Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: Hr39
Assembly: GCA_035042185.1
Location: JAWNLS010000939.1:1299549-1302877[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.88 8.1e+03 -4.1 12.5 28 206 42 211 31 218 0.44

2 3 2 1.9e+04 -9.6 24.6 22 133 209 323 190 364 0.31

3 3 1.2e-101 1.2e-97 328.0 12.3 1 408 495 884 495 884 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.88	8.1e+03	-4.1	12.5	28	206	42	211	31	218	0.44
2	3	2	1.9e+04	-9.6	24.6	22	133	209	323	190	364	0.31
3	3	1.2e-101	1.2e-97	328.0	12.3	1	408	495	884	495	884	0.89

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAACAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAAAACATGTCGACGGCGACACTGACGCCAGCGTCgccgcatcagcagcagcagcgtcacaATGTGTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCAACGCCAACGAATGGCAACCTGGTGCCGGTTATAGCCAactataataatcataatcacaatcacaatcacaatcataGCGGCAGCTTGCGCATTCCCCTCGGTGGCAACGGGGACGAGTCCGATTCGGATGCGGAGTTGGCCAACATTGAGAATCTGAAGGTGCGAAGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGCCGGCGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcagcagcagcagtgccacAACGATGGCCAGCAGTCAGGTGAACGCCATGTTGCAACCCATCAAAACCGAACTGGAGCACATAGCCGGTgagatgcaacagcagcagcagcaacaacagcaacaacagcagcagcagcagcaacaacagcagcaacatcagcagcagcaccaactgcaacaccaacaactgcagctgcagcaacaacaacaattgctgccaCTGAAGCAACAAAGCTATGCACCGAACAACAAACTGAAACTGGCTCCGACGCAAAGTGATCCCatcaatttgaaatatgagccaacgacaacgacaacatctTCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCCATTTGCCACTGTTGCCCGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTATACGCCCTCGCTGAGCAGGAACAACAGCGATGCGTCGCACAGTAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCAATTCAGGCGCGTCATGCGCCACCCGCCGGCGTTGCTGCCTTGTTTAGCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTCAGCATGGATGCGGGTGGTGCTGCATTGGATGCCAGTGCAACGTTGGCTGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTGATCAATTCGCCGTGTCCGATTTGTGGGGACAAGATCAGTGGCTTCCATTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgtggcgGTCCCTGCCAGGTGAGCATCTCGACTCGCAAAAAGTGTCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCAGAGGCGGTCGCTCCACCTATCAATGCTCTTACACACTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCGGCAGCCgctgcagccgccgccgccgttgtcaatcagcaacagcagcagcagcaacaccaacagcagcgacttcaacagcatcagcagcagcagcaacaacagcagcaacagcagcaacatggtCCACTCAATGGctttggtggtggtggctccAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAAACGGAGCAGCTTAATCATCATACGTCATCATCAACGCGAGCCTCAAGCATTCCACCTCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCGTTTGCAACTGGTGGCTCATCGTCGAGCGGCACAGGCGGTTCAAGCTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCCTCCAATGGCGAGAACGCCAATCCCGATCTGATTGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTTTTCAAGAACATCTCGATTGACGATCAGATTTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGATCCGTCGATACGCCCGGCGAGATCAAGATGTCACAGGGCCGAAAGATTACGCTGGCACAGGCTAAAACCAATGGTTTGCAGGCGTGCATTGAGCGGATGTTGAATCTGACCGATCATTTGAGACGACTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACCACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTCTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAATTTGGTGAGCTGCTCCTGCGTATACCCGATCTGCAGCGCACGTGTcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGAGcagattttaatttgctgATGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATLTPASPHQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAAGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQHQQQHQLQHQQLQLQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFSGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQQQQHQQQRLQQHQQQQQQQQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTEQTEQLNHHTSSSTRASSIPPLLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00525176;