Basic Information

Insect: Drosophila funebris
Gene Symbol: -
Assembly: GCA_018901825.1
Location: JAEIFK010000425.1:8514315-8516336[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.8e-06 0.00012 22.2 2.5 1 23 73 95 73 95 0.98

2 15 0.0017 0.11 12.9 4.0 1 23 101 123 101 123 0.96

3 15 5e-05 0.0034 17.7 1.7 1 23 129 151 129 151 0.99

4 15 6.2e-05 0.0042 17.4 0.1 2 23 175 196 174 196 0.97

5 15 7.5e-05 0.0051 17.1 3.8 1 23 202 224 202 224 0.96

6 15 4.5e-06 0.00031 20.9 1.9 1 23 230 252 230 252 0.99

7 15 0.0021 0.14 12.6 0.2 1 20 373 392 373 393 0.94

8 15 3.9e-07 2.6e-05 24.3 3.7 1 23 407 429 407 429 0.98

9 15 4.5e-08 3.1e-06 27.2 1.0 1 23 435 457 435 457 0.99

10 15 9.8e-06 0.00066 19.9 3.9 1 23 463 485 463 485 0.98

11 15 6.4e-07 4.3e-05 23.6 3.2 1 23 495 517 495 517 0.98

12 15 6.4e-06 0.00043 20.5 6.3 1 23 523 545 523 545 0.99

13 15 1.9e-07 1.3e-05 25.3 4.0 1 23 551 573 551 573 0.99

14 15 0.0032 0.21 12.0 6.4 2 23 580 601 579 601 0.97

15 15 1.6e-05 0.0011 19.2 4.7 1 23 607 629 607 629 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.8e-06	0.00012	22.2	2.5	1	23	73	95	73	95	0.98
2	15	0.0017	0.11	12.9	4.0	1	23	101	123	101	123	0.96
3	15	5e-05	0.0034	17.7	1.7	1	23	129	151	129	151	0.99
4	15	6.2e-05	0.0042	17.4	0.1	2	23	175	196	174	196	0.97
5	15	7.5e-05	0.0051	17.1	3.8	1	23	202	224	202	224	0.96
6	15	4.5e-06	0.00031	20.9	1.9	1	23	230	252	230	252	0.99
7	15	0.0021	0.14	12.6	0.2	1	20	373	392	373	393	0.94
8	15	3.9e-07	2.6e-05	24.3	3.7	1	23	407	429	407	429	0.98
9	15	4.5e-08	3.1e-06	27.2	1.0	1	23	435	457	435	457	0.99
10	15	9.8e-06	0.00066	19.9	3.9	1	23	463	485	463	485	0.98
11	15	6.4e-07	4.3e-05	23.6	3.2	1	23	495	517	495	517	0.98
12	15	6.4e-06	0.00043	20.5	6.3	1	23	523	545	523	545	0.99
13	15	1.9e-07	1.3e-05	25.3	4.0	1	23	551	573	551	573	0.99
14	15	0.0032	0.21	12.0	6.4	2	23	580	601	579	601	0.97
15	15	1.6e-05	0.0011	19.2	4.7	1	23	607	629	607	629	0.98

Sequence Information

Coding Sequence: ATGAGTGCAAAAATAGACATAAGCTGCGTGAAGATTGAGCCAGAGCAAGATGAGGAAACGGACTTGAGTGTGCTAAAAACTGAGAATGACTTGGAGATTGACATAGGACCAATCAAGATAGAGCCGGGAACGTTCACAGAGTGTGAGACCCTCAGCCAGCAGCAGAAGAAGCAGCCTGCACCTGTTGCTGCTGTAGCGAAAAGTTCCACGAGTGTCCATCAGTGTCCCCACTGTCCGCGGCACTTTGAGAGAAGCGATGAACTCGAAATACACATTCAGATACACAGCAACAATCTGATGTACAAGTGTTCTTACTGCCCAAATAGTTTCTCTCACAAGTCCATATTTACGACACACATGTACGGACATACTGGCAAGTTTCCCTACCAATGTCCTGATTGTCCGCAAGGATTTCTGAAGAACTGCGATCTAAAGAAACACATGCGACTGCATGTCGACAAACGTCCACCCAAGTGTTCATCATGCCCTAGGAAATGCACGCATAAATGCATTTATCCTCTGCAGTGTCCACAGTGTCCACGTGGCTTCATGAAGAGCGACGAACTAGAGATCCATCTACAGATACACAGCGACAAGCTTCCACACAAGTGTACTTACTGTCCGATTAGTTTTGCACATAAATCGAATTACCTGTCGCATATATACGAGCACACAGGTGAATTTCCTTACAAATGCCATGAGTGTCCTCAGGGCTTCATGAGGAGATATGAGCTAATGAAGCATCTACAAATTCATTGTGATAAGCGAGTCGTAGTGCCACGTCTAAGCTCAAGGCAACGCACAAATAGCTCACAAACAGAGTTAAAAAGGAATCCGAAAAAGACAGAAACCAACTTGGAGAACAACAACAGCATCAAAAAGGAGAAGGAGGAGGAACCGCTACGTAGTGGATCCAGCTTGCAGATGGCTTCACTAAAACCCAAAGCTAAAGGGAATGCAAAGGATGTAAAGGTGGCCACCGTTAAGCTGGAACAAGGCTTAGCAAAGTTGGATGTTGAAAAGTCGCTGGTTGTCATCAAAACCGAGCCAGCTGAGAGAACTGAGCCAGCCCAGGCAGAGGAGCAGCCGTTAACGAACGCCAGCAAGCATAAATCCTACATGTGCAAGATCTGCAATAAGGAATTCATGGACATGCAAGATTTACGCTTGCATGAGAAATGCTATACACACTCAAATAGACAGTTGGGCATACGGCCGCATAAATGTGATTACTGCCCGATGACTTTCACACAGACATACAATCTGACGGTGCATATGCGCAAACATACGGGCGAACGTCCATATCAATGTCCACACTGTCCGCGGACTTTCATACAGAATTCGGGACTGAAGGTGCACATTCGACAACATTCTGGTGAAAGGCCTTATCAATGCGCCCATTGTCCACGCACATTTGCCAATCATTCGAATCGAACGAAACACATGCTTATCCACAGCTCAGAGTTGGAACGAGATCATCCCTACAAGTGTCCACATTGTCCCAGAACTTTTGCACAAAACTCGCATTTCATAACGCATGTACGTGGCCACACGGGTGAACGTCCCTATCAATGTACACACTGCTCCAAGGGCTTTAAAGTCAGTCACGATTTGAAGAAGCATCTGCGCAGCCATACCGGAGAGCGTCCCTACAAGTGTCCCCACTGCCCGAAAGCCTTTGCTCAAAATTCACATTATCATGCGCACATTCGTGTACATTCTAGTGAGCGGCCGCTGCAGTGTCCCCACTGTCCGTGCACCTTTCTCAAGAGCTACAATCTGAAAGTTCATCTCTGCACCCATACAGGAGAACGTCCCTTTAAGTGCCCACATTGCCCCAAAACATTTACTCAGAACTCCAGTCACAAGGTGCACATTCGTGAGCATCAAGCGTGCAAATGA
Protein Sequence: MSAKIDISCVKIEPEQDEETDLSVLKTENDLEIDIGPIKIEPGTFTECETLSQQQKKQPAPVAAVAKSSTSVHQCPHCPRHFERSDELEIHIQIHSNNLMYKCSYCPNSFSHKSIFTTHMYGHTGKFPYQCPDCPQGFLKNCDLKKHMRLHVDKRPPKCSSCPRKCTHKCIYPLQCPQCPRGFMKSDELEIHLQIHSDKLPHKCTYCPISFAHKSNYLSHIYEHTGEFPYKCHECPQGFMRRYELMKHLQIHCDKRVVVPRLSSRQRTNSSQTELKRNPKKTETNLENNNSIKKEKEEEPLRSGSSLQMASLKPKAKGNAKDVKVATVKLEQGLAKLDVEKSLVVIKTEPAERTEPAQAEEQPLTNASKHKSYMCKICNKEFMDMQDLRLHEKCYTHSNRQLGIRPHKCDYCPMTFTQTYNLTVHMRKHTGERPYQCPHCPRTFIQNSGLKVHIRQHSGERPYQCAHCPRTFANHSNRTKHMLIHSSELERDHPYKCPHCPRTFAQNSHFITHVRGHTGERPYQCTHCSKGFKVSHDLKKHLRSHTGERPYKCPHCPKAFAQNSHYHAHIRVHSSERPLQCPHCPCTFLKSYNLKVHLCTHTGERPFKCPHCPKTFTQNSSHKVHIREHQACK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537643;
90% Identity: -
80% Identity: -