Basic Information

Insect: Drosophila lacicola
Gene Symbol: ken1
Assembly: GCA_035045355.1
Location: JAWNPB010000133.1:11631815-11634172[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.1 7.1 7.4 5.4 3 23 244 264 242 264 0.96

2 12 0.00069 0.047 14.3 0.7 1 23 270 295 270 295 0.94

3 12 0.016 1.1 10.0 0.2 1 23 302 327 302 327 0.92

4 12 0.00063 0.043 14.4 5.1 1 23 337 359 337 359 0.97

5 12 0.00023 0.015 15.8 1.9 2 23 367 388 366 388 0.96

6 12 0.0078 0.53 11.0 0.5 1 23 394 416 394 416 0.97

7 12 0.28 19 6.0 3.9 1 23 422 445 422 445 0.96

8 12 0.0014 0.097 13.3 1.9 1 23 451 473 451 473 0.97

9 12 0.0097 0.66 10.7 0.8 2 23 480 501 479 501 0.97

10 12 0.0002 0.014 16.0 0.8 1 23 590 613 590 613 0.95

11 12 0.15 9.9 7.0 1.9 1 21 619 638 619 641 0.73

12 12 0.0024 0.16 12.6 3.1 1 23 647 670 647 670 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.1	7.1	7.4	5.4	3	23	244	264	242	264	0.96
2	12	0.00069	0.047	14.3	0.7	1	23	270	295	270	295	0.94
3	12	0.016	1.1	10.0	0.2	1	23	302	327	302	327	0.92
4	12	0.00063	0.043	14.4	5.1	1	23	337	359	337	359	0.97
5	12	0.00023	0.015	15.8	1.9	2	23	367	388	366	388	0.96
6	12	0.0078	0.53	11.0	0.5	1	23	394	416	394	416	0.97
7	12	0.28	19	6.0	3.9	1	23	422	445	422	445	0.96
8	12	0.0014	0.097	13.3	1.9	1	23	451	473	451	473	0.97
9	12	0.0097	0.66	10.7	0.8	2	23	480	501	479	501	0.97
10	12	0.0002	0.014	16.0	0.8	1	23	590	613	590	613	0.95
11	12	0.15	9.9	7.0	1.9	1	21	619	638	619	641	0.73
12	12	0.0024	0.16	12.6	3.1	1	23	647	670	647	670	0.97

Sequence Information

Coding Sequence: atggATGGGGGGAGTGAATACTCCATACACTCGATATGTCGCACTTGCTTGAACCACCTGCGAAACGATCCGGCCTACGACCTGTTTCTGGTCCCAGGTCTCGCCAAGAAACTTTGTGTGTGCACTTCACTCTCCGTGGAAAAACACGATGGGTTTCCCAAAAACCTTTGCTCCACTTGCCACACTCGACTCATCGACTTGCACGGATTTCAAAAGCAATGTGTAGACTCTGTGCAAAGGTTTCAAGAAATGGTCgccaacaattattttatacccGACATGGGTAATGTTGACAATGACGGCTTAATGAGTGCTGCGGCACACGATGGGGAAACAGAGGAGGATCGCATCAACTTTGACCCGCTCCTAAATACTAAAATAGAGGTAGTGGAGAATGAGGAGgatgtttttaaaatgttggaTGATGTCGACAAAGAAGTTGAGGAGGTTGAGAAGAATCCCTCCAGTGACAACGAAAAcgacaatgatgatgatgcgcgTTTAAAAGCGAATAGCAGCGCCTCAGAAGACGCCATGCCCTTGTCCCGCTTACGAAGTGCTACGAGAGCATCCAAAGCAAaggccaaaagaaaaattgtagTAGATGATGAAGATTCCTCTAGCTTTGAGTGGTGTATCGAAAATGATGATAAAAAGGACAAACCTAAAACGAAACCAAAACGTAAACGCATTCCAAAGGCCGATGTGCAACTTGACGATCTGATTGATTGTCACATTTGTCATGAAAAATTCGAGAGCACAAAACTTTACGACGACCACATGAAGCATCACAACGATCTATTGCCATTCCAATGCACTGTGGAGTCCTGCAAGAAGGGTTTCTCTACGTCTGGTGGCCTACGCCTGCATATGGACCACGCTCACTCAGAACTCTCTGAAGTGCACGCCTGCACTGTGGAAGGATGTGGCATGACATTTCCTCGACCTGTTTTACTGACGTTCCATTTGAAAAAAGTACACAAGATTATAACGTCTCGGGCACGGGATCATCCATGCACGGAATGCGACAAAGTTTTCCGCTGTTCAACGGCTCttaaaaaacatatgtataagcATACTGGCGAGGAGAAGCCTATATCCTGTAACATCTGCAACAAAAGGTTTCACATAAATAGTGAGCTCAAGGACCATCTCTTGCGCCATGCCGGGGTGAAAAATCATGTCTGTCCTTATTGTGGCGTGGGCAAAACAACTCGACAGGAGTGGAATAAACACATTTTGACGCACACCAAGGAAAAACAGTTTCATTGTCTTCAGTGCGATCATTCCTCCCACAACAAGCAGGCCTTGGCCAATCATGTCAAAGTGGTTCATATGAAGATTAAGAACTATGCCTGTCAGTACTGTGGGAAGACTTTTGGCAAGTCGTATGCCTGTAAGGTCCACGAGAGAATCCACACCGGCGAAAATTGCTCCCAGTGCAAAATCTGTGGCAAGGTCTTGCTTTTCGAGAGGAGCTTAACAAAGCATTTAAAGCTTCATGAAAAGCGCGAATTACGAGCATCAGCGACTACTGTCAAACCGCAGGTCGACGATGATTCGCAAAGCACTCTGAAATTGAACCAGGAGGTGAATGATCCAGTGGACACGAAACCCATATCAAAAGAACAAACTAAGCCGTTGAATCCTTATAGGCTTAAGCGTGTAGATATATCCGAACTTGCGGGTACTGCTGTCAACCCCATATCTTCAGTCTCTGTGGAATCCTCTTCACCGCTGGTCAACTTTACAAAGAAAGAAGGCCAGCATATTTGTCCAGGTTGTGGCCGGGGCTTCAACCACATTGGCAATATGAAGCTTCACTATAAGATAATACACTTAAAGGTGAAGGATTTCGCATGTCGCTTCTGTCCCAAACGTTTTTCAAAGGCACAAATTTTACGACATCATGAATGGACTCACACCGGCGAAAAACCGTTTGAATGCAAGATATGCGGCCTACACTTTAGGCAGGAAAAAGTAATGAAGACGCATGTAAAAAGGAAGCACGAGAATCCGGCGAAACCTCGCAAAGAACCTAAGCCCCAAAAAGCTAGTAAAGAAAAAAGACCGAAGATGAATCTTAACAAAAAACCGCCTAAGATTCTTGATGAGTACCAGGAACCCGCTGCAGAACGtgccgcagcaacagctgctctGCTCGCGCAACAGATTGAGGAGAATGAAGCGAAGCGAAAGGCGGAGGAGGAAACTCGAAAGATTCAAGAGGCCGCATGCGAACAACTGCAGATGCTGCAAAAGGAACAGCTTATCGAGAAGATATCCAGTGATAGCTTTCAAGTAAAATCGTCCGAGACGGGTATCAGCGTGGATGACCTCAAAAAAGATtcagtttaa
Protein Sequence: MDGGSEYSIHSICRTCLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEKHDGFPKNLCSTCHTRLIDLHGFQKQCVDSVQRFQEMVANNYFIPDMGNVDNDGLMSAAAHDGETEEDRINFDPLLNTKIEVVENEEDVFKMLDDVDKEVEEVEKNPSSDNENDNDDDARLKANSSASEDAMPLSRLRSATRASKAKAKRKIVVDDEDSSSFEWCIENDDKKDKPKTKPKRKRIPKADVQLDDLIDCHICHEKFESTKLYDDHMKHHNDLLPFQCTVESCKKGFSTSGGLRLHMDHAHSELSEVHACTVEGCGMTFPRPVLLTFHLKKVHKIITSRARDHPCTECDKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSELKDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFHCLQCDHSSHNKQALANHVKVVHMKIKNYACQYCGKTFGKSYACKVHERIHTGENCSQCKICGKVLLFERSLTKHLKLHEKRELRASATTVKPQVDDDSQSTLKLNQEVNDPVDTKPISKEQTKPLNPYRLKRVDISELAGTAVNPISSVSVESSSPLVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHLKVKDFACRFCPKRFSKAQILRHHEWTHTGEKPFECKICGLHFRQEKVMKTHVKRKHENPAKPRKEPKPQKASKEKRPKMNLNKKPPKILDEYQEPAAERAAATAALLAQQIEENEAKRKAEEETRKIQEAACEQLQMLQKEQLIEKISSDSFQVKSSETGISVDDLKKDSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532579;
90% Identity: iTF_00526831;
80% Identity: -