Basic Information

Insect: Drosophila kokeensis
Gene Symbol: Znf574
Assembly: GCA_035042145.1
Location: JAWNLT010000264.1:5254699-5256966[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.8 1.8e+02 2.9 2.6 2 23 331 353 330 353 0.94

2 10 0.061 4 8.1 0.1 6 23 363 380 363 380 0.98

3 10 1.5e-05 0.00097 19.4 4.2 1 23 386 408 386 408 0.98

4 10 0.00062 0.04 14.4 0.8 1 23 414 437 414 437 0.93

5 10 0.00065 0.042 14.3 2.8 1 23 445 468 445 468 0.97

6 10 0.16 11 6.7 0.4 3 23 476 497 474 497 0.92

7 10 0.52 33 5.2 0.2 2 23 509 531 508 531 0.93

8 10 0.0013 0.086 13.3 2.2 1 23 538 561 538 561 0.93

9 10 3.7e-06 0.00024 21.4 3.7 1 23 567 589 567 589 0.98

10 10 0.042 2.7 8.6 3.3 1 23 595 618 595 618 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.8	1.8e+02	2.9	2.6	2	23	331	353	330	353	0.94
2	10	0.061	4	8.1	0.1	6	23	363	380	363	380	0.98
3	10	1.5e-05	0.00097	19.4	4.2	1	23	386	408	386	408	0.98
4	10	0.00062	0.04	14.4	0.8	1	23	414	437	414	437	0.93
5	10	0.00065	0.042	14.3	2.8	1	23	445	468	445	468	0.97
6	10	0.16	11	6.7	0.4	3	23	476	497	474	497	0.92
7	10	0.52	33	5.2	0.2	2	23	509	531	508	531	0.93
8	10	0.0013	0.086	13.3	2.2	1	23	538	561	538	561	0.93
9	10	3.7e-06	0.00024	21.4	3.7	1	23	567	589	567	589	0.98
10	10	0.042	2.7	8.6	3.3	1	23	595	618	595	618	0.97

Sequence Information

Coding Sequence: ATGGATGTACCAGTGCCTGAGGAATGCGTGCTATGCCTGGAGGAGAATGCCCTCAGCCTGAACGACTATTTGGACATCTACTCGATAGAGGGCACACGACTGAATGTGGCGAGCATAATCAACAAGCATTTTCCAATGCAGCTGGACGAAAGCAGAGGGGGAGCGCGAAAGATATGTTCACACTGCTGGGGCACTGTGTCCGCATTTAATGCGCTGCACGAGTTCGTCAGCGCCGCGCAGAGTTCGCTGCAGGACGCGAAGGTGCTGCCCATGGAGGATGATCCCTTGACGCAGGGCAACTTCAGCGAGGCACCTAAACAGAATCAGGAGCAAGTCGAACAGAACGGTCGCAATTTCTTCTATCCCGAGGTTAAGATTGAGGAGCATGAGCTGGAACAGCTGCCAAAAATTGAGGTGCTCGAAAGCACGACCAGACAATCGGTGGATGTTGATGCGTCTCCGGTGAGACGATTGCGCAAGCGTGTCAAGGCCGAAGCTGAATCACCAAATATGGAGGCGTGTGATGACAGCAATCAGGATGCGGCCATAACCGCAGAGGCGCCGAAAAAGCGTCGCGGACGACCGCGTAAAATAGACTTAATAATCAAGGACGCGCCAAGTGTCGCGCAAGCTGAACCAACTGTTGACCTAGATGCAGATCTAAAAGCAGAGCCACCTGCCGATTTTAgcgatgatgatcatgatcagGACTTCGCGAGTCAACCCGATGATGGTGTTGCTCGCAGCGATGATAGCAGCGTCGAGGAGAGCTCAGAGAGCGATGATGATTCCGACTTCACGGCGGACAAGCCCAGCGAGAGCGAGTTCGCAGTCATACCGAAGCGAACGGCAGTGCGGCCTAAGAAATACAAGAAGCGTACGAAGCCAGCGGAGCCGAAAGTCCGCAATACTCgtgagcagcaggagcagcgcaagaagcagcaggaggagtTCGATGGAATCATTGCCAAGTTCTTTAACGATGTGTTGCCGTGCTCCATTTGCAATCTGTTGGTCCACAATTTTACGGAAATGCAACGACATCATCGCCTCACACACCAGGTAGATCCGGGCTATGTGATTTGCTGCGGCCGGAAGTTCACGCAGCGCAAGGTGCTGGCGGAGCACGTGCTGGTGCACTGGAATCCGGATCACTTCAAGTGCACAACCTGCGAGAAATCATTCCAAAACTCACGACACCTGGAGTCGCATCAGCAGATACACATGGCCAAACTATCCTTCGAGTGCGATATATGCTCCAAGGTCTTCACCAGCAAAACGGCCATCGAGTACCATAAACTGAACAAACATGTGCCCAAATCCGAATTCAAATTCACGTGCACCGAGTGCAGCAAAAAATTCCTTACCGAACGCAAGCTGAAGAATCACATGAACTCAATGCACGATCCGGAGCGGATAATCATATGCGACAAGTGCGGCAAGCAGATGCGCAccaaaatcattttgaaaaagCATCAGGAGCTCATGCACTCGGACACGCCGCGACCGGAGCCCGAGCTGAAGCAGTGCCAGATCTGCGGCGCCTGGTTGAAGGGGATGACCGGTCTGAAGCAGCACATGAAGAGCATTCACGTGGAAAGCGCCGGCGAGCATCGTTGTAACGTCTGCAGCAAGGTTTCGCCAAATGCCCGCGCCCTGCGTCGCCATATATATCACAATCACGAGTGCGAGCGCAAGTTCAAGTGTACCATGTGCCACAAGGCATTTAAGCGACCCCAAGAACTAAAGGAGCACACATCCACGCACACCGGCGAGGTTCTATATACGTGTCCAAACTGTCCGATGACGTTCTTCTGCAGCGCCAACATGTACAAGCATCGCCAGCGTTTGCATCGGGCACAGTACGAGGCGGACAAGAATCAGCCAAAGCCACCCAATATACTGCAGCAGGCGGTGGGCGCCACAGCCGCCATGAAGATGCAACGCATCCAGCACACGAGTGTGGCCAGCATAGAAACGGACTTGAAGCATTTTTAG
Protein Sequence: MDVPVPEECVLCLEENALSLNDYLDIYSIEGTRLNVASIINKHFPMQLDESRGGARKICSHCWGTVSAFNALHEFVSAAQSSLQDAKVLPMEDDPLTQGNFSEAPKQNQEQVEQNGRNFFYPEVKIEEHELEQLPKIEVLESTTRQSVDVDASPVRRLRKRVKAEAESPNMEACDDSNQDAAITAEAPKKRRGRPRKIDLIIKDAPSVAQAEPTVDLDADLKAEPPADFSDDDHDQDFASQPDDGVARSDDSSVEESSESDDDSDFTADKPSESEFAVIPKRTAVRPKKYKKRTKPAEPKVRNTREQQEQRKKQQEEFDGIIAKFFNDVLPCSICNLLVHNFTEMQRHHRLTHQVDPGYVICCGRKFTQRKVLAEHVLVHWNPDHFKCTTCEKSFQNSRHLESHQQIHMAKLSFECDICSKVFTSKTAIEYHKLNKHVPKSEFKFTCTECSKKFLTERKLKNHMNSMHDPERIIICDKCGKQMRTKIILKKHQELMHSDTPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCNVCSKVSPNARALRRHIYHNHECERKFKCTMCHKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILQQAVGATAAMKMQRIQHTSVASIETDLKHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560591;
90% Identity: iTF_00560591;
80% Identity: -