Basic Information

Insect: Drosophila leontia
Gene Symbol: hang
Assembly: GCA_008042735.1
Location: VNKB01010923.1:11301-24914[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.3 26 5.6 1.0 3 23 601 622 600 622 0.93

2 19 0.96 83 4.0 3.1 3 22 730 749 728 749 0.89

3 19 0.00064 0.055 14.0 3.3 1 22 866 887 866 889 0.90

4 19 0.074 6.3 7.5 0.1 2 21 901 920 900 921 0.93

5 19 0.00074 0.064 13.8 0.2 2 23 1056 1078 1055 1078 0.95

6 19 0.0021 0.18 12.4 0.1 1 23 1086 1109 1086 1109 0.96

7 19 1.7e-05 0.0015 19.0 0.1 2 23 1196 1217 1195 1217 0.97

8 19 0.00031 0.026 15.0 2.9 2 23 1299 1321 1298 1321 0.97

9 19 0.024 2.1 9.1 0.2 2 23 1330 1352 1329 1352 0.95

10 19 0.0023 0.2 12.3 0.1 1 23 1365 1388 1365 1388 0.97

11 19 0.00013 0.011 16.2 1.1 1 23 1446 1468 1446 1468 0.99

12 19 0.0021 0.18 12.4 0.9 1 23 1476 1499 1476 1499 0.96

13 19 0.81 70 4.3 0.3 2 19 1507 1524 1507 1525 0.93

14 19 3.4e-05 0.0029 18.0 1.4 3 23 1621 1641 1620 1641 0.98

15 19 0.0054 0.46 11.1 0.1 1 23 1676 1698 1676 1698 0.97

16 19 0.00063 0.054 14.0 0.6 2 23 1787 1809 1786 1809 0.93

17 19 0.59 50 4.7 0.1 2 20 1829 1847 1828 1849 0.91

18 19 0.007 0.6 10.8 0.4 3 23 1864 1884 1864 1884 0.98

19 19 0.00011 0.0093 16.5 2.1 1 23 2207 2229 2207 2229 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.3	26	5.6	1.0	3	23	601	622	600	622	0.93
2	19	0.96	83	4.0	3.1	3	22	730	749	728	749	0.89
3	19	0.00064	0.055	14.0	3.3	1	22	866	887	866	889	0.90
4	19	0.074	6.3	7.5	0.1	2	21	901	920	900	921	0.93
5	19	0.00074	0.064	13.8	0.2	2	23	1056	1078	1055	1078	0.95
6	19	0.0021	0.18	12.4	0.1	1	23	1086	1109	1086	1109	0.96
7	19	1.7e-05	0.0015	19.0	0.1	2	23	1196	1217	1195	1217	0.97
8	19	0.00031	0.026	15.0	2.9	2	23	1299	1321	1298	1321	0.97
9	19	0.024	2.1	9.1	0.2	2	23	1330	1352	1329	1352	0.95
10	19	0.0023	0.2	12.3	0.1	1	23	1365	1388	1365	1388	0.97
11	19	0.00013	0.011	16.2	1.1	1	23	1446	1468	1446	1468	0.99
12	19	0.0021	0.18	12.4	0.9	1	23	1476	1499	1476	1499	0.96
13	19	0.81	70	4.3	0.3	2	19	1507	1524	1507	1525	0.93
14	19	3.4e-05	0.0029	18.0	1.4	3	23	1621	1641	1620	1641	0.98
15	19	0.0054	0.46	11.1	0.1	1	23	1676	1698	1676	1698	0.97
16	19	0.00063	0.054	14.0	0.6	2	23	1787	1809	1786	1809	0.93
17	19	0.59	50	4.7	0.1	2	20	1829	1847	1828	1849	0.91
18	19	0.007	0.6	10.8	0.4	3	23	1864	1884	1864	1884	0.98
19	19	0.00011	0.0093	16.5	2.1	1	23	2207	2229	2207	2229	0.98

Sequence Information

Coding Sequence: ATGTGCGACGCTGCGGCAACGGCGTCGGAGACGGCGACCACGGCGCTGCTGGCAGGAGTTAGTGCAGTGACGGTGCCTGGGGCTGGAACACCGGGAGCAGCTGCCCCCAGCACAACTACATCCACATCCCAGCCGGAAGCTTCggcgacagcaacagcaaccacgatgacgatgacggcGGCGACGACGCCGCTGGCGACGAAGAGCGAGCGGGCGGCGCGACAAAACTGCTGTCGCCTGTGCATCGCTCCGGCCACCGAGTGCATCTCGATCATCAACAGCTATGCAGCGGACAAGGAGCCGCTGTCCACCAAGATCCACAACTGCGTCAGCATCAAGATCACCGCCCAGGATCGACTGTCGCTGCATATATGCCACGCCTGCATCAGCTACCTGAACTCGTGGCAGAGCTTCAAGAACCGCTGTCACAGCTCACAGACAAAGCAGCGCCAGTGGCTGGAGACCAGCAACAAGAGCAAGCTCTTCAACTATCTGGACCTGAACAGTGCCGAGAACGGTGGAGCCTCCTCCgatcatcagcatcaacagcattCGCAGGCGGCGCATCAACCGCAATCGGAGAATGAGCTTGACGCAGAGAAGGCGATGGCACCCGCCACAACGGCCGCCAACATATTGGATGGCATACCATCGCTGAAGAAACGCAAATCCCTAACAGTCTATGTGAGTCCTAAACCGCAACAGCTGCCGCAGCATCAATTGCAGCAGttacagcagcagctgcagccacCGGCGGCCAGATTGACGTCGACGGCGACCGGCAACAACGCGCAGCAAACGTTGCAGACCCTTCTCCTGCAGGTGCCAGCATCGACGGCGAGCTCCTCTTCCActatcaccaccaccacttcTGTATcccagcagcgggagcagcagcatcagcgcCAGCAGTCGCATCAGTATCGCAGataccatcaccatcatcatcatcagcagcagcagcagcaacatagtcagcagcagcaacagcagcggagCAAGCAACACcatcatcagcaacagcagcagcagcaacaccgaCGCCACCGTCAGTTTCGTCCTCAGAGGCCAACAACGGTGCCGGTACCGAATCCGGCTCCATCGTTGCGCAAATACAAACCCAAACTGTACTTGCCATTGGATATAGCAGTGCCACCACTGCCACCGCTGCCATCAGTTGCTCCGGGATCGATTGCTGCTTCCGCTTCTGCGTCTGCGTCTGCCCCTGCACCTGCTGGCGTTCCTGCTGCTGAACAGCCGCTGCTTTCGGGATTCTCCGGTTCTCTAACCGGAATTGCTGGTGTGGGTGGTGGAATGGAGAGCCTGTCATTGTCGCTGCCACTTGATTTCAGTCAAAGCTGCAGTAGCGGTCACGTCCAACAGACTGGTCTGTTGCCCCTGGCCACggccacagccacagctacGGCAAcgtccacgtccacgtccaATCCTACGGGCATCGCGTCAGCCACTGCCACTTCTGGCACTGGCTCTGCATCTGCAACAGCATCCGTGTCCACGGCTCCGCTGCTCATGCCGCCGCTGCCAGCGTTGCCCATCAAAGATGAGCCCATTGACACGGACGATGACTACCAGATGAAGATGATAGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAGCGTTCCGAGCACGAGGGCGATATGCCGTTAATGGCCTCGGAATACGACTATACGGCCCAGCATGGCGTTAATGCCCATTCTTTGGCCGCCGGCCTGCCACCGAATGCTGTGGCCAATGTGGCCGCCGCCGGGGATTCCAAGGTGGCCAGCTGTCGTGCCTGCAGCCTACAGTTCTCCACCCGAGCGAATGCCCGTCGACATGAACGGAATCTGCACCCGAACCTCTTCCAGCTATCCACGGACTCGCTCCACAATACGTCAGTTACAAAGCCAACGCCAGCCTTGGCCGCCGCATTGGAAATTCAACgggcggcagctgcagcggccaCCGCAGAGGCGAATCGTGCTGTGGGCGCTGCCGGTGGTAATATCACTCCACAGAAATACCGTCAGGTGGTGATGAATGCATTCATCAAATGCGAGGGCGGCGGCTATGACTATGACAATCCGGAGCAGTACCGTCCACTGCTCACCCACGACAAGGTGGAGTTCATCGAACAGAACGAGGAGTTTCTCGAGCAGTACCAGACGATgacctgccgctgctgcagcaagTACTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGCTGCTGCCGCGCAATCTATGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCATCTGAAGAAGCGCAACTGCATAAATCTCTACAGGGTTTTAAATACGCTGCGTGGCAAGACCCCAGTGCTACCCATCTCTGCCACGGATGCGGATGCAACTGAGGCTGCTGACGACGGAGTCACAGCCACAGCTGTAGCGGTGGCAGATGCCGCCGGAGCAGGTGCTGTCACAATGGCCAGTCCCACGGTGACCATTAGTGGAGAGACTGCCGCTACACCCGGTGAACGTCCAGAGAAGCTGCGCGccaaggagctgctggtgAACAAGCTATACGAATGCAAGCTCTGCCCTAAGGGATTCCGCACCAAGCACGAGTTCCGCACCCATGTCTACGACAAGCATGCGGATGTCCAGCGCAAGGACAACAACTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCGGTGGACAGGCGCCGGCACTACAACAACATGGACTGCATTGTCCGATTGCGCTGCATGACGTGCGATGCCAAGCTGGAGACGCACCAGCGATTCCTCGATCACGTCTACCAGGATCATCTGGGCGGCGTGGGCGGTGGCGCTGGCGGTGCCAGTAGTGATAATGCCTCCACAACGGGTAGCGGCCTGGCCAGGAGCAACAGTATGGAGCATTCGCCGGGCAAAAGGAGTCTGCTCGGTGCCCTGGGCATTGGCGTTGGATCATCGGCGGAAGAATCGCGCAGCAGCAGTGTGGCGCCCACGCTAACATCCACGCCCAAACCAGCGGGAGGAGGCACAGCCACAACGGCCTCCTCAGCCTCCGCGCCCAGTTCATCGAATCGTGGTGATGCGGCCGCACCCAAGTCCCAGTACTTTTCACGAATGCCACAGGTGTGTCCCATTTGCGGACAGCAATACAATAACTACAACAACGTGCTGCGCCACATGGAATCGAAGCATCCAAACAAGCTGCCCGAAACGTACAAGTGCGTACGCTGCGGCCTGGGCTATCCGCGGATCTCCTACCTGCGAGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGTCACTCGGGCGGCTTCGAGTACATTGTGAATGCGGATGCCGTTAAGCTGGCGGACGGCAGCACGCCGAATGTGTACACGGGTCGCTTCGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACCCTCGATGAGGACGATGAGGAGGCAGCGGGTAGCATGGCCAAGAAAATGCGACTcgacgacagcagcaacaacagcagcttgGCGGGCGtggccagccagcagcagaaggagtgTCCCATCTGCAATGCTGTGTTCAGCAACAACATTGGCCTCTCCAATCACATGCGCTCCCATTACACAGCCGCCAGTGTGGTGACCGCAGCTCTGGCGGCGGCCAATCGCATGACACCCAAATCACTGACCATAACAGCAACACCAGCGACAACGACGGACGCAAGTCCAGAGGCAGAGGCATCGGCCCCGGCCATGACCAGCAGCAATGTTGTGCCACCGGCGATGGCAAATCAAACGCCCCAGGAGCAGGCCGTATTCCGGCGAAGTTTGGATCAGGCGGCCGATCGTCGCTTCCGGCGAATGCGTTGCCGTATTTGCCAGCGGCGCTTCAGCTCAAAGAAGTCCTATCGCTACCACATGCTGACAGACCATCAGGTGCAGAATGTGCAGTTCATCAAATGCAAGCTGTGCAACGCGGAGTTTGCCTACGAGAAGGGTCTGAAGGTGCATCTGTTCAAAGTGCATGGACGGGCGATCAAGGATGAGATGATTATCAAGCAGTTTGAGTGCGAGGTCTGCTCGATTGTATACAgctcggagctggagctgcagcagcacaagCGGAGTGTCCACAAGCTGAcctcggcatcggcatcggttTCTGCTTCAGCCTCGGCATCCGCCTCCACTTCTGTCAAGATGGAGGACGATGTTTTGATGGACGAAGAGGTCAAGTCAACAGCCGATCTGTCCACCCTTTCGGCCAACGCCTCGGGACTGGGAGTGGGCACACCGCTGTACTGGTATCAGTGCAAATACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATTCACATTAACTCGCATGACGAGTTCGACTCGAATGATTACTCCTGCAAGGATTGTGGCAACGTCTATAGCGGACGCAAGAGTCTATGGGTGCACCGGTACAAGAAGCATCCACAGGTGCCCGACCCGGCCGAGTGCTCGCTGTGCCGCAAGATCTTCTTCGATCGCCAGATGCTGGACAATCACACGCCCACCTGCAACCGCAAGCCCATCACCTCGACGGGtgcccaccagcagcagcagcagcagcagctacagcagCAGGATTcattgcagcaacagcaggcggcACTGCAAAGGGCCGTTTTCAGGCACAAGACGggcgacgatgatgacgaggaggatgatggccggcagcagcagcagccgctggaGGAAAGCGATAGCAATGGGGCGGCAACAGcgtcggctgctgctgcagcagtggcagctTCGGCCCAGGCTGCCCTGAAGATACGCATTCCGGAGGTGGCCTGTACCATTTGCGGGGCCCGGTTCACCGATCAGGAGCACTTTAGCAAGCACATCCAAAAGCACGAACAGGAGCTGTATGTGGATAATCCGCTGGCGGCGATGTTCGATGATGGGCCGGCGGATGCTGGCCAGTTCCAGGTTGAGCGGCAGAATGAGAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCACActaccagcaacaacaacaacaacagcagcaacaactcgATGCTGCACCTCCGCGAGCTGCATGCAGTGGGCCTGATGCccaaccagcagcaacagcagctgcagcaggaacagcagagccgcagcagcaacaacaacaacatgaacCACAGcggcgggagcagcagcagcaagtcaATGAAGCGGAAGCGTGAGCTTAAATGCGAATACTGCGCCTCCACCttcatcagcaacaacaatctgCGCCGGCATATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTCCCAGAGCCACCAATTATCCTGGTGGACGATCATCTACAGTGCCGTCGCTGTCAGCTCAGTTTCGAAACGAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCCAAGGTGGTGCGTCCCTTCTGCCCCTTCCAGTGGGGCTGCGATCTGTGCGGCGAGTATCTGTCGCGAAAGGAGAAGCTAATGAATCACATTAACAATCATCTCAAGGAGGAGGTCATTGTCCCAGTGGCCACCAAGGCGGCCATTAAACGcgaagcggcggcggcaacggcaacagcagcgaCAGCTGCAAATACGGCGGAATTAACAGCAGATGAGGGAGTAGATCAAGATCGGGAGAACAAGGCTCGGGGCAACAAAGATAAGGCAACGACGGCGGTGGTGGCAGGTGGACAAAAAGATGTAGAAAGCGATGACCTGGACGAGGAGGATAGCTccggcgaggaggaggaggaaagtTCAGGCACGGGAGACGATGAGGACGATGAGGAAGATGACTCGGAAGATGACGAGGGCGATGGTGGCGAAGGTGAAGACGAGGAGGGTGTGCAGCCTGGTCAGCTGTTGactcaacaacagcagcagccgcagcagcagcacaaccaGGATGACGATGACCTGGTCGAGGAGGTCAATAGCTCGGATGACGAAGATGATGGCGAGGTGGagagcgacgacgacgacgacgatgtcGGGGAGGATGACGATGAAGGGGATGTTGACGATGAGGATGACGATGTGGAGGAACCGGAACCGGTGGCAGTGGCTCAACCCCTGATGAATGGCAATGGCAAGTCAAAAATGCCGCCACTTATCATGCCCAGTTCcgacgacgatgaggatgTGGATGATGGTGTTATGCCCATCGATGACATTATTGAAGAGGAATTCGATGAAGATGAGGCCGAGCCAGATGCCGATCCCGATCCGGATGTGGATGATGCCATCGAGGAGGTGGATGACGATGATTTGGATGaggatggagatggagatgatgtggaaatggagatggaggtggagatggaggaggaggtggtatCGGCAGCCTCCTCCTCGGAGAGCGAGTCCTCGTCAACGACCAcgtccaatacgcattcgcattcgcattcacaTTCCACGGGTGAGCGGCGTAAGAAGAGGGCTGACGATCAGTTGAATGATCCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTCCAGAGCCACATCAAAAGCCATTTTCTCAATGGGCCAAAGCTCACAGtggcatcagcagcagcaggcagcaaggCGGCGTCACTAGCAACCACAACggcggcaccaccaccagccaAGACGAAGCCTGACTCCAAGTCGGCCCtgctggccaacaacaacaataagagcAGCAAGactgttgcagctgcagctgcagctgccacaAACTGA
Protein Sequence: MCDAAATASETATTALLAGVSAVTVPGAGTPGAAAPSTTTSTSQPEASATATATTMTMTAATTPLATKSERAARQNCCRLCIAPATECISIINSYAADKEPLSTKIHNCVSIKITAQDRLSLHICHACISYLNSWQSFKNRCHSSQTKQRQWLETSNKSKLFNYLDLNSAENGGASSDHQHQQHSQAAHQPQSENELDAEKAMAPATTAANILDGIPSLKKRKSLTVYVSPKPQQLPQHQLQQLQQQLQPPAARLTSTATGNNAQQTLQTLLLQVPASTASSSSTITTTTSVSQQREQQHQRQQSHQYRRYHHHHHHQQQQQQHSQQQQQQRSKQHHHQQQQQQQHRRHRQFRPQRPTTVPVPNPAPSLRKYKPKLYLPLDIAVPPLPPLPSVAPGSIAASASASASAPAPAGVPAAEQPLLSGFSGSLTGIAGVGGGMESLSLSLPLDFSQSCSSGHVQQTGLLPLATATATATATSTSTSNPTGIASATATSGTGSASATASVSTAPLLMPPLPALPIKDEPIDTDDDYQMKMIDESDDMVDPTMFLERSEHEGDMPLMASEYDYTAQHGVNAHSLAAGLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSLHNTSVTKPTPALAAALEIQRAAAAAATAEANRAVGAAGGNITPQKYRQVVMNAFIKCEGGGYDYDNPEQYRPLLTHDKVEFIEQNEEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNTLRGKTPVLPISATDADATEAADDGVTATAVAVADAAGAGAVTMASPTVTISGETAATPGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGAGGASSDNASTTGSGLARSNSMEHSPGKRSLLGALGIGVGSSAEESRSSSVAPTLTSTPKPAGGGTATTASSASAPSSSNRGDAAAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRFDYVMKDLMSITNGGTLDEDDEEAAGSMAKKMRLDDSSNNSSLAGVASQQQKECPICNAVFSNNIGLSNHMRSHYTAASVVTAALAAANRMTPKSLTITATPATTTDASPEAEASAPAMTSSNVVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSELELQQHKRSVHKLTSASASVSASASASASTSVKMEDDVLMDEEVKSTADLSTLSANASGLGVGTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKIFFDRQMLDNHTPTCNRKPITSTGAHQQQQQQQLQQQDSLQQQQAALQRAVFRHKTGDDDDEEDDGRQQQQPLEESDSNGAATASAAAAAVAASAQAALKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTSNNNNNSSNNSMLHLRELHAVGLMPNQQQQQLQQEQQSRSSNNNNMNHSGGSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPIILVDDHLQCRRCQLSFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKAAIKREAAAATATAATAANTAELTADEGVDQDRENKARGNKDKATTAVVAGGQKDVESDDLDEEDSSGEEEEESSGTGDDEDDEEDDSEDDEGDGGEGEDEEGVQPGQLLTQQQQQPQQQHNQDDDDLVEEVNSSDDEDDGEVESDDDDDDVGEDDDEGDVDDEDDDVEEPEPVAVAQPLMNGNGKSKMPPLIMPSSDDDEDVDDGVMPIDDIIEEEFDEDEAEPDADPDPDVDDAIEEVDDDDLDEDGDGDDVEMEMEVEMEEEVVSAASSSESESSSTTTSNTHSHSHSHSTGERRKKRADDQLNDPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKLTVASAAAGSKAASLATTTAAPPPAKTKPDSKSALLANNNNKSSKTVAAAAAAATN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00478146;
90% Identity: -
80% Identity: -