Basic Information

Insect: Drosophila macrospina
Gene Symbol: -
Assembly: GCA_035042075.1
Location: JAWNLW010000539.1:5701492-5704671[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 2.1e-05 0.0014 18.9 4.7 1 23 167 190 167 190 0.97

2 16 0.0013 0.083 13.3 3.1 1 23 241 264 241 264 0.96

3 16 0.0021 0.14 12.6 3.2 1 23 330 353 330 353 0.96

4 16 0.0072 0.47 10.9 0.4 2 23 404 425 403 425 0.97

5 16 2.9 1.9e+02 2.8 0.7 1 20 538 557 538 559 0.75

6 16 0.02 1.3 9.6 0.6 1 23 568 590 568 590 0.94

7 16 0.00025 0.017 15.5 0.6 1 23 597 620 597 620 0.96

8 16 0.00035 0.023 15.1 1.4 2 23 628 649 627 649 0.96

9 16 0.012 0.77 10.3 0.1 2 21 676 695 675 699 0.88

10 16 0.0016 0.1 13.0 0.7 1 23 736 759 736 759 0.96

11 16 0.37 24 5.6 1.4 1 22 766 787 766 787 0.97

12 16 0.00093 0.06 13.8 0.8 1 23 796 819 796 819 0.97

13 16 1.6e-05 0.001 19.3 0.5 1 23 838 861 838 861 0.97

14 16 0.097 6.3 7.4 0.2 1 23 871 893 871 893 0.94

15 16 2.4e-05 0.0016 18.7 3.3 1 23 899 921 899 921 0.99

16 16 5.1e-05 0.0033 17.7 0.9 1 23 927 949 927 949 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	2.1e-05	0.0014	18.9	4.7	1	23	167	190	167	190	0.97
2	16	0.0013	0.083	13.3	3.1	1	23	241	264	241	264	0.96
3	16	0.0021	0.14	12.6	3.2	1	23	330	353	330	353	0.96
4	16	0.0072	0.47	10.9	0.4	2	23	404	425	403	425	0.97
5	16	2.9	1.9e+02	2.8	0.7	1	20	538	557	538	559	0.75
6	16	0.02	1.3	9.6	0.6	1	23	568	590	568	590	0.94
7	16	0.00025	0.017	15.5	0.6	1	23	597	620	597	620	0.96
8	16	0.00035	0.023	15.1	1.4	2	23	628	649	627	649	0.96
9	16	0.012	0.77	10.3	0.1	2	21	676	695	675	699	0.88
10	16	0.0016	0.1	13.0	0.7	1	23	736	759	736	759	0.96
11	16	0.37	24	5.6	1.4	1	22	766	787	766	787	0.97
12	16	0.00093	0.06	13.8	0.8	1	23	796	819	796	819	0.97
13	16	1.6e-05	0.001	19.3	0.5	1	23	838	861	838	861	0.97
14	16	0.097	6.3	7.4	0.2	1	23	871	893	871	893	0.94
15	16	2.4e-05	0.0016	18.7	3.3	1	23	899	921	899	921	0.99
16	16	5.1e-05	0.0033	17.7	0.9	1	23	927	949	927	949	0.98

Sequence Information

Coding Sequence: ATGACAAGGACATGTAGAATCTGCGGTGGTGCAGATGGACGATATTGGATTGAAACGCCGGTCGATAAATACGCGGAGAAAACATTTAATCAACTTCTGTCAGAGTTAACCAGACTTGAGGTTTCCTTGGATCAAGCTGATAAGCTGCCGCCCTGGTTGTGCCGCAGCTGTGCACAAAGATTGGAAAATGCATATGATTTTGTCCTGCAAGCGCGAGAAACTCATGCGCTCTGGATCCAGAAACTGACAACAGAAACAGCTCTGGATGATGCTGAAAAGGGCACTTCAGAATGTCTACGAGAGACACCAATACAATTGCTGGAGATTGAGGGAGTGACAATCAAAATGGAAGAGTCATCCGAACCTGCAATGCCCCAAGCTGATTCGGTCATTTCAGTTGATCCCCTAATTAAGAAAAACATGGATGATGGTAGCGAGGATGATGACGATGTGCCCTTGAAACAACGCAAAGCACATTACACCAAATTGCCTATGCTGCATAAATGTAACATATGCGATAAATCCTTTAAATATGTAACAAATCTCTTCAGGCACAAGCAGCGAGATCACAGTCCTGTTCAATGCAAACCTAAGATCAAATCAAGTGAGGTGAATGCAAGCTCTGACCACACAGAACCATTCCTACATAATCTTATAAAGAGTTCCATAGTAGCCCGAAGCAGCGCTAATTCCGATTTGGACAATGATGCTGATAATTACTACAAATGTGATCAATGTGACAAGTCATACAAGTACATCATGCTTCTTATCAAGCATAAGCACAAGGCCCATGGCGCCAATCAGTTGCCAGCAGAGCCAAGGCCAATTCGAAGAAGCGAATCGAATTCAGAACCATCATCTCAAGTTAGAACAACTCAGCGACAGCGTTCAAAGCCGCCCAGCACAGATTCCTTGGTGCACAGTCTAATCAAAGAGGTCAAAACACCTGAAGAGGACGATCCAGATAGCACAAGTGCTGACAATTACTACAAGTGCGATCAATGTGAAAAGTCTTACAAATATATAGTGAGTCTCatcaagcacaagcacaaagaGCACAATACATACAAAGATTCCGATGAAGATGAGGACGATGGCATATCCACATATGCTTCGGCGACACCTTCAATGTCAAAGCCTTCTCGCATCGATCGGAGGGTAAAGGGATTCGACTTACATCGCTGCAAGCCAAATGGTTCCAAGGAGATTCAATGCATGATTTGCCTGCGAAGATTTGTTAAAATGAGAGAGCTGCGCGATCATCTCAGAGCACACCCCAGAGACTTTACATTCGACGCTCACGGCGAGCCCATTGAACGTATTGCTGAAGGCTTTTACAAGACCGCCGTGGAATCCTCAGCTGTAGGATTGAAAATGCGAATTTTAAATGATCTCAGGATTGGCATGTATGGCCGCTATTACTCCATAACAAATGAGGCGCGTTACGAGATGAATCTGGACAGCTCGGACACGGATAGCGATGGTGAGGCGGGAGTTGTTGAGCGACGAAGTTATGCCTGCGAACTATGTGATTCGCCCTCCGCCGTTTGGCCACGTAAATTTCAGTTGCATGAGCATCACCGACAGCAACATACTTGGTTGGAGGCGCCCTACGTCTGTCAGCGTTGTGATTCACGTTTCTTAAGCGCTCAACTACTCGACCATCACACGCAAAAACTCTGTCAGAATACCCTTAAGCGTTTCATGTGCGACAAGTGTCCGCAGCGATTCTTCTGGCGCCGTAATCTGCGTGCACATCTTGTAGAGCATAAAAACAAGCAAGAGAATTACCCATGTGATCAGTGCTCACGTAGCTTTCAGGACAAAAGCGCCGTGACGAAACACAAACTCATGCTTCATGATGTTAGCAACGAACTGATACCTTGCCGATGGTGCACGCGGACATTCTATCGTCCTGCCCTACTGCATAAGCATGTGAAGCGACACGGCTTCAATGGAGAAGATCTCCCCTTGGCTGAGACACTGCTTGCAGATGCCGCGAAGCCATCTGGTCCGAAAACGATCGTTTGCAAACTATGCGATATGCAGTTCGTTAGCATTGCCGATCTGCGACGGCACAATTCAATGCAAGCGCATAGCGAAGAGGCTTGCAATTACATGATAAGCACAGAGAATGGATTTGAGTTGCAACTGGAGGAGACAGACGATAGCGATGATGAGACTACTGGTTCTGCTGGCAGATCCTACAGGTGTGATCTCTGCGAAATGGCCTTCCAGCGTCGTAGGGACTTGAGCGAGCATCAGTATTCCTTGCACAACTTTGATAAATTACCCTATTCCTGTGAGCATTGCATCTTCAAGACGGTTGACAAAACCATGCTGGCCCATCATTTACGCACGCAGTGCTTAAACCAGGagaagaaatttaaatgtacGCGTTGTGGCTACAAATTCATGTGGAGTGAAAACCTGGAACAACATATGGCCAGCCAACACTCTAAATCGACCAATCATATGGCTGTTGCGACCAAGCGAAGTCGACGCTTTAGATACCAGTGTCCGCATTGCTGGCGCTCCTTTGTTGTCCAGCCCAGTTTGGACAAGCACATACGGGACATGCATGTGGCCAAAAAAAATCCCGGCAAGAAGTATCTCTGCTCATTATGCGGGCTGGAGTCGCTCACCCCCAACAAGCTTAGCATCCACATGCGACGTCATAATGGCGAGAAGCCCTTCAAATGCGATCTATGCGACATGTCCTTTACAGTCCACTACGAGCTAAAAGTGCATCGACGAAAGCATACGGGCGAGCGACCCTATCAATGTACTTTTTGTGCCAAGGATTTCGCACGACCGGACAAACTAAGGCGACATGTGTACATGCACAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRYWIETPVDKYAEKTFNQLLSELTRLEVSLDQADKLPPWLCRSCAQRLENAYDFVLQARETHALWIQKLTTETALDDAEKGTSECLRETPIQLLEIEGVTIKMEESSEPAMPQADSVISVDPLIKKNMDDGSEDDDDVPLKQRKAHYTKLPMLHKCNICDKSFKYVTNLFRHKQRDHSPVQCKPKIKSSEVNASSDHTEPFLHNLIKSSIVARSSANSDLDNDADNYYKCDQCDKSYKYIMLLIKHKHKAHGANQLPAEPRPIRRSESNSEPSSQVRTTQRQRSKPPSTDSLVHSLIKEVKTPEEDDPDSTSADNYYKCDQCEKSYKYIVSLIKHKHKEHNTYKDSDEDEDDGISTYASATPSMSKPSRIDRRVKGFDLHRCKPNGSKEIQCMICLRRFVKMRELRDHLRAHPRDFTFDAHGEPIERIAEGFYKTAVESSAVGLKMRILNDLRIGMYGRYYSITNEARYEMNLDSSDTDSDGEAGVVERRSYACELCDSPSAVWPRKFQLHEHHRQQHTWLEAPYVCQRCDSRFLSAQLLDHHTQKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQENYPCDQCSRSFQDKSAVTKHKLMLHDVSNELIPCRWCTRTFYRPALLHKHVKRHGFNGEDLPLAETLLADAAKPSGPKTIVCKLCDMQFVSIADLRRHNSMQAHSEEACNYMISTENGFELQLEETDDSDDETTGSAGRSYRCDLCEMAFQRRRDLSEHQYSLHNFDKLPYSCEHCIFKTVDKTMLAHHLRTQCLNQEKKFKCTRCGYKFMWSENLEQHMASQHSKSTNHMAVATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00806138;
90% Identity: iTF_00528986;
80% Identity: -