Basic Information

Gene Symbol
Aef1
Assembly
GCA_018903485.1
Location
JAEIGF010000408.1:7543048-7544110[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0065 33 4.5 0.1 21 48 206 233 199 237 0.86
2 4 1.9e-05 0.096 12.6 0.1 21 52 234 265 232 266 0.89
3 4 0.03 1.5e+02 2.4 0.1 21 48 262 289 260 293 0.85
4 4 8e-05 0.41 10.6 0.1 21 47 290 316 285 323 0.88

Sequence Information

Coding Sequence
ATGATGCATATCAAGAGCCTGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTCCCGCGCCACCCTCGGCACACACGCTGGCTCACCTGGTGGCCAATGCTACGCATAGTCCGACGCTTGGCGAATCGCACTATGTCAGCAACGGTCACTCCAACAACGAGCATTCGGGCGAGGGTAATGGCTCGAGCGGCAGCGGCGGCCGGGAGCCGGAGAAACCGTTCCATTGCACAGTGTGCGATCGACGATTTCGCCAGCTGAGCACATTGACCAACCATGTGAAGATCCATACCGGCGAGAAGCCCTACAAATGCAACGTTTGCAATAAGACGTTCCGTCAATCGTCAACACTGACGAATCATTTGAAAATTCATACCGGCGAAAAACCATACAATTGCAACTACTGTCCCAAGCATTTCCGTCAGCTGAGCACTTTGGCCAATCATGTCAAGATTCACACGGGTGAAAAGCCGTTCGAGTGCGTCATATGCAAGAAACAATTCCGCCAATCCAGCACGCTCAACAATCACATAAAGATCCATGTTATGGACAAGGTCTACGTTCCTGTCAAGATCAAAACGGAGGAGGACGAGGGGTGA
Protein Sequence
MMHIKSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPAPPSAHTLAHLVANATHSPTLGESHYVSNGHSNNEHSGEGNGSSGSGGREPEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCNKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00475494; iTF_00534801;
90% Identity
iTF_00534801;
80% Identity
iTF_00534801;