Basic Information

Insect: Drosophila funebris
Gene Symbol: -
Assembly: GCA_018901825.1
Location: JAEIFK010000122.1:2786989-2789217[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.019 1.3 9.5 5.3 1 21 239 259 239 261 0.95

2 12 0.00034 0.023 15.0 1.7 1 23 267 292 267 292 0.96

3 12 0.00079 0.054 13.9 0.4 1 23 299 324 299 324 0.95

4 12 0.0015 0.1 13.0 3.5 1 23 332 354 332 354 0.97

5 12 7.9e-05 0.0054 17.0 0.9 3 23 363 383 361 383 0.98

6 12 0.00022 0.015 15.6 0.2 1 23 389 411 389 411 0.98

7 12 0.12 8.5 7.0 6.3 1 23 417 440 417 440 0.98

8 12 0.0051 0.34 11.3 2.3 1 23 446 468 446 468 0.97

9 12 0.00013 0.0085 16.4 2.1 1 23 474 496 474 496 0.97

10 12 0.00016 0.011 16.1 0.0 3 23 573 594 572 594 0.96

11 12 0.00042 0.028 14.8 5.7 1 23 600 622 600 622 0.96

12 12 0.0024 0.16 12.4 8.2 1 23 628 650 628 650 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.019	1.3	9.5	5.3	1	21	239	259	239	261	0.95
2	12	0.00034	0.023	15.0	1.7	1	23	267	292	267	292	0.96
3	12	0.00079	0.054	13.9	0.4	1	23	299	324	299	324	0.95
4	12	0.0015	0.1	13.0	3.5	1	23	332	354	332	354	0.97
5	12	7.9e-05	0.0054	17.0	0.9	3	23	363	383	361	383	0.98
6	12	0.00022	0.015	15.6	0.2	1	23	389	411	389	411	0.98
7	12	0.12	8.5	7.0	6.3	1	23	417	440	417	440	0.98
8	12	0.0051	0.34	11.3	2.3	1	23	446	468	446	468	0.97
9	12	0.00013	0.0085	16.4	2.1	1	23	474	496	474	496	0.97
10	12	0.00016	0.011	16.1	0.0	3	23	573	594	572	594	0.96
11	12	0.00042	0.028	14.8	5.7	1	23	600	622	600	622	0.96
12	12	0.0024	0.16	12.4	8.2	1	23	628	650	628	650	0.98

Sequence Information

Coding Sequence: ATGGATGAGGAACCTCGTGCCTCAACACATACAGTATGCCGCACTTGTTTATCCAGATTGCAACATGATGAAGCCTACGACCTGTTTGTTGTCCCCGGCCTGGCCAAGAAATTGTGTGTGTGCACTTCCCTCTCGGTGGAGCATCTGGATGGTTTCCCGAGAAATCTCTGCACCACCTGCTACAAACGCCTTAACGATTTGCATGACTTTCAAAAACAATGCGTGGATTCTGTGCAAAAGTTCAAGGAGTTGGTGACCAGCAGCTGCTTTATTATCCGAACAATCCCCGAGAACGAGCCTGCCGTCGTAAATGCTGCCGTGGCTGATGTAGAGATTCCAATCGAGCAAGTGGATCCCACTACATTCGACCCATTGCTGAGTTCAAAAATAGAAATAGATAATGAGACGGATGTGTTTAAAATGATTGAAGATGTCGATAAGGAACCCGATGAAGTAGAGAACTTGGAGACTGTAGATAATATGGAGGAAGAAGATCATATGGAGAATATAGATAACGCTTTCAATGACAGCGGAAGCGACTATAACCATGAGGGCAAGAACAGCAGCGAGTCTGATGATGAGATGCCGCTGTCACGCTTACGAAGTAAAACCAGACAAACAAAGGCCGAGGCCAAAAAGAGTGATAAAGATGAACCTAAATCAAGACCGAAGCGCAAGCGTATATCGGCTGCTGAACGTAATAGTCGACAGGTATTTGAGTGTCACATTTGTACTCAAAAGTTCAAACTGCCGAAGAGTTATGAAGACCACATGAAATGCCACAATGATCAATTGCCATACCAGTGTACAGTGTCCAAGTGCAAGAGGGGCTTTACGACCATCACAGGACTGCGTCGCCACATGGAACACGCGCACACAGAACTCTGCGATCTTCACCCGTGTACAATCAAAGGATGCGACGCAGCTTTCGCACAAACTCGCATGCTCACAATGCACATGAGGAAGGTGCACAACATAGCAAAGCCTATAATCCATCCTTGTTCTGAATGCGAAAAGGTATTCCGTTGTCCCATGGCATTAAAGAAACATATGTATAAACACACTGGCGAGCAGCTTCCCTTTGGCTGTACTATATGCCAGAAACGCTTTCGGGTAAGCACCGAACTCCGAGATCACCTTTTGAGGCATGCTGGGATCAGAAACTTTGTTTGCCCTTACTGCGGTGTGCGCCGAACAACTAAACAGGAGTTGGACCTCCATATATTAACGCACACGAAGGAAAAGAAGTTCAAATGTGATCAATGTGATCATACTTCCCACAACAAGCAATGCATGGCCAGGCACATCAAGGTGGTACACATGAAGATTAGGGACTTTGTCTGCAAGTACTGTCAAAAGGCCTTTGGCAGCTCTTATGGATGTAAGGCCCACGAAAGATTACATACGCGGGATGACTGTTTCGATTGCACAATCTGTGGAAAGAAATTCCTCTTTGAGAGTAGACTAAGGAAGCATTTAAGGACTCATGAAAAGCGCAAAAATAAATATGCGGCAAACACGCAAACTGCTGATGATGTTCAGGAGAAGTTGGCCGAACCGGTGTCCGTTAAAAGTGTACCAAAAATTCCTGTCAAGCCGACGGATCCACGTCGAATTGAGATTGTGGATATATCTCAATTAGCTGGGACTTCGGTCAATCCCATTCCAACGGTATCTGTCTCATCCTGGTGCCCGCAAAGCGAAGGGCAGAACATTTGTCCAGACTGTGGCAAAGGTTTCAACAAGATTGCCGGCTTAAAGCTCCACTACAAGGTTGTACACGATAAGATCAGAGACTTTGCCTGTCGCTATTGCCCCAAGCGATTCGGCAAGTCTTCACATCTGCGCCATCATGAGTATACTCATACTGGGGAGAAGCCGTACGAGTGCAAATTATGCCATCAGCACTTCAGACATGATGCAACATTAAGAAGGCATATGTTCTCACACAACAGACCGCGAAGGGAGCCAAAGGAGCGAAAGGAACCAAAGGAACCAAAGCCGAAATCGGAGCCAAGACATCACTCGGGGCCAAGACTACGACTGAATACGGAGCCAATGAAGAATTATGAACAGTATCAGGATCCAAATGCAGAGCATGAGGCTGCAACTGCTCAGTTGATAGCCCAACAGATGGACGAGTGTGAGGCCAAACGCAGGGCGGAGGCTAAAGCCCGGGAGATTCAAGAGGCAGCATACGAGCAGCTTGAGAAATTGAAGCAGCCCTAA
Protein Sequence: MDEEPRASTHTVCRTCLSRLQHDEAYDLFVVPGLAKKLCVCTSLSVEHLDGFPRNLCTTCYKRLNDLHDFQKQCVDSVQKFKELVTSSCFIIRTIPENEPAVVNAAVADVEIPIEQVDPTTFDPLLSSKIEIDNETDVFKMIEDVDKEPDEVENLETVDNMEEEDHMENIDNAFNDSGSDYNHEGKNSSESDDEMPLSRLRSKTRQTKAEAKKSDKDEPKSRPKRKRISAAERNSRQVFECHICTQKFKLPKSYEDHMKCHNDQLPYQCTVSKCKRGFTTITGLRRHMEHAHTELCDLHPCTIKGCDAAFAQTRMLTMHMRKVHNIAKPIIHPCSECEKVFRCPMALKKHMYKHTGEQLPFGCTICQKRFRVSTELRDHLLRHAGIRNFVCPYCGVRRTTKQELDLHILTHTKEKKFKCDQCDHTSHNKQCMARHIKVVHMKIRDFVCKYCQKAFGSSYGCKAHERLHTRDDCFDCTICGKKFLFESRLRKHLRTHEKRKNKYAANTQTADDVQEKLAEPVSVKSVPKIPVKPTDPRRIEIVDISQLAGTSVNPIPTVSVSSWCPQSEGQNICPDCGKGFNKIAGLKLHYKVVHDKIRDFACRYCPKRFGKSSHLRHHEYTHTGEKPYECKLCHQHFRHDATLRRHMFSHNRPRREPKERKEPKEPKPKSEPRHHSGPRLRLNTEPMKNYEQYQDPNAEHEAATAQLIAQQMDECEAKRRAEAKAREIQEAAYEQLEKLKQP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537673;
90% Identity: -
80% Identity: -