Dleo007160.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila leontia
Gene Symbol
-
Assembly
GCA_008042735.1
Location
VNKB01007301.1:41152-45548[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0016 0.14 12.8 1.5 1 23 208 230 208 230 0.96
2 25 1.5 1.3e+02 3.4 3.7 1 21 237 257 237 259 0.84
3 25 1.2 1e+02 3.7 0.9 2 23 291 312 290 312 0.93
4 25 0.00012 0.01 16.3 2.1 1 23 385 408 385 408 0.94
5 25 3.2 2.8e+02 2.4 2.4 1 23 449 471 449 471 0.91
6 25 0.0053 0.46 11.1 0.0 2 23 483 504 482 504 0.96
7 25 0.00092 0.079 13.5 1.2 1 23 582 605 582 605 0.96
8 25 0.0065 0.55 10.9 0.4 2 22 616 636 615 636 0.93
9 25 1.1 97 3.8 5.6 1 23 645 667 645 668 0.94
10 25 0.0016 0.14 12.8 1.9 2 23 687 708 686 708 0.97
11 25 4.3e-06 0.00037 20.9 4.3 1 23 715 737 715 737 0.98
12 25 0.014 1.2 9.8 0.9 1 23 868 891 868 891 0.91
13 25 0.0021 0.18 12.4 1.1 1 22 898 919 898 919 0.95
14 25 0.0086 0.74 10.5 2.0 1 23 928 951 928 951 0.95
15 25 7.5e-06 0.00064 20.1 2.0 1 23 969 991 969 991 0.98
16 25 8e-05 0.0069 16.9 0.4 1 23 998 1020 998 1020 0.98
17 25 0.076 6.5 7.5 0.0 2 21 1047 1066 1046 1067 0.92
18 25 0.0031 0.27 11.9 2.2 1 23 1113 1136 1113 1136 0.96
19 25 0.0042 0.36 11.4 0.9 1 23 1173 1196 1173 1196 0.96
20 25 0.00095 0.081 13.5 1.3 1 23 1222 1245 1222 1245 0.97
21 25 4.7e-06 0.0004 20.7 0.2 2 23 1272 1293 1271 1293 0.95
22 25 0.0016 0.14 12.8 3.3 1 23 1299 1321 1299 1321 0.99
23 25 1.9e-06 0.00016 22.0 2.0 1 23 1327 1349 1327 1349 0.97
24 25 1.6e-07 1.4e-05 25.3 2.4 1 23 1355 1377 1355 1377 0.99
25 25 0.00061 0.052 14.1 0.1 1 21 1383 1403 1383 1407 0.91

Sequence Information

Coding Sequence
ATGCTTCCCCCAAACATTTGTCGCACTTGTGCGGTCCAGAACACGGATTTACGGCCACTGTCCACCTGTCTGGCTAAAGACGCCTCAAAAAGTTTCTATGATGTGCTCCAGGAGCTAACACAAATCGATCCCCTGGTTGAGAGCTCGGGTGACAGTCTGCCGCAACATCTCTGCACCGAGTGCCTGGCGAGATTGGAAAGTGCCTATGCTTTTGTGGAACAGGCCAGAAAAGTCAATGGCGAGCTGTTGGTTCGCCTGCGGGAATGCCTCGATGAAATGCCCATTGACATTccgcaggaggagcagcataTCAAAACCGAAGTAGACATCGATGAGGCGACTCCCAAGTTTGTTGTGGATTCCCCAGGAATATCACCTGTGGAGTTCAAATGGCAGCCGGAAAGTGACAGTGATGAGGAACCTGCTGAAGCAGCAGTCAGTGATGAGAGTCAGGCCGAGAAAAAGCCCTATCCCCTGCGACGTAGTGCGCGCAAACTCAAGCAGCCTGTGGAGAGCGACATTGAGGAATTGGAGTTGCAATTAGAACCATCGCCCAGCAAACGCCGTCGTGGTCGTCCGCCCGGCCCGGCCAAGCGCCAGTCTATGACCTCCGATGGCCGCCATGCCTGCAAGGTGTGCGGCAAGACCTTCTCCTGGTTCCGCGATATGCAGCGCCATGCCCGCATCCATTTCGAGAAATCCAACGCTTACGTATGCGACACCTGCGGCAAGGGATTCTTGCGCAAGGACAAGTACACATTCCATCTGCGCTGCCACGAAAAGCGCGATGCCAAAAGCAAGGCTCTGGAGCTGGGTAACGAGTGGCGTTTCGCCGAACGGCTATACAGTTCCGGCAGGCTGAAGAGAATCGAGTGCAAGCTGTGTGGCTTGAAGTGCTTGCGAATTCAAGAGCTGAGAACCCACTTGGTCAGCCATCAGGACGTGGAGAGCCTGTTCCAGTTGAGGAAGAATAGCGATGTAATCAAGGAGCACTATGCCGAGCTTCTAAACAACTTGGAAGGGGCCAAGCAGCAAATTATCAAGGACATAGAGGCAGGGCAATTGGAGAAGTTCGCTTCCGTGGTAAATTTCCATGGCTACGAGTTGGGATTGTGTGACTCGGACGAGGAATCATCCGGCGGAGAGTCCAAATATGAATGCACAATGTGCAATCTCTCCTTTTCCAGGAAACATCAAATGGTGAGGCACACGCTGGAGGAGCACGCTCAATCCTCTACTTCAGAGCTTCCCTGGCAACGCTGCGGGTTTTGTAAAGTCGGATTCCTGTGCTCCAGACTCTACGAGTGCCATGTAAACACCCAGTGCCAGAGCAAACTAAAGCGATATCGCTGCCCCAAGTGTCCGGGGAAGTTTATGTGGCCGGAGAATCAGCACAGGCACGCTTGCTCCCATAGTCACGAGGAAACCACGTCTGCCCGCCACATCTCATGCTCCTTGTGCGATGAAACGCTGCCCACTTTGGCTCAGTTGCGCATACACCTGGTTACCCACCAGAATAACATCAATCCGGAGCAAAATTCCACCTTCTTTCGTTCGTTCTATCCCAACGGATTGGACTGCACTCCCGAGGAGCTGGGTGTCCGCCTAGCCGAGGACTTTGAGGTGCAGGACTTTGATCGCTACTACAATGCCTGCACCGGCAGTGGCCAAGAGCTGGATCTCTTTGATTCCGAGACGGAGCAGAGTGGCGACGACCGGGAGGAGGAAGATAAGCCCGCCTCCCACACCTGTTTGCTGTGTGGAAAGGTCACAAACAGACTAACGACCCTGCTGCAGCACCAGAACAGTGCCCATTCAAGGGCCACGACGACTGAGTTGCCTTGTTCCTGCCAGGATTGTGGGGCTAGCTTTATAAGTGAcgccctgctgctgcagcaccgCCGTCGGATCTGTGGCAAGAAACATTTCCGCCATCACTGCCAGAGTTGCAATTTGCGGTTCATCTGGGCAAGCAACTACGAACTGCATCTGAAGACCCACCATAGCCaaggggaggaggagcaactcCTGGAGGGTGAGCATCGGGACGCCAAGCTGCAGTGCAATGAGTGCGAAAAGGTCTTTGTCTGGCACAAGGATCTCACGCGTCACAAGCGGCTGCACCTGCCTCAGTCGGCGCAATTCGAGTGTCCGCACTGCGACCGAAAGTTCCACCGCAAGGATGGCCTTAAGTCCCACCTGCGTGTGCACTCGGAAGAGCAGCCTCTCATAACCGAGAGAAGTCAGGTTCTTGCCCTGCTCTCCCGTCCTCATGGCTCCAAGCAGATCCAGTGCATGATATGCCTCTCCCGCCACTCCAAGATCTCTGATTTGCGAGCACACCTGGCCGCCCATCAGTATGGATTAAGCTTCTCCATGGAGACCGATATTTCCAATATCTCAAAGGCGCTGCATCCGGAAGTGGGTACAATCTTGGACAGAGATGAACTGGCAGAGAGGATAATGGCTGATGTGGAAAGCGGATTCGAGTTGGAACGATTTATTTCCATTACCAATGAGGCTGGTTTGGAGCTCAACTTGGACAGCAGCGAGACGGACACGGGATCCGagcaagaggaggagcagcattCTAAAATGAGATACTCCTGCCAGCTCTGTCCCACGGTGGTGAACAGAAAGCATAAGCTTTATGCCCACCAAGGGGAGACTCATCAGTGGGAGGAGGCACCATTTATTTGCTCCCACTGCCAGGCTAGGTTTGTCAGCGAATCCCTGCTGGAACATCACTCCAGGACCTTTTGCGGTAACGCCCTGAAGCGCTTCCAGTGTCGCAAATGTCCGCTCCGCTTCCGCTGGCCAGAGAACCTGAAGCAACACCTACATCTGTCCCATCAGCAGGCTGAGATGCCACCGGCAGAGGACTCTCCGCAAGCGGAAACCGAATTTCAATGTGGCGAATGCCAGCGAACGTTCAAGATGCAGAAGGATCTCACGCGGCACACCATGATGCATGCCCGGGAGGCCACGGTCTACCGTTGCCGTTGGTGTGCTCGTCGCTTCTACCGCTGGGCCAATCTCCTGCAGCACATCGCGCGCCATGGCATCCGAGCTAGTGAGTTTCACTATGCCGAGGCTCTGCTGGACTCCTACGGACATCCAGGCGGGCAGAAAACCGTGGAGTGCCGGGTGTGCAATGTCAGCTTCGCCAGTATAGCCGCCCTGCGTCTGCATCTGGAAACCATGCCGGCAGGAAGCCATCACGAGCTCTCCTCGTTGAAGAACTACTCGATCACCAACCAAATGGGCTTCGAACTGGAGCTCCAGGATTCGGAAACTGATGAGGAGCAGTCGAAGCCGCCCGGAGTACCTGCCTACTATACGTGCGGCATGTGCCAGCTAAGGTGCGTGCGAAAGTTCGAGCTgcaacagcaccagcaggCCATGCACCGGCTGGAGAAAATTCCCGATGGCTGCGACCAGTGCATCTTCAAAAGCGTTTGCCCCGATCTCATTGCCCATCACAAGAGGACGCAGTGCGGCAATCGGGAGAAACAGTTCACGTGCTCTCGCTGCGGCTACAAGTTCATGTGGGAGTCGAACCTGCTGACGCACATGCAGCTGCAGCACGGCAAGACAGACAATCCGGAGCAGGAGGAAGGCAAGGAGCCTTCGCCGGAAGAGCCAAAGGCCGGGAGCCCGGTTTTCCAGTGTGCCCTCTGTCCCAGGAAGTACAACCGAAAGGATCGTCTCTCAGCGCACGTTAAAAAGTTCCATGGACCCGATGGCCGTGGCCCCGATGTGGTCAAGGTTCGCCCTGCCAGAGCCGCCTCCCCCAAGGAACCAAAGCGCTTCCTGTGCGCCTTCTGCGGCAAGGCGGTCAGTTCCTCCTCCAACCTGATCATCCATATGCGTCGCCATACCGGCGAAAAGCCTTTCAAATGCGAGTTCTGCTCCATGGCCTTTCCACGATCGTCGGACCTTATGTGCCACCGACGAACGCATACCGGAGAGCGGCCGCACGTGTGTACCGTCTGCCAAAAGGGATTCGCCCGCTCCTacaagctgcagcagcacatGCGCATCCACAGCGGCGAGCGGCCGTACAAGTGCACCTATTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGTCGGCACACAGGCGAGCGGCCATATCAGTGCGGCATCTGCGGGGAGCGTTTCATCCAGGGAACAGCGCTGAAGAATCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGACTTCTGGGGAGCCTGCAAGGCGCACGGTTTTGGAACAGTTTACTGTATGA
Protein Sequence
MLPPNICRTCAVQNTDLRPLSTCLAKDASKSFYDVLQELTQIDPLVESSGDSLPQHLCTECLARLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEEQHIKTEVDIDEATPKFVVDSPGISPVEFKWQPESDSDEEPAEAAVSDESQAEKKPYPLRRSARKLKQPVESDIEELELQLEPSPSKRRRGRPPGPAKRQSMTSDGRHACKVCGKTFSWFRDMQRHARIHFEKSNAYVCDTCGKGFLRKDKYTFHLRCHEKRDAKSKALELGNEWRFAERLYSSGRLKRIECKLCGLKCLRIQELRTHLVSHQDVESLFQLRKNSDVIKEHYAELLNNLEGAKQQIIKDIEAGQLEKFASVVNFHGYELGLCDSDEESSGGESKYECTMCNLSFSRKHQMVRHTLEEHAQSSTSELPWQRCGFCKVGFLCSRLYECHVNTQCQSKLKRYRCPKCPGKFMWPENQHRHACSHSHEETTSARHISCSLCDETLPTLAQLRIHLVTHQNNINPEQNSTFFRSFYPNGLDCTPEELGVRLAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDREEEDKPASHTCLLCGKVTNRLTTLLQHQNSAHSRATTTELPCSCQDCGASFISDALLLQHRRRICGKKHFRHHCQSCNLRFIWASNYELHLKTHHSQGEEEQLLEGEHRDAKLQCNECEKVFVWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRVHSEEQPLITERSQVLALLSRPHGSKQIQCMICLSRHSKISDLRAHLAAHQYGLSFSMETDISNISKALHPEVGTILDRDELAERIMADVESGFELERFISITNEAGLELNLDSSETDTGSEQEEEQHSKMRYSCQLCPTVVNRKHKLYAHQGETHQWEEAPFICSHCQARFVSESLLEHHSRTFCGNALKRFQCRKCPLRFRWPENLKQHLHLSHQQAEMPPAEDSPQAETEFQCGECQRTFKMQKDLTRHTMMHAREATVYRCRWCARRFYRWANLLQHIARHGIRASEFHYAEALLDSYGHPGGQKTVECRVCNVSFASIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELELQDSETDEEQSKPPGVPAYYTCGMCQLRCVRKFELQQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNREKQFTCSRCGYKFMWESNLLTHMQLQHGKTDNPEQEEGKEPSPEEPKAGSPVFQCALCPRKYNRKDRLSAHVKKFHGPDGRGPDVVKVRPARAASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCSMAFPRSSDLMCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHYEEGQTSGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00491633;
90% Identity
iTF_00489499;
80% Identity
-