Basic Information

Insect: Drosophila leontia
Gene Symbol: ken1
Assembly: GCA_008042735.1
Location: VNKB01017891.1:62563-64659[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 5e-05 0.0043 17.5 2.2 2 23 197 218 196 218 0.97

2 12 0.0043 0.37 11.4 0.1 1 23 224 249 224 249 0.91

3 12 0.01 0.87 10.3 0.1 3 23 258 281 256 281 0.93

4 12 0.00086 0.074 13.6 0.4 2 23 294 315 293 315 0.96

5 12 8.4e-06 0.00072 20.0 0.6 1 23 322 344 322 344 0.98

6 12 0.0081 0.69 10.6 0.2 1 23 350 372 350 372 0.98

7 12 0.014 1.2 9.9 4.0 1 23 378 401 378 401 0.97

8 12 0.009 0.77 10.4 4.0 1 23 407 429 407 429 0.96

9 12 0.00076 0.065 13.8 2.9 2 23 436 457 435 457 0.96

10 12 0.00025 0.021 15.3 1.1 3 23 546 567 544 567 0.95

11 12 0.0096 0.82 10.3 0.7 1 19 573 591 573 595 0.95

12 12 8.8e-06 0.00075 19.9 1.2 1 23 601 623 601 623 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	5e-05	0.0043	17.5	2.2	2	23	197	218	196	218	0.97
2	12	0.0043	0.37	11.4	0.1	1	23	224	249	224	249	0.91
3	12	0.01	0.87	10.3	0.1	3	23	258	281	256	281	0.93
4	12	0.00086	0.074	13.6	0.4	2	23	294	315	293	315	0.96
5	12	8.4e-06	0.00072	20.0	0.6	1	23	322	344	322	344	0.98
6	12	0.0081	0.69	10.6	0.2	1	23	350	372	350	372	0.98
7	12	0.014	1.2	9.9	4.0	1	23	378	401	378	401	0.97
8	12	0.009	0.77	10.4	4.0	1	23	407	429	407	429	0.96
9	12	0.00076	0.065	13.8	2.9	2	23	436	457	435	457	0.96
10	12	0.00025	0.021	15.3	1.1	3	23	546	567	544	567	0.95
11	12	0.0096	0.82	10.3	0.7	1	19	573	591	573	595	0.95
12	12	8.8e-06	0.00075	19.9	1.2	1	23	601	623	601	623	0.98

Sequence Information

Coding Sequence: ATGGGTACCAAGGAGCTGCAGTACTCCGTCCACTCACTGTGCCGCACCTGTCTGGCCCACCTGGAGCAGGGAATGGGCCACGACCTGTTCCTCATTCCAGATCTGGCCAAGAAGCTGACTGTTTGCACGTCTCTGGAGGTGGATGCCCAGGATGGCTTTCCACGCCACATCTGCCACCTGTGCTATGGAAAGTTGAACGAGCTGCACGATTTCCAGGAGCAGTGTGTGGGCTCCCAGAAGCGATTCAAGGAAATGGTAGCCAACAGCCAGGTCTTTCCCGTTGGACAATTCGAGCCCGTGGCGGAGGCAACAGAAGCACCGAGCAGGCAAGAGGAGCAGGCCAGTTATGATCCTCTCCTCAACCACAAGCTGGAGATGATTGACAATGAGGAGGAGGTGTTTAAAATGTTGGAAACAGTGGACAGGGAACCAGAAGAGCATTGCCAAGAGAATTCCTCCAGTGAAGAGCCTGAACAGGATGAGCGGAATGAGCAGGAGGCGCCGAAGAGCTTCTCCAGCGACGACGAACAACCCTTGGCAATGTGTAGGAAGACTGCCTGCCAGGAGCGTCGCCCGCATCACCTCATCACCTGTCCCATCTGCCAGCAAAAGTTCAAGAAGCCGTCGAAGTACGAGGAGCACATGAAGCACCATAATGACCTGCTGCCCTTTCAGTGCGCGGAGGATAACTGCCGCAAAGGCTTCACCACGGCAGGTGCCCTGCGGCTGCACGTGGACTACGCGCACACCAAGAAGGCGGATGAGATTCCCTGTACCGTAGAGGGCTGCCGGTTGATGTTTCCCCGCCTTCGCCTGCTAACGATCCACCTGAAAAAGGTGCACAACCAGGTCAGGGTGAGTGCTCCGCGGGCCGATCAGCCGTGCGGGGAATGTGGCCTGGTCTTCCGCTGTCCGGTGGCCCTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCGTATCCCTGCAACATCTGCGGCAAGGGCTTCCACATCAACAGCGCCCTGAAGAATCATCTCCTCCGCCATGCGGGCATCAAGAACTACGTGTGTCCCTACTGCGGCGTTGGGAAAACAACTCGCCAGGAGTGGAGCAAGCACCTCCTCACGCACACCCAGGAGAAGCAGTTCAAGTGCCACATTTGCGACCATGCCACCCACACCAAGCGCGCCCTGGACAGTCATGTGAAGATCGTGCACGAGAAGATCCGGAACTTTGCCTGCCAGTACTGTGGCAAGACCTTTGGCAAGTCGCATGCCTGCAAGATCCACGAGATGACGCACACGGGGGAGAAGCGGTGCGAGTGCAAGGTGTGTGGCAAGAAGTTCCTGTACACGGAGAGCCTGACCAAGCATCTCAAGATCCATGAAAAGAGTGTGGAGAGAGCCCTGGAAACCTATCGCCAGCGGCAGGGAGACTGTGAACCCGGGGAAGTCCAGGTGGATGCCGATCAGCTGCTGAAAGTGTGCGCCGAATCGGTGGCCACCATACCCAAAGACCCGCGTCGCGTGGAGCGCGTTGAGCTGTCCCAACTGGCAGGCACAGTGGTTAATCCCATTCCCACGGTTCAACTGCCGCCCAGCGAGCCCCCAGTCCGCACGAAATTCGTCCAAAAGGAGGGCATGCACCTTTGCCCCGGCTGCAGCCAGGGATTCAATAACCTCGGCAACATGAAGCGTCACTACAAGAGTGTCCACGAAAAGGTTAAGGACTTTGAGTGCCGCTTCTGCGCGCGTCGTTTTGCCAATTCGCAGTCCCTGAAGCAACACGAGTGGATACATACGGGTGAGAAGCCGTACGAGTGCAAGGTGTGCAGCACTCATTTCCGCCAGGAGGCGGCTCTCATCCGCCACCAGAAGGTACACTACGAAAAGCCAGCCAAGCCGCCGAAACCAGCCAAGGAAATCACGTATAAAGCTCGCCAAAAGGCAATGCAAAAGAGTGAACGCAGACAGAAGGTGGAATCGCTGCGCCAGGAGATAGCCGAGGCTGCCAAGGAGGAGCTCAAGGATCTGGCCAAGCTAAGGACACTAGAGAAGCAGCAGAACAGCTATGAACAGTATCAGGCAAAGGCAGGGGAAGGGGAATCTTAA
Protein Sequence: MGTKELQYSVHSLCRTCLAHLEQGMGHDLFLIPDLAKKLTVCTSLEVDAQDGFPRHICHLCYGKLNELHDFQEQCVGSQKRFKEMVANSQVFPVGQFEPVAEATEAPSRQEEQASYDPLLNHKLEMIDNEEEVFKMLETVDREPEEHCQENSSSEEPEQDERNEQEAPKSFSSDDEQPLAMCRKTACQERRPHHLITCPICQQKFKKPSKYEEHMKHHNDLLPFQCAEDNCRKGFTTAGALRLHVDYAHTKKADEIPCTVEGCRLMFPRLRLLTIHLKKVHNQVRVSAPRADQPCGECGLVFRCPVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHLLTHTQEKQFKCHICDHATHTKRALDSHVKIVHEKIRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGDCEPGEVQVDADQLLKVCAESVATIPKDPRRVERVELSQLAGTVVNPIPTVQLPPSEPPVRTKFVQKEGMHLCPGCSQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYECKVCSTHFRQEAALIRHQKVHYEKPAKPPKPAKEITYKARQKAMQKSERRQKVESLRQEIAEAAKEELKDLAKLRTLEKQQNSYEQYQAKAGEGES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548237;
90% Identity: iTF_00524573;
80% Identity: -