Basic Information

Insect: Drosophila littoralis
Gene Symbol: -
Assembly: GCA_018903485.1
Location: JAEIGF010000592.1:1174898-1179504[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.6 6e+02 1.0 1.9 3 16 57 70 56 72 0.84

2 14 4.1 2.6e+02 2.2 1.1 1 23 172 198 172 198 0.76

3 14 0.00023 0.014 15.6 0.7 1 23 204 227 204 227 0.97

4 14 6.3e-05 0.0039 17.4 4.6 1 23 232 255 232 255 0.96

5 14 0.0004 0.025 14.8 4.5 1 23 260 282 260 282 0.98

6 14 5 3.1e+02 1.9 5.7 2 23 289 312 288 312 0.90

7 14 0.00044 0.027 14.7 1.0 3 23 322 343 321 343 0.95

8 14 0.024 1.5 9.2 0.3 1 23 349 372 349 372 0.95

9 14 0.12 7.8 7.0 0.2 5 23 388 407 383 407 0.89

10 14 4.1e-05 0.0026 17.9 0.4 1 23 436 458 436 458 0.98

11 14 2.5e-06 0.00016 21.7 4.2 1 23 464 486 464 486 0.97

12 14 8.1e-06 0.00051 20.2 0.1 2 23 493 514 493 514 0.97

13 14 0.0011 0.069 13.4 0.9 1 23 521 543 521 543 0.99

14 14 0.00071 0.044 14.0 5.0 1 23 549 572 549 572 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.6	6e+02	1.0	1.9	3	16	57	70	56	72	0.84
2	14	4.1	2.6e+02	2.2	1.1	1	23	172	198	172	198	0.76
3	14	0.00023	0.014	15.6	0.7	1	23	204	227	204	227	0.97
4	14	6.3e-05	0.0039	17.4	4.6	1	23	232	255	232	255	0.96
5	14	0.0004	0.025	14.8	4.5	1	23	260	282	260	282	0.98
6	14	5	3.1e+02	1.9	5.7	2	23	289	312	288	312	0.90
7	14	0.00044	0.027	14.7	1.0	3	23	322	343	321	343	0.95
8	14	0.024	1.5	9.2	0.3	1	23	349	372	349	372	0.95
9	14	0.12	7.8	7.0	0.2	5	23	388	407	383	407	0.89
10	14	4.1e-05	0.0026	17.9	0.4	1	23	436	458	436	458	0.98
11	14	2.5e-06	0.00016	21.7	4.2	1	23	464	486	464	486	0.97
12	14	8.1e-06	0.00051	20.2	0.1	2	23	493	514	493	514	0.97
13	14	0.0011	0.069	13.4	0.9	1	23	521	543	521	543	0.99
14	14	0.00071	0.044	14.0	5.0	1	23	549	572	549	572	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCAAGGTGCGATTTCGAAAATGGCAACAACTATTGGCTGGACATGTTCCATCCAACGCGTTGGCAGAGCGAGATGGCGCAAATCCGCCTGGAGTTTGTCAACTGGAAGTTACAGATCTCACCAAACGATGGACTGCCGCAAAAAATTTGCAGCGATTGCTTTACAAAATTCTGCTCCATATACACATTTCGCATGGCCTGCCAGGACGCACAGTTAAAGTTGTCGAATATTTTTGATAAAATCGATGCAAATTCGCTCTACGATAAAAACGACGAGGACAATATTGAGGAGGATGTGGTTGAAATAGAAGCGGCGACCGAAATAGAAACAGAAACAACGACAACAACACAAAAAAACACTGCCAATATTGAGGACAACACCGAAACACCCATAGAAATCTTTGTGGAAACGATTAGCATCAACGAATCTGAATCTTTACAACCAGATGAGGAGACCGATTTAGCTTCAGATTACAGCACATTAAACATAAGCTATGCTTGTAAATTTTGTCACAAGCCACAGGAAAGCTATGAGCTGCAGCACCTATTACTAGAGCACATCAGCAACGCACACGATCCGGATCAGCCCTACAACTGTCCGGAGTGCACGGAGTGCTTCCAAGATGCCGCATCGCGTACCGTGCACATGAAGAGCGTGCATGTGGTAAAGCATCACACCTGTGAGGTGTGCGGCAAAAAGTACGGCGATCGTCATAATCTCGAGCATCATATTGAAAAATATCACTCGGAAACGGATTTCGAGTGCAGCCTGTGCGAGAAACGTTTCTTTACGCGCAAAAGCCTGCACTACCACATGAACTGGCACAATCCGGAGCGCCAGCTCAGATGTCGCCACAGCGGCTGCGACAGGCTGTTCATCAACCAACGACATCTCAAATGTCACGAGGCGACGCACTCAACGGGCCCCCGCAAGAGCGAATACTGCGGCTTCTGTGGTAAAGCTTTCATACACGTTAAAACCCTACGTTGGCACATCTATCGACAGCATGGCGGGGAGAAGCCTTTCAAATGCGCCAACTGCACGGAGGTTTTTGGCTCCTATGCGGAAAAGCGCTTGCACATGCTGGAGCGGCACACGGAAAATCTGACGCATCAGGAGCGCAGCGAATGCATGTTTCAGTCCTGTCGCCAGGAGTTCGACACCGAACAGGAGCTCATCCAGCACATGAGCGTTGAGCATGTGCAGCGCGAACCCTCCACGCCGATAATTGCGAATAATAAACGCGTGCTCCAGTGCAAACGGGAGCGACAGTATACGGGCCTCTTCCAGTGCGCCAGCTGCACGCAACGTTTCAACATGAAGTCCGCCCTGGAGCGGCACATGGCTGTCCATTCCGCTGACCGGCTGCATGCCTGCCCGCACTGCTCCAAGCGCTACAAGCGCGCCCAGGACCTGAAGTGGCACATGAAGACGCACGCCAATGAGAAGCCCAATGTGTGCGATGTCTGCGGCAAGGCGTTTGCCCTCAAATATGTGCTCACCCAGCATATGCGCAGTCATGAGGTACTTGAAAAGAACTTCAAGTGCGAGACCTGCGGACGGGCCTATCTGTTTGAGAAGTCTCTGCGTCTGCATCAACGCGTTCACACGGGCAACACCTACTACAAGTGCGATCTGTGCCAGGAACGTTTTGTCACTCACATCAAGTTTAAAACCCATATGAAAAAGACACACGATAGCAGCCAGTCACATGCCAAAGATACGCTGGATGATTTGATCAACATTGTGATTTCCTGA
Protein Sequence: METCRTCARCDFENGNNYWLDMFHPTRWQSEMAQIRLEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDANSLYDKNDEDNIEEDVVEIEAATEIETETTTTTQKNTANIEDNTETPIEIFVETISINESESLQPDEETDLASDYSTLNISYACKFCHKPQESYELQHLLLEHISNAHDPDQPYNCPECTECFQDAASRTVHMKSVHVVKHHTCEVCGKKYGDRHNLEHHIEKYHSETDFECSLCEKRFFTRKSLHYHMNWHNPERQLRCRHSGCDRLFINQRHLKCHEATHSTGPRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCANCTEVFGSYAEKRLHMLERHTENLTHQERSECMFQSCRQEFDTEQELIQHMSVEHVQREPSTPIIANNKRVLQCKRERQYTGLFQCASCTQRFNMKSALERHMAVHSADRLHACPHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKTHDSSQSHAKDTLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00531129;
80% Identity: -