Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: ham
Assembly: GCA_035042185.1
Location: JAWNLS010000945.1:1963545-1988121[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.58 40 5.0 0.0 2 21 335 354 334 357 0.87

2 9 0.015 1.1 10.0 0.1 1 23 364 387 364 387 0.91

3 9 1.8e-07 1.3e-05 25.4 1.7 1 23 393 416 393 416 0.96

4 9 3.5e-07 2.4e-05 24.6 1.5 1 23 422 444 422 444 0.97

5 9 8.8e-05 0.0061 17.0 3.8 1 23 450 472 450 472 0.97

6 9 0.0019 0.13 12.8 2.0 2 21 480 499 479 500 0.94

7 9 6.8e-09 4.7e-07 29.9 1.3 1 23 998 1020 998 1020 0.99

8 9 3.6e-07 2.5e-05 24.5 0.9 1 23 1026 1049 1026 1049 0.97

9 9 4.6e-05 0.0032 17.9 6.8 1 23 1055 1077 1055 1077 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.58	40	5.0	0.0	2	21	335	354	334	357	0.87
2	9	0.015	1.1	10.0	0.1	1	23	364	387	364	387	0.91
3	9	1.8e-07	1.3e-05	25.4	1.7	1	23	393	416	393	416	0.96
4	9	3.5e-07	2.4e-05	24.6	1.5	1	23	422	444	422	444	0.97
5	9	8.8e-05	0.0061	17.0	3.8	1	23	450	472	450	472	0.97
6	9	0.0019	0.13	12.8	2.0	2	21	480	499	479	500	0.94
7	9	6.8e-09	4.7e-07	29.9	1.3	1	23	998	1020	998	1020	0.99
8	9	3.6e-07	2.5e-05	24.5	0.9	1	23	1026	1049	1026	1049	0.97
9	9	4.6e-05	0.0032	17.9	6.8	1	23	1055	1077	1055	1077	0.98

Sequence Information

Coding Sequence: ATGTTATTCGATCGTTATGTTATATCAGGCTCTAACGGCGACGATTACGATCCGAGCGTCGTGCgccatcatcaccatcatcatcaccactTGGATCTCAGCAGTGGGGCGCCGGCATTTGCACCATTGCCGCCGGCGCATCTAACCTCCGGTCAGACGAGGCCCGAGGAATCGTTTGGTCGCCACCTCCCGCCAACGATATCCCCGCCACCAGCAACgctccaccagcagcagcatcaacagcagcagcagcagcatttgcagcaacagcaacagctgcaacattcACCGCCCACGCTGCCGCCTGCCTCAGCACCCGTCTCCAACGGCTCCAGCATGGAGCATCTGTTCAATGACAAAGCGCAGGCGGAACGCTTTCTACTGGAGATGGCGCGTCTGCGCGAACCCGTCTGTGATCTGGATATACGTGATACTGGCGTCTATGCCAAGACACATCTGCCCCGCGGCACCCGCTACGGACCCTTTCCCATGCGTCTCTGCCAGCAGCCCAGCGATCGACACTTGGCCTGGGAGGTGATTGCCGGCCCATTGTTTCACGGGTGGCTGGAACCCTCATCGGATGTGGCCACATGGCTGAAAAAAATACGCGCCGTTCAAAGCGATGAAATCGAAGAGGCTAATTTAAGGAATTTCATCATTGCTGGCTATCTGTGGTACGAGACGAAACGGGACGTAAATGCTGGCGCTGAAATTGTTGTCGATGCCCGTCCGCAAACCCCCTACGACATCAGCGATAGTTTCATGAACGGGGGAGGGGTTGCAGGCGGCGCTGGCAGTGCAACATCGGCGGGGGGCAGCAGTACAGCAGTCGccgcagtggcagcagcagcagcaactgctatGGCAGCGGCAtcatccaacaacaacaacaacggttCGTTGCCAGGCGATGATCGAAGCGATCGTGATAATGGCTTTTACAGCGGAGACGAGAAGAAGGGGGACAACGATTTCACGGACGACGAGAACGGTTTCGATATACGCTGTGAGGTGTGTGATAATGTCTATACGGATTTAGAACGCTTGGATGATCATTTGGTGGGTGCCCATCATTTCAAGCGCGGAGAATTCGCCTGTGAACTTTGCGCCCAGCGCTTCAGCCATCGTCCTCTGCTCATCAAGCACGGAGCCATCGCCCACAACAACATACGCAAATATTCCTGCGAGAACTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGGGCTCGCAGTCATCCGTGTCCGGAGTGCGGTAAAACATTTGCCACATCATCGGGCCTGAAGCAGCATCAGCACATCCACTCATCGGTTAAGCCGTTCGCCTGCGAGGTGTGCTTCAAGGCGTATACGCAATTCTCCAATCTGTGCCGCCACAAGCGGATGCACGCCGACTGTCGCATGCAGATCAAGTGCAAGAAGTGCAACACCAGCTTCAGCACGGTCACCTCGCTGTCCAAGCACAAGAAGTTCTGCGACACCTCCGACAGTTTtcgcagccagcagcagagtCGCCTGCAACACGCCCACGATCGCCACCAtcaccagcatcagcagcagcaactgtcgCAACACTCGCAACATACGCAGCCGTCGTCACTTCTGTTGCCACCCGGTGCCCATCAGCGACTTGCCGCCGAGACGTCAAGTTCGGCCATGGCTACGCCACCAAATCACATTTTTATGATGCGTCCGACGCCGTCGTTCTTTACCGGCTTCCCCAATTACGGGTTCAACGGGCTGTTTCCCGGGTTCCAGCAGGCTGGCAATTTTCCGCTTTCACACATGTTTCCCAATTCGCAGCTGGGCGACATGAGTCGCGGCCTGCCCCCAATTGTCTCGCCAACTGCCGCAttccaacagcagctgcagtcaGCGATGAGCATGAAATCCGGATCGCCACGTTTGAAACGCGACTCCAGCACACCGGAGCGTACGCCCATCAAAACGGAGCTGCATCCCTCCGACGAGGAGGAGTCCGATTCGCTCAGCTACGAGGAGCTCAAGTTGAAGTCCAACAAGTTGCAGCAGGAGTCCGGCAAGGTGAAGCGGGAACTTCAATCGGAGGCCAGTTGCTCCCAGCAAGCCGACGACGACAGCGATCATAACAATAGTGACATTgacaacgataacgataacgacaacgataacgataatgaTAGGAAATCCATTGATATTGTGAGCACTCCGCCGCCAGCGGAAACGCATATGAAAACCGAACCACAAACGGCGGCGGATGTGGACAAGAGCAGCGCTGAGCTGCCACTGGATCTGTCCATCAGTCGCAAGCGACGCAGTTCGCTGTGCAACGCCTCAACGCCCGCCCCGCTGTCCATATCGCTGTCCAGTCGCGAGCCAACGCCCGAGCTGGACgccgaggaggatgaggaggaggaggacgaggacgaaGTGGAGCTGCTAGCGCCGCCGGCAAAGCAACCCAAGCACAGTTCCGGCGAATCGAGCACCTCCCGTCAGTCGTACAAGGGCAGCAGTCCGGTGCCGAGTGCAAGTGCCTCTCCCGGACCCACACCCTCACCCTCGCCACCCATCAGCACTGGGGGTGAGCTGAGCAGCATGTCGGAGAGTGCCGCTGCCaatgcaacggcaacggcaacggcttCAGCGTCGgcagctgccgcagcggcagcagcagcggccgcCTCAGCGATGGCCTGTCCCCGGCAACTGCATCCGCACATGCTGTTTGAGGAGTACTACCGTTCGCGATTCCCAACGCAACCGTTTCATTTTTTAGCCCAAATGGGCGGACGGCCAGGTTTTGAGTCACTTAAGTCGCCAGCGATGGGTGCCGCACATGCGCCCATCAGCGGCGGCGGCTCGCGTCATCTGCCGTTTCCGCCCGAGCATAATTTCCACGAGGCATTCCGTGCCGCTGGCCTGGCGGCCGCTGCCGCCCGTCCGCCCGCAGTGTGCAACACCAGCGGCAAGCTAAAGGATCGCTATACGTGCAAGTTTTGTGGCAAGGTGTTCCCCCGTTCCGCGAATCTGACACGGCATCTGCGCACCCACACGGGCGAACAGCCGTACACGTGCAAGTATTGCGATCGTGCCTTCAGCATCTCCTCGAATCTGCAGCGTCATGTGCGCAACATCCACAACAAGGAGCGACCGTTCCGGTGCCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCATCTGAAGAAGCACGAGGCAGATGCTGGCGGCTTCGAGTACAACGATTCGCCCAGTTCGAATGAGGCCAATGATCGGGACGAGGCCTGCTTCGATGACATCCGTTCGTTTATGAAACGCGTCTATACGCCCACCAGTCTGGGCGGGGCAGATGGGGATACGGAGGAGTATGCCGGCAGTGATGATCAGTTGTCCGTTTCCACGCGACAATCGGCCAACTTTGACAAGGAGCTGCTCTCAAAtggcaacatcatcaacatcaacaacaacaacaacaacagcagcagcaacaataacaataacaacaacaacaatagcaacaacaacaacaatagcaacagcagcagcaacaatcagaCTTTGAACACATCGGAAACAATTGCCGTGAGCACCTAA
Protein Sequence: MLFDRYVISGSNGDDYDPSVVRHHHHHHHHLDLSSGAPAFAPLPPAHLTSGQTRPEESFGRHLPPTISPPPATLHQQQHQQQQQQHLQQQQQLQHSPPTLPPASAPVSNGSSMEHLFNDKAQAERFLLEMARLREPVCDLDIRDTGVYAKTHLPRGTRYGPFPMRLCQQPSDRHLAWEVIAGPLFHGWLEPSSDVATWLKKIRAVQSDEIEEANLRNFIIAGYLWYETKRDVNAGAEIVVDARPQTPYDISDSFMNGGGVAGGAGSATSAGGSSTAVAAVAAAAATAMAAASSNNNNNGSLPGDDRSDRDNGFYSGDEKKGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFACELCAQRFSHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDTSDSFRSQQQSRLQHAHDRHHHQHQQQQLSQHSQHTQPSSLLLPPGAHQRLAAETSSSAMATPPNHIFMMRPTPSFFTGFPNYGFNGLFPGFQQAGNFPLSHMFPNSQLGDMSRGLPPIVSPTAAFQQQLQSAMSMKSGSPRLKRDSSTPERTPIKTELHPSDEEESDSLSYEELKLKSNKLQQESGKVKRELQSEASCSQQADDDSDHNNSDIDNDNDNDNDNDNDRKSIDIVSTPPPAETHMKTEPQTAADVDKSSAELPLDLSISRKRRSSLCNASTPAPLSISLSSREPTPELDAEEDEEEEDEDEVELLAPPAKQPKHSSGESSTSRQSYKGSSPVPSASASPGPTPSPSPPISTGGELSSMSESAAANATATATASASAAAAAAAAAAASAMACPRQLHPHMLFEEYYRSRFPTQPFHFLAQMGGRPGFESLKSPAMGAAHAPISGGGSRHLPFPPEHNFHEAFRAAGLAAAAARPPAVCNTSGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDRDEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRQSANFDKELLSNGNIININNNNNNSSSNNNNNNNNNSNNNNNSNSSSNNQTLNTSETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01327310;
90% Identity: iTF_00513601;
80% Identity: -