Basic Information

Insect: Drosophila insularis
Gene Symbol: RREB1
Assembly: GCA_018903935.1
Location: JAEIFP010002303.1:2103865-2110633[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.022 1.7 9.3 0.8 1 21 116 136 116 138 0.93

2 14 0.0002 0.016 15.7 0.2 1 23 148 170 148 170 0.98

3 14 0.25 20 5.9 0.5 1 14 176 189 176 192 0.89

4 14 0.97 76 4.1 0.3 2 23 218 240 217 240 0.92

5 14 0.44 35 5.2 6.3 2 19 246 263 246 265 0.97

6 14 0.025 1.9 9.1 0.0 1 23 440 462 440 462 0.97

7 14 7.5e-06 0.00059 20.2 0.7 1 23 472 494 472 494 0.99

8 14 0.0005 0.04 14.4 2.0 1 23 500 523 500 523 0.97

9 14 0.0018 0.14 12.7 2.0 1 23 696 719 696 719 0.95

10 14 5.2e-05 0.0041 17.5 0.3 2 23 978 999 977 999 0.97

11 14 0.088 6.9 7.4 6.3 1 23 1005 1028 1005 1028 0.97

12 14 7.5 5.9e+02 1.3 6.1 1 23 1166 1189 1166 1189 0.87

13 14 0.0051 0.4 11.3 0.5 3 23 1254 1274 1252 1274 0.96

14 14 0.00081 0.064 13.8 4.8 1 23 1280 1302 1280 1302 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.022	1.7	9.3	0.8	1	21	116	136	116	138	0.93
2	14	0.0002	0.016	15.7	0.2	1	23	148	170	148	170	0.98
3	14	0.25	20	5.9	0.5	1	14	176	189	176	192	0.89
4	14	0.97	76	4.1	0.3	2	23	218	240	217	240	0.92
5	14	0.44	35	5.2	6.3	2	19	246	263	246	265	0.97
6	14	0.025	1.9	9.1	0.0	1	23	440	462	440	462	0.97
7	14	7.5e-06	0.00059	20.2	0.7	1	23	472	494	472	494	0.99
8	14	0.0005	0.04	14.4	2.0	1	23	500	523	500	523	0.97
9	14	0.0018	0.14	12.7	2.0	1	23	696	719	696	719	0.95
10	14	5.2e-05	0.0041	17.5	0.3	2	23	978	999	977	999	0.97
11	14	0.088	6.9	7.4	6.3	1	23	1005	1028	1005	1028	0.97
12	14	7.5	5.9e+02	1.3	6.1	1	23	1166	1189	1166	1189	0.87
13	14	0.0051	0.4	11.3	0.5	3	23	1254	1274	1252	1274	0.96
14	14	0.00081	0.064	13.8	4.8	1	23	1280	1302	1280	1302	0.99

Sequence Information

Coding Sequence: ATGCTAGCAACAACAACAACAACAACATCTACTGATATGGAACGTCAACAAGATGCCGATGAAGAGGAGTCTGCCAATGCTGCAGCTGCGCACCAACAGCAGCAGCAACAGCAACGCCCACGCCATAAACAGCGACGGAACGGCTCTGTTGCCGCCGCTGCCAGCGCCAGCATTGTAATCGATGGCCCAGCCGATGCCAATTCACTGCGCAAGAAATTCCGTTTGAATCGCAGCAATAGCAGCAGTCTAATCAATGGCGAACTATCCGAATCGGGCTTCGTCGATGGCAGCGCACACAGCCTTTGCATGTCATCGTCCAGTGCTGGCGGCGATGAGCACATGAAATATCTATGCCCCATCTGTGAGGTTGTCTCGGCCACGCCCCATGAGTTTACCAATCACATCCGATGTCATAATTATGCCAATGGCGATACCGAAAATTTCACCTGTCGCATTTGCTCCAAGGTATTATCCTCAGCCTCATCTTTGGATAGGCATGTTCTGGTACATACAGGTGAACGACCCTTTAATTGTCGCTACTGCCACCTGACATTTACCACAAATGTGGAAGTATCTATTACTAGTACACCAGATGTTGCCGCTCTATTGGCTGGTGCCTCGAGATCAGCATCACCCACAACTCCACTGATAAGTTGCCCTGTCTGTTTATCTGAATTCGAATCCCTGCCCAGTTTATGCCAACATTTGGACCAACAACATTCCGATATATTGGCCAAATGTCGTGAATGCGATGTGATCTTTTCGAGTCACAAGCAACTGCAGAAACATTGCTGTCGTGGTGGTTCATCGTCCAGTGGATTGCCGCCCCTCCTAAGAGCGAGTAGCTCACCATTGCATGGCGAACAAGAAGACGACGACGACGACCTCGATCGAGATGCGGACGATGATGATCGAGAGATGAGACGTCATGCCGTGGACACCATGGACCATCGCGATGAAGTCAAGGTGGAGAAGGAAGCCGAAGCCGAGGCCAAACAGCGTGACGATTTCTTTCATCATTTGTATTTGAAGAGCAAAACCGAACATGCCCAGATGTCCGAGGATAACAACGAGCTGGCCACATCGCCACCATCGCCCATAAAGCATGAGCCGAACGATAGCAAAGATCTGGCCGACATACAAAGCATCCTGAATATGACCAGTTCGAGTTGTACATCCAGTTTTCTGCGCAACTTTGAGCAATCGGTCAATACGCCATGCTCTTCGAGCCAATACAGTCTAGATGGACGGGATCAGGAGGAGGAGGCCCAGGATGTCTTCACCTCGGAATTCCGTCGCATGAAATTGCGTGGCGAATTCCCCTGCAAACTGTGTGCGGCAGTTTTCCCCAATTTGCGTGCCCTCAAGGGGCACAATCGTGTCCATTTGGGTGCAGTTGGACCCGCTGGTCCCTTTCGTTGCAACATGTGTCCGTATGCGGTGTGCGACAAGGCCGCTTTGGTGCGGCACATGCGCACCCATAACGGAGATCGTCCGTATGAGTGCGCCGTCTGCAATTATGCCTTCACCACCAAGGCGAATTGTGAGCGCCATTTGAGGAATCGTCATGGCAAAACCAGTCGTGAGGATGTCAAACGTGCCATTGTCTACCATCCGGCCGAGGATGCCAGCTGCGGCGAGGGTGAGGGTAAATTGCGTTTAAACGACACCGATGAGAGTTATCGTTCGGCATCGCCGCCACCTCTGGAGGTGACTGCTGCCTCCCAATTGAAGCATATGCTGATGAACGATGGCCCAGGAGTTACGCAAAATGTGCAACAGCCGCCGCCACTTAAGATCCAAGTTAAGAGCCTCGATCAGTTGGTGGAGAAGCAAACACCTGCCATTAAGGCGACGCCGTCGCCAGCAGCAACTCCGCCGCCACCGTCAACATCGTCGAACGGCTCAGTCGTTGGAGAGAAATTGCCACCGTCCAGTGCCATGCAACAGCAGCAGCAGCAACAACAAATGAGCCCCTCAAGCAACCGTCTATCCCTGCTGCCCGGTGGCCCAGTCAAAATGGTCATCAAGAATGGTGTCCTTATGCCCAAGCAGAAGCAACGTCGCTATCGCACCGAACGTCCCTTTGCCTGTGAGCACTGCTCGGCGAGATTTACCTTGCGCTCGAATATGGAGCGACATGTGAAGCAGCAACATCCACAGTTCTATGCCCAGCGCCAGCGAAGTGGCCACCATGTGAAATATGCCATATTGGCCCAGCAATTGAAGGCACACAAGAACACAGATTTGCTGCAACAGGCATTGGCCCATGGATCGAGCAGTGTGGCCGCAGCGGCAGCTTCTTCTCACTTGATGAACTTCAATTATGCCCTGGCCAATGGAAATGGCAACACAGCAGCTGCTCACGTGGATGTGGATATGGACAAAAAGCTGGTGGTAATTGTGGATGATGACCAGCAATCGCATGACAAAGATTTGCCACAAACCATTGAGAACATGGCCAGCAATGAGGCAGCCAAGAAGGTGGCCGAAACCATTCTAGAGCAGGCCATCAAAGCTGGTAAACCCACAAGCCATGAGGTGGAATCAGCTTCCGCTGCAATTGCCAGTAGCCATCAGGCGCCATCCTCAATGAAGTCGATGATTGCTCAAGTTGAATCCGTGGCCAAGTCACTGAAAGATGTGGCCAGCTCACCGTTCAATAAGGATGAATCTCCACTCTCCGATTTGGTGCCCGTATCCAAGCTAGTGGACAATGCCACAAGCAATCAATCGATGCAAAGTTTCACCAGTTATTTTCGTCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAAGAGGGTCTCGTTGCCTCGGGCAGTGCCAGCGAGAGCAATAACTCAGGCACCGAGGATGTCACCAGCAGCAGCAGCAGTGGCCAAGAGCCCAAAAAGAAATCCGCCTACAGTCTGGCCCCCAATCGTGTCTCGTGCCCCTATTGCCAGCGTATGTTCCCCTGGAGCAGTTCCCTGAGGCGGCACATTTTGACCCACACCGGCCAGAAGCCATTCAAATGCTCCCACTGTCCGCTGCTCTTTACCACCAAGAGCAATTGTGATCGTCACTTGTTGAGGAAGCATGGCAATGTCGAATCGGCCATGTCCGTGTATGTCCCCACCGAGGATGTGAGTGAACCGATACCGGTGCCCAAATCAGTGGAAGAAATCGAATTGGAGGAGCAACGCAAGCGCCAAGAGGCCGAGCGAGAGAAGGCCGAACTGGAGCGAGAACGCGAGCGAGAGCGTGAACTTGAGCGTGAGCGAGAACGTGAAAGGCAATTGGAGCGAGAGAGGGAAAAGGAGCTAGAACGTGAGCGAGAACGAGAACTGGAATTGGAGCGAGAGCAGCAGTTAATGCAACAATTGGCTGCCGCTGCTCAATTAACTCAGCAAATGGCCGTGGCTGCCTCTTCGTCGGCAGCAGCAGCAGCCGCTGCAGCCGTCGCTGCCGCAAATTCAGCGAGTAACGAGTTGGCCAATGGCGATTTGCCCTTCAAGTGCCATCTGTGTGAATGTTCGTTTAGCGAGCGTTTGCAGTGCTTGGATCACATCAAGCAAGCGCATGCCCATGAATTTGCCTTGCTTTTGGCCAAGGGAGCCATCGAAACGGAAGAACCCCTCCAGGGAGCAAACGCAACAGCGGCAGCAGTGCAGCCCACTGCTCCCCAATCCGATGATGAAGGATCTTTGGGTATGGCCGGCAATGGTCGTGGTGGTTCTGGTAAATACCCCGACTATAGCAATCGGAAAGTGATTTGCGCATTTTGTGTTCGTCGCTTTTGGTCCACTGAGGATTTGCGTCGTCATATGCGTACCCATTCGGGTGAGAGGCCATTTCAGTGTGAGATTTGTCTACGCAAATTCACATTGAAGCATAGCATGTTGCGGCACATGAAGAAGCATAGTGGACGTTCCCATAATGCTGGTGAGATGCAAGAGAATTTGGGCGAGCAACAACACCGTGCAACAACTCCGGGAGCAACTGCATCTGCTGTGGCTGGTTCAACCGATCTCATTGGCAATCTGTTGGGCATCAGTGATCAGGGTATATTGAATAAATTGCTCTCATCCGCTGATGAGGCAGCCAAATTTCTGGGAGTGGACAAGTAA
Protein Sequence: MLATTTTTTSTDMERQQDADEEESANAAAAHQQQQQQQRPRHKQRRNGSVAAAASASIVIDGPADANSLRKKFRLNRSNSSSLINGELSESGFVDGSAHSLCMSSSSAGGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNVEVSITSTPDVAALLAGASRSASPTTPLISCPVCLSEFESLPSLCQHLDQQHSDILAKCRECDVIFSSHKQLQKHCCRGGSSSSGLPPLLRASSSPLHGEQEDDDDDLDRDADDDDREMRRHAVDTMDHRDEVKVEKEAEAEAKQRDDFFHHLYLKSKTEHAQMSEDNNELATSPPSPIKHEPNDSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCGEGEGKLRLNDTDESYRSASPPPLEVTAASQLKHMLMNDGPGVTQNVQQPPPLKIQVKSLDQLVEKQTPAIKATPSPAATPPPPSTSSNGSVVGEKLPPSSAMQQQQQQQQMSPSSNRLSLLPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVKYAILAQQLKAHKNTDLLQQALAHGSSSVAAAAASSHLMNFNYALANGNGNTAAAHVDVDMDKKLVVIVDDDQQSHDKDLPQTIENMASNEAAKKVAETILEQAIKAGKPTSHEVESASAAIASSHQAPSSMKSMIAQVESVAKSLKDVASSPFNKDESPLSDLVPVSKLVDNATSNQSMQSFTSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGQEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRKRQEAEREKAELERERERERELERERERERQLEREREKELERERERELELEREQQLMQQLAAAAQLTQQMAVAASSSAAAAAAAAVAAANSASNELANGDLPFKCHLCECSFSERLQCLDHIKQAHAHEFALLLAKGAIETEEPLQGANATAAAVQPTAPQSDDEGSLGMAGNGRGGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGEMQENLGEQQHRATTPGATASAVAGSTDLIGNLLGISDQGILNKLLSSADEAAKFLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00503516;
90% Identity: -
80% Identity: -