Basic Information

Insect: Drosophila lacicola
Gene Symbol: hang
Assembly: GCA_035045355.1
Location: JAWNPB010000148.1:29749751-29763152[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.4 27 5.6 1.0 3 23 491 512 490 512 0.93

2 18 1.1 78 4.1 3.2 3 22 619 638 617 638 0.89

3 18 0.00086 0.058 14.0 3.3 1 22 719 740 719 742 0.90

4 18 0.099 6.7 7.5 0.1 2 21 754 773 753 774 0.93

5 18 0.00099 0.067 13.8 0.2 2 23 905 927 904 927 0.95

6 18 0.0029 0.19 12.3 0.1 1 23 935 958 935 958 0.96

7 18 0.00022 0.015 15.9 0.2 2 23 1044 1065 1043 1065 0.97

8 18 0.00041 0.028 15.0 2.9 2 23 1189 1211 1188 1211 0.97

9 18 0.032 2.2 9.0 0.2 2 23 1220 1242 1219 1242 0.95

10 18 0.0017 0.12 13.0 0.1 1 23 1255 1278 1255 1278 0.97

11 18 0.00018 0.012 16.1 1.1 1 23 1314 1336 1314 1336 0.99

12 18 0.0028 0.19 12.4 0.9 1 23 1344 1367 1344 1367 0.96

13 18 0.097 6.6 7.5 0.4 2 19 1375 1392 1375 1393 0.94

14 18 0.0001 0.007 16.9 0.4 3 23 1501 1521 1500 1521 0.98

15 18 0.0072 0.49 11.1 0.1 1 23 1556 1578 1556 1578 0.97

16 18 0.00085 0.057 14.0 0.6 2 23 1667 1689 1666 1689 0.93

17 18 0.0092 0.62 10.7 0.3 3 23 1745 1765 1745 1765 0.98

18 18 0.0001 0.0068 16.9 2.0 1 23 2248 2270 2248 2270 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.4	27	5.6	1.0	3	23	491	512	490	512	0.93
2	18	1.1	78	4.1	3.2	3	22	619	638	617	638	0.89
3	18	0.00086	0.058	14.0	3.3	1	22	719	740	719	742	0.90
4	18	0.099	6.7	7.5	0.1	2	21	754	773	753	774	0.93
5	18	0.00099	0.067	13.8	0.2	2	23	905	927	904	927	0.95
6	18	0.0029	0.19	12.3	0.1	1	23	935	958	935	958	0.96
7	18	0.00022	0.015	15.9	0.2	2	23	1044	1065	1043	1065	0.97
8	18	0.00041	0.028	15.0	2.9	2	23	1189	1211	1188	1211	0.97
9	18	0.032	2.2	9.0	0.2	2	23	1220	1242	1219	1242	0.95
10	18	0.0017	0.12	13.0	0.1	1	23	1255	1278	1255	1278	0.97
11	18	0.00018	0.012	16.1	1.1	1	23	1314	1336	1314	1336	0.99
12	18	0.0028	0.19	12.4	0.9	1	23	1344	1367	1344	1367	0.96
13	18	0.097	6.6	7.5	0.4	2	19	1375	1392	1375	1393	0.94
14	18	0.0001	0.007	16.9	0.4	3	23	1501	1521	1500	1521	0.98
15	18	0.0072	0.49	11.1	0.1	1	23	1556	1578	1556	1578	0.97
16	18	0.00085	0.057	14.0	0.6	2	23	1667	1689	1666	1689	0.93
17	18	0.0092	0.62	10.7	0.3	3	23	1745	1765	1745	1765	0.98
18	18	0.0001	0.0068	16.9	2.0	1	23	2248	2270	2248	2270	0.99

Sequence Information

Coding Sequence: ATGGTTGCCTGCTGCTCGAGTTCGAAActcagcacagcacagcacagctcGGCGCGACGCAACGACTCTCTGGACTGCGCCCCCGGCAACGACATCATCATCTacgtcggcgtcgtcgtcgtcgtcggcacGTTGCTGCTGCGTGTGCTTGGTGCTTGGTGCTGGCACTGGGCTGCTCTTTGGTTTCGCTTTGGCTCGATTTCATGCTATTTGAACTCTTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCCAAGCAGCGGCAATGGCTGGACACCGATAAAAGCAAGCAGCAGACACTTTTAGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCTCCAttgaacaacagcagcacgaaACGAACATCGATTCAGCGACAGTTGCAGCTGAAAAGGCGTCCGCCAACATATTGGATGGCATACCCTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagctacaacagcaacaacagctacaacaacagcagcaacaacaacaacaacaacagcagcagcagcagcagcaacagaatgCTGCAAGAACAACGAGCGCGGCGGCGGAGTCACAGCAAACACTGCAGACCCTTTTATTGCAGGTGCCCTCAGCAATATTGTCAACGGCGTCaactcagcagcagcagcaacagcaacaacagcgcaaatatcaacagcagcagcagcaacgtgGCAGGCAGCAACATTACCaccagcaacatcagcagcagcaacaacatcagcagcagcaacaacatcatcagcagcgACTGAGTCGAATACGTCAACCACGACGCCAGCAACAGGCTGCGGCAACGTCTGCTCAGCGTTTGGCTAAGTTCAAGCCTAAATTGTGTTTACCATTGGATATATCAGTGCCACCGCTTCCAccgttgttgccgccgccgttgccgccaATGTTGTCAACtattgttgctggtgctgatTTGgcgccgttgccattgccgctgccgcttgATTTCAGCCAGAGTCAGTGTCAGAATCCGAACGCGAATCAGAGTCAGAAACATGGCAGCGTgttgccgccaccgccaccgccgccgccgccgctgccgctggctcCAGTTGCAGCAATGACCAGCAacgcctctgcctctgcctctgccactgccgcagccgcagccgcagtcacGACACCATTGCTCATGCCGCCGCTGCCTGCCATGCCCATCAAGGATGAGCCCATTGACGACACGGATGATGACTTCCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAGCATGGCGTGACGGCGGTTGTGGCGGCGGCATCGCTGCCCGCCAGCGCGGTTGCAAATGTGGCCGCCGCTGGCGACTCCAAGGTGGCCAGCTGCCGTGCCTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGACGCCACGAGCGCAATCTCCATCCGAATCTGTTCCAATTGTCGACAGACTCGCCAAATAATACGCCCATCACAAAACCGACGCCGGCATTGGCAGCCGCGCTGGAGATACAGCGTGCAGCTGCCGCGGCAGCGGCCACCGCGGAGGCAACTAAGGCTGCCGCCGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTCATGAACACGTTCATCAAGTGCGAGAACGGCGGCTTCGACTACGACAATCCGGAACAGTATCAGCCGCTGCTCACACGCGACAAGGTTGACTTCATTCAAGAGAACAACGAGTTTCTGGAACAGTACCAGACGATGacctgccgctgctgcaacAAATACTTTAACACATACAAGAACTTTATGGCGCACGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATTTATGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGCGTTCTCAACGCTCTCCGCGTCAAGCAGCCAAACTTCTCGCATGCCACCGCATCCGGAGTGGCTGTCTCAACCGATATGAGTGCTGTTCAagAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAACTGTACGAGTGCAAGCTCTGCCCAAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGATTGGACTTTGCCGATCCCGTAGATCGTCGCCGTCACTACAACAACATGGACTGCATTGTGCGGCTACGCTGCATGACCTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGCGTCAGCAGCGACAATGCGTCCACCGCGAACAGCGGCATGGATCATTCGCCGGGCAAGCGCAGCCTGCTGGGCGCTCTTGGCATTGGTGTCAGTCAGTCATCCAATGATGAgtcgcgcagcagcagccacaacaacaacaacaacaacaatgcagcgGAAACGCCGCTCACCTCAACGCCGAAGCCAGCTGCGTCGGGAACTGCAGCTGCGGCGACCAGTGGCGGCGGCTCCACATCCACATCTGGCAATCGCGATGCACCCAAATCGCAGTATTTTTCCCGCATGCCGCAGGTGTGCCCCATTTGTGGCCAGCagtacaacaactacaacaacgtGCTGCGCCACATGGAGTCAAAGCATCCAAATAAACTGCCCGAAACGTACAAATGTGTACGCTGCGGCCTTGGCTATCCGCGAATCTCATATCTGCGCGAGCACATGATTAATGTGCATGGCGTGGACAAGAATCGGCATTCCGGAGGCTTTGAATATATTGTTAATGCCGATGCTGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACCGGACGCTATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgATGATGAGGACGAGGAAAGCGGCAGCGTTGCCAAAAAGATGCGCCTCgatgacagcagcaacaacagcagcatcaacatgAGCATCGCCAATCAGCAAAAGGAATGCCTCATCTGCAATGCGGTgttcagcaacaacattggCCTATCCAATCACATGCGCTCGCATTATACCGCCTCCACGACGACAAGTGCAGCGCTGGCGGCGGCCAATCGCATGACGCCAAAGTCACTGACAATTACCGCAACGCCGCCGCTGGAAACGGCTGCCGCATCGTCCGCTGCGTCCGCTGCGGtgtcagcggcggcggcagcgacagcagcaacagcagcagcaacgcccGCCACaagcacagctgcagctgccgccgcagctgcgagtgcaactacaacaacaagtacaacaacagcagctgccgccgccgccgccgccgcgtcAGGCAGTTTGCCGCCGGCGATGGCACATCAAACGCCACAGGAGCAGGCGGTATTCCGACGTAGCCTGGACCAGGCAGCCGATCGTCGCTTTCGGCGCATGCGCTGTCGCATCTGCCAGCGCAGATTTAGCTCAAAGAAATCGTACCGCTACCACATGCTGACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCATCTCTTCAAGGTGCACGGACGAGCCATTAAGGACGAGATGATTGTGAAGCAGTTCGAGTGCGATATCTGCTCCATTGTCTACAGCTctgagctggagctgcagcagcacaagcGCAGCGTGCACAAGTCCCAGCCGGGCGCCAGTGATGCGGCCAAGTCAAAAGCGTCGGCTGCCGATCTCGCCGAGAGCTCCACGGGCACGGCTGTGCCCGCCCTGCCGCTCTACTGGTACCAGTGCAAGTACTGTCCATCCAATTTCAATACCAACAAAAAGCTGGCCATACACATCAACTCGCACGACGAGTTCGACTCGAACGATTATTCGTGCAAGGACTGCGGCAATGTCTACAGTGGCCGCAAAAGCCTTTGGgTGCATCGCTATAAGAAGCATCCGCAGGTGCCGGATCCCGCTGAGTGCACGCTGTGCCGCAAGATGTTCTTTGACCGCCAAATGCTGGAGAATCACACGCCCACCTGCAATCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCAGGattcgcagcagcagcagcagcagcagcagcagcagcagcagcaacagcaactgcaactgcaacagcagcgcggCATATTCAAGCACAAAACGGGCGACGatgacgaggaggaggatgatgaTCAGCTGATGTTGCTGGACGACGGTGTCTgcgtcggcagcagcagcagcaacggcggcggcggcaatgctgcaacagcagctgcagcagcagcagctgcatcgaGCAATGCCAATAGCAGCACATTGAAGATACGCATACCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTCAGCAAGCATATACAGAAACACGAACAGGATCTGTATGTGGATAATCCATTGGCGGCCATGTTCGATGATGGACCAGCGGACGCTGGCCAATTTCAGGTGGAGCGCCAGAACGAGAACGGGGAATACGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAACGctgaacaacagcagcagcagcaacagcaacaacaacaacaacaacaacaattcgctGAGCTCCTCGTCGATGCTGCATCTGCGCGAACTGCATGCTGTGGGCCTGATGCCCAATCAGCAGCaccagaaacaacaacagcaacaacaacaacagcagcagcagcaacaacagcagcagcagcagaggaaaTCGCTGAAACGGAAACGTGAACTGAAATGCGAATATTGCGCATCCACATtcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATTTGCCGGAGCCGCCAGTGATTGAGGTGGATGAGCCTTTAAGCTGTCGCCGTTGCGGCGATCTGCAGTTCGATACCAAGGAGCTGTGGATCGAGCACAAATTGGCCGATGCCAAGGTGGTGCGTCCCTTCTGTCCATTCCAATGGGGCTGCGATCTGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTCATTGTGCctgtggtggtggtggtggccgCCACCAAGCCAGCCTCAACTGCAACCAGCAagaatgcaacaacaaaatctgcagcaacaacagcagcggcagcaactggaGGCACAAAGGGCATAATCAGAGCGGGAGCAGTAAGAGTgcttaaacataaacaatcggatgagctgcaggagcagctgcaggacATGAAAGTGGCGAAGCGGCAGCAAAGTGTTCATGTGGAtgaggaggcggcggcggggcaggagcagcagcagcagcagcagcagcaggatgaGGCGGATGATAGTGATATGGATGATGATAGCGGCGATAGTGGCGACGATGATGAGGATAGCACAAGcgccgatgatgatgacgacgacgatgatgatgatgacgacgacgaagaTGATGAGGACGATGAGGGCGATGtggacgatgacgacgatgacgaagaTATTGtggaacagcagctgctgcagcaacagcaacaacaacaacaacaacaacaacagcaacagtctctcaatagcaacaagaacaagaacaacaataacaacaacagcgtggTTGCAAATGAGGATGACGATGATCTCATTGAGGAGGTAATCGAGGATGATGGCATTGTCGAGGAGCTAGAagatgatgaggatgatgacgaggacgacgacgacgacgacgacgaggccGATggcgttgatgatgatgatgacgatggtAACACAACGGATGAGCATCAGGCGCTGCCTTCCAATGCcaccaagcagcagcagccgaggcGCCTCAACTTTGACTACACGCGCACAGACAGCTCCAAGCTGAACGGCAATGGGAAAccgacgccgacgacgacgccgacgccgcagCAGCATCGGCAAAAGCCAAAGGGTCAGCAGGCGGTGCTGGTCGTGCACAGCTCAGAGGATGAGGATGCGGATGAGGATGCTGAGGCTGATGTCGACGGGGATGAGGATGTGGATGACGATGTggaggaggatgaggagggcgtgggcgtgggtgaAGCAATGACCATTGATGATATTATTGAAGAAGATGATGGggaggatgatgatgacgatgtgGTTGGTGTCGATGGTGCTGTTGttgaggatgatgatgatgatgttgaggAAGATATGGACGAGGATGACgtggacgacgacgacgacgacgatgacgacgacgacgaggagaATGTTggcaatgctgctgctgctggtcgtcGCGCTGGCGTCaccagtggcagcggcagcggcagcggcagcggcagtcgCATCGGTCGCGCGTCTGATGGTGTGGCTGCTGATGCCGATGGTGGTACATCATCATCTGAGAGcgagtcaacaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAAACAGTAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTACTGCAGTCACATATTAAAAGCCATTTTCTGAATGGGCCCTCggcgggcagcggcagcggcagcgccagcgccagcagaagccacaataataataataacatcgacagcagcagcagcggcggcagcagcggcagcagcagcagcagcagcagcaacaacaaaaccaaaaccaaaaagtcCGGCTTGGATGCAATCAAAAGTGGCAgcgctgcaacaacaacagcaacaacaacaacaacaacaacagttgcagctgaagcagctgcaacaacagcagcagcggacgCTGCAACCAGCTTGAACTGA
Protein Sequence: MVACCSSSKLSTAQHSSARRNDSLDCAPGNDIIIYVGVVVVVGTLLLRVLGAWCWHWAALWFRFGSISCYLNSWQSFKNRCLSSQSKQRQWLDTDKSKQQTLLGYLDLNKTENGSSIEQQQHETNIDSATVAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQLQQQQQLQQQQQQQQQQQQQQQQQQNAARTTSAAAESQQTLQTLLLQVPSAILSTASTQQQQQQQQQRKYQQQQQQRGRQQHYHQQHQQQQQHQQQQQHHQQRLSRIRQPRRQQQAAATSAQRLAKFKPKLCLPLDISVPPLPPLLPPPLPPMLSTIVAGADLAPLPLPLPLDFSQSQCQNPNANQSQKHGSVLPPPPPPPPPLPLAPVAAMTSNASASASATAAAAAAVTTPLLMPPLPAMPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQPLLTRDKVDFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRVKQPNFSHATASGVAVSTDMSAVQEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSSHNNNNNNNAAETPLTSTPKPAASGTAAAATSGGGSTSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEDEESGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTTTSAALAAANRMTPKSLTITATPPLETAAASSAASAAVSAAAAATAATAAATPATSTAAAAAAAASATTTTSTTTAAAAAAAAASGSLPPAMAHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSQPGASDAAKSKASAADLAESSTGTAVPALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDSQQQQQQQQQQQQQQQLQLQQQRGIFKHKTGDDDEEEDDDQLMLLDDGVCVGSSSSNGGGGNAATAAAAAAAASSNANSSTLKIRIPEVACTICGARFTDQEMFSKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSSNSNNNNNNNNSLSSSSMLHLRELHAVGLMPNQQHQKQQQQQQQQQQQQQQQQQQRKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLSCRRCGDLQFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVVVVVAATKPASTATSKNATTKSAATTAAAATGGTKGIIRAGAVRVLKHKQSDELQEQLQDMKVAKRQQSVHVDEEAAAGQEQQQQQQQQDEADDSDMDDDSGDSGDDDEDSTSADDDDDDDDDDDDDEDDEDDEGDVDDDDDDEDIVEQQLLQQQQQQQQQQQQQQSLNSNKNKNNNNNNSVVANEDDDDLIEEVIEDDGIVEELEDDEDDDEDDDDDDDEADGVDDDDDDGNTTDEHQALPSNATKQQQPRRLNFDYTRTDSSKLNGNGKPTPTTTPTPQQHRQKPKGQQAVLVVHSSEDEDADEDAEADVDGDEDVDDDVEEDEEGVGVGEAMTIDDIIEEDDGEDDDDDVVGVDGAVVEDDDDDVEEDMDEDDVDDDDDDDDDDDEENVGNAAAAGRRAGVTSGSGSGSGSGSRIGRASDGVAADADGGTSSSESESTTTTTSHSIGERRKKTVVKSAAHGAAADQSNSSYTCDLCQLCFDSQELLQSHIKSHFLNGPSAGSGSGSASASRSHNNNNNIDSSSSGGSSGSSSSSSSNNKTKTKKSGLDAIKSGSAATTTATTTTTTTVAAEAAATTAAADAATSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00490925;
90% Identity: iTF_00490925;
80% Identity: -