7 12 0.17 11 6.7 7.6 1 23 417 440 417 440 0.98

8 12 0.0039 0.26 11.8 3.1 1 23 446 468 446 468 0.97

9 12 0.00011 0.0073 16.6 2.0 1 23 474 496 474 496 0.98

10 12 0.00017 0.011 16.1 0.0 3 23 574 595 573 595 0.96

11 12 0.00047 0.031 14.7 6.8 1 23 601 623 601 623 0.96

12 12 0.0003 0.019 15.3 7.1 1 23 629 651 629 651 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.035	2.3	8.8	6.3	1	21	239	259	239	261	0.95
2	12	7.9e-05	0.0051	17.1	1.4	1	23	267	292	267	292	0.95
3	12	0.00024	0.016	15.6	0.8	1	23	299	324	299	324	0.95
4	12	0.00047	0.031	14.7	3.6	1	23	332	354	332	354	0.97
5	12	8.4e-05	0.0055	17.0	0.9	3	23	363	383	361	383	0.98
6	12	0.00011	0.007	16.7	0.1	1	23	389	411	389	411	0.98
7	12	0.17	11	6.7	7.6	1	23	417	440	417	440	0.98
8	12	0.0039	0.26	11.8	3.1	1	23	446	468	446	468	0.97
9	12	0.00011	0.0073	16.6	2.0	1	23	474	496	474	496	0.98
10	12	0.00017	0.011	16.1	0.0	3	23	574	595	573	595	0.96
11	12	0.00047	0.031	14.7	6.8	1	23	601	623	601	623	0.96
12	12	0.0003	0.019	15.3	7.1	1	23	629	651	629	651	0.98

Sequence Information

Coding Sequence: ATGAATGAGGAACCTCGTGCCTCAACACATACAATATGCCGCACTTGTTTATCCAACTTGCAACATGGTGAAGTCTATGACCTGTTTGTGGTTCCAGGCCTGGCCAAGAAACTGTGTGTCTGCACTTCCCTCTCGGTGGAACATCTGGATGGTTTCCCGAGAAATATCTGCACCAGCTGCTACAATCGCCTTAACGATTTGCACGACTTTCAAAAGCAATGTGTAGACTCTGTGCAAAAGTTCAAAGAGTTGGTGACCAGCAGCTGCTTCATTATCCGAACAATCCCGGATAACGACCCTTCCGTTGTGAATGCTGTTACGCATGATGTAGAGGTGCCTCTCGAGGAAGAGGATTACACGAACTTTGATCCACTGCTGAAtacaaaaatagaaattgataATGAGACAGatgtttttaaaatgattGAAGATGTCGATAGGGAACCCGATGATATAGAGAATTTTGAGAATGTAGATAATAAGGAGGAAGAAGATAATTTTAAGGATATAAATAATGCTTTCAATTACAGCGAAAGCGACTATAGCAATGAGAGCATGGACAGCAGCGAGTCAGATGACGAGGCGCCGCTGTCACGCTTACGAAGTAATAACAGAGCAACAAAGAGCGTAACCAAAAAGAGTGATAAAGATGAGCCTAAAGCAAAATCGAAACGTAAGCGCATTACGGAAGCTGCACGTGAGAGTCATCGGTTATTTAAGTGCCACATTTGTACTCAAAAGTTCAAATTGGCAAAGAGTTATGAGGACCACATGAAATGTCACAATGATCAATTGCCATTTCAGTGTACTGTGCCTACGTGCAAGAGGGGCTTTACGACCTCCACAGGACTGCGTCGTCACATGGAACATGCGCACACGGAACTATGCGAACTTCATCCGTGTACAATCAAAGGTTGCGATGAATCTTTCGCACAAACTCGCATGCTCACACAGCATTTGAGGAAGGTTCACAATATAGCTAAGCCTATAATCCATCCGTGTTCGGAATGCGACAAAGTATTCCGTTGTCCCATGGCGCTCAAGAAACACATGTATAAGCATACTGGCGAAGAGTTGCCATTTGGTTGTACCATATGCCAGAAACGCTTTCGGGTGAGCACCGAACTCCGAGATCATCTTTTAAGACATGCCGGCATCAAGAACTTTGTCTGCCCTTACTGTGGCGTGGGCAGAACAACTAAACAGGAGTTGGACAAGCATATATTAACGCACACGAAGGAAAAGAAGTTTAAGTGTGATCAATGTGATCATACGTCCCACAACAAGCAATGCATGACAAAGCACATCAAGGTGGTGCACATGCAGATCAGGGACTTTGTGTGTAAGTACTGTCAAAAGAGTTTTGGCAGCTCTTATGGGTGTAAAGCCCACGAAAGATTGCATACTCGGGACGACTGCTTCGAGTGTACAATCTGTGGAAGGAAATTTCTTTTTGAGAGTAGACTAAGGAAGCATTTAAGGACTCATGAGAAgcgcaaaaataaacattctGTGGGAAACACAAAAACTGGTGATGAAGCACAGGAGAAATTGACTGAGGCGGTGTCCGTAAACAACGAACCAAAAAATGCTATCAAGCCGAAAGATCCACGTCGAATTGAGATCGTAGATATATCTCAGTTGGCTGGTACCTCCGTGAATCCTATTCCATCGGTATCTGTATCATCCTGGTCCCCACAAAACGAAGGCCAAAATATTTGTCCAGACTGTGGCAAGGGTTTCAATAAGATTGCCGGCTTGAAGCTCCACTACAAAGTTGTTCACGATAAGATCAAAGACTTTGCCTGCCGCTTTTGTCCCAAACGTTTTAGTAAATCTTCGCATCTCCGTCATCATGAGTATACACATACGGGGGAGAAGCCTTACGAGTGCAAATTATGCCATGAGCACTTCAGACATGATGCAACATTAAGAAGGCATATGCAATCACACAACAGACCGCGAAAGGAGCCCAAGGATCCAAAGCCTAAGCCTCAGCCGAAGTCGAATACAGAATGTCCTCCGCAGCCAAGACTACGACTGAATACGGAGCCATCAAAGAATTATGAACAGTATCAGGATCCAAATGCAGAACATGAGGCTGCAACTGCTCAGTTGATAGCCCAACAGCTGGACGAGAGTGAGGCCAAGCAAAGGGCCGAAGCCAAAGTCCGGATGATTCAAGAGGCAGCGTACGAGCAGCTTCAGAAATTGAAGTAA
Protein Sequence: MNEEPRASTHTICRTCLSNLQHGEVYDLFVVPGLAKKLCVCTSLSVEHLDGFPRNICTSCYNRLNDLHDFQKQCVDSVQKFKELVTSSCFIIRTIPDNDPSVVNAVTHDVEVPLEEEDYTNFDPLLNTKIEIDNETDVFKMIEDVDREPDDIENFENVDNKEEEDNFKDINNAFNYSESDYSNESMDSSESDDEAPLSRLRSNNRATKSVTKKSDKDEPKAKSKRKRITEAARESHRLFKCHICTQKFKLAKSYEDHMKCHNDQLPFQCTVPTCKRGFTTSTGLRRHMEHAHTELCELHPCTIKGCDESFAQTRMLTQHLRKVHNIAKPIIHPCSECDKVFRCPMALKKHMYKHTGEELPFGCTICQKRFRVSTELRDHLLRHAGIKNFVCPYCGVGRTTKQELDKHILTHTKEKKFKCDQCDHTSHNKQCMTKHIKVVHMQIRDFVCKYCQKSFGSSYGCKAHERLHTRDDCFECTICGRKFLFESRLRKHLRTHEKRKNKHSVGNTKTGDEAQEKLTEAVSVNNEPKNAIKPKDPRRIEIVDISQLAGTSVNPIPSVSVSSWSPQNEGQNICPDCGKGFNKIAGLKLHYKVVHDKIKDFACRFCPKRFSKSSHLRHHEYTHTGEKPYECKLCHEHFRHDATLRRHMQSHNRPRKEPKDPKPKPQPKSNTECPPQPRLRLNTEPSKNYEQYQDPNAEHEAATAQLIAQQLDESEAKQRAEAKVRMIQEAAYEQLQKLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00510720;
90% Identity: -
80% Identity: -