Basic Information

Insect: Drosophila kurseongensis
Gene Symbol: zfh1
Assembly: GCA_018153305.1
Location: JAECXX010000045.1:107680-111982[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.6e-05 0.0027 18.0 1.1 1 23 140 162 140 162 0.97

2 15 0.00075 0.055 13.9 1.2 3 23 170 190 168 190 0.94

3 15 0.00016 0.012 16.0 0.1 1 23 339 361 339 361 0.98

4 15 0.00012 0.0087 16.4 0.7 1 23 367 389 367 389 0.98

5 15 4.5e-06 0.00034 20.9 2.1 1 23 420 442 420 442 0.98

6 15 0.0038 0.28 11.7 2.0 1 23 472 494 472 494 0.94

7 15 0.0097 0.72 10.4 1.3 1 23 500 523 500 523 0.97

8 15 0.024 1.8 9.2 0.4 3 19 532 548 531 549 0.95

9 15 0.00014 0.01 16.2 5.6 1 23 558 580 558 580 0.97

10 15 0.042 3.1 8.4 0.4 2 23 586 607 585 607 0.96

11 15 8.3e-06 0.00061 20.0 1.0 1 23 616 638 616 638 0.98

12 15 0.00094 0.07 13.6 0.1 3 23 646 666 644 666 0.97

13 15 5e-05 0.0037 17.6 0.5 1 23 672 694 672 695 0.95

14 15 0.033 2.5 8.7 0.3 1 23 705 727 705 727 0.97

15 15 0.005 0.37 11.3 0.2 1 23 1249 1271 1249 1271 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.6e-05	0.0027	18.0	1.1	1	23	140	162	140	162	0.97
2	15	0.00075	0.055	13.9	1.2	3	23	170	190	168	190	0.94
3	15	0.00016	0.012	16.0	0.1	1	23	339	361	339	361	0.98
4	15	0.00012	0.0087	16.4	0.7	1	23	367	389	367	389	0.98
5	15	4.5e-06	0.00034	20.9	2.1	1	23	420	442	420	442	0.98
6	15	0.0038	0.28	11.7	2.0	1	23	472	494	472	494	0.94
7	15	0.0097	0.72	10.4	1.3	1	23	500	523	500	523	0.97
8	15	0.024	1.8	9.2	0.4	3	19	532	548	531	549	0.95
9	15	0.00014	0.01	16.2	5.6	1	23	558	580	558	580	0.97
10	15	0.042	3.1	8.4	0.4	2	23	586	607	585	607	0.96
11	15	8.3e-06	0.00061	20.0	1.0	1	23	616	638	616	638	0.98
12	15	0.00094	0.07	13.6	0.1	3	23	646	666	644	666	0.97
13	15	5e-05	0.0037	17.6	0.5	1	23	672	694	672	695	0.95
14	15	0.033	2.5	8.7	0.3	1	23	705	727	705	727	0.97
15	15	0.005	0.37	11.3	0.2	1	23	1249	1271	1249	1271	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGCGATATGGCGGCATCCAGTGGATACAGCACCACGTCTCCGCTGGCGACTCCTCGGAGGTGGACATCCTGGAGAGTGAAGCCGGAGCGGGGGCGACGGGCGAGGACCTGGACCATATGGCAGCCGAGAATCTTATATTCATGGCGCGAGACGGCCAGCTGAGCGAGATGATGGCTGCCAACGAAGCGGGCGGAACAGTCCTAGTGACTGCCGATGGCACAACGGTGGCCTATGCTGAATCCTTTGACGATGACGCCCAGGTGGTCACGGAGGAAGTCATTACGGACGACTGGGTGCAGCACCAGGGTGCCGAGCGTGTGGAAATCGCCGCCGAGCAGATAGCCGGCATTAGCAGCTCGCAGGAACTGCTGGACATGGAGCAGGATGAGTACACCGCTTTGAGACCCTATCCCTGTGACTTTTGCAGCCGTCGGTTTCGCAAGAAGGCGACCTTAAACAACCACATGCTGGCCCACCAAAACGATCGACCGCATCTCTGCAAGCTGTGTGGAGCCCGATTCTCACGACGGGCAGAGCTTATCAGTCATTTCAAAGCCCACGCAGAGGCCCAGGATGCAGCCGATGCTGAAGCGGCAGCCGCCGCAGCCGATTCCGCCTCATCTATTAAGTTCGAGCACCAGTCGCAGCGGCAATTGGACGATCACTACTACGAACAGGAGTGGCCACTCTACCAACAGCAAGATCAGTCGCAACAGGAGATGCAGCACCACCATCAGATATTGGAGGTGGGCGAGGTTCAGCTACTTGACAGCTATCCGGAAGCAGTAGCTCCGCCCGCAGCACCAACTCGGGGCAGGATCAGTCGGCTTAAGCCCAAGGAGGAGAGCAGCCAGTTTATTGTGATTTCCGACAAGCCGATCGCCAGCGATTTAAGGGACTACATGGACTCTGAGCCGGCTCAGCCTGTGGTTACAACATCGCACCCCATCGCCGTCGAACCTCCGCCACAGCCAAACTTCCCAGTGCTGGATGACAGCAAACCCTTCGTGTGCCAGCAGTGCGGATTGGCCTTTGCGCGGGAAAAGGCACTCGTCGCACACACAAAGAACCACCGCGTGGACTCGCCATTCGAATGTAATCAGTGCCAGGAGATGTTCTGGGACAATAGTAGCCTGCAGGAGCACCAGAAGACGCACCAGTTCGAGGAGAGTAACTCGGAGTACGATCCTGCTTCGGCGGAGGATAGTGCCAGCGAATCGGAGCCCGATGAGCAGTTGTACGGCGAGTTCTATTGCAACGAGTGTGGGATCTCTTTCCATCGCCAGGATCTGCTGCGGCGCCATGCCAAAATGCACTACAAGCAAACAGATCAGGCAGCCGGTGAGGGCAATTCCGATGTGACTGCTGGCGGAGAGATGGAGCTTGCCAAAGATTCAGGCGGCCACTGCTGTCACACCTGCGGAAAGTCGTTTCCCAGCGCATTGGAGATGCTTGCCCATGCCGAAATCCACGCTAGGTTCCCGCCCTTCAAGTGCGTCCTATGCGGAATCAGCTTTTACGAGGAGCAGGCAATAAAGCGGCACCTGCACACCCGCCACCCCAGCGAATTGAAGGCGAACTCCTGCGTGCTATGTGGCAAGGAGTGCCGCGACCGCAAGGCTCTGATTAAGCACGCATGGGACCATTCGCGCGAAAAGTGCCACTCGTGCTCCAAGTGCGGCAAAAACTTTCACAACAAGGCGCGCCTGAAGCGACACATGGCCTCGCATCGCGACAAGTCAGTGGTGTGTGAGGTGTGCCAGGAGGAGTTCCCCGACGGACGAACACTCTCCAACCATCGCCACTCCCACAGCACCACCTCACCGGGCAAGCTCTTTCCGTGCCACGAATGCGGTAAGACGTTTGGATCGCGTAGCTCCCAGCAGATCCATGTGCGCATCCATACTGGTGAGCGGCCATACGGCTGCCGCTACTGCTGGAAGGCCTTTGCCGACGGTGGCACGCTGCGAAAGCACGAGCGCATTCACACGGGCGAAAAGCCGTACGCCTGCTCCGTTTGCCCGCGCGCCTTTAACCAGCGTGTGGTGCTGCGCGAACACATCCGCTCTCATCATTCTGGGCTGGATGTGGCGCGGAATACGTACCACTGCACGGTCTGCTCCGAGGACCTAGCCTCGTCCAACGACCTCATCCAGCATCTCATTCAACACAGTGATTCAAACACCGCCAAGCAGCGCCAGCCCATTACGGGCCCGCGCAAGTACAAGCGGCGACGTAAGCTGCAGCCCCACGAGATCGCACACATGCGGGCGGAGCACAAGGACGCCAACGGCGAAGAGGAGGATGCCATAGGAGGGGGCGATGCAGATGAGTACACTAGCGACATCGACCTTTGTGACTTCGATGTGGATAATGTGGACGATATCTTTGAAATGGCCGAGTCGCCCAAAAAGGAAAAGAGAAAAAGGTCGTCGGGAGCTCCAAAGGCTGAACCCAAACCAGCGGCTAATGGCAAAATGGCGAAGTCGGCCCAGGAAAAGAACAAGGCCAAATCAAGATACGACTCTACCAGCAGTCAACAATCAGATCGCATCTGGGAAGAGAAGTTTCTGCAAGACAGCCAAGTGGCTCTCTTCCAGATCGATTCGTTGGTTGTGGTTAACGATACTCACCTGCAGCCCTCCAGTTCCACTGGACCTGCAGCCGTACCCAAAACAAGGGGAGTCGCCAAGCAGCAGGGAAAAGTGCAGGCTAAGCCTACAGAAGTGTCAGGCAACCTTAATACCTCCGTTTCCGCATCCACCGGCACCTCCTCCACTTCCAGCAGTCGCAGCAGGAAGAAGGCAGGAATTACAAAGACTGCCAGCAAAGCACCACCTGCCAGCAATTCGCGACCCCGAATGATTCACACAGAGAAGGCCAAAGTACCGAAGGGAGCTGGCGGAGAATCATCGAGCAGTGCGGCCAAGAAGACGCGATCCAAGACCTACATCAGTCGAACGGAGACAACTAATCTTAGTCTTGAGAAATCACGCAGCAGTGCCTCAAACATGGTGGATGACTATGAGATCATTTCTCCGGCCACCCATCCACCAAATCAGATCAGCTCCAGCCCTCTGCACATCAAACAGGAGCAGGAGCAGCGTGTTCAACTAATGTACGATGATAATCTCCTGATAGATGCTGGTCTGCTCAGGGAAAAGACGTACGAGAAGTTCAACCCGAGCATTGTTAATCTGGAGGAGATTCTGCGTTCGCCACTAAAGCACGAGAGGAATTCCCGCCTTCGTTTCACCAGCGAATCCTCGACAACCCCGCAATTTCTGCCCGAAGAGGAGCAGAACCTGATTAAGATCGAGCCAACGTCTCCAGACTTGCGGGAGATGGTGGAGAGCCAGCAAAGAGTCACGGCTCCCAGTGGGACCACTCCTTCGTCCTCATCCTCTGCCAGAACTTCCAGACATCTGCGTCAGATCACTGCCAATGGTGCAAGGACAGAGAGCAGGAGGACTGCAGGAGGCATTAACAGCAAATCATCAGCAGGCGCGGGAGTTGCCAAAAAAGTGAACACTGCCATCAAGGTCAGCAGCAGCTCATCCTCGTACCTGAATTACGGGGTGGATGCATACAATGTGAACGTACCTGCCAGCGCGAGCAATGCCGATGTGGGCAGCGGTTTCTTTTCCATCTCGGAGGTCGTCTCCGCTGCTGATGCCGCGGATGCGGCGGCCATGGCGGCGGCGGCTGGTAAATTGGAGCGCAAATCCCGCAGCTTCGAGTGCGAAATGTGCTCGGCCATCTTCTACGATCGCGCCCAACTGCTGGAACATGTGCACATCCACATTTAG
Protein Sequence: MNNQRYGGIQWIQHHVSAGDSSEVDILESEAGAGATGEDLDHMAAENLIFMARDGQLSEMMAANEAGGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKATLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAADSASSIKFEHQSQRQLDDHYYEQEWPLYQQQDQSQQEMQHHHQILEVGEVQLLDSYPEAVAPPAAPTRGRISRLKPKEESSQFIVISDKPIASDLRDYMDSEPAQPVVTTSHPIAVEPPPQPNFPVLDDSKPFVCQQCGLAFAREKALVAHTKNHRVDSPFECNQCQEMFWDNSSLQEHQKTHQFEESNSEYDPASAEDSASESEPDEQLYGEFYCNECGISFHRQDLLRRHAKMHYKQTDQAAGEGNSDVTAGGEMELAKDSGGHCCHTCGKSFPSALEMLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPSELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDANGEEEDAIGGGDADEYTSDIDLCDFDVDNVDDIFEMAESPKKEKRKRSSGAPKAEPKPAANGKMAKSAQEKNKAKSRYDSTSSQQSDRIWEEKFLQDSQVALFQIDSLVVVNDTHLQPSSSTGPAAVPKTRGVAKQQGKVQAKPTEVSGNLNTSVSASTGTSSTSSSRSRKKAGITKTASKAPPASNSRPRMIHTEKAKVPKGAGGESSSSAAKKTRSKTYISRTETTNLSLEKSRSSASNMVDDYEIISPATHPPNQISSSPLHIKQEQEQRVQLMYDDNLLIDAGLLREKTYEKFNPSIVNLEEILRSPLKHERNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTAPSGTTPSSSSSARTSRHLRQITANGARTESRRTAGGINSKSSAGAGVAKKVNTAIKVSSSSSSYLNYGVDAYNVNVPASASNADVGSGFFSISEVVSAADAADAAAMAAAAGKLERKSRSFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605719;
90% Identity: iTF_00515719;
80% Identity: -