Basic Information

Gene Symbol
-
Assembly
GCA_018903485.1
Location
JAEIGF010000593.1:8252048-8257917[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.042 2.6 8.5 0.3 1 23 1291 1314 1291 1314 0.94
2 13 7.3 4.6e+02 1.4 0.2 1 23 1479 1501 1479 1501 0.91
3 13 0.00016 0.01 16.1 2.7 2 23 1504 1525 1504 1525 0.97
4 13 6.3e-05 0.0039 17.4 0.2 3 23 1533 1553 1531 1553 0.98
5 13 5.2e-07 3.3e-05 23.9 4.1 2 23 1560 1581 1559 1581 0.97
6 13 5 3.1e+02 1.9 0.4 5 23 1594 1612 1592 1612 0.96
7 13 1.2 77 3.9 5.4 3 23 1619 1640 1617 1640 0.93
8 13 0.13 8.2 6.9 0.2 2 23 1651 1671 1650 1671 0.96
9 13 5e-05 0.0031 17.7 0.4 1 19 1677 1695 1677 1699 0.95
10 13 1.4e-05 0.0009 19.4 0.5 1 23 1707 1729 1707 1729 0.98
11 13 9.4e-05 0.0059 16.8 7.6 1 23 1735 1757 1735 1758 0.96
12 13 0.00018 0.011 15.9 5.9 1 23 1763 1785 1763 1785 0.98
13 13 0.026 1.6 9.1 8.2 1 23 1791 1813 1791 1814 0.95

Sequence Information

Coding Sequence
ATGGTGGACTGTGTGCAGTGCCCCGTGTGCACGCTGTATTTGCATGCGGGCATGAATCTCTCCGATCATTTGGAGACTCATCCCAAGGAGCAGGTCATCAAGGCTCTGGTGCAAATGACCATAGCCGGCAACAATGGCATGGGCAGCGCCCTGGCTGCAGCTGTGCTCTCCTCCGGCAGCGCGGCGGCAATAGATGGCGGCGCTGCATCTAGCTCATCCTCATCCTCATCATCATCATCATCCTCGACGACGGCGGCTGATGTGAAACCAGTTGTGCTAGACGCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATTGAGCAATCCACCGATTAAGGCAGTTAAAAGCGCGCCACCCACGACTGAGGCGCCAGCCAACACATCCAATACACCCACCACTAGCAGCATGAGCGCCATTTATTCCGACTATCGCTATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGGCCATGAAGTACACCTATGCAGCAGCGCTTCCACCGCCGCCGCCGCCGCTGCAGCTCTTTGCACAGCAGGCGACGTCAACGCAGTCGCATCAGAAGCCACCACCCGCCTATGGCGCCGCCATCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACCGTTAACCTTGCACCACCGAGTGGCAAACATGGCAAAGTCCATACGGATATCTTCTTGAATCCACCGCCTCCACCAGCGCCACAGCTCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGACTGCAACATGCGCAACAGCACCAACAATCTCTTGCAGCCGGCAGCTATGCAGGTGCCAACTGCCCCAGCTCCTCTGCGACTTTGATGTCATCCACCTCCGTCGGACGCGCCAGCAGCTGTCGCCAAACGAGCAATTCGCCTTTTGGTGCGCTCTTAAATGCCGCAGCGCAGGCCGCCTGCGCCTCGCCCGTTACCTCCAGTGCGTCTGTGCTGCGCTATGCCGAGTCACCAGTGGCCCACTATCTAGAGCGAGAGAATGGCGATTTCATAGTCCAGGAGACGCCCAAGCACATTGTGGAGTGCGTCGAGAAGGATGACGGCGAGTTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTGCTGCACATACACGACGATGACGACGACGAAGAGGAGGATGAAGATGACAAGGGCTGGAACAGCGATGATGAGGATCACATGAAGGTGGAAGATCATGTAGAGGATGGCGACGACGAGCACGAGGATAGCCGCAGCAGAGTTGCACCCAAAACCACAACGAAAAAGTCACGCAAGACAAAAGCCAATGGCAGAAAGCACAAACGCGCCAGCAAGCATCAGCCAGAAGATGAGGACGACTTTATGAGTCTAGGCAGCAGCTGTGCCGAAAGTGAACATCATGCAGAGCAGCAGCAGCAGCAGCAGACGCAGGTGCAGCTGTCGCTTGCGTCCTCTTCGCCAGTTCAGCTGAGCACGGCGCCGTCGACGAGCAGTGGAGCAGCTGGTGGTGGTGCTGTTGCCACCGCGTCCCCCTCTCCCACCTCTTCTGGCAGTGCCAACTCGACGCCCAGCGGCTCCACAAAGTCCAAAAAGAATCGCGTGACGGTACTCAGCGATGTGCCGCTCAACATGAACGAGTATTTGGATCTGGTGGGCAACATTGTGGCTTCAGGGCGCATTGGTGCAGCTCGTCCGTTTGCCGCCGTGGCTCCCATACCGTTGGTCAAGGTGGAAAAGGAGGAGCCAATGGACGACTACGACACCGTACAGCCTGAAATGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAAGTGGAGCCAACGATGCTGCTGCCGCAACGCTTTTCAGCTCCGGCGCAGCAGCGTGGACCCAAGAAATTAGTCATCAAGCCAAAGGCCACAGCGACGGCAACGACAAAAAAGACTGAGAACAACGCTGCCGAAACAGCCAGCATATCAAAGGCGTCCACAGAGCTGGTGCAGGTGAAGAGCGAGAATGTGGAGGCAGCCGTAACAACGAGCGGCAGCATACTAGAGAAGCATCTGACTACCAGCTATGCGGCACAGCAGCAGGCGCGCAAACACTCTGCAGTCAACGATGATGATGCTCGCGTGCTGCTGGAGTTTGCCAACTCGAAGCAACTGCCGCTAGCGGGGAACAGCAACCAGACCACGTTTGTGGTTAATGCGGCCAGCTTTGCCTCGGCGGGCTCCGTATTTGCCAGCGGCAGCAGCGGCAGCGCGAAGAAGTCAAGCAAGCCGGGCGACGAGTACATTCTGCCTGATGATAACAATCTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCATCCTATGCCTCTAATTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCCACGCTGGCCTCCTCCTCTAGCAACTCATCGGTTATGGATCAGGATTGCTCCATGAATGCCACGTTTCGCTTGGGCAAGCCACAATCCACATTGGCTGGCTGGTATCAGCCGCAGCAGCAGCAGCAGCAGCCACAGGCAAGCAGTTCGCACAGCTCCCATGTGGAACAGTCGAGCCATTTTATAGCCGCACTCGCAGCCGTTGACTGCTGCAACAGTGTGGCGGGCGTTGATAGCGATGTCAAGTATTTGGATCTGGATACCTGCAAGCGGGAGCAGTTAAGCAACAGCAGCAGCCATTTGCCTTCTGTATCCGCATCCGCATCGACAACATCCTCATCATTTGCGGCCGCCGCCACGGAGAGCAGTCTGGTTAGTGGCTTGGGCCTAAACATACGCACCGATGAGAAAATGCCCGCCAAGGGTGAAATCTCCGAGCAGGAAAGCAACTGCGATATTGAGAACTCCTGGAGTCAATCGATGTATGGTGACATATCACAGCGCTATTTTAGCAGCTATCATCAGCTGGCCGATTGGCGTCACGATTCCTATCCGCCGCAGGACCTCAGTGGCCAACAGCAGCAGCGTGAGCCAAAGCGCTTTGATTTTAACGCTGTTGCCTCGGAGTACGCGCAGTCGGGCGAGCTGGACGCCTCCCCGAGCTCAAATAGACACAATCATTTGTTGGATGCACAGCCCACTGCTTCCTCGTCGTCATCGGCTTTGATGGCTGGTCCACCAATAGCCTCGACGTCACGTGCTGCTGCCGAAGCGGAGGCCGTTGCTGCAGCGCTGGCGCAACGAAAGCCACCGCGTCGCAAGATCTATAAGTGTCCGCACTGTGTGGTCATCTTTGAGAAGCTGAAGGAGCGCAATGCGCACATGATTGGCGAACACAACTATGTGCGCCAGAACCGACGACTCATCTGCACGCAGCCACAGGTTAATGCCACAATGCTGGCACAGCCGCCGGCTCAGGAGCAGCAACAGCAGCTCCAGCAGCAAGTCCTGCTGCAGTCTGTGGGGCAAAGCAATGGCGATGTTGTGCATGAGGATTCCAAGGATGGTATTGTAAAAATCAAGCAGGAACACTGCCAAGATAAACAGGATTCAACGGAGCAGCTACTTGGCCAAATGGATATGCCCGATGTCAAGGATGCTGGCCTGCTAGATGCCAGCGCTGATAATGGTCGCGATGCGGACATGAAGCCACCAGCCAACGTCTCAGAGCTGGACGAGAAGCCACCCATAGCGCCGTTAGCCATGACCACACCAGCTGCCAAGCTGGCTGCTCTATATCGCATGCTCATTGCGTACAATGAGTCCAAGCTGGGCCAGGAGCGCAACAATCTTAGCGAGCTGGAGCAAAAGGCCATGGAGAAATCCATATTCCTCTGTTATGTGTGCCGCACCGATTTCCCCTCCGTAAAGCTGTACGATGCACATTTGACCGAGCATCCCGCTGAGTGTTTCACCTGTGGCAAGAAATTCTATCGTTGGAAGAACTTTTCACTGCATTTGAAAAGGCATCTGGGCTGGAAGGAGTTCGGCTGTTATGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCGCTAGTGGAGCACATGCGCATGCACACGGGCCAGACGCCGCTCAAGTGCAAGATATGCGGCAAAAAGTTCAAACGTTATTCGAACTTGACACAGCATCGTAAGCGTCACACCAAAATGATGGTGCGCAAAAAGGAGTACGTGTGCCATTGTGGCGAGGTGTTGCCCTCCAAGGCGCGCTTCCTGTGGCACAAGGAGACCCACGACTTGAAGCCCAAATGCTGTCCGTATTGCTGCGATCGTTTCGTGCATGCCAATTCGCTGCGAAGGCACATTCGACTGGCCCATTCGGATAAGTTTGATTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACCTCCATCAAAGCGCACATGGCGACACATTCGACAGATCCGCAATACGATTGCGCCATATGCAACAAGAGCTTCTCTACCAAATGGAATCTGAAGATACATTCGTGGGTGCATGCGAATCGCACGGCCAAACCGTTCAAGTGCGAATACTGCCCCAAGGCGTTCGTTCGCGAGCTGGACTTCAAGAACCACATGAATGCCCATAAGCAGATCAAGCCCTACACCTGTGAGTATTGCGGCTGCAAGTTCATACGTAAATACAATTATATGCGGCATCGACGGGAGCATCATGGCAACAAGAAGTTCACCTGCGACCAGTGCGACAAGTCTTTTCATCGTCATTATTATCTGATCGAGCATCGGCGCATCCACACCGGCGAGCGTCCCTTCCACTGCACCATCTGCGGCAAGAGCTCGACGACAAAGACCAATCACAATAAGCATCTGAAGATACATCATTCGCGGGATCCTTTTACCGTCGAGGTTTAA
Protein Sequence
MVDCVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNGMGSALAAAVLSSGSAAAIDGGAASSSSSSSSSSSSSTTAADVKPVVLDAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLSNPPIKAVKSAPPTTEAPANTSNTPTTSSMSAIYSDYRYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSAMKYTYAAALPPPPPPLQLFAQQATSTQSHQKPPPAYGAAIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTVNLAPPSGKHGKVHTDIFLNPPPPPAPQLXXXXXXXXXXXXXXXXLQHAQQHQQSLAAGSYAGANCPSSSATLMSSTSVGRASSCRQTSNSPFGALLNAAAQAACASPVTSSASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDDDEEEDEDDKGWNSDDEDHMKVEDHVEDGDDEHEDSRSRVAPKTTTKKSRKTKANGRKHKRASKHQPEDEDDFMSLGSSCAESEHHAEQQQQQQTQVQLSLASSSPVQLSTAPSTSSGAAGGGAVATASPSPTSSGSANSTPSGSTKSKKNRVTVLSDVPLNMNEYLDLVGNIVASGRIGAARPFAAVAPIPLVKVEKEEPMDDYDTVQPEMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVEPTMLLPQRFSAPAQQRGPKKLVIKPKATATATTKKTENNAAETASISKASTELVQVKSENVEAAVTTSGSILEKHLTTSYAAQQQARKHSAVNDDDARVLLEFANSKQLPLAGNSNQTTFVVNAASFASAGSVFASGSSGSAKKSSKPGDEYILPDDNNLEVDEIVISSSSSYASNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXATLASSSSNSSVMDQDCSMNATFRLGKPQSTLAGWYQPQQQQQQPQASSSHSSHVEQSSHFIAALAAVDCCNSVAGVDSDVKYLDLDTCKREQLSNSSSHLPSVSASASTTSSSFAAAATESSLVSGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFSSYHQLADWRHDSYPPQDLSGQQQQREPKRFDFNAVASEYAQSGELDASPSSNRHNHLLDAQPTASSSSSALMAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVVIFEKLKERNAHMIGEHNYVRQNRRLICTQPQVNATMLAQPPAQEQQQQLQQQVLLQSVGQSNGDVVHEDSKDGIVKIKQEHCQDKQDSTEQLLGQMDMPDVKDAGLLDASADNGRDADMKPPANVSELDEKPPIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00563356;
90% Identity
-
80% Identity
-