Basic Information

Insect: Drosophila equinoxialis
Gene Symbol: L
Assembly: GCA_018150345.1
Location: JAECWI010000600.1:3844145-3850957[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.6e-06 0.00076 19.9 2.9 1 23 171 193 171 193 0.98

2 17 0.33 26 5.6 6.2 1 23 199 221 199 221 0.97

3 17 1.6e-07 1.3e-05 25.5 3.2 1 23 227 249 227 249 0.99

4 17 1.2e-05 0.00093 19.6 0.4 1 23 255 277 255 277 0.99

5 17 0.011 0.91 10.2 0.2 2 23 355 379 354 379 0.92

6 17 0.00084 0.067 13.8 0.4 2 23 404 426 403 426 0.96

7 17 0.017 1.3 9.7 0.8 1 23 498 520 498 520 0.97

8 17 0.041 3.3 8.5 0.1 2 23 528 549 527 549 0.91

9 17 4.1e-05 0.0033 17.9 0.2 1 23 557 580 557 580 0.93

10 17 8.4 6.7e+02 1.2 1.6 2 23 616 638 615 638 0.91

11 17 0.0024 0.19 12.3 1.1 1 23 689 712 689 712 0.97

12 17 0.0047 0.37 11.4 1.2 2 23 875 897 874 897 0.96

13 17 0.11 8.6 7.1 0.1 1 23 903 925 903 925 0.92

14 17 3 2.4e+02 2.6 1.8 2 23 933 954 932 954 0.95

15 17 0.69 55 4.6 0.5 2 23 1067 1088 1067 1088 0.94

16 17 0.0056 0.45 11.2 0.0 1 23 1098 1121 1098 1121 0.96

17 17 0.00022 0.017 15.6 1.2 1 23 1128 1150 1128 1150 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.6e-06	0.00076	19.9	2.9	1	23	171	193	171	193	0.98
2	17	0.33	26	5.6	6.2	1	23	199	221	199	221	0.97
3	17	1.6e-07	1.3e-05	25.5	3.2	1	23	227	249	227	249	0.99
4	17	1.2e-05	0.00093	19.6	0.4	1	23	255	277	255	277	0.99
5	17	0.011	0.91	10.2	0.2	2	23	355	379	354	379	0.92
6	17	0.00084	0.067	13.8	0.4	2	23	404	426	403	426	0.96
7	17	0.017	1.3	9.7	0.8	1	23	498	520	498	520	0.97
8	17	0.041	3.3	8.5	0.1	2	23	528	549	527	549	0.91
9	17	4.1e-05	0.0033	17.9	0.2	1	23	557	580	557	580	0.93
10	17	8.4	6.7e+02	1.2	1.6	2	23	616	638	615	638	0.91
11	17	0.0024	0.19	12.3	1.1	1	23	689	712	689	712	0.97
12	17	0.0047	0.37	11.4	1.2	2	23	875	897	874	897	0.96
13	17	0.11	8.6	7.1	0.1	1	23	903	925	903	925	0.92
14	17	3	2.4e+02	2.6	1.8	2	23	933	954	932	954	0.95
15	17	0.69	55	4.6	0.5	2	23	1067	1088	1067	1088	0.94
16	17	0.0056	0.45	11.2	0.0	1	23	1098	1121	1098	1121	0.96
17	17	0.00022	0.017	15.6	1.2	1	23	1128	1150	1128	1150	0.97

Sequence Information

Coding Sequence: ATGATGGCTCTTAAAATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTAATTGAAAAGATTCAGGCAACCAAGGAGATAACTGGTAACGATATGTACAGCACTCACACCTCTTCAAGCTACTCGCCCAGCATTTCAGATGGAACCCTGACACCCAATTCCCATCACCATTTGCCCGCCTCGGCCGTATCCGGCTTGTCTGAGGATCTGCAAGCAGAACACAAGGCTCATGCAGAGCGTGACCAAAAAGATCCTGCACAGCTATTTAAGGCCAAGCGTCCCTCACATTTCCATCATCATCATCATCATCACTACCATCATCAGCAGGCTCTGAAAATTGCCAACAAGTTGCGCAAAATCAATAAAGAGGCCAACAAACTGGGTTCAGGCAGTGGCACTGGCGCCGCCGAAGACGGAGCAACTGGCATTGGAGGCGTCTCCTCGGATGCCACCACAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGCCGAGGCGACGGTTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGTTACTTGAAGCATCACGTGCAGAGCCATGCCGAACATCTACCATTCAAGTGCGAGTACTGTGCCAAGCTCTTCAAGCACAAGCGTTCCCGAGATCGTCATAAGAAACTGCATACAAATGAGCGAAACTACAAGTGTCCGCATTGCGAGGCTGCATTTTCGCGAAGCGATCATCTCAAGATCCACATGAAAACGCATGACATCCAAAAGCCGTTCCAGTGCAGCATGTGTAATCGTGGATATAATACAGCAGCCGCTCTAACCTCGCACATGCAAAAGCACAAGAAGAATGCCGCCATTTTGGCTGCTGGGGGCAATCCTAATGCCCTCAACTACAGTCCGAGATCAACGGGTTCCGCATCGGTGTCTTCGAGTAATAGTAGTTTGCACAAGCGTCGCTATGCCTTGGCTTTGGCCAATAATGATAGCAGTAGTCGGAGCCCGAGTCGTTTGGATTATCCAAAACGTTCAAGGATCACAAACACAAACCAATCTACACCTACTCCTCTGTTAAGATGCAGCTACTGCCCCAAGGTAACAGAGTTCAGTAGTCTAGAACAATTAAATGCCCACTTGCAAAGTGTCCATGAACATCAGCAGCAGCAGCAGCAACAACAGGAACAACAGCAACAACAAACAGAGCCAGAGTCCTTCGAGCTGAACTGTGAGTACTGCACCATGAAATTTGGCAACATTGCGGGACTTTTCCAGCACATGAGAACCACCCATTTGGATAGGCTTAGTTCGCCACCATCCATTGCCAGCTACTATGAGCACCTCAATCGCCTAGAAATGCCCAAGCAGATCAAACAGGACCTGTCTAGTCCACAGCGGAAAGCAGAAGAGCCAGAGGAACTACCAACAGACTTAAGTAGCAACAAAAGACAGATGGAGGAGACAACCCAAACTCCTGCCGCCGGTCCTGTCCCACCTCCAGGTGTTTTCTTTTGCAACCAATGCAATGCAGGTCTGCCGGACTTTGACAGCTTTCGCAATCATCTAAAGACTCACATAGCCGAAGGAATGCAATTGATATGTCCACATTGTGGGCTCACTTTGCCGGAACAACAGGAGTACGAGCGTCATGTGGTTGCTCATTTCTTGATCACCAACTCAGAATTTAATTGCAGTAGTTGCGGCAAGAGTTTTGCCAAAGCTGAAGATCTGCAGCAACATTTACTGGCCGACCATGTCGTGACCTTATTGAAGTGCTCCTTGTGTTCGGAACTATGCGAAAATCGCATGGCCATGCAGTTGCATCTGGCCTGTACCCACAGCCAAGAAACAAAGCTGTTGAGATGCAGTGCCTGCATGGAGCTCTTCCGTTCTGATTCAGAGTTCCATGTACATGTGAAGACACGTCATCAATTAGCCCTGGGCAATCAGAGCAGCAGCGGTCTGGGATCCGTGTCCAGTGGTGTGAGTCCAACCAATCCTCTCCAGTGCATGTTTTGTCGTGCCGTTTGCTCCTCGGAGCTAGAGATGCACTTCCATTTAGCGGCACATGCTCGACAATTCCGTTGTCCTTCTTGTCCGGAAACATTTCATGTCGAGTTCTTGTTGGACAGGCATATGCAGAGCCAACATGGTGGGGTGAAGGACAACAAGGAGCAAACCTCACCCAATATGGCCATGGGAAGTCTATATGTGAATGCATTGTTGCCTCCTCTGGCTGCCGCTGCCGCAGCCGCTGTAACCAATAACAACAACAACATTATTGACTACAACGTGGCCTTCAAATTCAAGGGCCTCTTTGGCGGTGGGGGAGGGGGCCCACCCACAGCGCCATCCAAGTTCTACAGCCCCCTGCAAGTAGATACAAAAGCACAACAGCCATCACCCCACCCGGCACTGATGTACGGACTGAGTCAGAGATATCTTATGGAAATGTATAAGGCCAAGTCCATTTCACCCGCTCCGCCCACAAGCACAGAGGCACAGCCGGGATCTGCGGCAGCACCACCCCCAACCACCTTCAGTTGCGGTATGTGCGAGCGTCAGGATCTTCGCAGCGAGGCTGAACTTCACTCCCACCGCAAGTTGGCCCACAATCTTAAGACCGGTGTCAGTCTACGTTGTGCATACTGTGCGGGTAATTTCAAGTCCAGAGCCGAACTGGAGCAGCACATGAAGAGCTGTCACAACTCGACAGGCAAGCACAAATGCCTAATTTGTGACGAGATATTCCCCTCACCCGCAATCCTGGCCGAACACAAACTGCAACACTCTAAGGTGGGACAGTCGGGCAAGTGTTCGCACTGTTCGCATCAATTGGAGGATGTGGCCGCCTTCCGCAATCATCTCACAGAGCACGGAAGCGATGGAAGCCTGCCGCTGGCATGCATTTGTTGTCGCCAAACTCTGCACTCTGAGTTCGAATTGTCCTTGCATGCCAAGTTCCACACGAAATCATCGGCAGGCACTTCTAGAGGCAGCCTCCAGGAGCCTGTGTGTGCCTTGTGTCTTGAGCCGCTTCCGCCCACTGGACCACCAATTGATGGCCACATCCCTGCCAAACTATGTGAGAAGTGTTTGCGTAAACATAATTTGAATGGCAAAAGAAACAAACTAACGGAGTCGCCTTCGGTCAATGTGGCTCCGGCGACCGCGACGGCTGTTGCTCCCAACCATCCCCCGTTTCTAGAGAATCGGTGTAATCTATGCAAAATGATTCTGCCTCATGCCCAAAAACTTCAAGAGCATCTGGTTGAACACACTTTTGCTGGCACCGAACAGCGTGGATTCAATTGCTACATCTGTTCGGCAGTGTTCACTGCCCCCGGTGGACTTCTTAATCACATGTCGGTGGAACATGGTGCCCACTCGCGACCCTATGATTGCAACTTGTGTCCGGAAAAATTCTACTTCCGAGCTGAGCTAGAACATCACCAGCGAGGACATGAATTGCGACCAACGCCTCCGAGTCGTCTATCCTTAAGTAAACAAGAGCCGCCCTGTACCCTAGGCAGTCCAAGTCTTAGTCCCGCAAATGTTAAACTTGAGCTCTACGAATCGGAAACTCAAGCCTCTGATGTTGACAATGGCGATGAAGGAACGACCAACGCTGCGCAGGAAGAGGAGGAGTACATTGAAGTGGAACAGATGCCTCATGAGACGCGATCGGAGGAGATAATGGAACGGTCTAGCAACAGCTCTTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITGNDMYSTHTSSSYSPSISDGTLTPNSHHHLPASAVSGLSEDLQAEHKAHAERDQKDPAQLFKAKRPSHFHHHHHHHYHHQQALKIANKLRKINKEANKLGSGSGTGAAEDGATGIGGVSSDATTKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASVSSSNSSLHKRRYALALANNDSSSRSPSRLDYPKRSRITNTNQSTPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEHQQQQQQQQEQQQQQTEPESFELNCEYCTMKFGNIAGLFQHMRTTHLDRLSSPPSIASYYEHLNRLEMPKQIKQDLSSPQRKAEEPEELPTDLSSNKRQMEETTQTPAAGPVPPPGVFFCNQCNAGLPDFDSFRNHLKTHIAEGMQLICPHCGLTLPEQQEYERHVVAHFLITNSEFNCSSCGKSFAKAEDLQQHLLADHVVTLLKCSLCSELCENRMAMQLHLACTHSQETKLLRCSACMELFRSDSEFHVHVKTRHQLALGNQSSSGLGSVSSGVSPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDNKEQTSPNMAMGSLYVNALLPPLAAAAAAAVTNNNNNIIDYNVAFKFKGLFGGGGGGPPTAPSKFYSPLQVDTKAQQPSPHPALMYGLSQRYLMEMYKAKSISPAPPTSTEAQPGSAAAPPPTTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSHQLEDVAAFRNHLTEHGSDGSLPLACICCRQTLHSEFELSLHAKFHTKSSAGTSRGSLQEPVCALCLEPLPPTGPPIDGHIPAKLCEKCLRKHNLNGKRNKLTESPSVNVAPATATAVAPNHPPFLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMSVEHGAHSRPYDCNLCPEKFYFRAELEHHQRGHELRPTPPSRLSLSKQEPPCTLGSPSLSPANVKLELYESETQASDVDNGDEGTTNAAQEEEEYIEVEQMPHETRSEEIMERSSNSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618656;
90% Identity: iTF_00618656; iTF_00612306; iTF_00523914; iTF_00571380;
80% Identity: -