Dleo016090.1
Basic Information
- Insect
- Drosophila leontia
- Gene Symbol
- -
- Assembly
- GCA_008042735.1
- Location
- VNKB01017366.1:25203-31716[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0038 0.32 11.6 0.8 1 23 1304 1327 1304 1327 0.97 2 13 6.6 5.6e+02 1.4 0.2 1 23 1484 1506 1484 1506 0.91 3 13 0.00015 0.013 16.0 2.7 2 23 1509 1530 1509 1530 0.97 4 13 5.6e-05 0.0048 17.3 0.2 3 23 1538 1558 1536 1558 0.98 5 13 4.7e-07 4e-05 23.9 4.1 2 23 1565 1586 1564 1586 0.97 6 13 4.4 3.8e+02 1.9 0.4 5 23 1599 1617 1597 1617 0.96 7 13 1.1 95 3.8 5.4 3 23 1624 1645 1622 1645 0.93 8 13 0.12 10 6.9 0.2 2 23 1656 1676 1655 1676 0.96 9 13 4.5e-05 0.0039 17.7 0.4 1 19 1682 1700 1682 1704 0.95 10 13 2.8e-05 0.0024 18.3 0.4 1 23 1712 1734 1712 1734 0.98 11 13 8.4e-05 0.0072 16.8 7.6 1 23 1740 1762 1740 1763 0.96 12 13 0.00018 0.015 15.8 6.5 1 23 1768 1790 1768 1790 0.98 13 13 0.0022 0.19 12.4 6.1 1 23 1796 1818 1796 1819 0.96
Sequence Information
- Coding Sequence
- ATGGTGGACAACAGCGTTCAGTGCCCCGTGTGCACCCTGTACCTGCATGCGGGTATGAATCTCTCCGATCACTTGGAGACTCATCCCAAGGAACAGGTGATCAAGGCGCTGGTCCAGATGACGATTgtcggtggcggtggcaacaACAGCATGGGCAGCGCCCTGGCGGCCGCTATGATGtcaggaggaggcggaggaggcggtgggTCTGATGGCGGAGAAGCCAGCCTGGCAGATGATAAGTCTGCCTTTACATTGTCACCACAATGTGGCGATGTGAAACCAGTTGTGGCCACCAGCCCGCCAGCGATGTCCAAAACCATATCAGCTGCAATGCCCGTAGTGccgccagcaccaccaccgtTGCCGCCGCTCTCCTCCGCCAATGCTGCACCCTCCTGCACATCCCCTTCTGCAAGTAGCAgcactagcagcagcagcaatctgAGCAATCCACCGATGAAAGCACTGAAATGCGCACCGCCCACGACTGAGGCGCGAGCCAACACATCCGCACATCCCACCATAAGCAGCGTATCCACACAGTATCAGCCGTCGCTGGTTGCTCCGGATTATCGCTTcaatcaccagcagcagcagcagcagtcgggCTTTGGGCGTGGTGTTGCTGGCACCAACGCAGCCACGCTGGTAATACCGCAGGTTGCGCAGCAGCACTTCCTTGCCAGccatcagcagcaggcccACTTTacgcatcagcagcagcaacaacagcagcagcagtcgcccCTAAAGTTTACCTATGCCACCGctttgccgccgccaccgccgttGCAGCTGTTtacgcaacagcagcagcagcagccgacgGCAGCTTCAACGCAGCCTCACCAGAAACCACCTCCCGCCTACGGAGCCGCCATCAGTCAAATACGATCTCAGCACAACCAaatcaagcagcagcagccacatcaacagcagctgcagcagcagcagtcacagCCACCCCACATGGCCGGGCAGCACAACCTAACCCTGGCACCACCGACACCAACAGCAGAAGTAGCTGGAAAGCAGCCCAGCAAGGCGCATGCGGAAGTATTTCTGAAtcccccaccaccaccaccgccgccgtcaCAGGCACAGGCCACGGTATCGATCCACAGCATGGGACAGAATCATCAGAGTCATCCTCATTTGCAACAGCAGattcaccagcagcagcagttgacCACATCACCATCCTCAAGattacagcagcagcagcagtcactAAGCTTGCAGACCTACGGACCGGTCTCAGTGAGCAGCAGCTGTAGCTCCAGCTCTGCTTCCAACTCTGgatccgctgctgctgcgtctggTAGTAGGAGCAGTCGGCAAACCAATTCACCATTTGGGGCTCTGCTCAATGCAGCGGCGGCTGTGGCCTGCGCCTCGCCAGCCTCGACCAATGCCTGCTCGTCGGTTCTGCGCTTTGCGGAATCACCGGTGGCCCACTATCTTGAGCGGGACAATGGTGACTTTATTGTCCAGGAAACGCCCAAGCATATTGTGGAGTGTGTGGAGAAGGAGGACGGTGAGTTCTCTGTGATCGAACGCATTTACCAATCCCCGCCGAGTGTCCTGCACATACACGATGACGATGAAGACgaagaggatgaggaggaggaggaggaggtggacgacgacgaccgcGAGGCTCAGCCAGAGGAGGAGGTAGACGGGGACGATGAGCGGGATGAGAATAGCCGCAGTCGCAGCCGAAATAAGACAACGAAAAAATCGCGAAAGGCCAAGCCCAAGCGAAGTTCCAAGCGCGTCacggatgaggaggaggagtttaTGAGCATTAGCAGCGGCTGCGAGAGTGACCCGGAAACGGAGCGCAAGCCCGAGTCAATGTCCACAACGTCCACAGCTCCACCTCCGCTTTGCTCAGGTCCCTCTACCAGCTCTGCGGCGGCAGCCGCCGCCGGAGCCTCCACGTCCAGCAATCTGGTGGATATCCATTCCAATTCGGCCTCCAATTCAGCCTCGAACTccacctccaccaccaccaagtCCAAAAAGAACCGGATCACAGTGCTTAGCGATGTGCCGCTCAATATGAATGAGTATCTCGATTTGATGGGTAACATAGTGGCCTCCAGTCGTATCGGGGCAGGGCGTCCCTTTGCCGCTGTGGTCCCCATTCCCCTCGTTAaggtggagaaggaggagcccCTCGACGAGTACGACGATCCCGAGGCAgcgcagcagctggagcagaagCCAAGCTTGGAGCACGGCACCACCAGTGTCATTCGCATGGCCAGCACAGTAACAGCGACGGCAACGTCGACACCGGTGACTGAAGAAGCCTCCTCCGCCGAGGACCCCAACGAGCCGCCACTCATGAAGGTCGAGGTGGAGCCCAACACGATGCTGCTCCCGCAGCGCTTCTCCACTCCTGCCCAGAGTCGCGGGCCCAAGAAATTAGTCATCAAACCAAAGGCAAcggcatcagcagcaacgACGGAGACGGCAACAAAAAAGACTGACACCACACcatcttcctcctcctcctcctcctccagcagcaACCCATCCATATCAAGAGATCTGGGCCAGGTGCAGGTTAAAAGTGAGACTCTGGAGGCTCCGGCGGCAAGCATTCTGGAGAAGCACCTAACCACCAGTCGCAGCCAGAGCCAGCACCACCATTCGGCGGTCAACGATGACGATGCCCGTGTGCTGCTGGAGTTTGCCAACTCCAAGCAGCCGCCCCCGCTGGCAGCGTCCAGTACCACGTTCGTGGTGAATGCCAGCACGGGATTCCCATCGGCAGGGTCTGTTTTTGCCAGCAGCTCCAAGACCCCATCAAAGCCTGGCGAGGAATACATTCTGCCGGACAACACCAACCTGGATGTGGATGAGATTGTGATATCCTCGTCGTCTTCCTACGCCTCCTCAGCGGCGGCCCAGGTGCAAGCAGCGCTGCAGCCTCCGGACTTTAACTTCCTTTACCACCAGACCACAAGCACGACCACTGCGGCTACCTATCCTTTTAATGCCTTCGCAcggcaacaccagcagcagccgccacacGGTGTGAGCGATGCCACCAATGCGGCCACTTTGGCCTCCTCTTCCAGCAATTCCATGGACCATGACTCTATGAATGCCTCCTTCCGGGTGGCCAAAACACAGTCGCTGCAGTGGTaccagcaggaacaggagaaTGATCCACAGATTCAGGCAGAAGGAGCCGGAGCGTCGGGTGTGTCCTCCAACCATAGCCACACCGATGTGGTGGTCAGCCACCAGCCCACCAATTTCAATGCCGCCCTGGCGGCCGTCGATTGCAGCAGCGTTGCAGCAACGCTGGACGAGGAAGCCAAGTATCTGGATTTGGACACCTGCAAGCGGGAGCAgctaagcagcagcagcaacctgcCCTCGGTCTCCGCCTCGACATCCACCACCTCGTCCTCGTTTGCCGGTGCTGCCACGGAGAGCAGTTTGGTGGGTGGACTCAACATTCGCACCGATGAAAAGATGCCCGCCAAGGGTGAGATCTCCGAGCAGGAGAGCAACTGTGACATTGAAAACTCTTGGAGTGAATCGGTTTATGGGGACATTTCGCAGAGGTTTTTCAGAAACCAGTTCTCTGGAGGCTACAACCCCGATTGGCGACAGGACTACTACCCGGCTCAGGATCTCAGCAGCGCTCAGCAGAGGGAGCATAAGCGCTTCGACTTTAATGCGATTGATGATGAGGCCTCATCCAGCTCTAGGAAGAGCCAGCTGACGGATATCGTCCCCAATGTGGCCACCTCCTCCACTTCCACGTCATCGGCTTTGCTGGCGGGTCCACCAATAGCTTCGACATCTAGGGCTGCCGCTGAGGCGGCAgcggaggcggcggctgctCTTGCCCAGCGAAGGCCACATCGCCGCAAGCTTTACAAGTGCCCCCATTGCGATTCCATCTTCGAGAAGCTCAAGGAGCGGAATGCCCACATGATAAGCGACCATAACTATGTGCGTCAGAATCGAAGGCTCATTTGCACCCAGCCGCCGGTCAGTGAACCGATGCTGcccccgcagcagcagcagcatgcccagttgctgctgcaaacCGACGACGCTGTGCAGGAGGACTCAAAAGATGGCATTGTGAAGATCAAGCAGGAGCAGTGTTTGGAAAAACCGGAAGTCGAACAACTGCACCACGCTAATTCGGCTGAGCTGCTGTCGGATGTCAAGGACTCGGAGCTTCTGGGTATCGGCGGCGAGGGCGATGCGGATTTAGATGGCGATATTAAGCCACCTAGCCAGCTATTTGAGAAGTCGTCGTCCACACTGCCGCCGCTGGCCATGACCACGCCGGCAGCAAAGCTGGCGGCACTCTATCGCATGCTTATCGCCTACAATGAATCGAAGCTGGGCCAGGAGCGCAACAACCTTAGCGAACTGGAGCAGAAGGCGATGGAGAAGTCCATCTTTCTGTGCTACGTCTGCCGCACCGACTTTCCCTCCGTGAAGCTTTACGACGCCCATCTAACCGAGCACCCGGCCGAGTGTTTCACCTGTGGCAAGAAGTTCTATCGCTGGAAGAACTTCTCTCTGCACCTGAAGAGGCATCTGGGCTGGAAGGAGTTCGGCTGTTACGTGTGCGACAAGAAGTTTGTGGTACGGAGCGCCCTGGTCGAGCACATGCGGATGCACACGGGTCAGACGCCGCTCAAGTGCAAGATATGCGGGAAAAAGTTCAAGCGCTACTCGAATCTGACGCAACACCGCAAGCGGCACACCAAGGTGATGGTGCGAAAGAAGGAGTATGTGTGCCACTGTGGCGAGGTTCTGCCCTCAAAGGCGCGCTTCCTCTGGCACAAGGAGACCCACGACCTGAAACCGAAATGCTGTCCGTATTGCTGTGACCGATTTGTGCACGCCAACTCGCTGCGCCGGCACATCCGGCTGGCGCACTCCGACAAATTTGACTACGCCGAGCCGATGGAGTGCCCCATGTGCAAGCAGATCTTCGCCAAGACATCGATCAAGGCCCACATGGCCACGCACTCGACGGAGCCGCAGTACGACTGCGCCATTTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATCCACTCGTGGGTCCACGCCAATCGGACGGCCAAGCCCTTCAAGTGCGAATACTGCCCGAAGGCGTTTGTGCGTGAGCTGGACTTCAAGAACCACATCAATGCCCACAAGCAGATCAAGCCGTATACGTGCGAGTACTGCGGCTGCAAGTTTATCCGCAAGTACAACTACATGCGGCATCGTCGCGAGCACCACGGCACCAAGAAGTTCACCTGCGACCAGTGCGACAAGTCCTTCCATCGGCACTACTATCTGATCGAGCACCGGCGCATGCATACCGGTGAGCGACCCTTCACCTGCACCATTTGCGGCAAGAGCTCCACCACCAAGACCAACCACAACAAGCATCTGAAGATCCATCATTCGCGCGACCCCTTCACGGTGGAGGTCTAA
- Protein Sequence
- MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGGGGNNSMGSALAAAMMSGGGGGGGGSDGGEASLADDKSAFTLSPQCGDVKPVVATSPPAMSKTISAAMPVVPPAPPPLPPLSSANAAPSCTSPSASSSTSSSSNLSNPPMKALKCAPPTTEARANTSAHPTISSVSTQYQPSLVAPDYRFNHQQQQQQSGFGRGVAGTNAATLVIPQVAQQHFLASHQQQAHFTHQQQQQQQQQSPLKFTYATALPPPPPLQLFTQQQQQQPTAASTQPHQKPPPAYGAAISQIRSQHNQIKQQQPHQQQLQQQQSQPPHMAGQHNLTLAPPTPTAEVAGKQPSKAHAEVFLNPPPPPPPPSQAQATVSIHSMGQNHQSHPHLQQQIHQQQQLTTSPSSRLQQQQQSLSLQTYGPVSVSSSCSSSSASNSGSAAAASGSRSSRQTNSPFGALLNAAAAVACASPASTNACSSVLRFAESPVAHYLERDNGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDEEDEEEEEEVDDDDREAQPEEEVDGDDERDENSRSRSRNKTTKKSRKAKPKRSSKRVTDEEEEFMSISSGCESDPETERKPESMSTTSTAPPPLCSGPSTSSAAAAAAGASTSSNLVDIHSNSASNSASNSTSTTTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGAGRPFAAVVPIPLVKVEKEEPLDEYDDPEAAQQLEQKPSLEHGTTSVIRMASTVTATATSTPVTEEASSAEDPNEPPLMKVEVEPNTMLLPQRFSTPAQSRGPKKLVIKPKATASAATTETATKKTDTTPSSSSSSSSSSNPSISRDLGQVQVKSETLEAPAASILEKHLTTSRSQSQHHHSAVNDDDARVLLEFANSKQPPPLAASSTTFVVNASTGFPSAGSVFASSSKTPSKPGEEYILPDNTNLDVDEIVISSSSSYASSAAAQVQAALQPPDFNFLYHQTTSTTTAATYPFNAFARQHQQQPPHGVSDATNAATLASSSSNSMDHDSMNASFRVAKTQSLQWYQQEQENDPQIQAEGAGASGVSSNHSHTDVVVSHQPTNFNAALAAVDCSSVAATLDEEAKYLDLDTCKREQLSSSSNLPSVSASTSTTSSSFAGAATESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRFFRNQFSGGYNPDWRQDYYPAQDLSSAQQREHKRFDFNAIDDEASSSSRKSQLTDIVPNVATSSTSTSSALLAGPPIASTSRAAAEAAAEAAAALAQRRPHRRKLYKCPHCDSIFEKLKERNAHMISDHNYVRQNRRLICTQPPVSEPMLPPQQQQHAQLLLQTDDAVQEDSKDGIVKIKQEQCLEKPEVEQLHHANSAELLSDVKDSELLGIGGEGDADLDGDIKPPSQLFEKSSSTLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKVMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00491690;
- 90% Identity
- iTF_00489545; iTF_00527501;
- 80% Identity
- -