Dkok013133.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kokeensis
Gene Symbol
RREB1
Assembly
GCA_035042145.1
Location
JAWNLT010000517.1:574155-580792[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.037 2.4 8.8 0.8 1 21 259 279 259 281 0.93
2 13 0.00035 0.023 15.1 0.2 1 23 291 313 291 313 0.98
3 13 0.00026 0.017 15.5 7.2 1 23 319 341 319 341 0.98
4 13 0.92 59 4.4 1.5 2 20 574 592 574 594 0.93
5 13 0.017 1.1 9.8 0.2 1 23 738 760 738 760 0.97
6 13 1.3e-05 0.00083 19.7 0.7 1 23 770 792 770 792 0.99
7 13 0.00087 0.056 13.9 2.0 1 23 798 821 798 821 0.97
8 13 0.0031 0.2 12.2 2.0 1 23 1085 1108 1085 1108 0.95
9 13 9e-05 0.0058 17.0 0.3 2 23 1492 1513 1491 1513 0.97
10 13 0.15 9.7 6.8 6.3 1 23 1519 1542 1519 1542 0.97
11 13 9.8 6.3e+02 1.1 3.4 1 23 1662 1685 1662 1685 0.78
12 13 0.0088 0.57 10.7 0.5 3 23 1745 1765 1743 1765 0.96
13 13 0.0014 0.09 13.2 4.8 1 23 1771 1793 1771 1793 0.99

Sequence Information

Coding Sequence
ATGCTcgccacacagcagcagcaacagcagcaaccacaacagcaacaatcgcacacagcagcagcaactgcagcagcagcaacacaagaGGATGCTCGGGATTTGGGATTAATGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTGCGACAgccgcaccagcagcagcagcagcaacagttgccgctcTCCGatgaggagcaacagcagcagcagctgttggatTCGTCAGCGCAGCGACCGCGTCACAAGCAGCGGCGcagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGCGATTTATCCGAGTCTGGCTTTGTTGATGGTAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataataacaacaataacaatatcaacaacaatatcagtagtagtagtagcagcagtGCAGTCGCtcagtcagcagcaacagcagcgtcgGCAACGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAATTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGCCATATGCGCACCCACAAGCAACATCAGGcctcgcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcaacagcgacgccAGCAACATGCGGGCGGAGCAGGCGCAACTGGTTCGGGATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaacaatagccacaaaacgaacaacaataacaacaccagcaacaacaacaataataataataataacaatgggGATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATTGAGCAGCAAACAGCGACGCCTCAAGGCAGccctaaacaacaacaatataactAGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGATGTGGACAGCGTTGAGAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACTCAATCGCATTCGGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAACTGGaggaccagcagcagcagcacgaggAGGACCACgaacagcagcacaagcaggaGGAACAAGAGCACGCCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCAGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTTCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGCCACATGCGCACCCACAACGGTGACCGGCCATACGAGTGCGCCGTCTGCAATTATGCCTTCACCACCAAAGCGAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGCGAGGAAGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCTCGGACCGATGCCGATATGCTAACCGAGCTGAGTGGCTACCGCTGTCCCACACCCACGGAGCACAGCTCCTCGGCTAGCTCCTCGTCACAACTGAAGCATATGTTGCTGGCGGAGCCGACGCCGGCcgtaaaggcaacagcaacagcagcagcaacagtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCCGCACTAGATCTCAGTATGGATGCGCTCGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcaacaccaacagcagcagcagcaacaacagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCACGCCGCCGCCACCTGCAACGGtagcaactgcagcagacaagtcaatgccaacaaatccagcagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCTTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAACGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagctgccgcagcaatGAGTAAtctcagccagcagcaacagttgcagcagcagcaacagctgcagcattcacattcacaccACGTCCATGCGCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaagcagcagcagcaacaacagttggccaacaacactGGCAACTCTTTGGTGATGGACGATGATGAGCCACCCAAGTTGATTATTGACGAGGATGACGAAGATGTGGAGGGAGaggacgatgaggatgaggaggaggagcaggaatTTGATGTCGATGAGGAGGAACAGGAGGATGAAGAGATGGACTTGGACGatgagcatcagcagcagccgcacgaggaggatgacgatgacgatgatgatgatgatgatgatgctgcagcagcagcaacagaggcgtcgcagcaacaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAGCAGCCGCATACTCAAGCGGAGTCCCTGGGCGGCAATAAGCCGGCGACGCctacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCATATTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacgggaacgggagcgTGAACAGCAACATTTGATCCAACAGTATCGCCAACAAatggccgctgctgcagcggctgctgttgcagttgccgctgTCGCTGCACCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAACACATCAAGCAGCTGCACGCTCATGACTTCgcactgctgctggccaagggGGCCATCGAAACGGATGCACAactgcagcatcaacagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGatgaggctgctgctgtcggcaCCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTTTGGTCAACGGAGGATCTGCGCCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaataacaacacttgccagaacaacaacaacaacaacaataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcggcagcaacagctgcagcagcagcagcagcggcggcggcagcagctgtggcCAGTGGCGATCTAATTGGTAATCTATTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence
MLATQQQQQQQPQQQQSHTAAATAAAATQEDARDLGLMETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQPHQQQQQQQLPLSDEEQQQQQLLDSSAQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNINNNISSSSSSSAVAQSAATAASATQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQSTQQQQQPQSQSQQQQQRRQQHAGGAGATGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNSHKTNNNNNTSNNNNNNNNNNGDELELEDEQLVLSSKQRRLKAALNNNNITRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTQSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEDQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEENKSRTDADMLTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKATATAAATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATVATAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAAAAAAMSNLSQQQQLQQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQQQQQQLANNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQPHEEDDDDDDDDDDDAAAAATEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKASEKQPHTQAESLGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQHLIQQYRQQMAAAAAAAVAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQHQQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAATAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
-