Basic Information

Insect: Drosophila lacertosa
Gene Symbol: -
Assembly: GCA_004143845.1
Location: SCDZ01000031.1:24124-28034[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00033 0.034 14.8 0.1 1 23 154 177 154 177 0.96

2 14 0.0011 0.12 13.1 2.9 2 23 226 248 222 248 0.89

3 14 0.022 2.3 9.1 1.0 1 23 352 375 352 375 0.93

4 14 1.3 1.3e+02 3.5 5.2 2 23 424 446 423 447 0.95

5 14 0.0026 0.27 12.0 0.5 1 23 507 530 507 530 0.88

6 14 1.6 1.6e+02 3.2 0.1 2 14 549 561 548 573 0.85

7 14 0.00054 0.057 14.1 3.3 2 23 581 603 581 603 0.96

8 14 0.00062 0.065 13.9 0.1 1 23 715 738 715 738 0.95

9 14 5.4e-05 0.0056 17.3 0.3 1 23 790 813 790 813 0.94

10 14 0.00091 0.096 13.4 2.2 2 23 863 885 862 885 0.97

11 14 0.0015 0.15 12.8 2.0 1 23 970 993 970 993 0.92

12 14 0.11 11 6.9 1.5 1 21 1045 1065 1045 1066 0.95

13 14 1.2 1.3e+02 3.6 0.1 2 23 1111 1135 1110 1135 0.84

14 14 7.3 7.6e+02 1.1 0.2 1 8 1153 1160 1153 1177 0.77

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00033	0.034	14.8	0.1	1	23	154	177	154	177	0.96
2	14	0.0011	0.12	13.1	2.9	2	23	226	248	222	248	0.89
3	14	0.022	2.3	9.1	1.0	1	23	352	375	352	375	0.93
4	14	1.3	1.3e+02	3.5	5.2	2	23	424	446	423	447	0.95
5	14	0.0026	0.27	12.0	0.5	1	23	507	530	507	530	0.88
6	14	1.6	1.6e+02	3.2	0.1	2	14	549	561	548	573	0.85
7	14	0.00054	0.057	14.1	3.3	2	23	581	603	581	603	0.96
8	14	0.00062	0.065	13.9	0.1	1	23	715	738	715	738	0.95
9	14	5.4e-05	0.0056	17.3	0.3	1	23	790	813	790	813	0.94
10	14	0.00091	0.096	13.4	2.2	2	23	863	885	862	885	0.97
11	14	0.0015	0.15	12.8	2.0	1	23	970	993	970	993	0.92
12	14	0.11	11	6.9	1.5	1	21	1045	1065	1045	1066	0.95
13	14	1.2	1.3e+02	3.6	0.1	2	23	1111	1135	1110	1135	0.84
14	14	7.3	7.6e+02	1.1	0.2	1	8	1153	1160	1153	1177	0.77

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCGGCAGACTTTGAGGATGCCGACGACCCTGAAATAAACACTCATAACAATGGCAATAACGCGACGGCAGACGAGTTTATGGCCGAAGAGGAGGATGAGGAGCAAGACACTGAGGAGGACAAGAGCAAGCGCAAAGGAAACGAGCCCGATGACGATGCcatatttgattttgagcTGGAACCAATTGTTAGCATTGCTGAACCTGAACCAGAACCTGCGCCTAGACCAAATCCTGCCCCATTAGCGCCTCCAATGCCCACTTCGGTACCAGCATCCATACGCCCAACGCGTCAGTCGCTTGGCTCCACCTCCATGCTGGTGGGTCGTGGAGCTGCCGGCGTTGCACCACCCGCACGGCCAACGACATCGCAAATCAATGCAACTGATGAAAACGGTGTGCCCATTAACTATGAACTGGGCGTCATTTATATATGCCCCGCTTGCGGCGCCGAATATCGGCAACAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAACACACGACGGGGCCTCAATTTCGTGGCCATCGATAAGCTGTACCATCGCTGCCTCGAATGCAACAAACGCATCGCGATGCACAGCCGAGAGAATCTCCTAAAGCACAAGTTCACCCATTTGCCATATCGCTGCACCAAATGCTACATCTGCAAGCGCGAGTACAAGTACAGGCAGGACCTGATGGTGCATCTGCGCATGGTGCACTGCGACGAGGTGGTGGCCATGATGCGCGGCGGCGATTGCCGTGCCGGACGCAAGACTCGTGTGCGCGAGTCACGCGTCGAGCAGCAACACGGTCCCTACGGCCCCGTgcatgacgatgacgatggcaTCGAGGTGAAGAACGAGCTAATGGAAGCGGAGAGCGCTGCCCAAGCCGACGAGTCGAACGTAGGTCTGGACGATGAGCAGAGTCGCAGCTCGAATCAGGCAGCCAAGAAGAAGCGCAGCAATACTGCGGCAGGCAACGGAACTGCCGGTGGTCCGGCGGATATATGCGAGGATTACATACACTACATGTGTCCCGATTGTGACACCGATTGCGATACGCACGCCCAGTGGAGCCAGCATATTGAATTTGTGCACGACTATGTCAGCCGGCGTGGTCTCAACTTTCGTTGCGTGGACATGCAGATGCAGTGCCTCGAATGCGAAGCGttcgTTATCCCAAACACAATTAAGACGCTGCGCGCACATAAGTTCAGCCATTTGGCTAAGCCAGAGTGGATGCGCTGCAAGCTGTGTTATCAGGGCTATACGGAGCACCACGAGCTGGTCACGCATCTGCTCAAGCAGCATCATTTGGAGACTCTAATGCccgagcaggagcaggagcagccgACGGCCATTGCCAGCGCTAATGAGGGCGATGAGTGTGAGGATAATCAGGGCGAGGATGAATCCCTCCTGCAATGGGACGATGTGCCGCGTCGTGGCGGTCGCATTGGCAGCGATGATATATATGAGCCACACATTGATTATTTGTGCCCGCAGTGCGGCAGGGAGTTCATTGAGAAGAAACATTGGCGCACGCATGTTGTGCAAGTGCACGGCATGAATGATCTGGCAAAGCTGAACTTTGAGGTGATCAACGATCGTCAGCTCAAGTGTACCGAATGCGATAAGATTATCACGAACGCCTATGGCATACAGAATGCGCAGCAGCACAGGATTACGCATCTGCCATACAAGGCGTATGCGAGATGTCGCAAGTGCCATAAATCCTATACAGATCGCAAGGGTCTGGTCAAGCACTTGGCCACATACCATCGCGTTGGCTACGAGCCGCGCAAAACAGGCGCGCGCGGTGATGCGGGCACAGGAACAGGATCCACTTTGGGTCTGGGAATGGCACCGTCTAAGCCACAGGCGCCGCGCAAACAAATCGTCACTGTGGCCAACGAAACCTATGAGATTATCTATTTGGATGAGGAGCAATCGCCGCCAagtaacaataatataaacgAAGAGAACGATTTCGGCGAGCAAATGCAGGCGGATGACGACGATTATGCCATAGGCGGCAACAGTGGCAGTGTGGCTCGCCAGCTGCCGGCACTACCAGCTGGCGCAGCTGTCCAGTCCAACGCCAACTCGAATCGCTATAAGTGTGTCGACTGTGGATCTCTGTTTGCCACACAGGCGGCGCTCAAGACGCACATTAGCGAGGAACACGACTTCATGGATACGCAATATAGCGCCAAGAAGTTTGACAATGCCAAGCCCACAGAGGAGACAGCTACCGTTGCAGCCATAACAGCGCCCGCGCTAAGCGCTACGCCTGCGAAGAACAGCGCCGGCGGCTCGACCATCGAGCAGAACTATATATATCTGTGCCCGTCGTGCGGCAAGGCTTACAAGACGCAGTTCGAGTGGCGTCGCCACATCAATGAGGAGCACAATTTCGATAAGCGGCAGTATCTGAACATGCGCCAGCTGGACAAGTATCGCTATCAGTGCACCCTCTGCAAGGACATCGTGTGCAACTCTAAGTTAAAAGGACTGCAGGATCATCATTTTCGCCATTTGCCTTACAGGCTGTATCTGAAGTGTCTTGTGTGCGGCACCTGCTACAATCACAAGCCCAACATTGCAGCACATCTGCGCACGCGGCACAACATCTACGAGCGCGAGTCATCGTGGCGTGACCAACAGCCCAAGCCGCAGAACGGCTACGAGCAAGTGAAGTACAAGGATCGGGATAAGGACACGCAAGCTATATCCGCAACCAGCTCGGCCTCACCCACGCCAGGCAGCAGTCGCACGCTGAAGCCGCAGCCGGGCGTGCTGCCCGCACGGCCAGCCGGCCTTAATACATTGGAGGACAGCATCTCGTATCATAATGCCGTTGATCTCGACTTTATTACCTACTATTGCCCCAAGTGCAACAAGAACTTTGACTCGCACGCCTTCTGGCGTAAACACATCGTGGAACAGCACAACTATAACAGTCGGCAGGGCTTGAACTTTCGCCAGATCGACAACCATCACTATCTGTGCCTGGAGTGCTACAAGCGGGTCACGGTCACCCACACCAAGGGCGCCATCGGGCAGCTGCAGTCGCACAAATTCCGTCATCTGCCCTATCGCTCCTTCAAGTGCTTGACCTGCAGCGGCGAGTTTGTGCGCAAACAAATGTTCTTCAAGCATTTGAACCGGGACACCGATCGCTGCGATAACAAACCGTTGAGTGGACAGGATACCGAGGAGGATGCGGCTGAGCTGCAGCTGGTCGACAGAGCAGCCGTCACGTCCGCCAACGAGATAGTCGACAACGCCGCTTACCGCCTGATGTGTCCGCAGTGTGGCGATGGCTTCACAACCGGCAGCAAAGCCGAGTGGCGGCAGCACATTAATATCTTCCATGGTCTGGGCAAGCGCGAGCTGCTGCATATGCGCAAGCTGGGCGAGGAGCTCTATCGCTGCACAGACTGTGAGGAGCAGCTGCAAACGAAGCAGGTCCGCGTGCTGCAGGAGCATCGTTTCCGCCATTTGCCCTATGCCGCCTACATACGATGCCTGCTGtgcgagcagcagccgccggaCGGGATGGGCCAtggtgccgccgctgccggGCTGCACAGCATGCgagagctgcagcagcatatACGCGATGAGCATCCCCAAGTGGCCGAACAGGATGGGCAACTGCAAGCCCTGCTGgacgaagaggaggaggacgacgatAGCCAATCGGTGGCTAACAATAAGGCGTCGGATAGTGGGCTATAtatgccgctgccgccgcactTGCTGGACGATGATGGCGAAGACATGGAGTTTGAGGAGCAATATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEDADDPEINTHNNGNNATADEFMAEEEDEEQDTEEDKSKRKGNEPDDDAIFDFELEPIVSIAEPEPEPAPRPNPAPLAPPMPTSVPASIRPTRQSLGSTSMLVGRGAAGVAPPARPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDCRAGRKTRVRESRVEQQHGPYGPVHDDDDGIEVKNELMEAESAAQADESNVGLDDEQSRSSNQAAKKKRSNTAAGNGTAGGPADICEDYIHYMCPDCDTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECEAFVIPNTIKTLRAHKFSHLAKPEWMRCKLCYQGYTEHHELVTHLLKQHHLETLMPEQEQEQPTAIASANEGDECEDNQGEDESLLQWDDVPRRGGRIGSDDIYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKTGARGDAGTGTGSTLGLGMAPSKPQAPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIGGNSGSVARQLPALPAGAAVQSNANSNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAKPTEETATVAAITAPALSATPAKNSAGGSTIEQNYIYLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESSWRDQQPKPQNGYEQVKYKDRDKDTQAISATSSASPTPGSSRTLKPQPGVLPARPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTDRCDNKPLSGQDTEEDAAELQLVDRAAVTSANEIVDNAAYRLMCPQCGDGFTTGSKAEWRQHINIFHGLGKRELLHMRKLGEELYRCTDCEEQLQTKQVRVLQEHRFRHLPYAAYIRCLLCEQQPPDGMGHGAAAAGLHSMRELQQHIRDEHPQVAEQDGQLQALLDEEEEDDDSQSVANNKASDSGLYMPLPPHLLDDDGEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: -
80% Identity: -