Basic Information

Insect: Drosophila lacicola
Gene Symbol: -
Assembly: GCA_035045355.1
Location: JAWNPB010000049.1:5638720-5670882[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.027 1.8 9.3 1.9 1 23 1247 1269 1247 1270 0.95

2 8 1 69 4.3 0.8 1 23 1275 1298 1275 1298 0.96

3 8 0.00022 0.015 15.8 0.8 1 23 1496 1519 1496 1519 0.96

4 8 0.0051 0.34 11.6 0.5 2 23 1528 1549 1527 1549 0.97

5 8 0.05 3.4 8.4 0.3 1 23 1556 1579 1556 1579 0.96

6 8 2e-05 0.0013 19.1 1.4 1 23 1585 1607 1585 1607 0.97

7 8 4.6e-06 0.00032 21.1 0.3 1 23 1612 1634 1612 1634 0.99

8 8 0.16 11 6.8 5.3 1 23 1640 1662 1640 1662 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.027	1.8	9.3	1.9	1	23	1247	1269	1247	1270	0.95
2	8	1	69	4.3	0.8	1	23	1275	1298	1275	1298	0.96
3	8	0.00022	0.015	15.8	0.8	1	23	1496	1519	1496	1519	0.96
4	8	0.0051	0.34	11.6	0.5	2	23	1528	1549	1527	1549	0.97
5	8	0.05	3.4	8.4	0.3	1	23	1556	1579	1556	1579	0.96
6	8	2e-05	0.0013	19.1	1.4	1	23	1585	1607	1585	1607	0.97
7	8	4.6e-06	0.00032	21.1	0.3	1	23	1612	1634	1612	1634	0.99
8	8	0.16	11	6.8	5.3	1	23	1640	1662	1640	1662	0.98

Sequence Information

Coding Sequence: atgagtgCCAACAAGCGACGACGTAGCAACAGCGAGAGCAGCCGCCAAATGGCCACAGCTGACTGCATGAATGCAGCCAAGGATGTACGCGGCGGCGGAGGAATTCAACATTCAACAATTGACGCGAGCGTCGGAGACGGCGTTGCCGAGCTGCTTCAAATGCCGCGCGtgtgtcgttgttgttgcaaagGCGACATGGAATTGCTCGGCCTTTTCGAGGCCAGCGTTGAGACAGCCAAACAGACAACACAACCTCAACGCCGACGCAAAACGACTACAATTGAAgaagcagcatcaacaacaaccacacaacaaaaacaacaacagcgcaaaTGTGATAATCCCGTTGAATATGCGCTCAGCGGTGCGCACAGCAGTATGGACACTGTGTTAGAGGAGATGATCATTTGGATGCTCAATATCTCACGCGATGATGGCCTGCCCCAGGAGATCTGTCGGCAGTGCAAGGCACAGTTCATAATGGTTGCCAAGTTCCGGCGGCGCTGCTTGCGTGTACAGCAGCGGCTAGAGGAGTATGCCAAGGAGATAGCCCAGCGCAAGAGATGTCTGGCCGCCAAGCAAGAGGAGCAACCACAGCAAAATGAGCCATCTGAAGAGTATTATCTGCATCTGCCCGAGTCACAAATTGAGCGCAAGCGTCGCCTGGTGCTTAGTAGCACCAAAACTGAAGCCGAACGCGTGCCGACGCCGCCCAAGCTGCGACGCCTGCAGCTCAGATTGCGCAACATGCGCATTGCCTCCTTGCCAGCTAACCAGATTGAGACTGAACAACCGACGCGAAGTGCGTCACAGCAGGGCGAATTAAAGGAGCGGACGCCACTGAGAATGCTATGCAAAAAAATGCACATGCCCTGGAAAACGAAGGCGGCACGCAAACAGCTCTCAGAAACGTGGTCCAGCTGTTCGACGGTCTCCCACTGCCGGGCAGCATCCATAACGTCAGAGGAGCTGACAAAGGCACAGTTGGCGACACCGTCGCGGGCGAAGAGTTCCGACCCGGAGACCGAAACAAGCGCAGGTCAAACGTCACCCGAGCAGCTCAGCGATTTGTCCGTGAATCCATGTCACGGCTTCGAAAGCGACTGCTGCCACAGTTGGTCGCCCCCCTCCTCCATTTCATCAGTAGCTATTCCCGCCACCCAGAACGCAACGACGCCTAAGCCGATTGCCCAGCTTCAGTTTCCACCAAAGCGCGAGACGCCCAAAAAACAGCTCGTGGTGCTGCGACGAGGACGACGTGGGCGTAGCTCTGTGCCGCTGAAGCGAGCGAAGCGCTttgcaaagaaaaagaagaagcaggcAATTGCAGAGAATCAAGAATTTGTTCAGCAGTCGACCAGTCAATCAAAAGAGCAACAGTGTGATGAGATACTCGCAGCCGGGGCAGAGAAGAAGCTGGCCAGCAGCTCCTCGGAAGAGACGCCGTGCTACAGTCAGGCTGTACAATCAGAAACCACCTCCGAGGATCTGGCGCACATGACAACAGATGAGGAGCGAGAAAAACCAAGTGATACAGCCGCAGATGCGACCAGAGCCGCTGCGAGCGGCAAGGAGAAGTCCACAGTAGCAACAAGTAAGTCCATGGAACAGCTGGAGCACGCGGCGCCAGAGCAGTTGCAGTCGCCCGACGCAACTGAACACCCTGcagaaaatgcaaacaatcAAACTCAGGTCAAAAGGCCAACAGAACCAATGCAAAGCATATCAAAGAAAGTAAACGAGATGGAGGAACAGATGGCCGTAGATGTAACCAGCcctttatacacacacaatggAACTGCAGAAACAGCTGATTCCACAGTTCAATCTGAAGAGCTCACTTCATCCACCATGGAGCACAGCCCCACAATCCAGGGCAGCTCCGAATGCGAAATAGAGCTGGGCATTGCAAACGATGAGCAGCAGCCCGCAGAGCAGCCGCCCCAAGAAGAGCAGGCCAATGCAGAGCCCGTGCAGCAGGCGGAGGAGCCAGCGTCGGAGCTTATAGTTAGCATACCGTTAGATGTGCTCGGCGACGAGCTGCAGCGAAAACTATGCAGCAGCGATCCAATCGCACAGGCTGAGGAAGAGGAAGCTCAGGATGCCGAGCCCAAGGAGACCGCGGAGGCGGACGATGTGAATAACAATGAGAATGGTGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATGCTGCTGTGGCACTCACAtccaaacaaattgaagcaGAACCAAATAGAGGGAAGGCAATTGTGCCACTCGATGACGACATGGAGTCGCTGGAACGATTAGCTGATATGCAGCCGCATGCACCGGTTGCGGAAGTGCAGCCGCTCCGTACTGTGAATGCCAGCTCCATGGATTTCTTAGCCGAATTCGAGAAGCACTGTGAGAAGACGCTCAAGCTGCAGGCCAAGGAACCGCCACTGGAAACGGAACTAGAACTGGTGGAGgccaaacagcagctgcaggtggAAATGAACGATGTGGAGAGCACCCTGCATGGCATACTGAATGAGATGCAGGACCAGCATCTCTATACGCCCGTCTGTACGCCGATTGATGAATTTCTAACGCCTGCCGATTATGTGCCGCTCAACGAGACGGAAGCGGCAGAGGCCACGCCAACAGCACCAGAGCTATACGCGTCGCCAGCTGAGACACCTCAGGGGCAGGTgccgccacagcagcagcagcagcagcaacaggtgaAGGAGGGGAATCTGTTTGATAGCAGCAACTTTAGCAATGAGCTGATCGGCTTCCAAAATGATATGCCCTGCTTTGAGAACATTGAGGCAACGCCTGAGTCGATGGCAGTGCAGCAGAgcctgcagctggagctgacGCAGTTGCTCAATGAGCTTCAGCCGGCACAGCAGCAgttacaacagcagcaacagcagctgcagccgctgccgctgcaacaacagcaacagttgcagctacAGCAGGAAGCTGTCAGCTATGAGGCTGTGTATCAGGCACCGCTTACCGCCCAAGCTCCAGTGAACGGCAATAAGTTGCAGCTCATCCAAATGCAGCCGCAGGAGACGCTGTGGCAGGCACAGGCAACAGCCGCACAGCAGACGACAACCACACAACTGCAATGGTCGACTGTGGGCGGGCTGGAGGCCATCAAGACGACACCTGTTGCCGGCCTGGATAGTCTGGATGGCAGCGGCACAACCACCTACTACATCAATGCCAGCGATCTCTACCagacgcagctgcagcagcaaccagcTCACCTGACGGCCGATAGCTATGCACTGCTCGATAGCAATGAGAACTACGTGctggaggagcagcaacaacagcagcagcagcagcagcagcccattATGATACTCATACAGCAGTcagagctgcagcagccagaaCTGCAGCAGCCGGTGGCATCCGCCAGCAATCCGCAACAGGCGCCGCTGCATATAACATACGGCACCAGCCTGGCTAATGAGCTGCACGCCTATccccaacagcagcggcaccagcagcaacaacagcagcagcaggaacgtacacaacaaaagccacaacaacaaaaacctcACTCACAgtcacaacaacaagtacaaaATACAGTATTAGGCTCggctgctgccgttgcgcCGCCCACCCGCGGCCGACCGCCGATGCTCAAGTGCCGCTTCTGTCAGAATGGACCGCGTTTCTCCAGCAGCCTGGAGTATAGTCGTCACATCATTGAGCTGCATCCGGCGGTGGCGCCCTTCAATTGTCCCCACTGCCCGCTGGCCTTTGCCGGTCGCAGCAAGCGCAGCCAGCACATCCTCAACCACCACATGGTGCAGCAGTTCCACTGTGGCCAATGCTCGCTGATGTTGCCCTCGCAGCGTGCTCTGGATTTGCATCTGCAACGCTTTCACATGCCGCTGCCAACGGAATCGGCCCCGTCCGAAAATCCAGCGGCTGGCGCCGTGCGCCTAGACGAGGTTCAACTGCAAATAGCCAACAAGAGAGAGCTCCcaaaactgcagcaacagcatagGTCGCCGCATATGCCTGCTTTGGATCTTGAAACAAGCCCGCCACAGCCACGCAGGACGCGCATACTATGCTGCCCGGACTGCGAGGACTGCTCAAGTGGACACAGTCATGGCAGCGGTCAGTCGACATACGAGGAGCTGACCAATCTGCAGCCACCGCCGACGGTGCTGACGCCGCCGTCGACAATTGCATCATTGCCGTCGCCGCAGCCAACGCCGCACATAACGTTGCCCTCGCCGGAGCAATCGGAGCCGGACTCGACGACGGCAACCTTGCGGCAGTTTCGCAAGCGCTGCGTGGCCAACAGCAcgacaggaacaacaacaccagtcgcagcagcaccaacggcagctgcagctgcagcagcaacaatgctaACAACAGCCGCATCGCCGTCGCCCTCCTCGTCGCCGTCCTCGTCGACCATGGAGACGAGCGTAACGCTGCAGCTGGGCaaactgagcagcagccaccAGTGCGTGATCTGCGAGAAGCGTTTTACCAATATCATAGCGCTTCGCAAGCACCAGCAGCTGGCCCATGATTCGCAGACATCCATGCCCTGGGTGTGCGGCATTTGTAAGCGTGGCTATCGGAAGCGCACCGACATGGATAATCATATGAAATCACATGAGCCCAAGGGTCGTCCGTACGAGTGCAATGAGTGTTGGGTACGTTTTCCGGAATTCAAACAGCTGGCAATGCACAAGTTCACCGTCCATGAGCTGATCAAGCCGCATACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGAAAGCGGCTTCGAGTGCGACGAATGCGGCGAGGCATTCGCCTATATCAAAGATTTGCGCAAACATCGGCGCACCCACAACAGTgaattattttacaaatgcGACTACTGTCCACGCACGTTTCTACATTTTTCGAGCCATCGTGCACATATAAATACCCACCTGCCGCTGGGCGTATTCCTCAACGATAAGATGCCCAGCAGCGTGAGCAGCAAATTTGAGAATCCTTCAACGCCAGCAATTACCGAGGAATCGCTGCCATTGACGCCGCTTAGCAattgcaatggcaacggcGGCAGCATCGAGGATTGCCCCGGCTCTGTGGAGTTGGTGGAGAGCAGTGTAGCGCCATCGTTGGATATGATTGTGGATACGCCATAA
Protein Sequence: MSANKRRRSNSESSRQMATADCMNAAKDVRGGGGIQHSTIDASVGDGVAELLQMPRVCRCCCKGDMELLGLFEASVETAKQTTQPQRRRKTTTIEEAASTTTTQQKQQQRKCDNPVEYALSGAHSSMDTVLEEMIIWMLNISRDDGLPQEICRQCKAQFIMVAKFRRRCLRVQQRLEEYAKEIAQRKRCLAAKQEEQPQQNEPSEEYYLHLPESQIERKRRLVLSSTKTEAERVPTPPKLRRLQLRLRNMRIASLPANQIETEQPTRSASQQGELKERTPLRMLCKKMHMPWKTKAARKQLSETWSSCSTVSHCRAASITSEELTKAQLATPSRAKSSDPETETSAGQTSPEQLSDLSVNPCHGFESDCCHSWSPPSSISSVAIPATQNATTPKPIAQLQFPPKRETPKKQLVVLRRGRRGRSSVPLKRAKRFAKKKKKQAIAENQEFVQQSTSQSKEQQCDEILAAGAEKKLASSSSEETPCYSQAVQSETTSEDLAHMTTDEEREKPSDTAADATRAAASGKEKSTVATSKSMEQLEHAAPEQLQSPDATEHPAENANNQTQVKRPTEPMQSISKKVNEMEEQMAVDVTSPLYTHNGTAETADSTVQSEELTSSTMEHSPTIQGSSECEIELGIANDEQQPAEQPPQEEQANAEPVQQAEEPASELIVSIPLDVLGDELQRKLCSSDPIAQAEEEEAQDAEPKETAEADDVNNNENGENFCQSATADSFNAAVALTSKQIEAEPNRGKAIVPLDDDMESLERLADMQPHAPVAEVQPLRTVNASSMDFLAEFEKHCEKTLKLQAKEPPLETELELVEAKQQLQVEMNDVESTLHGILNEMQDQHLYTPVCTPIDEFLTPADYVPLNETEAAEATPTAPELYASPAETPQGQVPPQQQQQQQQVKEGNLFDSSNFSNELIGFQNDMPCFENIEATPESMAVQQSLQLELTQLLNELQPAQQQLQQQQQQLQPLPLQQQQQLQLQQEAVSYEAVYQAPLTAQAPVNGNKLQLIQMQPQETLWQAQATAAQQTTTTQLQWSTVGGLEAIKTTPVAGLDSLDGSGTTTYYINASDLYQTQLQQQPAHLTADSYALLDSNENYVLEEQQQQQQQQQQPIMILIQQSELQQPELQQPVASASNPQQAPLHITYGTSLANELHAYPQQQRHQQQQQQQQERTQQKPQQQKPHSQSQQQVQNTVLGSAAAVAPPTRGRPPMLKCRFCQNGPRFSSSLEYSRHIIELHPAVAPFNCPHCPLAFAGRSKRSQHILNHHMVQQFHCGQCSLMLPSQRALDLHLQRFHMPLPTESAPSENPAAGAVRLDEVQLQIANKRELPKLQQQHRSPHMPALDLETSPPQPRRTRILCCPDCEDCSSGHSHGSGQSTYEELTNLQPPPTVLTPPSTIASLPSPQPTPHITLPSPEQSEPDSTTATLRQFRKRCVANSTTGTTTPVAAAPTAAAAAAATMLTTAASPSPSSSPSSSTMETSVTLQLGKLSSSHQCVICEKRFTNIIALRKHQQLAHDSQTSMPWVCGICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGESGFECDECGEAFAYIKDLRKHRRTHNSELFYKCDYCPRTFLHFSSHRAHINTHLPLGVFLNDKMPSSVSSKFENPSTPAITEESLPLTPLSNCNGNGGSIEDCPGSVELVESSVAPSLDMIVDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506453;
90% Identity: iTF_00491129;
80% Identity: -