Basic Information

Insect: Drosophila limbata
Gene Symbol: zfh1
Assembly: GCA_963924055.1
Location: OZ001352.1:25125148-25153819[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0061 0.62 11.3 1.8 2 23 76 98 75 98 0.95

2 9 0.00062 0.062 14.4 0.1 1 23 280 302 280 302 0.97

3 9 9.1e-05 0.0091 17.0 2.0 3 23 317 337 315 337 0.97

4 9 8.6e-05 0.0086 17.1 4.9 1 23 346 368 346 368 0.98

5 9 0.00024 0.024 15.7 1.4 3 21 376 394 374 395 0.94

6 9 0.0079 0.8 10.9 0.7 2 21 653 672 652 673 0.92

7 9 1.5e-05 0.0015 19.4 0.5 1 23 1015 1037 1015 1037 0.94

8 9 5.7e-05 0.0057 17.6 7.4 1 23 1043 1065 1043 1065 0.98

9 9 0.0028 0.29 12.3 4.3 1 21 1071 1091 1071 1092 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0061	0.62	11.3	1.8	2	23	76	98	75	98	0.95
2	9	0.00062	0.062	14.4	0.1	1	23	280	302	280	302	0.97
3	9	9.1e-05	0.0091	17.0	2.0	3	23	317	337	315	337	0.97
4	9	8.6e-05	0.0086	17.1	4.9	1	23	346	368	346	368	0.98
5	9	0.00024	0.024	15.7	1.4	3	21	376	394	374	395	0.94
6	9	0.0079	0.8	10.9	0.7	2	21	653	672	652	673	0.92
7	9	1.5e-05	0.0015	19.4	0.5	1	23	1015	1037	1015	1037	0.94
8	9	5.7e-05	0.0057	17.6	7.4	1	23	1043	1065	1043	1065	0.98
9	9	0.0028	0.29	12.3	4.3	1	21	1071	1091	1071	1092	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCGACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTACTCCATGCAGTTTCCCTCCTTGGCCTCCAGTTTGCATCACCATCCAGCGCACAGCAAGCCCAGCAATGTGGCTGCAAATGAGCAGCTTGCCACACATGCGGCAAGTGCCGCAGCGAATGCGGCCGATGACTATTCGGTCAAATGCACGCAGTGCCACAAGCGCTTCAACGAGTTTCAGTCCCTCAGCGAGCACATTGCCAGTGAACATCCGCATGACAAGCTCAATTATGAGCCACATCGCGCTGTTGTCGCTGTGCAGCCGGAAAGCGACGCCGAGGAAGATGAACAGAGCAATTTGAGCAGCAACAGTCGACGCTATGCCAAGTCCCCAtccagcaacaataacaacaacaatgagacgGCCAAgaatcaaaataataacaacaataataatcacAGCAGTCAACACTCGCCCATGTGCTCACCCGTTCCCCAAGCACCGCCCGCTGATCTTTTCGCCCACCTGCCTCATCCGCCGCCGCAGCTGCCCGCCCACTTGCATGCCCAGTTCATGGCCGCCGCCGCCTCACTGGCCATGCAATCCGCTCGCTCCGCCAGCTCGCCCAGccaacaacagttgcaacagtcgccgcagcagctgcagcaccAGCAGtcgcaacagttgctgctgccaccgcCACAGcccggcagcaacagcagcgtcGGCAGCAACTCCGCCTATGATCTGGACCTGAGTGCACCACGATCCACCTCCAGTCCGGGCTCCACAACTGGCGAGCTCAGCGTCCCCTTTCCCTGCATGCAATGCACCGCGGCATTTGCCACTCGCGATCAACTCGAGCAGCATCAGTTGCTGCACTCGCCCACGGGACAGCAGTCGTCGCAGTCGGTGCCACAGATTTGCAAAAAATGCCACAAGGCATTTGCCAATGTATATCGCCTGCAGCGTCACATGATCAGTCACGATGAGTCGACGGCGTTGCGTAAATTCAAGTGCGCACTGTGCGAGAAGGCGTTCAAGTTTAAGCACCATCTCAAGGAGCACGTGCGCATCCATTCGGGCGAGAAGCCCTTTGGGTGCGACAAGTGCGGCAAGAGATTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACCTCCAAGAAGTGCATCAGCATGGGCCTCAAACagaccagcaacaacaacaacaacaatggtaacagtggcaacaacaacaatcgacaGATGCTCAAAGCATTGGATAAAAATGTCGGCGCTGGACGCTCGCCAacggaacaacagcagcaacaacaacaaaagcgcgTCTCCAAGTTGCCAATGCCAGAATCGAATCCCTTGCTGCCCAATCCCATGAACTACTTTGCCGGGGAGGCACAGGGGCCGTCGGCAGCAGCGAATCCCGTAGCTCCCTTTTATCCCAGCTACATGAATGCGGCTCTGTTGGCATTTCCCAATGCGTTTATGGCAGCGGCGTTTGATCCACGAATTCCCACGGCATACAGCATACAGAGATTGCTGGAGCTGACAGCCGccggacagcagcagcagcaacaggagcagcagcaacagatggagcatcagcaacatatggagcagcaacaacaacatctagagcaacaacaacaactagagcaacagcaacaactgggGTCCAACAAAGATGAGGATGAGACGCCCGATGAGCCAAAGCTGGTCATGGATCTGGAGGAGTCGGAGACCAAACCAACCACGCCAGAGTTGCCGCCAGTTGTTGTAGCTAATCCCGATGCCGTCGCGCCCAAACAGGAGCAGAGTCGGGAGCCAACGCCGGCGCCGGAAGCTGCAGCAGATTCACCTAAGCCCATTAAGATGGAGCTGGAACAGGAgccggaggaggaggaggtggaggAGCAGGTGACGGTACAGGATTTGCGCTGCAGTCGTTGCTCCAAGCAGTTTAATCATCCCACGGAGCTGGTGCAGCATGAGAAGGTGCTCTGTGGACTCATCAAAGAGGAGCTAGAGCAGCActaccaacaacagcagcaacaacaacaacaacagcagcaacaacagcagcagcaacaacaacatcaatcatCTTTCGTTAGCGATGCAGATGAagatgaggaggaggaggaaccACGACAGGATTATAACGCTGgcggcagcagcgacagcggcgaACGCAAAGTCCGCGTCCGCACGGCAATCAacgaggagcagcagcagcagctgaagcaACATTATGCTCACAATGCGCGTCCATCCCGGGATGAGTTCCGTCTGATTGCCACACGTCTCCAGCTGGATGCACGTGTCGTCCAGGTCTGGTTCCAGAACAATCGCTCGCGTGAGCGCAAAATGCAGAGCTATGTGAGCAGCAATGAGACACCTAGTGTCCAGGCAACGCCACCACAACTGGCCCGAGGAGCTGGCGAGGATCAGCCCCTGGATTTGTCCGTGAAACGGGATGCATCGCCGCTTTATGGCCTGGCGCCACAGCAGCAGACCGCGTTGAGCCAGCCGCCCGTGGACTTTCCCGACAACATGGCCATCAATCTGAGCCGCAAATTGTCGAGCTCGGCATCGATGTCGCCGGCTTCGTTGTCGCCCTGCTCCGCGGCAGCGCTCTACTTTGCCCCGCCCTCGCCGCCCAACCTCCTGCACGAGGCAGTGCCTCCAATGACGCAACAGAACGTCCCAGTGTCACGTGGTCAACCCTTTCCCGGTCTGCCGCCCTACATGATGCCACGGCTACCTATGGAGGCGCTCTTCCAGATGCGCCCGGGCGGCGACTATGCGCCCAATCCACTAATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTGAGTCCCGGTGGATCCGAGAAGCGGTCCTGGCGCGACGACGACTCGCGCATCTCCCACGAGGACGACTATGTGATGGCCGGCGCGGGAGGACTGTTGCCCCCGAAGCCGAAGCGCGCCAAGGCCGAGACGCATGGACACGCGGGCGATCCCGACCTGCCCTTCGTCTGCGACCAGTGCGACAAGGCGTTCGCCAAGCAGAGCTCCCTGGCACGCCACAAATACGAGCATTCCGGTCAGCGACCTTATCAATGCATGGACTGTCCCAAGGCCTTCAAGCACAAGCATCATTTGACGGAGCACAAGCGCTTGCATTCCGGCGAGAAGCCATTTCAGTGCTCCAAGTGCTTGAAGCGCTTCTCGCACTCGGGCAGCTACAGTCAGCACATGAACCATCGGTACTCCTATTGCAAGCCGTATAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIQQSMPSSTAYSMQFPSLASSLHHHPAHSKPSNVAANEQLATHAASAAANAADDYSVKCTQCHKRFNEFQSLSEHIASEHPHDKLNYEPHRAVVAVQPESDAEEDEQSNLSSNSRRYAKSPSSNNNNNNETAKNQNNNNNNNHSSQHSPMCSPVPQAPPADLFAHLPHPPPQLPAHLHAQFMAAAASLAMQSARSASSPSQQQLQQSPQQLQHQQSQQLLLPPPQPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGELSVPFPCMQCTAAFATRDQLEQHQLLHSPTGQQSSQSVPQICKKCHKAFANVYRLQRHMISHDESTALRKFKCALCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCISMGLKQTSNNNNNNGNSGNNNNRQMLKALDKNVGAGRSPTEQQQQQQQKRVSKLPMPESNPLLPNPMNYFAGEAQGPSAAANPVAPFYPSYMNAALLAFPNAFMAAAFDPRIPTAYSIQRLLELTAAGQQQQQQEQQQQMEHQQHMEQQQQHLEQQQQLEQQQQLGSNKDEDETPDEPKLVMDLEESETKPTTPELPPVVVANPDAVAPKQEQSREPTPAPEAAADSPKPIKMELEQEPEEEEVEEQVTVQDLRCSRCSKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQQQQQQQQQQQQHQSSFVSDADEDEEEEEPRQDYNAGGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIATRLQLDARVVQVWFQNNRSRERKMQSYVSSNETPSVQATPPQLARGAGEDQPLDLSVKRDASPLYGLAPQQQTALSQPPVDFPDNMAINLSRKLSSSASMSPASLSPCSAAALYFAPPSPPNLLHEAVPPMTQQNVPVSRGQPFPGLPPYMMPRLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVMAGAGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537703;
90% Identity: iTF_00585867;
80% Identity: iTF_00533700;