Dmac008440.1
Basic Information
- Insect
- Drosophila macrospina
- Gene Symbol
- Bro
- Assembly
- GCA_035042075.1
- Location
- JAWNLW010000454.1:5337714-5338391[+]
Transcription Factor Domain
- TF Family
- CBF
- Domain
- CBF_beta domain
- PFAM
- PF02312
- TF Group
- Beta-Scaffold Factors
- Description
- Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 2.5e-72 2.2e-68 229.1 0.5 1 153 38 186 38 197 0.96
Sequence Information
- Coding Sequence
- atgcatcatcatcaacagaaTCTTGGAGATGCGGCTGCATTAACGGGCATGATGCCACCCTACGAAACGATGGCGATGTATGAGCCACCGAAACCACGCTTCATCTTCAAAATGCCACGCGTTGTGCCGGATCAAAAGTCCAAATTCGAAACTGATGAGCTCTTTCGCCGCCTGAGCCGAGAGAGCGAGGTGCGCTATACGGGCTATAGGGAACGAGCCATAGATGAACGACGGATGAGATTTGTGACAGATTGCCGCAAAGGCTATGCAGAGCTCTCGTTTGTTGCCTCTGGCACCAATCTGCAGCTCTATTTCAATGCCAATCACAATCCCTATGCTCAGGAACAGGAGTGTGACTTTGAGAAGGAGCGCAGTAAAGTGCATCTGAGGTCTAACTTCATTTTGAACGGCGTCTGCGTGCGTTTCCGTGGCTGGGTGGATCTGGATCGATTAGATGGCGTCGCCTGCTTGGAGTATGACGAAGGACGTGCCCTGCTGGAGGATGCACAGTTGTGCGAGCAAATTGATAATCATAATCAGCGCATGGCCGAATCGAAACGCATCTATGCGCATACGCCTCCACAGGATGCAATGCGTCGAACTGGACAAGGAATGGCACcggcaatgggaatgggaacggCACCAGCAACGATTACTGGACCGCCAATGGGCTGGTGA
- Protein Sequence
- MHHHQQNLGDAAALTGMMPPYETMAMYEPPKPRFIFKMPRVVPDQKSKFETDELFRRLSRESEVRYTGYRERAIDERRMRFVTDCRKGYAELSFVASGTNLQLYFNANHNPYAQEQECDFEKERSKVHLRSNFILNGVCVRFRGWVDLDRLDGVACLEYDEGRALLEDAQLCEQIDNHNQRMAESKRIYAHTPPQDAMRRTGQGMAPAMGMGTAPATITGPPMGW
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00584939;
- 90% Identity
- iTF_00557665;
- 80% Identity
- -