Dlac007984.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lacicola
Gene Symbol
RREB1
Assembly
GCA_035045355.1
Location
JAWNPB010000148.1:3410729-3418428[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0062 0.42 11.3 0.6 1 21 249 269 249 271 0.96
2 13 0.00036 0.024 15.2 0.2 1 23 281 303 281 303 0.98
3 13 8.6e-05 0.0058 17.1 7.3 1 23 309 331 309 331 0.98
4 13 0.24 17 6.3 1.7 2 20 545 563 545 565 0.93
5 13 0.0094 0.64 10.7 0.1 1 23 716 738 716 738 0.97
6 13 1.3e-05 0.00089 19.7 0.7 1 23 748 770 748 770 0.99
7 13 0.00088 0.06 13.9 2.0 1 23 776 799 776 799 0.97
8 13 0.0032 0.21 12.2 2.0 1 23 1069 1092 1069 1092 0.95
9 13 9.2e-05 0.0062 17.0 0.3 2 23 1456 1477 1455 1477 0.97
10 13 0.15 10 6.9 6.3 1 23 1483 1506 1483 1506 0.97
11 13 10 6.7e+02 1.2 3.4 1 23 1628 1651 1628 1651 0.78
12 13 0.0089 0.61 10.8 0.5 3 23 1717 1737 1715 1737 0.96
13 13 0.0014 0.096 13.3 4.8 1 23 1743 1765 1743 1765 0.99

Sequence Information

Coding Sequence
atGCTggccgcacagcagcagcagcagcagcagcagccacaacagcaacacacagcggcaacagcaacagcgacggGAGGCAGCACAGTAGCGCTTGAGGATGCGGGCTTGGAGCGGGCGCGCCGCGATTCGAGCACCTCGGAATCCTCGCTGGAGCATCTGGACTTGGGCCGCACGCCAAAgaagctgagcagcagcagcggcgcgcCGCagccgacgtcgacgccgcACGAGGCGACGTCGCGCAAGCGCAagctgcgccagctgcagcagccgcaacagttGCTCTCCGACGAGgacgagcaacagcagcaacagcagcagcagcagcagctgctggagcagtCCGCGCAGCGACTGCGGCACAAGCAGCGACGCAGCGGAAAtgcagccgcagtcgctgccgctgccagcgccAGCATCGTGGTCGACTATAGCGCCAGCGGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGCCTAAAtcgcagcagcgccagcagcatcAATGGCAACAACGGGGAGCTATCCGAGTCCGGCTTTGTGGATGGGAGTGCGCACAGCGGCTATTTGctcagcgccagcagcgccgCGCAGTCAGCGtcggcagcgcagcagcagcagcagcaacagcagcagcagcagcaattggcctcaaacagcagcagctccggcGGCAGCTCGCCCCAGGGCCTGTGCCACTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAATATGTTTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCATCAGCCTCCTCGCTGGACAGGCACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAATTGTCGCTATTGCCATTTGACATTCACCACGAACGGCAACATGCACCGGCACatgcgcacacacaagcagcaCCAgacgtcgcagcagcagcagcaacaacagacaccgcagcagcagcaacagacacagcagcaacagacacCGCAGCAacatgcacagcagcagcaacatggacagcagcagcagcagcagcgacgccagcaaCATGGCGGCGCGGCAGCGGGGCGCGCGGAGAGCTACGAGAGCGATGCCAGCTGCTCGACGGATgtgtccagcagcagcagcagcagcgacagcagcaacagcaacaacaacaacaacaacaacaacagcgagcaaacgaacaagaacaacagcaacggggagcagcagcagcaactgttgctggcgTGCAAGCAGCGACGGCTTAAGAcgaacatcaacaacaacaatatcctCAGCGACGAGGagcagccaaagcagccaAAGTCCGAGCCCGAGGCAGAGGAAGAGCCCGAGCCAGAGCCGGACTCGGATGATGCGGAGAGCGTGGATGTGGCGCAGATGATCACAAGCACGCCGGATGTGGCCACATTGCTGGCAACTAGCCCGCCGAGCCCGTCGCCGGGCCTGCAGAGCTGTCCGGCCTGCAATGCGGGCGAGTTTGAGACATTGCCGGCGCTGTGCGCGCATCTGGATGCAGTGCATCCGGATATACCCGCAAAGTGTCGCGACTGCGAGGTGATCTTTGCCAGCCATCGGCAGCTGCAGGCGCACAGTTGTCGcggccagctgcagttgccgccgctgctcgGCGCGAGCAGCTCGCCGCTCCacaagctggagctggagcacgaccaggagcaggagcacgAGGAGGAGCACGgccaggagcaggaggaggatgaggaggaggagcagctggcCAGCAGCGAGCGCGACGAGTTCTTTCAGCAGCTCTATCTCAAAGGCAAAGCCGGCGGTTTGCCGTCGCCCATTAAGCGTGAGCCGTCCGAGCAGCGGCTGGAGCAGCGCCAGGATCGTCAGGATCTGGCCGATATACAGAGCATTCTGCATAtgaccagctccagctgcaccTCGAGTTTCCTGCGCAATTTCGAGCAGTCCGTCAACACGCCCTGCTCCAGCCAATACAGTCTGGACGGGCGCGACGGCGAGGAGGAGGCCCAGGATGCGTTTACCAGCGAATTCCGCCGGATGAAGCTGCGCGGCGAATTCCCGTGCAAACTGTGCAGCGCTGTCTTTCCCAATTTGCGCGCCCTCAAGGGCCACAATCGCGTCCATTTGGCCGCCGTCGGCGCCGCCGGACCCTTTCGCTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCATAACGGAGATCGGCCGTACGAGTGCGCCGTCTGCAATTATGCCTTCACCACGAAGGCCAACTGTGAGCGGCATTTGCGCAATCGGCACGGCAAGACCAGCCGCGAGGAGGTCAAGCGCGCCATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAACAAACGTGCAACGGGCCAGGATACGGATCTGGCCGAGCTCAGCTATCGTTCGCTCagtccgccgccgccgccgccgccgccgccgtcgttgCCCCTTGCCGTTGCCTTGCCGCCGGCAGCGGAATCGCAGCTAAAGCACATGTTGCTAGCGGAACCGTGCACCAAGCCGCCGGCGACGCCGCTCAAGATCCAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCTGGCGCCGCCAGCCATGGATCTCAGCATGGACGTGCTGGATCTGAGCAAGAAGCCGACACAGCAGCGCGAACGCGAGCGCGAACAGGAGCacgatctgctgctgctccaacagcagcaacagcagcaacagttgcaggtgcagcagcagcagcaacagttgcagcagcagcagcagcagcagctgtttggcGCGGGAGACGCGACGACGCAGTatatgcagcagctgctgcgcaatcTCATGTTCCCGCAGACGCCGGGCTTCTCCATCTTTGGCTAtatggcgccgccgccgccggcgacgacgacgacgtcggcgACGGAGAAGTCAACGCAGCCGGGCACAAATCCCGGCCAGACGCCGGCAACAGTTGCCATGCCGATGTCGGTGCCAACCATGTCCAtgccggtgccggtgccaGCGGGCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAGCGTCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTTACGCTGCGCTCCAACATGGAGCGGCACgtcaagcagcagcatcccCAATACTATGCGCAGCGCCAGCGCAGCGGACACCATGTGATGCGCGGACGCGCCGCCAGCTCCaatgcggcggcagcggcggcggcagcagcggcagcggcagcggcagcagcagcggcagccatgTCGAAtctggcgcagcagcagcagcagcagcatgcgCATCCGCCCATTTCGGAGCAGGTGAAGTATGCGATATtggcgcagcagctgaaggCGCGCAAGGATACGGATCTGCTGCATCAGGCGCTGGCGCACGGCTCCAGCAGTGCGCTGCTCCActtcaactacaacaacaacaacagcaacaacaacagcaacagcaacaacaacagcaacaacaacaataagcagcagcagcagcagcagccggcggcACATGCCATCaatggagctgctgctgctgcggatgATGATGAGCCGCCCAAGCTGATCATCGACGAGGACGatgaggagcaggagcaggagcaggaggtggaggaggaggaggagtttGATGATACAGAGGAGGAGCcggacgaggaggaggagcagctcGAAATGGAGGAGGACGCGATTGAGCAGGAGCCGGAAAAGCTCGAACAGCCTACGgcggctgccacgcccacgacgctgccacgccccggcACGCCCATTGAGGCAGCCAAAAAGGTAGCGGAGAGCATACTGGAGCAGGTGATCAAGGCGCAGGCCAAGCCCGATCCGGAATCCGATGCCGTTGCCATGCCAacgcccacaacaacaacaacaacaacaactccgACGACAATGAAAACAATGATAGCCCAAGCGGAATCGGTGGCGAAATCGTTGAAAGATGTGGCCAGCTCGCCGTTCAAGGACGAATCTCAGGATCTGGTGCCGGTGTCGAAGCTGGTGGACAACGCGACCAGCAATCAGGTCTCGTTCAACAGCTATTTCCGGCCGAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGTTTGGTTGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAcgtgaccagcagcagctgcaacgaACCCAAAAAGAAATCCGCCTACAGCTTGGCGCCAAATCGTGTCAGTTGCCCGTACTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTGCGCCGGCACATTCTGACCCATACGGGCCAGAAGCCCTTCAAGTGCTCGCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGGCATCTGTTGCGCAAGCACGGCAATGTCGAGTCCGCGATGAGCGTCTATGTGCCCACCGAGGATGTCAGCGAGCCGATACCAGTGCCCAAATCCGTCGAGGAGATCGCCCTGGAGGAGCAGCGACGACGCAAGGCCGCCGAGGCGGAGCGCCAGCTGGAGCGGGAGCGCGAAAGAGAGCGCGAACGGGAGCGCGAACGGGAGCGCGAacgcgagcagcagcagcagcagcagctcatccaGCAGCTGACGGCGGCGGCACAGCTGCGCCAGCAACTGgccaacgccgccgccgccgcagccgcagctgcagtcgtagccggagccggagccggcaACAGTCCAACGGCTGGGGGCGAGGGGGGAAACGGCAGCGAGCTGCCGTACAAATGCCATCTGTGCGAGTTCTCGTTCGGGGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCATGGCCACGAGTTTgccctgctgctggccaaaggcGCCATCGAAACGGATCAGCtccacgagcagcagcagcaacaattgttgtcgtcgtcatcCAATCCAGCGGCAGCTGGCTCCGAGGATGAATCGCTGGCGACGTCGGGTCGCAATGGCAGCGGCAATGGCAAATATCCGGACTATAGCAATCGGAAGGTGATCTGTGCGTTTTGTGTGCGCCGCTTCTGGTCGACGGAGGATCTGCGCCGGCATATGCGCACACATTCCGGCGAACGGCCGTTCCAGTGCGAGATCTGTTTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGTCACAATGGCGAGCAGGGCGCATCCGATTGTTCCGACGACGAGCAGTTGGTCACGCCGCCCGGCACGCCCACGCCAACGCCCacgcccagcaacaacagcaacaacaacaacaacaacagcagcacttgccagaacaacaacaacaacaagcagagcCTGCGCCTGGACAAGACCGGGCCCGACTGGCGCCTGCAGAAGGATAAAATTGGcgatgccacgcccacagcgacTGCAGCCGCCTTTGGCATGGCCAGCGGCGATCTGATCGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCGGACGAGGCGGCCAAGCTGCTGGGCGTCGAAAAGTAA
Protein Sequence
MLAAQQQQQQQQPQQQHTAATATATGGSTVALEDAGLERARRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHEATSRKRKLRQLQQPQQLLSDEDEQQQQQQQQQQLLEQSAQRLRHKQRRSGNAAAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSINGNNGELSESGFVDGSAHSGYLLSASSAAQSASAAQQQQQQQQQQQQLASNSSSSGGSSPQGLCHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTSQQQQQQQTPQQQQQTQQQQTPQQHAQQQQHGQQQQQQRRQQHGGAAAGRAESYESDASCSTDVSSSSSSSDSSNSNNNNNNNNSEQTNKNNSNGEQQQQLLLACKQRRLKTNINNNNILSDEEQPKQPKSEPEAEEEPEPEPDSDDAESVDVAQMITSTPDVATLLATSPPSPSPGLQSCPACNAGEFETLPALCAHLDAVHPDIPAKCRDCEVIFASHRQLQAHSCRGQLQLPPLLGASSSPLHKLELEHDQEQEHEEEHGQEQEEDEEEEQLASSERDEFFQQLYLKGKAGGLPSPIKREPSEQRLEQRQDRQDLADIQSILHMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEENNKRATGQDTDLAELSYRSLSPPPPPPPPPSLPLAVALPPAAESQLKHMLLAEPCTKPPATPLKIQVKSLDQLVEKPLAPPAMDLSMDVLDLSKKPTQQREREREQEHDLLLLQQQQQQQQLQVQQQQQQLQQQQQQQLFGAGDATTQYMQQLLRNLMFPQTPGFSIFGYMAPPPPATTTTSATEKSTQPGTNPGQTPATVAMPMSVPTMSMPVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQYYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAAAMSNLAQQQQQQHAHPPISEQVKYAILAQQLKARKDTDLLHQALAHGSSSALLHFNYNNNNSNNNSNSNNNSNNNNKQQQQQQPAAHAINGAAAAADDDEPPKLIIDEDDEEQEQEQEVEEEEEFDDTEEEPDEEEEQLEMEEDAIEQEPEKLEQPTAAATPTTLPRPGTPIEAAKKVAESILEQVIKAQAKPDPESDAVAMPTPTTTTTTTTPTTMKTMIAQAESVAKSLKDVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIALEEQRRRKAAEAERQLEREREREREREREREREREQQQQQQLIQQLTAAAQLRQQLANAAAAAAAAAVVAGAGAGNSPTAGGEGGNGSELPYKCHLCEFSFGERLQCLEHIKQLHGHEFALLLAKGAIETDQLHEQQQQQLLSSSSNPAAAGSEDESLATSGRNGSGNGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGASDCSDDEQLVTPPGTPTPTPTPSNNSNNNNNNSSTCQNNNNNKQSLRLDKTGPDWRLQKDKIGDATPTATAAAFGMASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00563368;
90% Identity
-
80% Identity
-