Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: -
Assembly: GCA_035042185.1
Location: JAWNLS010001251.1:12669398-12671659[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 3 2.1e+02 2.7 0.2 1 10 41 50 41 58 0.80

2 10 0.0054 0.38 11.4 5.9 2 23 216 237 215 237 0.97

3 10 0.0005 0.035 14.6 1.5 1 23 263 284 263 284 0.97

4 10 0.0017 0.12 13.0 1.1 1 23 290 312 290 312 0.95

5 10 0.00017 0.012 16.1 0.3 1 23 337 359 337 359 0.97

6 10 2e-07 1.4e-05 25.3 0.8 1 23 365 387 365 387 0.99

7 10 0.0025 0.18 12.4 6.6 1 23 393 415 393 415 0.98

8 10 7.4e-06 0.00052 20.4 0.7 1 23 421 443 421 443 0.98

9 10 2.1e-05 0.0015 18.9 0.1 1 23 447 469 447 469 0.99

10 10 0.0023 0.16 12.5 0.0 3 23 493 514 491 514 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	3	2.1e+02	2.7	0.2	1	10	41	50	41	58	0.80
2	10	0.0054	0.38	11.4	5.9	2	23	216	237	215	237	0.97
3	10	0.0005	0.035	14.6	1.5	1	23	263	284	263	284	0.97
4	10	0.0017	0.12	13.0	1.1	1	23	290	312	290	312	0.95
5	10	0.00017	0.012	16.1	0.3	1	23	337	359	337	359	0.97
6	10	2e-07	1.4e-05	25.3	0.8	1	23	365	387	365	387	0.99
7	10	0.0025	0.18	12.4	6.6	1	23	393	415	393	415	0.98
8	10	7.4e-06	0.00052	20.4	0.7	1	23	421	443	421	443	0.98
9	10	2.1e-05	0.0015	18.9	0.1	1	23	447	469	447	469	0.99
10	10	0.0023	0.16	12.5	0.0	3	23	493	514	491	514	0.96

Sequence Information

Coding Sequence: ATGTCAGCAAACAGTGGAAAAAAGGCTgaggcgacaacaacagcgctGCAATCGCACGTGGAtgccaaaagccaaagcaataTTGATCATTTTATAATTGATACGTGTGCGGATGAACTATATTATTGTGAGGATTGTGGCAATGACTACGACAGCATCGAGGCGTACAATAATGCGCACAGTGGCCTCGGCAGTTGCTCAGGCGCCGTCGAAGCCTGTTCCAAAGTTTCTCTTCATGCCGTCGAGATAAAAAATGAAGCGGACGTCGAAGATGATCGAGGGGATGTTGAATCCCTTATTCTCGAGGATGATCTAATTGAGGAAGTCGACGATGCAAGTGAACCCCAGCTGTGGGAGGTGctcgatgaggatgaggaacTGCTGCCAGCCGAAGTCGAGGACGAAACGCatgctgaagctgctgctgaggctgaggcGGAGCAAAAGTCAGAGCGTTACTTTTGCTTCGATTGCCACAGCATATTCCTGACACTTGAGAGTGCCGAGGAGCACAGCTGCCCCCaggcagaagcaacaacaacaactacaacggGTGGCACACAGAGCAATGTCAAAACGCAGACTCCAGCGCGACGGAAAgtggcaacagccacagcagcagcaagtagcAATAATACGACCActgtttgccacatttgcaaAACCAAATTCAGTTCAGCCAAATGCCTCAAGTTTCACATGCGCATCCACAACAAGCATGCCTCCAAATCAATACAGGATGCATTGCCTGTTGGCGCTCATCAGCAGTACAGCAAACTGGATCAATTTTATTGCGAAATCTGCAACAAGAgCTTCGAAAAAAACCTTTTAACGGTGCACAAACAGATGCATGAGAGCCATCAACAGTTTCTGTGCGCCACTTGCAACCGCCAATTCGATAATCTAACCAACTATAATATGCATCTGAAGATCCATGAACGCCACGcgttgaacaacaacaacaagcccaGTAAAAGGCCCGCCAATGTGGACAAGGATAAGCCTGGATTCGCCTGCCAGTATTGCGAGCGAGTCTTCCCGCGTCCCTATGAGAAGGTGAAGCACGAGCGGGTTCACACCGGCGAGAAGCCCTACAGCTGTGAGGTGTGCGGCAGAACCTTTCGTGTTTCCTACTCCCTCACGCTCCACCTGCGCACGCATACAAATATACGGCCGTATGTGTGCACCACGTGCAACAAACGCTTCAAGTCGCATACGGTTTACTCGCACCATTTGCGCATTCACAGCTCGGAGCGTCAGTATGTTTGTGATAGCTGTCCGAAATCTTTTCGCACTTCCGTGCAGCTCTACGCCCACAAGAATAGTCACACCAAACCGTATCAGTGCGCCGTCTGCAATCGTCCCTTTGCCTCACTGTACGCCGTCAAGGCACACATGTCCACCCACAAAACGAGCGATCCGAAGAGCGCCGGCAAACAGGTCACCAAGAACCAACAAATGTCTAATAAATATTGGTGTGTTACCTGCGGTGCAGAGTACGCACGTCCTTTTGCGCTCCGCCTGCACATGAAGTCTGCCCACGGGCATCAAGATGATGCGGATACACGTTTTGCAAAAATCGCACCAACAGTTGATGACGATGAGATTATTGTTCCTGATACGGAGACGGCGGTGCTTATAGCAGCGGCTAAGGCGGATTCAGCGTATCTGTGTGCTGCGGCCAATGAAGTGGATATTATGGGTGCGGTGCCCAAATACGAGGAATGCATTGAAGTATCATCAGATGCGTTCGATGTGGAAACCTTTCACAACGAGGAGATCATCACCGACTGGCTAAAGTAG
Protein Sequence: MSANSGKKAEATTTALQSHVDAKSQSNIDHFIIDTCADELYYCEDCGNDYDSIEAYNNAHSGLGSCSGAVEACSKVSLHAVEIKNEADVEDDRGDVESLILEDDLIEEVDDASEPQLWEVLDEDEELLPAEVEDETHAEAAAEAEAEQKSERYFCFDCHSIFLTLESAEEHSCPQAEATTTTTTGGTQSNVKTQTPARRKVATATAAASSNNTTTVCHICKTKFSSAKCLKFHMRIHNKHASKSIQDALPVGAHQQYSKLDQFYCEICNKSFEKNLLTVHKQMHESHQQFLCATCNRQFDNLTNYNMHLKIHERHALNNNNKPSKRPANVDKDKPGFACQYCERVFPRPYEKVKHERVHTGEKPYSCEVCGRTFRVSYSLTLHLRTHTNIRPYVCTTCNKRFKSHTVYSHHLRIHSSERQYVCDSCPKSFRTSVQLYAHKNSHTKPYQCAVCNRPFASLYAVKAHMSTHKTSDPKSAGKQVTKNQQMSNKYWCVTCGAEYARPFALRLHMKSAHGHQDDADTRFAKIAPTVDDDEIIVPDTETAVLIAAAKADSAYLCAAANEVDIMGAVPKYEECIEVSSDAFDVETFHNEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00500492;
90% Identity: iTF_00548982;
80% Identity: -