Basic Information

Insect: Drosophila bocki
Gene Symbol: ZNF296
Assembly: GCA_008042715.1
Location: VNJY01006398.1:8729-13111[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0016 0.12 12.8 1.5 1 23 208 230 208 230 0.96

2 25 1.5 1.1e+02 3.4 3.7 1 21 237 257 237 259 0.84

3 25 0.018 1.3 9.5 0.6 2 23 291 312 290 312 0.95

4 25 0.00012 0.0088 16.3 2.1 1 23 385 408 385 408 0.94

5 25 3.3 2.4e+02 2.4 2.4 1 23 449 471 449 471 0.91

6 25 0.0054 0.39 11.1 0.0 2 23 483 504 482 504 0.96

7 25 0.00093 0.067 13.5 1.2 1 23 577 600 577 600 0.96

8 25 0.0066 0.47 10.9 0.4 2 22 611 631 610 631 0.93

9 25 0.65 47 4.6 5.5 1 23 640 662 640 663 0.94

10 25 0.43 31 5.2 1.0 5 23 682 700 681 700 0.95

11 25 1.5e-05 0.0011 19.2 4.3 1 23 707 729 707 729 0.98

12 25 0.023 1.7 9.2 0.6 1 23 860 883 860 883 0.90

13 25 0.002 0.14 12.5 1.4 1 22 890 911 890 911 0.95

14 25 0.012 0.88 10.0 2.8 1 23 920 943 920 943 0.95

15 25 7.6e-06 0.00055 20.1 2.0 1 23 961 983 961 983 0.98

16 25 8.1e-05 0.0059 16.9 0.4 1 23 990 1012 990 1012 0.98

17 25 0.077 5.5 7.5 0.0 2 21 1039 1058 1038 1059 0.92

18 25 0.0032 0.23 11.9 2.2 1 23 1105 1128 1105 1128 0.96

19 25 0.0043 0.31 11.5 0.9 1 23 1165 1188 1165 1188 0.96

20 25 0.00096 0.069 13.5 1.3 1 23 1214 1237 1214 1237 0.97

21 25 4.8e-06 0.00034 20.8 0.2 2 23 1264 1285 1263 1285 0.95

22 25 0.0016 0.12 12.8 3.3 1 23 1291 1313 1291 1313 0.99

23 25 1.9e-06 0.00014 22.0 2.0 1 23 1319 1341 1319 1341 0.97

24 25 1.7e-07 1.2e-05 25.3 2.4 1 23 1347 1369 1347 1369 0.99

25 25 0.00062 0.045 14.1 0.1 1 21 1375 1395 1375 1399 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0016	0.12	12.8	1.5	1	23	208	230	208	230	0.96
2	25	1.5	1.1e+02	3.4	3.7	1	21	237	257	237	259	0.84
3	25	0.018	1.3	9.5	0.6	2	23	291	312	290	312	0.95
4	25	0.00012	0.0088	16.3	2.1	1	23	385	408	385	408	0.94
5	25	3.3	2.4e+02	2.4	2.4	1	23	449	471	449	471	0.91
6	25	0.0054	0.39	11.1	0.0	2	23	483	504	482	504	0.96
7	25	0.00093	0.067	13.5	1.2	1	23	577	600	577	600	0.96
8	25	0.0066	0.47	10.9	0.4	2	22	611	631	610	631	0.93
9	25	0.65	47	4.6	5.5	1	23	640	662	640	663	0.94
10	25	0.43	31	5.2	1.0	5	23	682	700	681	700	0.95
11	25	1.5e-05	0.0011	19.2	4.3	1	23	707	729	707	729	0.98
12	25	0.023	1.7	9.2	0.6	1	23	860	883	860	883	0.90
13	25	0.002	0.14	12.5	1.4	1	22	890	911	890	911	0.95
14	25	0.012	0.88	10.0	2.8	1	23	920	943	920	943	0.95
15	25	7.6e-06	0.00055	20.1	2.0	1	23	961	983	961	983	0.98
16	25	8.1e-05	0.0059	16.9	0.4	1	23	990	1012	990	1012	0.98
17	25	0.077	5.5	7.5	0.0	2	21	1039	1058	1038	1059	0.92
18	25	0.0032	0.23	11.9	2.2	1	23	1105	1128	1105	1128	0.96
19	25	0.0043	0.31	11.5	0.9	1	23	1165	1188	1165	1188	0.96
20	25	0.00096	0.069	13.5	1.3	1	23	1214	1237	1214	1237	0.97
21	25	4.8e-06	0.00034	20.8	0.2	2	23	1264	1285	1263	1285	0.95
22	25	0.0016	0.12	12.8	3.3	1	23	1291	1313	1291	1313	0.99
23	25	1.9e-06	0.00014	22.0	2.0	1	23	1319	1341	1319	1341	0.97
24	25	1.7e-07	1.2e-05	25.3	2.4	1	23	1347	1369	1347	1369	0.99
25	25	0.00062	0.045	14.1	0.1	1	21	1375	1395	1375	1399	0.91

Sequence Information

Coding Sequence: ATGCTTCCCCCAAACATTTGCCGCACTTGTGCGGTCCAGAACACGGATTTGCGGCCACTGTCCACCTGTCTGGCCAAAGACGCCTCAAAAAGTTTCTATGATGTGCTCCAGGAGCTAACACAAATCGATCCCCTGGTTGAGAGCTCGGGTGACAGTCTGCCGCAACATCTCTGCACCGAGTGCCTGGCGAGATTGGAAAGTGCCTATGCCTTTGTGGAACAGGCCAGGAAAGTCAATGGCGAGCTGTTGGTTCGCCTGCGGGAATGCCTCGATGAAATGCCCATTGACATTccgcaggaggagcagcataTCAAAACCGAAGTAGATATCGATGAGGCGACTTCCAAGTTTGTTGTGGATTCCCCAGGAATATCACCTGTGGAGTTCAAATGGCAGCCGGAAAGTGACAGCGATGAGGAACCTGCTGAAGCAGCAGTCAGTGATGAGAATCAGGACGAGAAGAAGCCCTATCCCCTGCGACGTAGTGCGCGCAAACTCAAGCAGCCTGTGGAGAGCGATATTGAGGAATTGGAGTTACCATTAGAACCATCGCCCAGCAAACGACGTCGTGGCCGTCCGCCCGGCCCGGCCAAGCGCCAGTCTATGACCTCCGATGGCCGCCATGCCTGCAAGGTGTGCGGCAAGACCTTCTCCTGGTTCCGCGATATGCAGCGCCATGCCCGCATCCATTTCGAGAAATCCAACGCTTACGTATGCGACACCTGCGGCAAGGGATTCTTGCGCAAGGACAAGTACACATTCCACCTGCGCTGCCACGAAAAGCGCGATGCCAAGAGCAAGGCTCTGGAGCAGGGTAACGAGTGGCGCTTCGCCGAACGGCTATACAGTTCCGGCAGGCTGAAGAGAATCGAGTGCAAGCTGTGTGGCTTGAAGTGCCCGCGAATTCAAGAGCTGAGAACTCACTTGGTCAGCCATCAGGACGTGGAGAGCCTGTCCCAGTTGAGGGAGAATAGCGATGTAATCAAGGAGCACTATGCCGAGCTTCTAAACAACTTGGAAGGCGCCAAGCAGCAAATTATCAAGGACATAGAGGCAGGGCACTTGGAGAAGTTTGCTTCCGTGGTGAATTTCCATGGCTACGAGTTGGGATTGTGTGACTCGGACGAGGAATCACCCAACGGAGAGTCCAAATATGAATGCACAATGTGCAATCTCTCCTTTTCCAGGAAACATCAAATGGTGAGGCACACCCTGGAGGAGCATGCTCAATCCTCTCCTCCAGAGCTTCCCTGGCAACGCTGCGGCTTTTGTAAAGTTGGATTCCTGTGCTCCAGACTCTACGAGTGCCATGTAAACACCCAATGTCAAAGCAAACTAAAGCGATATCGCTGCCCCAAGTGTCCGGGGAAGTTTATGTGGCCGGAGAATCAGCACAGGCACGCTTGCTCCCATAGTCACGAGGAAACCACGTCTGCCCGCCACATCTCATGCTCCTTATGCGATGAAACGCTGCCCACTTTGGCCCAATTGCGCATACACCTGGTTACCCACCAGAATAATATCAATTCGGAGCAAAATTCCACCTTCTTTCGTTCGTTCTATCCCAACGGATTGGACTGCACTCCGGAGGAGTTGGGTGTCCGCCTAGCCGAGGACTTTGAGGTGCAGGACTTTGATCGCTACTACAATGCCAGCACGGGCAGTGGCCAAGAGCTGGATCTCTTTGATTCCGAgacggagcaggaggaggacgagaAGCCCACCTCCCACACCTGTTTGCTGTGTGGAAAGGTCACAAACAGACTAACGACCCTGCTGCAGCACCAGAACAGCGCCCATTCAAGGGCCACGACGACTGAGCTGCCTTGTTCCTGCCAGGATTGTGGGGCTAGCTTCATAAGTGAcgctctgctgctgcagcaccgCCGCCGAATCTGTGGCAAGAAACATTTCCGCCATCACTGCCAGAGTTGCAATCTGCGGTTCATCTGGCCAAGCAACTACGAACTGCATCTAAAGACCCACCATTGCCaaggggaggaggagcaactcCTGGAGGGTGAGCATCGGGACGCCAGGCTGCAGTGCGAAAAGGTCTTTGTCTGGCACAAGGATCTAACGCGTCACAAGCGCCTGCACCTGCCTCAGTCGGCGCAGTTCGAGTGTCCGCATTGCGAGCGAAAGTTCCACCGCAAGGATGGCCTAAAGTCCCACCTGCGTGTGCACTCGGAAGAGCTGCCTCTCATAACCGAGAGTAGTCAGGTTCTTGCCCTGCTCTCCCGTCCTCATGGCTCCAAGCAGATCCAGTGCATGATATGTCTCTCCCGTCACTCCAAGATCTCTGATTTGCGAGCACACCTGGCCGCCCATCAGTACGGATTGAACTTCTCCGAGGAGACCGATATTTCTAGTATCTCCAAGGCGCTGCATCCGGAAGTGGGTACAATCTTGGACAGAGATGAACTGGCGGAGAGGATAATGGCTGATGTGGAAAGCGGATTCGAATTGGAACGATTTATTTCCATTACCAATGAGGCTGGCTTGGAGCTCAACTTGGACAGCAGCGAGACGGACACGGGATCCGAgcaagaggaggagcagctttCCAGCGTGAAATATGCCTGCCAGCTCTGTCCCACGGTGGTGAACAGAAAGCATAAGCTTTATGCCCACCAAGGAGAGACTCATCAGTGGGAGGAGGCACCGTTTATTTGCTCCCACTGCCAGGCTAGGTTTGTCAGCGAATCCCTGCTAGAACATCACTTCAGGACCTTTTGCGGCAACGCCCAGAAGCGCTTCCAGTGCCGCAAATGTCCGCTCCGCTTCCGCTGGCAAGAGAACCTGAAGCAACACCTACATCTGTCCCATCAGCAGGCTGAGATGCCGCCGGCAGAGGACTCTCCGCAAGCGGAAACCGAATTTCAATGCGGCGAATGCCAGCGAACGTTCAAGATGCAGAAGGATCTCACGCGGCACACCATGATGCACGCCCGGGAGGCCACGGTCTACCGTTGCCGTTGGTGTGCTCGTCGTTTCTACCGCTGGGCCAATCTCCTGCAGCACATCGCACGCCACGGCATCCGAGCTAGTGAGTTGCACTATGCCGAGGCTCTGCTGGACTCCTATGGACATCCAGGCGGGCAGAAAACCGTGGAGTGCCGGGTGTGCAATGTCAGCTTTGCCAGTATAGCCGCCCTGCGTCTGCATCTGGAAACCATGCCGGCGGGAAGCCATCACGAGCTCTCCTCGTTGAAGAACTATTCGATCACCAACCAAATGGGCTTTGAACTGGAGCTCCAGGATTCGGAAACTGATGAGGAGCAGTCCAAGCCGATCGGAGTACCTGCCTACTACACGTGTGGCATGTGCCAGCTGAGGTGCGTGCGGAAGTTCGAGCtgcaacagcaccagcaggcCATGCACCGGCTGGAGAAGATTCCCGATGGCTGCGATCAGTGCATCTTCAAAAGCGTATGCCCCGATCTCATTGCCCATCACAAGAGGACGCAGTGCGGCAATCGGGAGAAACAGTTTACGTGCTCCCGCTGCGGCTACAAGTTCATGTGGGAGTCGAACCTGCTGACGCACATGCAGCTGCAGCACGGCAAGACGGACAATCCGGAGCAGGAGGAAGGCAAGGAGCCTTTGCCGGAAGAGCCGAAGGCCGGGAGCCCGGTTTTCCAGTGTGCCCTCTGCCCGAGGAAGTACAACCGAAAGGATCGTCTCTCAGCGCACGTTAAAAAGTTCCACGGACCCGATGGTCGTGGCCCCGATGTGGTCAAGGTTCGCCCTGCCAGAGCCGCCTCCCCCAAGGAACCGAAGCGCTTCCTGTGCGCCTTCTGCGGCAAGGCGGTCAGTTCCTCCTCCAACCTGATCATCCATATGCGTCGCCATACCGGCGAGAAGCCTTTCAAATGCGAGTTCTGCTCCATGGCTTTTCCACGATCCTCGGACCTTATGTGCCACCGACGAACGCATACCGGAGAGCGGCCGCACGTGTGTACTGTCTGCCAGAAGGGATTTGCCCGCTCCtacaagctgcagcagcacatGCGCATCCACAGCGGCGAGCGGCCGTACAAGTGCACCTATTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGTCGGCACACGGGCGAGCGGCCCTACCAGTGCGGCATCTGCGGGGAGCGTTTCATCCAGGGAACAGCGCTGAAGAATCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGGCTTCTGGGGAGCCGGCAAGGCGCACGGTTTTGGAACAGTTTACTGTATGA
Protein Sequence: MLPPNICRTCAVQNTDLRPLSTCLAKDASKSFYDVLQELTQIDPLVESSGDSLPQHLCTECLARLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEEQHIKTEVDIDEATSKFVVDSPGISPVEFKWQPESDSDEEPAEAAVSDENQDEKKPYPLRRSARKLKQPVESDIEELELPLEPSPSKRRRGRPPGPAKRQSMTSDGRHACKVCGKTFSWFRDMQRHARIHFEKSNAYVCDTCGKGFLRKDKYTFHLRCHEKRDAKSKALEQGNEWRFAERLYSSGRLKRIECKLCGLKCPRIQELRTHLVSHQDVESLSQLRENSDVIKEHYAELLNNLEGAKQQIIKDIEAGHLEKFASVVNFHGYELGLCDSDEESPNGESKYECTMCNLSFSRKHQMVRHTLEEHAQSSPPELPWQRCGFCKVGFLCSRLYECHVNTQCQSKLKRYRCPKCPGKFMWPENQHRHACSHSHEETTSARHISCSLCDETLPTLAQLRIHLVTHQNNINSEQNSTFFRSFYPNGLDCTPEELGVRLAEDFEVQDFDRYYNASTGSGQELDLFDSETEQEEDEKPTSHTCLLCGKVTNRLTTLLQHQNSAHSRATTTELPCSCQDCGASFISDALLLQHRRRICGKKHFRHHCQSCNLRFIWPSNYELHLKTHHCQGEEEQLLEGEHRDARLQCEKVFVWHKDLTRHKRLHLPQSAQFECPHCERKFHRKDGLKSHLRVHSEELPLITESSQVLALLSRPHGSKQIQCMICLSRHSKISDLRAHLAAHQYGLNFSEETDISSISKALHPEVGTILDRDELAERIMADVESGFELERFISITNEAGLELNLDSSETDTGSEQEEEQLSSVKYACQLCPTVVNRKHKLYAHQGETHQWEEAPFICSHCQARFVSESLLEHHFRTFCGNAQKRFQCRKCPLRFRWQENLKQHLHLSHQQAEMPPAEDSPQAETEFQCGECQRTFKMQKDLTRHTMMHAREATVYRCRWCARRFYRWANLLQHIARHGIRASELHYAEALLDSYGHPGGQKTVECRVCNVSFASIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELELQDSETDEEQSKPIGVPAYYTCGMCQLRCVRKFELQQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNREKQFTCSRCGYKFMWESNLLTHMQLQHGKTDNPEQEEGKEPLPEEPKAGSPVFQCALCPRKYNRKDRLSAHVKKFHGPDGRGPDVVKVRPARAASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCSMAFPRSSDLMCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHYEEGQASGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00527450; iTF_00533218;
80% Identity: -