Basic Information

Insect: Drosophila insularis
Gene Symbol: -
Assembly: GCA_018903935.1
Location: JAEIFP010002303.1:6072878-6076842[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0009 0.071 13.6 0.7 1 23 536 558 536 558 0.99

2 7 0.0072 0.57 10.8 3.7 1 23 566 588 566 588 0.97

3 7 0.00022 0.018 15.5 1.0 1 23 597 619 597 619 0.98

4 7 1.6e-06 0.00012 22.3 1.2 1 23 673 695 673 695 0.97

5 7 0.00065 0.051 14.1 1.0 1 23 703 727 703 727 0.98

6 7 1.8e-07 1.4e-05 25.3 2.1 1 23 733 755 733 755 0.98

7 7 0.00022 0.017 15.6 0.1 1 23 761 783 761 783 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0009	0.071	13.6	0.7	1	23	536	558	536	558	0.99
2	7	0.0072	0.57	10.8	3.7	1	23	566	588	566	588	0.97
3	7	0.00022	0.018	15.5	1.0	1	23	597	619	597	619	0.98
4	7	1.6e-06	0.00012	22.3	1.2	1	23	673	695	673	695	0.97
5	7	0.00065	0.051	14.1	1.0	1	23	703	727	703	727	0.98
6	7	1.8e-07	1.4e-05	25.3	2.1	1	23	733	755	733	755	0.98
7	7	0.00022	0.017	15.6	0.1	1	23	761	783	761	783	0.98

Sequence Information

Coding Sequence: ATGAGCGTGCTGGCATATACGCGTTCGAACGATGAGGAGATTTTTCGCCATTGCACAAAGGATTGCGGCGTGGTAACGGCCACCGAGGACTTTCAGTATTTTGCCCTAAGATGCATATTCTGTAGCGAGAAGTTTCTTTATTTCGATGCCTTCATTGGCCATTTGCAGACAATACATTTGAGTGATGCCAATGGGAACGATGGCAATGAGGGAAATGAAGTGAGTGGTGGTGGTGTTGGTGGCCAGAGATTAGGTGGTGGCGCTGTTGGACTTAGCCAGCCCATGTCATTATCGATAGGACCATCGCCCGGGGAACATGATGAGATTGAAGACTTAACCGATGCAGATACAGCTCTATTGGAGCCACAAATGGTGATCAAACAGGAGCTACAGGAATTGGGGAGCAGCGATGATGAGGAATCCCCATTGGCTGCGGATACCACAACAAAGAAACGTCTGGCCGCCAATGTCCAGGCATCGGATGAGGCTGAGAACGATGTCGATGACGAGGACGAGGATGTTGATGAGGAAGATGAGGAGGACGATGCCGAAGAGGAGGAGGAGGAAGATGACGAGGATGATGAAGTCATACTGCCGGAAACAAATATATTACCACATCCACGAATGAAGGTAACCAAACCAAGGCCAAAACAGCAGCAGCAACAACGCCAGCGACGACAACAGAAACAAATGGGCGTCAAAAATGAACCACTCACAGCTGATGGCGATTCCTCCATGGATGACTATGGAGGTTATGTGGATGATGACAATGACAATTCCACCGAATATATGGAATACAGTGGTGGACCCGGTTACAATGATCTAACTCAAGGTCACAGCATTTTGGGTACTGGCGGTGCAAATGATTTCCTCAGCTATGATGAAATGGTCGAGGAATCTCTACTAGGCCGAGATCGTGAATTAACCATGCACATTAAAGATCGCAAAATGATACAATTCCTCATCCATTCATATCAACGGAATCCCTTCCTCTGGGATCACAGTCATCCGCAGTTCAGGGATCGTGTGAAACGTGCCAGATTTCTAGACTGGATTGTCCTAGAATTCAAAAGTCGCTTCAACATCTCATTGGCCAAGGATGCCATCACCAGGAAATGGGATAATCTTCGCACCGTTTACAAGCGTGAATGCAATCGGATGGCTCTGGAGAAAACAAATATCAGTACATTATGGTATTTCAAGGAACTGCATTTTCTCAATGAAGTCTATAGTTACAATTCCAAAATGTCTGATGCTGTGGTCAAGGAAACATCATATCGCCGTCGCTTTTCGGCCATTTGGAATGACACATCGACCGCCAAATTGTTGAGTATGGTGAAGCGTTATCATTGCTTTTACAATCGCTTCGATCCGGATTATCGCAGCAAGGAGCGACGCGGCGAAGGTCTCCATCAGATGGCCATGGAGCTGCAACAATTGATCGATGTGACAACGATACAGATATCGAAACGTATATCCCAATTGCGATTCGATTATTCCAAACAGAAGACAGAGCGTTTGAATTGTGAGCGCATGGGTAAAACGTTTATACCGAATTACATATATTACGATCAAATGAACTTCATGGACGACGATATACCGCCATTCAAGTGCCAGCATTGCGGCGAGATAGTGCAGACATTGCGCGAATTGGATCTGCATATGCTGACGCATCAGCCCAGTTTGGGTGGCGGCTACTATTGTAATATCTGTCACATACAATTCCATAATGCCGAGGAGTTTGAGACGCACAAGCAACTCCATTTGGGTGCCGGCAATGAGGTGAAGTACAATTGTGAATTGTGTACGGCCAGTTTTCGTGAGAAATCCAATTACGATGAGCATCTGCGTCGGCACAATGAGGAATTGTTTTTGCCCTCGCTGGGAATCAATCATAGCATTATGGAGGGGCATGAGGATGGCGATATATCTGGCACAGCTGGCGAGGGCGGCGATGATGGCGATGGTGATCAATTGATGACATCACCCGAATCGGGAGGCGGTGGCAATAAGCCATTTCCCTGCGACATCTGTCATCGCACGTTTGCCACATCGGGCCACCTCAATGCCCATCGCATTGTGCATCAGGATGAGCGCGAGCGGTGCTATAAATGCGACTATCCGCAGTGCAACAAATCGTTTGTGGCACGCAATAGCCTGTTCGAGCATTTGAAACAACATTACAGCAACGAGGAATTCAAATGCGATATATGCGGCAAGAGTTTCAAGTCCACCAAGAATTTGCAGAATCACAAACAGATCCATGACAAGGTGAAGCGGTATGTATGCCAAATTTGCGGTTCGGCCTTTGCCCAGGCGGCGGGACTCTATCTACATAAGCGAAGGCATAATCGTCCCAATGGAACAACCGGTGCAGTTGGCCGCTCTGGCGGCAGTCGATCGAGTCTATGA
Protein Sequence: MSVLAYTRSNDEEIFRHCTKDCGVVTATEDFQYFALRCIFCSEKFLYFDAFIGHLQTIHLSDANGNDGNEGNEVSGGGVGGQRLGGGAVGLSQPMSLSIGPSPGEHDEIEDLTDADTALLEPQMVIKQELQELGSSDDEESPLAADTTTKKRLAANVQASDEAENDVDDEDEDVDEEDEEDDAEEEEEEDDEDDEVILPETNILPHPRMKVTKPRPKQQQQQRQRRQQKQMGVKNEPLTADGDSSMDDYGGYVDDDNDNSTEYMEYSGGPGYNDLTQGHSILGTGGANDFLSYDEMVEESLLGRDRELTMHIKDRKMIQFLIHSYQRNPFLWDHSHPQFRDRVKRARFLDWIVLEFKSRFNISLAKDAITRKWDNLRTVYKRECNRMALEKTNISTLWYFKELHFLNEVYSYNSKMSDAVVKETSYRRRFSAIWNDTSTAKLLSMVKRYHCFYNRFDPDYRSKERRGEGLHQMAMELQQLIDVTTIQISKRISQLRFDYSKQKTERLNCERMGKTFIPNYIYYDQMNFMDDDIPPFKCQHCGEIVQTLRELDLHMLTHQPSLGGGYYCNICHIQFHNAEEFETHKQLHLGAGNEVKYNCELCTASFREKSNYDEHLRRHNEELFLPSLGINHSIMEGHEDGDISGTAGEGGDDGDGDQLMTSPESGGGGNKPFPCDICHRTFATSGHLNAHRIVHQDERERCYKCDYPQCNKSFVARNSLFEHLKQHYSNEEFKCDICGKSFKSTKNLQNHKQIHDKVKRYVCQICGSAFAQAAGLYLHKRRHNRPNGTTGAVGRSGGSRSSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00556070;
90% Identity: iTF_00571401; iTF_00612311; iTF_00618648; iTF_00503488;
80% Identity: -