Basic Information

Insect: Drosophila macrospina
Gene Symbol: -
Assembly: GCA_035042075.1
Location: JAWNLW010000301.1:4385209-4387286[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.2e-07 2.1e-05 24.7 1.1 1 23 83 105 83 105 0.99

2 15 0.00084 0.055 13.9 3.1 1 23 111 133 111 133 0.96

3 15 0.00024 0.016 15.6 2.6 1 23 139 161 139 161 0.99

4 15 4.3e-06 0.00028 21.1 0.1 2 23 185 206 184 206 0.97

5 15 8.4e-05 0.0055 17.0 3.6 1 23 212 234 212 234 0.96

6 15 0.039 2.5 8.7 0.8 1 15 240 254 240 254 0.94

7 15 0.0037 0.24 11.8 0.7 1 20 366 385 366 386 0.93

8 15 2.3e-07 1.5e-05 25.1 3.0 1 23 400 422 400 422 0.99

9 15 4.8e-08 3.1e-06 27.2 1.0 1 23 428 450 428 450 0.99

10 15 1e-05 0.00067 19.9 3.9 1 23 456 478 456 478 0.98

11 15 3.1e-07 2e-05 24.7 3.3 1 23 488 510 488 510 0.98

12 15 6.4e-06 0.00042 20.6 6.8 1 23 516 538 516 538 0.99

13 15 2e-07 1.3e-05 25.3 5.2 1 23 544 566 544 566 0.99

14 15 0.0016 0.1 13.0 3.3 2 23 573 594 572 594 0.97

15 15 5.1e-07 3.3e-05 24.0 3.0 1 23 600 622 600 622 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.2e-07	2.1e-05	24.7	1.1	1	23	83	105	83	105	0.99
2	15	0.00084	0.055	13.9	3.1	1	23	111	133	111	133	0.96
3	15	0.00024	0.016	15.6	2.6	1	23	139	161	139	161	0.99
4	15	4.3e-06	0.00028	21.1	0.1	2	23	185	206	184	206	0.97
5	15	8.4e-05	0.0055	17.0	3.6	1	23	212	234	212	234	0.96
6	15	0.039	2.5	8.7	0.8	1	15	240	254	240	254	0.94
7	15	0.0037	0.24	11.8	0.7	1	20	366	385	366	386	0.93
8	15	2.3e-07	1.5e-05	25.1	3.0	1	23	400	422	400	422	0.99
9	15	4.8e-08	3.1e-06	27.2	1.0	1	23	428	450	428	450	0.99
10	15	1e-05	0.00067	19.9	3.9	1	23	456	478	456	478	0.98
11	15	3.1e-07	2e-05	24.7	3.3	1	23	488	510	488	510	0.98
12	15	6.4e-06	0.00042	20.6	6.8	1	23	516	538	516	538	0.99
13	15	2e-07	1.3e-05	25.3	5.2	1	23	544	566	544	566	0.99
14	15	0.0016	0.1	13.0	3.3	2	23	573	594	572	594	0.97
15	15	5.1e-07	3.3e-05	24.0	3.0	1	23	600	622	600	622	0.98

Sequence Information

Coding Sequence: ATGAGTGCAACCATAGACATAAGCTGCGTAAAGATTGAGCCAGAGCAAGACGAGGAGACGATAAGGGAAACGGACTTGGGCGTGCTCAAAACTGAGAATGATTTGGAGATTGATATAGGACCAATCAAGATAGAGCCGGAAACGTCCATAGAGTGTGAGACTCCCAGTCCCAGCAGAAAGACTATAAGGCAGCCGAAGAAGCTGccttcagttgttgctgctacagcGAAAAGTTCTACGAGTCACTATCAGTGTCCCCACTGTCCGCGGCACTTTGAGAGAAGCGATGAACTCGAAATACACATTCAGATTCACAGCAAGAATCTGCTCTACAAGTGTTCCTACTGCCCAAATAGTTTCTCCCATAAATCCATATTTACGGCGCACATGTTTGGACATACTGGGAAATTTCCCTACCAATGCTCCGATTGTCCGCAAGGATTTCTCAAGAACTGCGATCTAAAGAAACACATGCGACTGCATGTGGACAAACGTCCAGCCAAGTGTTCATTGTGTCCCAGGAAATGCACGCATAAAGGCATTTATCCTCTACAGTGTCCACAGTGTCCACGTGGTTTCAAGAACAGCGAGGAACTAGAGATACACCTGCAGATTCATAGCGACAAACTTCCACACAAGTGCTCTTACTGCCCAATTAGCTTTGCGCATAAATCCAACTATCTGTCGCATATTTACGAGCACACGGGTGAATTCCCTTACAAATGTCATGAGTGTCCTCAGGGCTTCATGAGGAGATCTCACGGCAGCGCACAAATAGTTCGCAAAGACTTAATTAAGAATTCCGAAAGGACAGAAACCATCTTGGACGCCAATTGCATCAAAAATGAGAAAGAGGAGGAACCGCCACACAGTGCATCCAGCTTGCAGACTGCTCCAGTGAAAGCCAAACCTAAAGGAAATGCAAAGGATATTAAGGTGGCCGCCGTTAAACAGgaaaaagacaaacaacaaagtgcCTTGGCTAAGTTGGATGCTGAAAAGTCTCTAGTTGTAATCAAAACCGAATCAGTTGAGAGTACAGAGCAATCTCAGCCAGAGAAGCAGCCTTTAATGAACGCTAGCAAGGATAAGTCCTACAGGTGCAAGATCTGCAATAAGGAATTCATGGACATGCAAGATTTGCACTTGCATGAGAAATGCTATACACACTCCAATAGGCAGCTGGGTATCCGGCCGTATAAATGTGATTACTGCTCCATGACATTTACACAGACATACAATCTGACGGTACATATGCGCAAGCATACGGGTGAACGTCCATATCAATGTCCACACTGTCCGCGGACTTTCATACAGAATTCGGGACTGAAGGTGCACATTCGACAGCATTCCGGCGAAAGGCCTTATCAATGTGCCCATTGTCCACGTACATTTGCCAATCATTCGAATCGAACGAAACACATGCTAATCCACAGCAAGGAGTTGGCCAGAGATCATCCCTACAAGTGCCCACACTGCCCCAAAACGTTTGCACAAAACTCTCATTTCATAACGCATGTCCGTGGCCATACGGGTGAACGTCCGTATCAATGTACCCACTGCTCCAAGGGCTTTAAGGTCAGTCACGATTTGAAGAAACACCAGCGCAGCCATACCGGAGAGCGTCCCTACAAGTGTCCTCATTGCCCGAAGACCTTTGCCCAAAACTCACATTATCATGCGCATATTCGGGTGCATTCTGATGAGCGGCCCCTAGAGTGTCCCCACTGTCCGTGCACCTTTCTCAAGAGCTATAATCTGAAAGTTCATCTCTACACCCATACGGGTGAACGGCCCTTCAAGTGTCCACACTGCCCCAAAACATTTACTCAGAACTCCAGTCGCAAGGTGCACATTCGTGAGCATTTAGCGAGCAAAggaaattag
Protein Sequence: MSATIDISCVKIEPEQDEETIRETDLGVLKTENDLEIDIGPIKIEPETSIECETPSPSRKTIRQPKKLPSVVAATAKSSTSHYQCPHCPRHFERSDELEIHIQIHSKNLLYKCSYCPNSFSHKSIFTAHMFGHTGKFPYQCSDCPQGFLKNCDLKKHMRLHVDKRPAKCSLCPRKCTHKGIYPLQCPQCPRGFKNSEELEIHLQIHSDKLPHKCSYCPISFAHKSNYLSHIYEHTGEFPYKCHECPQGFMRRSHGSAQIVRKDLIKNSERTETILDANCIKNEKEEEPPHSASSLQTAPVKAKPKGNAKDIKVAAVKQEKDKQQSALAKLDAEKSLVVIKTESVESTEQSQPEKQPLMNASKDKSYRCKICNKEFMDMQDLHLHEKCYTHSNRQLGIRPYKCDYCSMTFTQTYNLTVHMRKHTGERPYQCPHCPRTFIQNSGLKVHIRQHSGERPYQCAHCPRTFANHSNRTKHMLIHSKELARDHPYKCPHCPKTFAQNSHFITHVRGHTGERPYQCTHCSKGFKVSHDLKKHQRSHTGERPYKCPHCPKTFAQNSHYHAHIRVHSDERPLECPHCPCTFLKSYNLKVHLYTHTGERPFKCPHCPKTFTQNSSRKVHIREHLASKGN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00510676;
90% Identity: -
80% Identity: -