Dkok010061.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kokeensis
Gene Symbol
mod(mdg4)
Assembly
GCA_035042145.1
Location
JAWNLT010000346.1:6703204-6708053[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 5.3e-26 1.2e-23 83.4 0.1 1 100 22 118 22 120 0.93

Sequence Information

Coding Sequence
ATGGCGGACGACGAGCAATTCAGTTTGTGTTGGAACAATTTCAACACAAATCTGTCCGCTGGCTTTCACGAGTCACTATGCCGTGGTGACCTGGTGGACGTATCCCTGGCAGCGGAGGGGCAGATTGTGAAGGCGCATCGTTTGGTGCTCTCCGTCTGCTCGCCCTTCTTCCGCAAAATGTTTACGCAGATGCCAACGAATGCCCACGCCTTTGtgtttttaaataatgttaGCCATTCAGCACTGAAGGACCTGATCCAGTTCATGTATTGTGGCGAGGTGAACGTCAAACAGGACGCATTACCAGCTTTCATTAGCACAGCGGAGTCGCTGCAAATCAAGGGGCTGACAGATAATGATCCACCACCACAGCCGCCACAAGAACCCACGCCCCCACccccaccagcagcaccacaggtacaacaacagcagcaacaacaactcccaGCCCAACGTGTAcagcgtcaacagcagcagcgcgcaACAGCCCGCTACAAGATCGAAACCGTTGACGATGGTCTCGATGACAAGGGCACCACACAAATTGTCATACAGACAACAGCATCGCCACAAGCAACCATcgtacaacagcagcagcaacacatacaaccacaacagcagcagttgcaaacggcgacaacaacaaccgccaCGCTGGTGTCGACAAACAAGCGTAGCGCTCAACGTGGCAGCCAGGGTAGCAGTGGTGCCGTCAAGCGCTCAAAGACAGCATCAACAGCGATATCCGCCAACACTAGCAACGTAATTGACACCCTCGAATCGACAACGGAAActggaacagcaacagcaacatccactcaacaacagcaacatgtgcCACAACAGATAACCGTGCAGACTACTGTAGTGCAGAGCAGCGACACAAAAGTGCgtcagcagcaggcggcacaAGAAGAAGCTGAATACATCGATCTCCCCATGGGTATTCCAACGAAATCGGAACCAGACTATAGCGAAGAGCACGCCGATGTTGCTGGCGATGGCGATACGTCCTATGTTGAAGATGATGCCTATGGCGAGATACGCTACGATGAAAGCTACTTTACCGAAAATGAAGACGCCGGTGCTcagccagcaacaaatacaagcaCCAACGTTGCAGCCACCACATCGAAGGCGGtgggcaaacagcagcaacagtcgcaggCGCAGAGCTACACCGATTCATCGTTTGTCGACACCGGCGGGGATCAAGGCAGCACAGAGGCTCAAGCACCAGGCATCATAAAGTTTATACGCAGCCAGAAGAAGAATGCCCAGTTAGTCTACAAGGGATGCATCTACAACAAGAAATTGACGCAGGCCAACGGCCAGACGACCTGGCGCTGTGCGGATGTGTTAAAACTACGCTGCAAGGCGGTGGTCATCACCAAGAATGGCGAGTTTCTGGACGCACGTCGTCAGCACAATCATGCGTCGCACGACAGTCGCATTGGCGAACGCCAGCTCTACAATGTGGAGGAGGAGCTCGATGAGTACATCGAGATAAGCACATCGAATCCAAAGATATCTCAATAccttaacagcagcaacatcagcatcatgACCGCCAAGGATGGCAAAGAGTGCAAACTGTATGTGCCTGCCTCGGAGGCAACTGAAATCGAAATGCAGGCACTGGTCGACGACTCTGATGACGATGACAGTCATCTAGTGTTCATCGAGAGTCCCTGGTCGACACCGTGTTTGGTGCTAAATGGCTACATGTACAACTGTCACAGTCGTAAGAACAACAAGGAGTACTGGCGCTGTCACAACTACTCCAAAAAAGTGCACGAGCAGCGCTGCCGGTCGCGTTGCGTGCTGGAGAATGGCAAGCTAAAGGGAATAACCGGTGGACTACACAATCATCCGCCTCATACGGAAAAGATTGAGAAAATCATACAGCGAAATCGTCTGGCTGCTGTCAGCACGGGTCGCAACAAGCTAGGACGAGTCCATAGTATTACCCATTTTCAGCAGGAGCAGCCCAAGCAGGAGGTCGAGGAGCACCAGGTATTTGTGCAGCCgcaacaccaccagcaccatATACTTTCCGATGGTACAACTCTGCAGCTAACGGAACACGAGCTGATGCACACCTCGCTGATGCTCATACATGATTAG
Protein Sequence
MADDEQFSLCWNNFNTNLSAGFHESLCRGDLVDVSLAAEGQIVKAHRLVLSVCSPFFRKMFTQMPTNAHAFVFLNNVSHSALKDLIQFMYCGEVNVKQDALPAFISTAESLQIKGLTDNDPPPQPPQEPTPPPPPAAPQVQQQQQQQLPAQRVQRQQQQRATARYKIETVDDGLDDKGTTQIVIQTTASPQATIVQQQQQHIQPQQQQLQTATTTTATLVSTNKRSAQRGSQGSSGAVKRSKTASTAISANTSNVIDTLESTTETGTATATSTQQQQHVPQQITVQTTVVQSSDTKVRQQQAAQEEAEYIDLPMGIPTKSEPDYSEEHADVAGDGDTSYVEDDAYGEIRYDESYFTENEDAGAQPATNTSTNVAATTSKAVGKQQQQSQAQSYTDSSFVDTGGDQGSTEAQAPGIIKFIRSQKKNAQLVYKGCIYNKKLTQANGQTTWRCADVLKLRCKAVVITKNGEFLDARRQHNHASHDSRIGERQLYNVEEELDEYIEISTSNPKISQYLNSSNISIMTAKDGKECKLYVPASEATEIEMQALVDDSDDDDSHLVFIESPWSTPCLVLNGYMYNCHSRKNNKEYWRCHNYSKKVHEQRCRSRCVLENGKLKGITGGLHNHPPHTEKIEKIIQRNRLAAVSTGRNKLGRVHSITHFQQEQPKQEVEEHQVFVQPQHHQHHILSDGTTLQLTEHELMHTSLMLIHD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01326499; iTF_00496711; iTF_01320551; iTF_00511368; iTF_00495214; iTF_00499664; iTF_00576426; iTF_00557280; iTF_00564736; iTF_00593201; iTF_00485939; iTF_00570476; iTF_00558803; iTF_01325750; iTF_00518521; iTF_01321274; iTF_01327978; iTF_01324222;
90% Identity
iTF_00499664;
80% Identity
-