Basic Information

Insect: Drosophila helvetica
Gene Symbol: prg
Assembly: GCA_963969585.1
Location: OZ018402.1:55466955-55468739[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.27 26 6.0 1.0 1 23 211 234 211 234 0.95

2 9 0.0012 0.11 13.4 1.3 1 23 240 263 240 263 0.97

3 9 9.4e-06 0.0009 20.0 0.3 1 23 269 291 269 291 0.97

4 9 5.5e-09 5.2e-07 30.2 2.6 1 23 297 319 297 319 0.99

5 9 0.00017 0.017 16.0 0.4 1 23 325 347 325 347 0.98

6 9 6.3e-05 0.006 17.4 1.0 1 23 353 375 353 375 0.99

7 9 9.3e-06 0.00089 20.0 0.6 1 23 425 447 425 447 0.96

8 9 5.6e-05 0.0053 17.6 0.2 3 23 454 475 452 475 0.89

9 9 0.089 8.5 7.5 0.6 1 23 479 501 479 501 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.27	26	6.0	1.0	1	23	211	234	211	234	0.95
2	9	0.0012	0.11	13.4	1.3	1	23	240	263	240	263	0.97
3	9	9.4e-06	0.0009	20.0	0.3	1	23	269	291	269	291	0.97
4	9	5.5e-09	5.2e-07	30.2	2.6	1	23	297	319	297	319	0.99
5	9	0.00017	0.017	16.0	0.4	1	23	325	347	325	347	0.98
6	9	6.3e-05	0.006	17.4	1.0	1	23	353	375	353	375	0.99
7	9	9.3e-06	0.00089	20.0	0.6	1	23	425	447	425	447	0.96
8	9	5.6e-05	0.0053	17.6	0.2	3	23	454	475	452	475	0.89
9	9	0.089	8.5	7.5	0.6	1	23	479	501	479	501	0.98

Sequence Information

Coding Sequence: ATGCACATCACACAGATGGAAGCTCCACAGCCCACGCCAAACGAGAGGCCGAACATGGCCAGTTCGTGCCGCCTGTGCCATCGGCCGGCATCGACCGCCACCACGCCAAACATTTTCACGGAGGGTTTCTGTGATGATGACAAATTCTGCATTGCCGATGTCTGCCAGAGCGTATGGGGAGTCCAGTACGACCGACATGAGTATTTACCGGAGCAGATATGCTCCGATTGCTTGGAAGTATTGGACGATTTCTATAAGCAGCGGAGGGGAATGAAGCAGCGGGAAGCCGCCTTGCAGGAGCAACTGAAGGAGATCATTAAAAAGGATCCCAAGTATCGGCCCGGCTTAAACGGAAATCCCGGTGTATTTGAGCCCGGAGATGATTGTGAAATTGAGGAAGTGGATCCGGATAAGGTTGCGGAGACGAGCGATGATGAAATGGGCTCCGATGAAGAAAACGAGAATGTAGAAGacgaggaggaagaggaggagttcGAGGAAGATGCTGACATGACCATGCCCTTGGGCGCAGATGCGGCTCAAATGGCCAAAATGGCGGTGGAAATGAAGCTAGAGCAGCCCAGTGGAATACCTGTGTCCAACTCTGGAGGACCACGTCCCAAGACCGCTTTTCTGTGTCAGTTCTGCGATTTGGGCTATACGCTACCTTCTGAATGCCAGCAGCATGAGAGAACCGCACACGATCCTCATGCTCCGTACTGTTGCACATTTTGCAATTTACTTTTTATCACGCGTACCGCTTTAATTGCCCATATCAAGTCGCTGCACGATATGGATCGTCCCTATGTGTGTGCCCAGTGCAGGAAGGGATTCGTACGGCGCTCCGACCTCAAGAAGCACGCCATCGTCCATACCGGCGTGCGGCCCTACACCTGCAATGTCTGCACAAAGAGCTTCTCCCGAAATACCAATCTGACGAAGCACATGCGCATTCACAGTGGAGAGAGGCCGTTCGTGTGCCAGCAATGTCCACGCTCCTTCCAGACCGCCCAGGAGATGACGAACCACGCGCGCTTGCATTCCGGCGCCAGACCGTTCCAGTGCAACCGCTGTCCGTTCTCTTCGTCGCGCAAGGACAAGCTGGTTGCCCATCAGAACATGCACACTAAGCGAGACGTGGAGCAGATcttacagcagcagcaacaaaacgCCCTGCATCCACCGACCCCGGAGGAGCTGGCGCAACTGCAGCACGAGCTGACGCAACAGttgaagccgaagccaataaCTTCACAGAAGCCCGGACGAAGCTTCCGTTGCGACGTGTGCGACAGGGTCTTTCAACGGGAGCGCGATCTTCAGCGCCATCGGGCGCTTCATTTGGACACGCTGCTGGCCTGTAAGATATGCAATCTGGTCTTCAATCGTCGCGAACAGTTGCAGCGCCACAACCTGGAGGCTCACGGTCCTACCTATACGTGCGCCATTTGCTGTATCACCTTTTTGCAGCAGATCGAGCTGGAGAACCACCTGAAGGTccatcagctgcagcacaAGGTGGCCCAGAGCACCCAGCAGGCCATGATTGCCGCAGCAATTATGCCCCACAAAATGGTCGAACCGACAGCGGTGGTGGCCAAGTTGCCGCCAGTGCAACAGCCACAGGTGCCGCTACAGATGCGCCCTTCAGCCTCAGAGCTCAACTTCTACAGCAACATGATACCCACCATGAATCTGGGCTTCTATAGCGAAACGCGACCCGAGGAATAA
Protein Sequence: MHITQMEAPQPTPNERPNMASSCRLCHRPASTATTPNIFTEGFCDDDKFCIADVCQSVWGVQYDRHEYLPEQICSDCLEVLDDFYKQRRGMKQREAALQEQLKEIIKKDPKYRPGLNGNPGVFEPGDDCEIEEVDPDKVAETSDDEMGSDEENENVEDEEEEEEFEEDADMTMPLGADAAQMAKMAVEMKLEQPSGIPVSNSGGPRPKTAFLCQFCDLGYTLPSECQQHERTAHDPHAPYCCTFCNLLFITRTALIAHIKSLHDMDRPYVCAQCRKGFVRRSDLKKHAIVHTGVRPYTCNVCTKSFSRNTNLTKHMRIHSGERPFVCQQCPRSFQTAQEMTNHARLHSGARPFQCNRCPFSSSRKDKLVAHQNMHTKRDVEQILQQQQQNALHPPTPEELAQLQHELTQQLKPKPITSQKPGRSFRCDVCDRVFQRERDLQRHRALHLDTLLACKICNLVFNRREQLQRHNLEAHGPTYTCAICCITFLQQIELENHLKVHQLQHKVAQSTQQAMIAAAIMPHKMVEPTAVVAKLPPVQQPQVPLQMRPSASELNFYSNMIPTMNLGFYSETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487472;
90% Identity: iTF_00536228;
80% Identity: -