Basic Information

Insect: Drosophila longiperda
Gene Symbol: Hr39
Assembly: GCA_035042125.1
Location: JAWNLV010000012.1:945424-948539[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 1.8e+04 -6.6 16.5 43 206 43 224 22 230 0.46

2 3 2 1.8e+04 -11.1 28.4 46 140 223 339 202 386 0.31

3 3 5.2e-99 4.6e-95 319.4 15.9 1 408 517 914 517 914 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	1.8e+04	-6.6	16.5	43	206	43	224	22	230	0.46
2	3	2	1.8e+04	-11.1	28.4	46	140	223	339	202	386	0.31
3	3	5.2e-99	4.6e-95	319.4	15.9	1	408	517	914	517	914	0.86

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCTGAAAACATGTCGACGGCGACAGTGATGCCAGCGTcgcagccgctgcagcagcagcagcaacagcagcatcagcagcatcagcagcgtcACAATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAACTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcatAGCGGCAGCCTGCGCATTCCACTCGGTGGCCATGGGGATGAGTCCGACTCGGATGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGGCGACGTGTGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAATGAAACGAATGGCGGCGCCGTCGGTGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAGgtgagcagcagcaccagcagcagcagcagcagtgccacAACGCTGGCCGGCAGTCAAGTGAACGCCATGTTGCAGCCCATTAAAACCGAACTGGAGCACATAGCCGGTgagatgcaacagcagcagcaactgcagcagcaacaacaacaacaacagcagcagcaacaacaacagcaacagcagcaacagcatcagcagcagcagcagcaactgcaacagcaacaactgcagcagcaacaactccagctgcaacagcaacaacaattgctgccaCTGAAGCAACAGAGCTATGCACCGAACAACAAACTGAAATTGGCGCCAACACAAAGTGATCccatcaatttaaaatatgagccaacgacaacgacaacatcaTCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccgctgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGTCCCTCCCAATCCCCATTGACGTCCCGCCACGCCCCCTACACGCCATCGCTGAGCAGAAACAACAGCGATGCGTCGCACAGCAGctgctacagctacagctccGAGTTCAGTCCCACCCACTCACCGATTCAGGCGCGTCATGCGCCACCCGCTGGCGTTGCTGCCTTGTTTACAGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCTGCACAGGAGGCGCAAAACCTGAGCATGGATGCGGGTGGTGCTGCGCTGGATGCCAGTGCCACGTTGGCCGCCTCGCCGGCGGGCATATCGCGTCAGCAGCTGATCAATTCGCCGTGTCCGATTTGTGAGGATAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTCAGCATCTCGACGCGCAAAAAGTGCCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAAGCGATTCGCGAAGATCGCACCCGAGGCGGTCGTTCCACGTATCAATGCTCCTACACGCTACCCAATTCAATGCTCAGTCCGGTACTCAGTCCGGATCAGGCggcagccgccgccgctgttgtcaatcagcagcagcagcagcagcatcagcaccagcagcaacatcagcaacaccaacaacagcgacttcaacagcatcagcatcaacaacaacaacagcaacaacagcaccagcagcagcaacatggtCCACTCAATGGCTTTGGTGGTGGTGGGTCCAACTCGCTGCCAGCGAGTCCCAGTCTTGGCGGGGCATCCATCAAGACGGAGCTAGCGGAGCAGCTTAATCATCATACGTTATTATCAACGCGAGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACAGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCATCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAAATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAATGGCGAAAACGCCAATCCCGATCTGATTGCACACCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATTTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGACACGCCCGGCGAGATCAAGATGTCACAGGGCCGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGTATTGAGCGCATGTTGAATCTGACGGATCATTTGCGACGCCTGCGCGTGGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCTGACACAACGGAACTGCACGAGGCAGTTAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAAACGCGTGATGGtgctgattttaatttgctaatgGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATVMPASQPLQQQQQQQHQQHQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGHGDESDSDAELANIENLKVRRRVADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSSSSSSATTLAGSQVNAMLQPIKTELEHIAGEMQQQQQLQQQQQQQQQQQQQQQQQQQHQQQQQQLQQQQLQQQQLQLQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFTGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICEDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPVLSPDQAAAAAAVVNQQQQQQHQHQQQHQQHQQQRLQQHQHQQQQQQQQHQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTELAEQLNHHTLLSTRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: -