Basic Information

Insect: Drosophila insularis
Gene Symbol: L
Assembly: GCA_018903935.1
Location: JAEIFP010002299.1:3099179-3105917[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.1e-06 0.00071 19.9 2.9 1 23 171 193 171 193 0.98

2 17 0.31 25 5.6 6.2 1 23 199 221 199 221 0.97

3 17 1.5e-07 1.2e-05 25.5 3.2 1 23 227 249 227 249 0.99

4 17 1.1e-05 0.00087 19.6 0.4 1 23 255 277 255 277 0.99

5 17 0.072 5.6 7.7 0.1 2 21 355 376 354 377 0.88

6 17 0.0008 0.063 13.8 0.4 2 23 384 406 383 406 0.96

7 17 0.016 1.2 9.7 0.8 1 23 478 500 478 500 0.97

8 17 0.039 3.1 8.5 0.1 2 23 508 529 507 529 0.91

9 17 3.9e-05 0.0031 17.9 0.2 1 23 537 560 537 560 0.93

10 17 8 6.3e+02 1.2 1.6 2 23 596 618 595 618 0.91

11 17 0.0023 0.18 12.4 1.1 1 23 669 692 669 692 0.97

12 17 0.0044 0.35 11.5 1.2 2 23 855 877 854 877 0.96

13 17 0.1 8 7.2 0.1 1 23 883 905 883 905 0.92

14 17 2.8 2.2e+02 2.6 1.8 2 23 913 934 912 934 0.95

15 17 0.66 52 4.6 0.5 2 23 1047 1068 1047 1068 0.94

16 17 0.0053 0.42 11.2 0.0 1 23 1078 1101 1078 1101 0.96

17 17 0.00021 0.016 15.6 1.2 1 23 1108 1130 1108 1130 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.1e-06	0.00071	19.9	2.9	1	23	171	193	171	193	0.98
2	17	0.31	25	5.6	6.2	1	23	199	221	199	221	0.97
3	17	1.5e-07	1.2e-05	25.5	3.2	1	23	227	249	227	249	0.99
4	17	1.1e-05	0.00087	19.6	0.4	1	23	255	277	255	277	0.99
5	17	0.072	5.6	7.7	0.1	2	21	355	376	354	377	0.88
6	17	0.0008	0.063	13.8	0.4	2	23	384	406	383	406	0.96
7	17	0.016	1.2	9.7	0.8	1	23	478	500	478	500	0.97
8	17	0.039	3.1	8.5	0.1	2	23	508	529	507	529	0.91
9	17	3.9e-05	0.0031	17.9	0.2	1	23	537	560	537	560	0.93
10	17	8	6.3e+02	1.2	1.6	2	23	596	618	595	618	0.91
11	17	0.0023	0.18	12.4	1.1	1	23	669	692	669	692	0.97
12	17	0.0044	0.35	11.5	1.2	2	23	855	877	854	877	0.96
13	17	0.1	8	7.2	0.1	1	23	883	905	883	905	0.92
14	17	2.8	2.2e+02	2.6	1.8	2	23	913	934	912	934	0.95
15	17	0.66	52	4.6	0.5	2	23	1047	1068	1047	1068	0.94
16	17	0.0053	0.42	11.2	0.0	1	23	1078	1101	1078	1101	0.96
17	17	0.00021	0.016	15.6	1.2	1	23	1108	1130	1108	1130	0.97

Sequence Information

Coding Sequence: ATGATGGCTCTAAAAATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTAATTGAAAAGATTCAGGCCACCAAGGAGATAAATACTAACGATATGTACAGCACTCACACCTCTTCGAGCTATTCGCCCAGCATTTCGGATGGAACCCTGACACCCAATTCCCATCATCACTTGCCCGCCTCGGCCGTATCCGGCCTATCTGAGGATCACGAAACAGGACACAAGGCCCATGGAGACCGTGACCAAAAGGATCCTGCGCAGCTATTTAAGCCCAAGCGTCCCTCACATTTCCATCATCATCATCACCATCACTACCATCATCAGCAGGCTCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAAGAGGCCAACAAAATGGGTTCAGGCGGTGGCACTGGCGCCACCGAAGATGGAGGAACTGGCATTGGAGGCGTCTCCTCGGATGCCACCGCAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGCCGAGGCGACGGTTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTGCAGAGCCATGCCGAACATCTGCCATTCAAGTGCGAGTACTGTGCCAAGCTGTTCAAGCACAAGCGTTCCCGAGATCGTCATAAGAAACTGCATACAAATGAGCGAAACTACAAGTGTCCGCATTGCGAGGCGGCATTTTCGCGAAGCGATCATCTGAAGATTCACATGAAAACCCATGACATCCAGAAGCCATTCCAATGCAGCATGTGTAATCGTGGCTATAACACGGCAGCCGCTCTGACCTCGCACATGCAAAAGCATAAGAAGAATGCCGCCATTTTGGCTGCTGGGGGCAATCCTAATGCCCTTAACTACAGTCCGAGATCAACGGGCTCCGCATCCGTGTCTTCGAGTAATAGCAGTCTGCACAAGCGTCGCTATGCCCTGGCTTTGGCCAATAATGACAGCAGTAGTCGCAGTCCAAGTCGTTTGGATTATCCGAAACGTTCCAGGATCACGAATACAAACCAATCTACACCCACTCCCCTGCTAAGGTGCAGCTACTGCCCAAAAGTGACAGAGTTCAGTAGTCTAGAGCAATTGAATGCCCACTTACAAAAGCCAGAGTCCTTCGAGCTGAACTGTGAGTACTGCACCATGAAATTTGGCAACATTGCGGGACTTTTCCAGCACATGAGGACCACCCATTTGGACAGGCTCAGTTCGCCACCATCCATTGCCAGCTACTATGAGCACCTCAATCGCCTTGAAATGCCCAAGCAGATCAAGCAGGACTTGTCTAGTCCACAGCGGAAGGCGGAAGAGCCAGAGGAACTTCCCACAGACTTGAGTAGCAACAAAAGACAGATGGAGGAGCCAACCCAAGCTCCAACCACCGGACATGTCCCACCACCAGGTGTTTTCTTCTGCAACCAATGCAATGCTGGCCTGCCGGACTTTGACAGCTTTCGCAATCATCTAAAGACTCACATAGCCGAAGGAATGCAATTGATATGTCCACATTGTGGGCTCACTTTGCCAGAACAACAGGAATACGAGCGTCATGTGGTTGCCCATTTCTTGATCACCAACTCAGAGTTTAATTGCAGTAGTTGCGGCAAGAGTTTTGCCAAAGCTGAAGATCTGCAGCAGCACTTACTGGCCGACCACGTCGTGACCATTTTGAAGTGCTCCTTGTGCTCGGAACTATGCGAAAATCGCATGGCCATGCAGTTGCATCTGGCCTGTGCCCACAGCCAGGAAACAAAGCTATTGAGATGCAGTGCCTGCATGGAGCTCTTCCGTTCTGATTCAGAGTTCCATGTACATGTGAAGACACGTCATCAATTAGCCCTGGGCAATCAAACAAGCAGCGGTCTGGGATCAGTGTCCAGTGGTGTGAGCCCAACCAATCCTCTCCAGTGCATGTTTTGCCGTGCCGTTTGCTCCTCAGAGCTAGAGATGCACTTCCATTTAGCGGCACATGCTCGACAGTTCCGTTGTCCTTCTTGCCCGGAAACATTTCATGTCGAGTTCTTGCTGGACAGGCATATGCAGAGCCAACATGGTGGGGTGAAGGACAACAAGGAGCAGTCCTCCCCCAATATGGGCATGGGAAGTCTGTATGTGAATGCCTTGTTGCCTCCTCTGGCTGCCGCTGCCGCAGCAGCTGTAACCAACAACAACAACAGCATTATTGACTACAACGTGGCCTTCAAATTCAAGGGTCTCTTTGGCGGCGCGGGAGGAGGCCCACCCACAGCGCCATCCAAGTTCTACAGCCCCCTGCAAGTAGATACAAAAGCACAGCAGCCCTCACCCCACCCGGCACTGATGTACGGATTGAGTCAGAGATATCTCATGGAAATGTACAAGGCCAAGTCCATTTCACCCGCTCCGACCGCTTCCACAGAGCCACCGCAAGGATCTGCAGCAGCACCACCCCCGACCACCTTCAGTTGCGGTATGTGCGAGCGTCAGGATCTTCGCAGCGAGGCTGAACTCCACTCCCATCGCAAGTTGGCCCACAATCTCAAAACCGGAGTCAGTCTACGTTGTGCGTACTGCGCCGGTAATTTCAAGTCCAGGGCCGAACTGGAGCAGCACATGAAGAGCTGTCACAACTCGACGGGCAAGCACAAATGCCTAATTTGTGACGAGATATTTCCCTCACCCGCGATCCTGGCCGAACACAAGTTGCAGCACTCCAAGGTGGGACAGTCGGGCAAGTGTTCCCACTGTTCGCATCAGTTGGAGGATGTGGCCGCCTTTCGCAATCACCTCACAGAGCACGGAAGCGATGGAAGCCTGCCGCTGGCCTGCATTTGTTGCCGCCAAACTCTGCACTCTGAATTCGAATTGTCGTTGCATGCCAAATTCCACACCAAATCATCGGCAGGCACTTCTAGAGGCAGCCTCCAGGAGCCAGTGTGTGCCTTGTGTCTTGAGCCGCTTCCGCCCACTGGACCGCCAATTGATGGTCACATCCCTGCCAAACTATGTGAGAAGTGTTTGCGTAAACATAATTTGAATGGCAAAAGAAACAAGCTAACGGAGTCGCCTTCGGTCAATGTGGCTCCGGCGACTGCGACGGCAGTTGCTCCCAACCATCCCCCCTTTCTAGAGAATCGGTGTAATCTATGCAAAATGATTTTGCCCCATGCCCAAAAACTCCAGGAACATCTGGTTGAGCACACTTTTGCTGGCACCGAACAGCGTGGATTCAATTGCTACATTTGCTCGGCAGTGTTCACTGCTCCAGGAGGACTTCTTAACCATATGTCCGTGGAGCATGGCGCCCACTCGCGACCCTATGATTGCAACTTGTGCCCGGAGAAATTCTACTTCCGAGCTGAGCTAGAACACCACCAGCGAGGACATGAATTGAGACCAGCCCCTCCGACTCGCCTATCTTTGAGTAAGCAAGAGCCGCCCTGTACCCTAGGCAGTCCAAGTCTTAGTCCCACAACGGTTAAACTTGAGCTCTACGAATCGGAAACTCAAGCCTCTGATGTTGACAATGGCGAGGAGGGGACGACTAACGCTACCCAGGAAGAGGAGGAGTACATCGAAGTGGAGCAAATGCCTCATGAGACGCGATCGGAGGAGATAATGGAACGGTCTAGCAACAGCTCTTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEINTNDMYSTHTSSSYSPSISDGTLTPNSHHHLPASAVSGLSEDHETGHKAHGDRDQKDPAQLFKPKRPSHFHHHHHHHYHHQQALKIANKLRKINKEANKMGSGGGTGATEDGGTGIGGVSSDATAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASVSSSNSSLHKRRYALALANNDSSSRSPSRLDYPKRSRITNTNQSTPTPLLRCSYCPKVTEFSSLEQLNAHLQKPESFELNCEYCTMKFGNIAGLFQHMRTTHLDRLSSPPSIASYYEHLNRLEMPKQIKQDLSSPQRKAEEPEELPTDLSSNKRQMEEPTQAPTTGHVPPPGVFFCNQCNAGLPDFDSFRNHLKTHIAEGMQLICPHCGLTLPEQQEYERHVVAHFLITNSEFNCSSCGKSFAKAEDLQQHLLADHVVTILKCSLCSELCENRMAMQLHLACAHSQETKLLRCSACMELFRSDSEFHVHVKTRHQLALGNQTSSGLGSVSSGVSPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDNKEQSSPNMGMGSLYVNALLPPLAAAAAAAVTNNNNSIIDYNVAFKFKGLFGGAGGGPPTAPSKFYSPLQVDTKAQQPSPHPALMYGLSQRYLMEMYKAKSISPAPTASTEPPQGSAAAPPPTTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSHQLEDVAAFRNHLTEHGSDGSLPLACICCRQTLHSEFELSLHAKFHTKSSAGTSRGSLQEPVCALCLEPLPPTGPPIDGHIPAKLCEKCLRKHNLNGKRNKLTESPSVNVAPATATAVAPNHPPFLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMSVEHGAHSRPYDCNLCPEKFYFRAELEHHQRGHELRPAPPTRLSLSKQEPPCTLGSPSLSPTTVKLELYESETQASDVDNGEEGTTNATQEEEEYIEVEQMPHETRSEEIMERSSNSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618656;
90% Identity: iTF_00503471;
80% Identity: -