Basic Information

Insect: Drosophila lowei
Gene Symbol: prg
Assembly: GCA_008121275.1
Location: CM017779.1:13817707-13819514[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.15 11 6.6 0.6 1 23 223 246 223 246 0.94

2 9 0.002 0.15 12.4 1.0 1 23 252 275 252 275 0.97

3 9 8.1e-06 0.0006 20.0 0.3 1 23 281 303 281 303 0.97

4 9 6.4e-09 4.8e-07 29.7 2.7 1 23 309 331 309 331 0.99

5 9 0.00015 0.011 16.0 0.4 1 23 337 359 337 359 0.98

6 9 0.00039 0.029 14.7 2.6 1 23 365 387 365 387 0.98

7 9 8e-06 0.0006 20.0 0.6 1 23 437 459 437 459 0.96

8 9 2.6e-05 0.0019 18.4 0.3 3 23 466 487 464 487 0.92

9 9 0.077 5.7 7.5 0.6 1 23 491 513 491 513 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.15	11	6.6	0.6	1	23	223	246	223	246	0.94
2	9	0.002	0.15	12.4	1.0	1	23	252	275	252	275	0.97
3	9	8.1e-06	0.0006	20.0	0.3	1	23	281	303	281	303	0.97
4	9	6.4e-09	4.8e-07	29.7	2.7	1	23	309	331	309	331	0.99
5	9	0.00015	0.011	16.0	0.4	1	23	337	359	337	359	0.98
6	9	0.00039	0.029	14.7	2.6	1	23	365	387	365	387	0.98
7	9	8e-06	0.0006	20.0	0.6	1	23	437	459	437	459	0.96
8	9	2.6e-05	0.0019	18.4	0.3	3	23	466	487	464	487	0.92
9	9	0.077	5.7	7.5	0.6	1	23	491	513	491	513	0.98

Sequence Information

Coding Sequence: ATGTATATTACACAGATGGAAACTCCAATGGCCCCGCCAAACGAGAGGCCAAACACTGCCAGCTCGTGCCGCCTGTGCCATCGGCCGGCGTCGACCGAGACCACGCCAAACATTTTCAACGATCGCGAGGGTTTCTGGGATGGCGACAAATTCTGCATTGCCGATGTCTGCCAGAGCGTATGGGGAGTTCAGTACGATCGCCATGAGTACTTGCCGGAGCAGATATGCTCTGATTGCTTGGAAGTGCTGGAGGATTTCTATAAACAACGGCGGGGAATGAAGCAGCGGGAAGCCGCCTTGCAGGAGCAACTGAAGGAGATAATTAAAAAGGATCCCAAGTATCGACCTGGCTTGAACGGAAATCCTGGTGTATTTGAGCCCGGAGACGATTGCGAAATTGTGGAAGTGGATCCGGATAAGGTTGCGGAGACGAGCGATGATGAGATGGGCTCCGATGAAGAGAACGAGAATGcagaggacgaggaggaagaggaggagttCGAGGACTTCGAGGAAGATGAAGCAGATACGACGAATGCAGAAGATGCTGacatgcccatgcccctggGCATAGATGCTGCTCAAATGGCGCAAATGTCGGTGGAAATGAAGTTAGAGCAGCCCAGTGCTGTATCCAACACTGGAGGACCACGTCCCAAGACCGCTTTTCTGTGTCAGTACTGCGACTTGGGCTATACGCTTCCAGCTGAATGCCAGCAGCATGAGAGAACCGCCCATGATCCCCATGCTCCATACTGTTGCACATTTTGCAGTTTGCTTTTCATCACGCGAGCCGCCTTAATTGCCCATATCAAGTCGCAGCACGATATGGATCGTCCCTACGTGTGTGCCCAGTGCAGGAAGGGATTTGTGCGCCGCTCCGACCTCAAGAAGCACGCCATCGTCCATACCGGCGTGCGGCCCTACACCTGCACTGTCTGCACAAAGAGCTTCTCCCGAAACACCAATCTGACAAAGCATATGCGGATTCACAGCGGAGAGAAGCCGTTCGTGTGCCAGCAATGTCCACGCTCCTTCCAGACCGCCCAGGAGATGACAAACCACGCGCGTTTGCATTCCGGCGCCAGACCCTTCCAGTGCAACCGCTGTCCGTTCTCCTCATCGCGCAAGGACAAGCTTGTTGCCCATCAGCATATGCACACTAAGCGCGACGTTGAGCAGatcttgcagcagcagcaacaaaacgCCCTGCATCCACCGACCCCGGAGGAGCTGGCGCAACTACAGCACGAGCTGACGCAACAGTTGAAGCCGAAGCCAATAACTCCACAGAAGCCAGGACGAAGCTTCCGTTGCGACGTCTGCGACAGGGTCTTCCAACGGGAGCGCGATCTTCAGCGTCATCGTGCGCTTCATCTGGACACGCTGCTGGCCTGTAAGGTATGCAATCTAGTCTTCAATCGGCGCGAACAGCTGCAGCGTCACACACTGGAGGCTCACGGTCCTACCTATACGTGCGCCATTTGCTGCATTACCTTTTTGCAGCAGATTGAGCTGGAGAACCACTTGAAGGTCCATCAGCTGCAGCACAAGGTGGCTCAAAGCACCCAGCAGGCCATGATTGCTGCTGCGACTATGCCCCACAAAATTGTTGAACCGACAGCGGTGCCCAAAATGCTCCCAGTGCCACAGGTGCCGCTACAGATGCGTCCTTCAGCCGCAGAGCTCAACTTCTACAGCAACATGATTCCCACCATGAACCTGGGCTTCTATAGCGAAACGCGGCCCGAGGAATAA
Protein Sequence: MYITQMETPMAPPNERPNTASSCRLCHRPASTETTPNIFNDREGFWDGDKFCIADVCQSVWGVQYDRHEYLPEQICSDCLEVLEDFYKQRRGMKQREAALQEQLKEIIKKDPKYRPGLNGNPGVFEPGDDCEIVEVDPDKVAETSDDEMGSDEENENAEDEEEEEEFEDFEEDEADTTNAEDADMPMPLGIDAAQMAQMSVEMKLEQPSAVSNTGGPRPKTAFLCQYCDLGYTLPAECQQHERTAHDPHAPYCCTFCSLLFITRAALIAHIKSQHDMDRPYVCAQCRKGFVRRSDLKKHAIVHTGVRPYTCTVCTKSFSRNTNLTKHMRIHSGEKPFVCQQCPRSFQTAQEMTNHARLHSGARPFQCNRCPFSSSRKDKLVAHQHMHTKRDVEQILQQQQQNALHPPTPEELAQLQHELTQQLKPKPITPQKPGRSFRCDVCDRVFQRERDLQRHRALHLDTLLACKVCNLVFNRREQLQRHTLEAHGPTYTCAICCITFLQQIELENHLKVHQLQHKVAQSTQQAMIAAATMPHKIVEPTAVPKMLPVPQVPLQMRPSAAELNFYSNMIPTMNLGFYSETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487472;
90% Identity: iTF_00517902; iTF_00580942; iTF_00575016; iTF_00580938; iTF_00487472; iTF_00471826; iTF_00473987; iTF_00481033;
80% Identity: -