Basic Information

Insect: Drosophila ezoana
Gene Symbol: -
Assembly: GCA_035045725.1
Location: JAWNOU010000197.1:1693482-1725997[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.026 1.9 9.3 1.9 1 23 1244 1266 1244 1267 0.95

2 8 1 71 4.3 0.8 1 23 1272 1295 1272 1295 0.96

3 8 0.00022 0.016 15.8 0.8 1 23 1491 1514 1491 1514 0.96

4 8 0.005 0.35 11.6 0.5 2 23 1523 1544 1522 1544 0.97

5 8 0.049 3.5 8.4 0.3 1 23 1551 1574 1551 1574 0.96

6 8 1.9e-05 0.0014 19.1 1.4 1 23 1580 1602 1580 1602 0.97

7 8 4.6e-06 0.00033 21.1 0.3 1 23 1607 1629 1607 1629 0.99

8 8 0.16 12 6.8 5.3 1 23 1635 1657 1635 1657 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.026	1.9	9.3	1.9	1	23	1244	1266	1244	1267	0.95
2	8	1	71	4.3	0.8	1	23	1272	1295	1272	1295	0.96
3	8	0.00022	0.016	15.8	0.8	1	23	1491	1514	1491	1514	0.96
4	8	0.005	0.35	11.6	0.5	2	23	1523	1544	1522	1544	0.97
5	8	0.049	3.5	8.4	0.3	1	23	1551	1574	1551	1574	0.96
6	8	1.9e-05	0.0014	19.1	1.4	1	23	1580	1602	1580	1602	0.97
7	8	4.6e-06	0.00033	21.1	0.3	1	23	1607	1629	1607	1629	0.99
8	8	0.16	12	6.8	5.3	1	23	1635	1657	1635	1657	0.98

Sequence Information

Coding Sequence: ATGGCCACAGCTGACTGCATGAGTGCAGCCAAGGATGTGGGCGGCGGCAGAGGAATTCAACAATCAGCAATTGACGCCAGCatcggagacggagacggcgTTGCCGAGCTGCTTCAAATGCCGCGGGtgtgtcgttgttgttgcaaaggCGACATGGAATTGCTTGGCCTTTTCGAGGCCAGCGTTGAGACAGCCAAACAGACAACACAAAGTCAACGCCGACGCAAAACAACTACAAttgaagaagcagcaacaacaacaacaacgaccgcacaacaagaacaacaacagcgcaaaTGTGATAATCCCGTTGAATATGCGCTCAGCGGTGCGCACAGCAGTATGGAAACTGTGTTAGAGGAGATGATCATTTGGATGCTCAATATCTCACGCGATGATGGCCTGCCCCAGGAGATTTGCCGGCAGTGCAAGGCGCAGTTCATAATGGTTGCCAAGTTCCGGCGGCGCTGCTTGCGTGTACAGCAGCGGCTAGAGGAGTATGCCAAAGAGATAGCCGAGCGCAAGAGATGTCTGACAGCCAAGCAAGAGGAGCAATCACAGCATAATGAAGAGTATTATCTGCATCTGCCAGAGTCACAAATGGAGCGCAAGCGACGCCTGGTGCTTAGTAAGGAGGTGGCACAGTTGGAATCGCAGCCGAAACAAGCCAAGACTAAAGCCGAACGCGTGCCGACGCCGCCCAAGCTGCGACGCCTGCAGCTTAGATTGCGCAACATGCGCATTGCCTCCTTGCCAGCCAACCAAATTGAGACTGAACAACCGATGCGGAGTGCGTCGCAGCAGGACGAATTAAAGGAACGGTCGCCCCTGAGAATGCTATGCAAAAAAATGCACATGCCCTGGAAAACGAAAGCGGCACGCAAACAGCTCTCAGAAACGTGGTCCAGCTGTTCCACGGCCTTCCACTGCCGGGCAGCGTCCATAACGCCAGAGGAGCTGACAAAGGCACAGTTGACGTCACCGCCACGGGTGAAAAGTTCCGACACGGAGAACGAAACAAGCGCAGGTCAAACGTCACCCGAGCAGCTCAGCGATTTGTCCGTGAATCCATGTCACGGCTTCGCAAGCGACTGCCACGATTGGTCGCCGCCCTCCTCCATTTCATCAGTAGCCACTCCCGCCACCCAAGACGCAGCGACGCCTAAGCCAACTGCCCAGCTGCAGTTTCCACCAAAGAGCGGGACGCCCAAAAAACAGCTCGTGGTGCTGCGCCGAGGACGACGTGGGCGTAGCTCTGTGCCGCTAAAGCGAGCGAAGCGCATtgcgaagaagaagaagatgcaAGCAACTGCAGAGAATCATTTGTCCAAGCAGAAGATGGAGCAATCAACCAGTCAACCAAAAGAGCAACAGTGTGAAGAGACACTCGCAGCCGGGGCAGAGGAGAAGCTGGCCAGCAGCTCCTCGGATGAGACGCCATGCTACAGTCAGGATGTACAATCAGAAACCACCTTCGAGGATCTGGCGCCCATGACAACAGATGAGGAGCGAGAAAAACCAAGTGAAACAGCGGCAGATGAGACCACAACCGCTGAGAGCGACAAGGAGAAGCCCACAGTAGCAACAAGTGAGTCCATGGAACAGCTGGAGCACGCCGCGCCAGATCAGTTGCAGTCGCCCGACGCAACTGAATGCCCTGCAGAAAATGCAACCAATCAAACTCAGGACAAAAGGCCAACAGAACAAATGCAAAGCATATCAAAGAAAGTAAACGAGACAGAGGAACAGATGGCCGTAGATGTAACCAACCCTTTATGCACACACAATGGAACTGCAGAAACAGCTGATTCCACTGTTCAATCTGAAGAGCTCACTTCATCCACCATGGAGCACAGCCAGCCAATCCAGGGCAGTCATTGCCTGTCGCCGGAAGTGCCAGCTTCCGAGTGCGAAATAGAGCTGGGCATTGCAAATGACGAGCAGCAGCTCGAAAAGCAGCCATCCGTTGAAGAGCCCGTGCAGGAGGCGGAGGAGCCAGCGTCGGAGCTTATAGTAAGCATACCGTTAGATGTGCTCGGCGACGATCTGCAGCGGAAACTATGCAGCAGCGATCCAATCGCgcaggaggaggaagaggaagatCAAAATGCCGAGCAGAAGGAGCCCGCAGAGGCGGACGATGTGAATAACAATGAGAATGGTGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATGCTGCTGTGGCACTCACAACCAAACAAATTGAAGCAGAACCAAATGGAGGGAAGGTAGTCGTTCCACTCGACGACGACATGGAGTCCCTGGAACGATTAGCTGATATGCAGCCGCCTGCACCGGTAGCGGAAGTGCAGCCGCTCCGTGCTGTGAATGCCAGCTCCATGGATTTTTTGGCCGAATTCGAGAAGCACTGCGAGAAGACGCTCAAGCTGCAGGCGAAGAAGGCGCCACTGGAAACGGAACTAGAACTGGTGGAGGCCAAACAGCAGCTGGAGGTGGAAATGAACGATGTGGAGAGCACCCTGCATGGCATTCTGAATGAGATGCAGGACCAGCATCTCTATACGCCTGTCTGTACGCCGATTGATGAATTTCTAACGCCTGCCGATTATGTGCCGCTCAACGAGACGGAAACGCCAGCGGCCACGCCAACAGCGCCACAGCTCTACGCGTCGCCAGCTCAGACACCTGAGGGGCAGGTGTCGcctcagccgcagcagcaacaggtgaAGGAGGGGAATCTGTTTGATAGCAGCAACTTTAGCAATGAGCTGATCGGCTTCCAAAATGATATGCCCTGCTTTGAAAACATTGAGGCAACGCCTGAGTCGATGGCAGCGCAGCAAAgcctgcagctggagctgacGCAGCTGCTCAATGAGCTGCAGCCAGCACAGCAGCAAtcagcacagcagcaacagccgctgccgctgcaacaacagcaacagttgcagctacAGCAGGAAGCTGTCAGCTATGAGACACTGTACCAGGCACCGCTTACCGCCCCAGCTCCAGTGAACGGCAATAAGTTGCAGCTCATCCAAATGCAGCCGCAGGAGACGCTGTGGCAGGCACAGGCGACAACCGCACAGCAGACGACAACTACACAGCTGCAATGGTCGACTGTGGGCGGCCTGGAGGCCATCAAGACAACACCTGTTGCCGGCCTGGATAGTCTGGACGGCAGCGGCACCACCACCTACTACATCAACGCCAGCGATCTCTACCagacgcagctgcagcagcaaccagcTCATCTGACGGGCGATAGCTATGCAATACTCGATAGCAATGAGAACTACgtgctggagcagcagcagcaacagcagcagcaacccaTTATGATACTCATACAGCAGCcagagctgcagcagccggtGGCATCCGCCAGCAATCCGCAACAGGCGCCGCTGCAAATAACATACGGCACCAGCCCGGGCAATGAGCTGCACGCCTTTCCCAcacagcagttgcagcagccgcagcaactgcagcagcagcagcatcagcaacaacagcaccagGAACGTACACAACaaaagccacaacaacaaaaacctcACTCACAgtcacaacaacaagtacaaaATACAGTATTAGGCTTGCCTGCTGCCGTACCGCCGCCCACCCGCGGCCGTCCGCCCTTGCTCAAGTGCCGCTTCTGCCAGAATGGTCCGCGTTTCTCCAGCAGCCTGGAGTATAGTCGTCACATCATTGAGCTGCATCCGGCTGTGGCGCCCTTCAATTGTCCCCACTGCCCGCTGGCCTTTGCCGGTCGCAGCAAGCGCAGCCAGCACATCCTCAACCATCACATGGTGCAGCAGTTCCACTGTGGCCAATGCTCACTGATGTTGCCCTCACAGCGTGCTCTggatttgcatttgcagcgcTTTCACATGCCGCTGCCAACGGAATCGGCCGCGTCCGGAGAaccagctgctggcgctgtgCGCCTAGACGAGGTTCAACTGCAAATAGCCAACAGGCGAGAGCTTCcaaaactgcagcagctgaagacGTCGCCGCATATGCCAGCTTTGGATCTTGAAACAAACCCGCCACAGCCACGCAGGACGCGCATACTCTGCTGCCCGGACTGCGAGGACTGCTCAAGTGGACATAGTCATGGCAGCGGCCAGTCGACGTACGAGGAGCTGACCAATTTGCAGCCACCGCCGACGGTGCTGACGCCGCCGTCGACAATTGCATCGGTGCCGTCGCCGCAGCCAACGCCGCACATAACGTTGCCCTCGCCAGAGCAATCGGAGCCGGACTCGACGACGGCAACTTTGCGGCAGTTTCGCAAGCGCTGCGTGACCAATTGCACGACAGGAGCAACCACACCAGTCGCAGCAccaactgcagcagttgctgcggCAACAATGCTAACCACAGCCGCATCGCCGTCGCCCTCCTCGTCGCCGTCCTCGTCGACCATGGAGACGAGCGTAACGCTGCAGCTGGGCAAACTGAGCAGCAGCCATCAGTGCGTGATCTGCGAGAAGCGTTTTACCAATATCATAGCGCTTCGCAAGCACCAGCAGCTGGCCCATGATTCGCAGACATCCATGCCGTGGGTGTGCGGGATTTGTAAGCGTGGCTATCGGAAACGCACCGACATGGATAATCATATGAAATCCCATGAGCCCAAGGGTCGTCCGTACGAGTGCAATGAGTGTTGGGTACGTTTTCCGGAATTCAAACAGCTGGCAATGCACAAGTTCACCGTCCATGAGCTGATCAAGCCGCATACCTGCGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGAAAGCGGCTTCGAGTGCGACGAATGCGGCGAGGCATTCGCCTATATCAAAGATTTGCGCAAACATCGGCGCACCCACAACAGCGAACTATTTTACAAATGCGATTACTGTCCACGCACGTTTCTACATTTTTCGAGCCATCGTGCACACATAAATACCCACCTGCCGTTGGGCGTGTTCCTCAACGATAAGATGCCCAGCAGCGTGAGCAGCAAAATTGAGAATCCTTCGACGCCAGCAACTACCGAGGAATCGCTGCCATTGACGCCGCTTAGCAGTTGCAATGGCAACGGCGGCAGCATCGAGGATTGCCCCGGCTCTGTGGAGTTCGTGGAGAGCAGTGTAGCGCCATCGTTGGATATGATTGTGAATACGCCATAA
Protein Sequence: MATADCMSAAKDVGGGRGIQQSAIDASIGDGDGVAELLQMPRVCRCCCKGDMELLGLFEASVETAKQTTQSQRRRKTTTIEEAATTTTTTAQQEQQQRKCDNPVEYALSGAHSSMETVLEEMIIWMLNISRDDGLPQEICRQCKAQFIMVAKFRRRCLRVQQRLEEYAKEIAERKRCLTAKQEEQSQHNEEYYLHLPESQMERKRRLVLSKEVAQLESQPKQAKTKAERVPTPPKLRRLQLRLRNMRIASLPANQIETEQPMRSASQQDELKERSPLRMLCKKMHMPWKTKAARKQLSETWSSCSTAFHCRAASITPEELTKAQLTSPPRVKSSDTENETSAGQTSPEQLSDLSVNPCHGFASDCHDWSPPSSISSVATPATQDAATPKPTAQLQFPPKSGTPKKQLVVLRRGRRGRSSVPLKRAKRIAKKKKMQATAENHLSKQKMEQSTSQPKEQQCEETLAAGAEEKLASSSSDETPCYSQDVQSETTFEDLAPMTTDEEREKPSETAADETTTAESDKEKPTVATSESMEQLEHAAPDQLQSPDATECPAENATNQTQDKRPTEQMQSISKKVNETEEQMAVDVTNPLCTHNGTAETADSTVQSEELTSSTMEHSQPIQGSHCLSPEVPASECEIELGIANDEQQLEKQPSVEEPVQEAEEPASELIVSIPLDVLGDDLQRKLCSSDPIAQEEEEEDQNAEQKEPAEADDVNNNENGENFCQSATADSFNAAVALTTKQIEAEPNGGKVVVPLDDDMESLERLADMQPPAPVAEVQPLRAVNASSMDFLAEFEKHCEKTLKLQAKKAPLETELELVEAKQQLEVEMNDVESTLHGILNEMQDQHLYTPVCTPIDEFLTPADYVPLNETETPAATPTAPQLYASPAQTPEGQVSPQPQQQQVKEGNLFDSSNFSNELIGFQNDMPCFENIEATPESMAAQQSLQLELTQLLNELQPAQQQSAQQQQPLPLQQQQQLQLQQEAVSYETLYQAPLTAPAPVNGNKLQLIQMQPQETLWQAQATTAQQTTTTQLQWSTVGGLEAIKTTPVAGLDSLDGSGTTTYYINASDLYQTQLQQQPAHLTGDSYAILDSNENYVLEQQQQQQQQPIMILIQQPELQQPVASASNPQQAPLQITYGTSPGNELHAFPTQQLQQPQQLQQQQHQQQQHQERTQQKPQQQKPHSQSQQQVQNTVLGLPAAVPPPTRGRPPLLKCRFCQNGPRFSSSLEYSRHIIELHPAVAPFNCPHCPLAFAGRSKRSQHILNHHMVQQFHCGQCSLMLPSQRALDLHLQRFHMPLPTESAASGEPAAGAVRLDEVQLQIANRRELPKLQQLKTSPHMPALDLETNPPQPRRTRILCCPDCEDCSSGHSHGSGQSTYEELTNLQPPPTVLTPPSTIASVPSPQPTPHITLPSPEQSEPDSTTATLRQFRKRCVTNCTTGATTPVAAPTAAVAAATMLTTAASPSPSSSPSSSTMETSVTLQLGKLSSSHQCVICEKRFTNIIALRKHQQLAHDSQTSMPWVCGICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIKFHGESGFECDECGEAFAYIKDLRKHRRTHNSELFYKCDYCPRTFLHFSSHRAHINTHLPLGVFLNDKMPSSVSSKIENPSTPATTEESLPLTPLSSCNGNGGSIEDCPGSVEFVESSVAPSLDMIVNTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00617267; iTF_00531285; iTF_00491129; iTF_00534907; iTF_00526909;
90% Identity: -
80% Identity: -