Basic Information

Insect: Drosophila borealis
Gene Symbol: hang
Assembly: GCA_035045885.1
Location: JAWNOR010000405.1:3971622-3986390[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.36 29 5.7 1.0 3 23 488 509 487 509 0.93

2 17 1 84 4.2 3.2 3 22 616 635 614 635 0.89

3 17 0.00077 0.063 14.1 3.3 1 22 737 758 737 760 0.90

4 17 0.089 7.2 7.6 0.1 2 21 772 791 771 792 0.93

5 17 0.0009 0.073 13.9 0.2 2 23 917 939 916 939 0.95

6 17 0.0026 0.21 12.4 0.1 1 23 947 970 947 970 0.96

7 17 0.0002 0.016 15.9 0.2 2 23 1056 1077 1055 1077 0.97

8 17 0.00037 0.03 15.1 2.9 2 23 1200 1222 1199 1222 0.97

9 17 0.029 2.4 9.1 0.2 2 23 1231 1253 1230 1253 0.95

10 17 0.0016 0.13 13.1 0.1 1 23 1266 1289 1266 1289 0.97

11 17 0.00016 0.013 16.2 1.1 1 23 1325 1347 1325 1347 0.99

12 17 0.0025 0.2 12.5 0.9 1 23 1355 1378 1355 1378 0.96

13 17 0.088 7.1 7.6 0.4 2 19 1386 1403 1386 1404 0.94

14 17 9.3e-05 0.0075 17.0 0.4 3 23 1502 1522 1501 1522 0.98

15 17 0.0065 0.53 11.2 0.1 1 23 1557 1579 1557 1579 0.97

16 17 0.00076 0.062 14.1 0.6 2 23 1662 1684 1661 1684 0.93

17 17 0.0083 0.67 10.8 0.3 3 23 1740 1760 1740 1760 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.36	29	5.7	1.0	3	23	488	509	487	509	0.93
2	17	1	84	4.2	3.2	3	22	616	635	614	635	0.89
3	17	0.00077	0.063	14.1	3.3	1	22	737	758	737	760	0.90
4	17	0.089	7.2	7.6	0.1	2	21	772	791	771	792	0.93
5	17	0.0009	0.073	13.9	0.2	2	23	917	939	916	939	0.95
6	17	0.0026	0.21	12.4	0.1	1	23	947	970	947	970	0.96
7	17	0.0002	0.016	15.9	0.2	2	23	1056	1077	1055	1077	0.97
8	17	0.00037	0.03	15.1	2.9	2	23	1200	1222	1199	1222	0.97
9	17	0.029	2.4	9.1	0.2	2	23	1231	1253	1230	1253	0.95
10	17	0.0016	0.13	13.1	0.1	1	23	1266	1289	1266	1289	0.97
11	17	0.00016	0.013	16.2	1.1	1	23	1325	1347	1325	1347	0.99
12	17	0.0025	0.2	12.5	0.9	1	23	1355	1378	1355	1378	0.96
13	17	0.088	7.1	7.6	0.4	2	19	1386	1403	1386	1404	0.94
14	17	9.3e-05	0.0075	17.0	0.4	3	23	1502	1522	1501	1522	0.98
15	17	0.0065	0.53	11.2	0.1	1	23	1557	1579	1557	1579	0.97
16	17	0.00076	0.062	14.1	0.6	2	23	1662	1684	1661	1684	0.93
17	17	0.0083	0.67	10.8	0.3	3	23	1740	1760	1740	1760	0.98

Sequence Information

Coding Sequence: ATGGTTGCCTGCTGCTCGAGTTCGAAACTCAGCACAGAACAGCACAGCTCGGCGCGACGCAACGACTCTCTGGACTGCGCCCCCGGCAACGACATCATCATCTACGTCGGcgtcgccatcgccatcgtcgtcgtcgtcgtcgtcggcacGTTGCTGCTGCGTGTGCTTGGTGCTTGGTGCTGGCACTGGGTTGCTCTTTGGTTTCGCTTTGGCTCGATTTCATGCTATTTGAACTCTTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCCAAGCAGCGGCAATGGCTGGACACCGATAAAAGCAAGCAGCAGACACTTTTAGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCTCCATTGAACAGCAGCACGAAACAAACATCGATTCAGCGACAGTTGCAGCTGAAAAGGCGTCCGCCAACATATTGGATGGCATACCCTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacaacagctacaacagcaacaacaacaacaacaacaacagcagcagcaacagaatgCTGCAAGAACAACGAGCGCGGCGGCGGAGTCACAGCAAACACTGCAGACCCTTTTATTGCAGGTGCCCTCAGCAACATTGTCAACGGCGTCAActcagccgcagcagcaacagcaacaacagcgcaaatatcaacagcagcagcaacgtgGCAGGCAGCAACATTACCaccagcaacatcagcaacaacaacatcagcagcagcagcaacaacatcatcagcagcGACTTAGTCGAATACGTCAACCACGACGCCAGCAACAGGCGGCAACGTCTGCTCAGCGTTTGGCTAAGTTCAAGCCTAAATTGTATTTACCATTGGATATATCAGTGCCGCCGCTTCCACcgttgttgccgccgccgttgccgccaATGTTGTCAACtattgctgctggtgctgatTTGGcgccgttgccattgccgttgTCGCTGCCGCTTGATTTCAGCCAGAGTCAGTGTCAGAATCCGAACGCGAATCAGAGTCAGAAACATGGCAGCGtgttgccgccgccaccgccgccgccgccgctgccgctggctCCAGTTGCAGCAATGTCCAGCAacgcctctgcctctgctactgccactgccactgccgcagccgcagtcaCGACGCCATTGCTCATGCCGCCGCTGCCTGCCATGCCCATCAAGGATGAGCCCATTGACGACACGGATGATGACTTCCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAGCATGGCGTGACGGCGGTTGTGGCGGCGGCATCGCTGCCCGCCAGCGCGGTCGCAAATGTGGCCGCCGCTGGCGACTCCAAGGTGGCCAGCTGCCGTGCCTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGACGCCACGAGCGCAATCTCCATCCGAATCTGTTCCAATTGTCGACAGACTCGCCAAATAATACGCCCATCACAAAACCGACGCCGGCATTGGCAGCCGCGCTGGAGATACAGCGTGCAGCAGCCGCGGCAGCGGCCACCGCGGAGGCAACTAAGGCTGCCGCCGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTCATGAACACGTTCATCAAGTGCGAGAACGGCGGCTTCGACTACGACAATCCGGAACAGTATCAGCCGCTGCTCACACGCGACAAGGTTGACTTCATTCAAGAGAACAACGAGTTTCTGGAGCAGTACCAGACGATGacctgccgctgctgcaacAAATACTTTAACACATACAAGAACTTTATGGCGCACGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATTTATGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGCGTTCTCAACGCTCTCCGCGTCAAGCAGCCAAACTTCTCTCATGCCACCGCATCCGGAGTGGCTGTCTCAACCGATATGAGTGGTGTTCAaggtgccgctgctgctgctgctgctgcaggggCAACAGCACACGAAACATCAATGGAACGGCCAGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAACTGTATGAGTGCAAGCTCTGCCCAAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGATTGGACTTTGCCGATCCCGTAGATCGTCGCCGTCACTACAACAACATGGACTGCATTGTGCGGCTACGCTGCATGACCTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGCGTCAGCAGCGACAATGCGTCCACTGCGAACAGCGGCATGGATCATTCGCCGGGCAAGCGCAGTCTGCTGGGCGCTCTTGGCATTGGTGTCAGTCAGTCATCCAATGATGagtcgcgcagcagcagccacaacaacaacaatgcagtGGAAACACCGCTCACCTCAACGCCGAAGCCAGCTGCATCGGGAACTGCAGCTGCGGCGACCAGTGGCGGCTCCACATCTGGCAATCGCGATGCCCCCAAATCGCAGTATTTTTCCCGCATGCCGCAGGTGTGCCCCATTTGTGGCCAGCagtacaacaactacaacaatgtGCTGCGCCACATGGAGTCAAAGCATCCAAATAAACTGCCCGAAACGTACAAATGTGTACGCTGCGGTCTTGGCTATCCGCGAATCTCATATCTGCGCGAGCACATGATTAATGTGCATGGCGTGGACAAGAATCGGCATTCCGGAGGCTTTGAATATATTGTGAATGCCGATGCTGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACCGGACGCTATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgATGATGAGGACGAGGAAAGCGGCAGCGTTGCCAAAAAGATGCGCCTCgatgacagcagcaacaacagcagcatcaacatGAGTATCGCCAATCAGCAAAAGGAATGCCTCATCTGCAATGCGGTGTTCAGCAACAACATTGGCCTATCCAATCACATGCGCTCGCATTATACCGCCTCCACGACGACGAGTGCAGCGCTGGCGGCGGCCAATCGCATGACGCCAAAGTCACTAACAATTACCGCAACGCCGCCGCTGGAAACGGCTGCCGCATCGTCCACTGCGTCCATTGCGGTgtcagcggcggcggcggcggcggcaacagtAGCAACGCCCGCCACAagcacagctgcagctgccgcagctgcgagtgcaactacaacaacaagtacaacagcagccagcgccgctgctgctgctgctgcctccgcGTCGGGCAGTTTGCCGCCGGCGATGGCACATCAAACGCCACAGGAGCAGGCGGTATTCCGACGTAGCCTGGATCAGGCAGCCGATCGTCGCTTTCGGCGCATGCGCTGTCGCATCTGCCAGCGCAGATTTAGCTCAAAGAAATCGTACCGCTACCACATGCTGACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTTGCCTACGAGAAGGGCCTCAAGGTGCATCTCTTCAAGGTGCACGGACGAGCCATTAAGGACGAGATGATTGTGAAGCAGTTCGAGTGTGATATCTGCTCCATTGTCTACAGCTctgagctggagctgcagcagcacaagCGCAGCGTGCACAAGTCCCAGCTGGGCGCCGCCAGTGATACGGCCAAGTCAAAAGCGTCGGCTGCTGACCTCGCCGAGACCTCCGGCACGGCTGTGCCCGCCCTGCCGCTCTACTGGTACCAGTGCAAGTACTGTCCATCCAATTTCAATACCAACAAAAAGCTGGCCATACACATCAACTCGCACGACGAGTTCGACTCGAACGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGTGGCCGCAAAAGCCTTTGGGTGCATCGCTATAAGAAGCATCCGCAGGTGCCGGATCCCGCTGAGTGCACGCTGTGCCGCAAGATGTTCTTTGACCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCAGGattcgcagcagcagcagcaacagcagctgcaactgcatcAGCAGCGGGGCATATTCAAGCACAAAACGGGCGACGAtgacgaggaggaggatgaTGATCAGCTGATGGTGCTGGACGACGGTGTCTGcgtcggcggcagcagcagcaacggcggcAATGCTGCAACtgtagcagcagctgcagcagcagcatcgagCAATGCGAATAGCAGCACATTGAAGATACGCATACCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTCAGCAAGCATATACAGAAACACGAACAGGATCTCTATGTGGATAATCCATTGGCGGCCATGTTCGATGATGGACCAGCGGATGCTGGACAATTTCAGGTGGAGCGCCAAAACGAGAACGGGGAATACGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAACGctgaacaacagcagcagcagcaacaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTCCATCTGCGCGAACTGCATGCTGTGGGCCTGATGCCCAATCAGCAGCAccagaaacaacagcaacaacaacagcagcagcaacaacagcagcagcagcagaggaaATCGCTGAAACGTAAACGTGAACTGAAATGCGAATATTGCGCATCCACATTcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAACCTGCCGGAGCCGCCAGTGATTGAGGTGGATGAGCCCTTAACCTGTCGCCGTTGCGGCGATCTGCAGTTCGATACCAAGGAGCTGTGGATCGAGCACAAATTGGCCGATGCCAAGGTGGTGCGTCCCTTCTGTCCATTCCAATGGGGCTGCGATCTGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTCATTGTGCCTGTGGCGGTGGCCACCAAGCCAGCCTCAACCGCACCCAGCAagaatgcaacaacaaaatcagcagcaacaacagcaacggcagcggcagcagcaactggaggCACAAAGGGCATAATCAAAGCGGGAGCAGTAAGAGTgcttaaacataaacaatcgGATGAGCTGCAGGAGCAGCTGGACATGAAAGTGGCGAAGCGGCAGCAAAGTGTTCATGTGGATGAGGAGACGGCGgggcaggagcagcagcaggaggaggcgGATGATAGTGATATGGATGATGATAGCGGCGATAGTGGCGAGGATGATGAGGATAGCACAAGCgccgatgatgatgacgacgatgatgatgacgacgacgacgacgaagatgatgatgacgacgatgagGGCGATGTggacgatgacgacgatgacgaagaTATTGtggaacagcagctgctgcagcaacaacaacagcaacaacaacaacaacagtctctcaatagcaacaagaacaagaacaacaataacaacaacagcgtgGTTGCAAATGAGGATGACGATGATCTCATTGAGGAGGTAATCGAGGATGATGGCATTGTCGAGGAGCTAGAAGATGATGAGGATGATGACGAGGACGACGATGAGGCCGATggcgttgatgatgatgacgatggtAACACAACGGATGAGCATCAGGCGCTGCCTTCCAATACCACCAAACAGCAGCCGAGACGCCTTAACTTTGACTACACGCGCACAGACAGCTCCAAGCTGAACGGGAATGGGAaaccgacgccgacgccgcaGCAGCATCGGCAAAAGCCAAAGGGTCAGCAGGCGGTGCTGGTCGTGCACAGCTCAgaggatgaggatgaggaCGCTGAGGCTGATGTCGACAGGGATGAGGATGTGGATGACGATGTGGATGAGGATGAGGAGGAtggggaggaggaggagggcgTGGGTGAAGCAATGACCATTGATGATATTATTGAAGAAGATGATGGGGAGGATGATGACGATGTGGTTGGTGTCGATGGTGCTGTTGttgaggatgatgatgatgatgttgaggAAGATATGGACGAGGATGACGTGGACGACGACGaagacgatgacgacgacgacgacgacgagaaTGTTggcaatgctgctgctggtcgtCGCCCTGGCGTCgccagtggcagtggcagcggcagcggcagcggcagtcgCATCGGCGCGTCTGATAGTGTGGCTGCTGATGCCGATGGTGGTACATCATCATCTGAGAGcgagtcaacaacaacaacaacatcgcaTTCAATTGGCTTACAAATCAAGAACAAGAAAAACGGCACAGATCGGTCGGATATATCCATCCCAGTCTga
Protein Sequence: MVACCSSSKLSTEQHSSARRNDSLDCAPGNDIIIYVGVAIAIVVVVVVGTLLLRVLGAWCWHWVALWFRFGSISCYLNSWQSFKNRCLSSQSKQRQWLDTDKSKQQTLLGYLDLNKTENGSSIEQQHETNIDSATVAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQLQQQQQQQQQQQQQQNAARTTSAAAESQQTLQTLLLQVPSATLSTASTQPQQQQQQQRKYQQQQQRGRQQHYHQQHQQQQHQQQQQQHHQQRLSRIRQPRRQQQAATSAQRLAKFKPKLYLPLDISVPPLPPLLPPPLPPMLSTIAAGADLAPLPLPLSLPLDFSQSQCQNPNANQSQKHGSVLPPPPPPPPLPLAPVAAMSSNASASATATATAAAAVTTPLLMPPLPAMPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQPLLTRDKVDFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRVKQPNFSHATASGVAVSTDMSGVQGAAAAAAAAGATAHETSMERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSSHNNNNAVETPLTSTPKPAASGTAAAATSGGSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEDEESGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTTTSAALAAANRMTPKSLTITATPPLETAAASSTASIAVSAAAAAAATVATPATSTAAAAAAASATTTTSTTAASAAAAAAASASGSLPPAMAHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSQLGAASDTAKSKASAADLAETSGTAVPALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDSQQQQQQQLQLHQQRGIFKHKTGDDDEEEDDDQLMVLDDGVCVGGSSSNGGNAATVAAAAAAASSNANSSTLKIRIPEVACTICGARFTDQEMFSKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSSNNNNNNNSLSSSSMLHLRELHAVGLMPNQQHQKQQQQQQQQQQQQQQQRKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLQFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVATKPASTAPSKNATTKSAATTATAAAAATGGTKGIIKAGAVRVLKHKQSDELQEQLDMKVAKRQQSVHVDEETAGQEQQQEEADDSDMDDDSGDSGEDDEDSTSADDDDDDDDDDDDDEDDDDDDEGDVDDDDDDEDIVEQQLLQQQQQQQQQQQSLNSNKNKNNNNNNSVVANEDDDDLIEEVIEDDGIVEELEDDEDDDEDDDEADGVDDDDDGNTTDEHQALPSNTTKQQPRRLNFDYTRTDSSKLNGNGKPTPTPQQHRQKPKGQQAVLVVHSSEDEDEDAEADVDRDEDVDDDVDEDEEDGEEEEGVGEAMTIDDIIEEDDGEDDDDVVGVDGAVVEDDDDDVEEDMDEDDVDDDEDDDDDDDDENVGNAAAGRRPGVASGSGSGSGSGSRIGASDSVAADADGGTSSSESESTTTTTSHSIGLQIKNKKNGTDRSDISIPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00531093;
90% Identity: iTF_00531093;
80% Identity: -