Basic Information

Insect: Drosophila insularis
Gene Symbol: Hivep1
Assembly: GCA_018903935.1
Location: JAEIFP010001763.1:1554275-1562752[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 9.9e-05 0.0078 16.6 0.5 1 23 185 207 185 207 0.98

2 8 0.00016 0.013 16.0 3.3 1 21 213 233 213 237 0.90

3 8 0.0034 0.27 11.8 0.1 1 19 423 441 423 444 0.93

4 8 1.6e-06 0.00013 22.2 2.0 1 23 968 990 968 990 0.99

5 8 6.4e-06 0.0005 20.4 3.2 1 23 996 1020 996 1020 0.92

6 8 1.6e-05 0.0013 19.1 3.6 2 23 1470 1491 1470 1491 0.98

7 8 0.00047 0.037 14.5 1.2 1 23 1497 1521 1497 1521 0.91

8 8 0.0015 0.12 12.9 2.7 1 23 1542 1566 1542 1566 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	9.9e-05	0.0078	16.6	0.5	1	23	185	207	185	207	0.98
2	8	0.00016	0.013	16.0	3.3	1	21	213	233	213	237	0.90
3	8	0.0034	0.27	11.8	0.1	1	19	423	441	423	444	0.93
4	8	1.6e-06	0.00013	22.2	2.0	1	23	968	990	968	990	0.99
5	8	6.4e-06	0.0005	20.4	3.2	1	23	996	1020	996	1020	0.92
6	8	1.6e-05	0.0013	19.1	3.6	2	23	1470	1491	1470	1491	0.98
7	8	0.00047	0.037	14.5	1.2	1	23	1497	1521	1497	1521	0.91
8	8	0.0015	0.12	12.9	2.7	1	23	1542	1566	1542	1566	0.92

Sequence Information

Coding Sequence: ATGGAAAATGCAACATCTACAACAACGACAACTACAAAGCATTATAAGAGCACAGCCAAACAATATAAAACACAAAAAAAATTTAAACGTTTGGCCAGTTCAACTGAAGCAGAAAGTGCCAGCAGTACAACCAGCAATAGCAGTAATCAAAGTACCGGTGCTGGTAGTGGTGGTGTTGCAAGTGGCCCTGGTGGCATCTGTGATGCCATGCGCACCACAAGTCTATCTTCAAATAGCTCACTCTCACCCCAGCCAATAATTGTGAATGGAGGGCAAGCCGCAGCAGTAACATTGAGTGAATTCAGTGCCAATCATCATCAGCATCATGAGGATATGATGAGTAATAATAATATGATTAGCGGTAAAAGTGCTGGCATTTTTAGTGCGAATCATCCACCAAGGACACGTACACCGCTTAGTCAAAGTAATGGCACCACTGGCTTAGGATTAACACCAGCAACATTTGCGCAACATCAACAACAGACGCAACCAACAGCACCGCCAGCAACGGCAACACCATCAGTGCCAACAACTGGCGAAAAGCCTGGCCGCTACACTTGTCCATATTGCAATTTGATTTGTGCCAAACCATCAGTACTCCAAAAGCATATACGTGCCCATACCAATGAGCGTCCATATCCCTGTAATACCTGCGGCATTGCCTTCAAGACCAAAAGCAATCTCTATAAGCATTGTCGCTCCCGATCGCATGCGGCTCGTGCCAGGGGTATAGAAGTCCCAGTTGATGCAGATGATGGTCTATCCGATCAGGATGTAGACAATGAGTTAAGCAACAGTAGCTCCGAATTGCCTAGTCGCTCTGGTTCACCGTATGAAGAGCTGAATATAACATCATCGCCCTCGCCCTCACCATCTACATTGTCGGCTGCCAAAAGTGCCTATTTGCAGCAGCAACAGCATATGCAACAATTGCCATTGGGCTCACCGGCAGCTGGTACATTGCCACCGTTACAGGATAATCTATTGCATACATCAACGGCCAATACATCAGCCCAGCAACGTCATTCAATAGATTATAAGCCATATAAACCAAAATTTCATAATGCCATTCCCCTGGCAGCACCTGTCAACTCCTTGCCATCAGCTAATCGAAGTACATTTGCCAGTGCCAGCGGTGGCATGCAAGTGAATGTGGAAAAGGTGCAAGAGCATATATCGAAATTGATATCACAGAATGAGGCCATAAATCTTTTGCTCAATGCACGCGGTTTGGCTGTGCCCATTGGTGAGGGCGATGATGCTGTCTATTCGTGTCCCATTTGCACAAATGAATTCCGCAGTGCGGATGAATTGAAATTGCATAATAGTACCTATTGTCAGGATGCCAGTTCAAGTGCACCCATGAGTCCGGCTTCATCGCCGAGTACAAAATACTTTCGTTCCAATTCGATTACGCTGAGTTTGGCAGAGGTTAAGTCACATATGGCCAATTCGAAGAATCCTTTATCATTGGCTAAATTGGCATGTGCCTCAAGACAGGGCTCCCAAGATGCTCAAGTCGTTATAACTAAAATGCATGAGGATCGTCAATTTGAAAATGATGCTAAAAGACCCAAAATGAGTAATGATTCATTTAATTTTCCCACCTTAATGTTTGCCAGCGTTAACAGCAATCACAACCACAACAACAACAATTTGGAACCGCAATCTAGTAAAGAGGAACGTCTTAGACGTTTCACCTCTTCAGGTGGCTCAATGATTCCACTCTCCGAGTGTCCGGAATTGGATAAAAGTCCCAAAATCATACGTACACCACTTTTATCCGGTGGCAGTTTTCAAGAAATGTCACCCAGCAAGGAACGTAAATTGCTGACGACAACAACGAGTGCTCAACATTTTCAATTTCCACCAATTAATTCCATAACCGCCTTCAATCCATTGACATTGCCACCCATGACAATAGAGAAACCATCATCATCATCATCATCATCAGCTGGTATACCTTATGTGCCCGGAATACCAGGACCAAGTAGCCTAACGCCACAAATGAATTTATTGCCACCGCCGCCACAACAATTGCAATTGCCATTGGCAGGACAACGACAACGTAGTCCAAATCGTAAGCAACCGAGTCCATTGCTCGGCGGTGCTCTCTCCCCGTTTGGTGGAGTGCAAAATGTGCCCAAAACTCCCAATGGCAATACAGAAGAGATGCAGCCTCAAAGTTTACCAGCCAAGACGAAGTTTTTACGTCCCACCAGCTTGCCACTGAAACCGGGAACATTCACACCAAAACGTCATCATGGCATCACACCAACAGCCAATACATTGCCTCTGATATCACCAGAAACGCCACGGCCATCGAAATCATGTGTTCAACTCTATTTAAATGGTCATGCATATACGTATTTGGGCTTGAAGTGCAGTACGAAAATGTTTTACTGTACAGTAAACTGTCCGCAACCTTCGTATGTGGCTGATATGCATAAGCTGTCCATGTATAGTGTTTGGCAAGTCTGTGAGGAGAATCAACCGCATCCATTGGGCTTTAAATTGAAGCAAGTGATGTCTCTCTACGATTCGCGTCAAAAGATGTTGGGTAATGGTTCCTCAACCACCTCAATGGCCGGAAAATTGAGCTATACCCAGGTCTATTCACAGCAAACTGTTAGCACAGTATCAACATCAAAGCCGAGTAGTTCGTTTTATCAGCATCCATTGAAACAATTACCGGCACCACCTTCGATAACAAGCATCGCCACAAGCACATCTCCCGGAACCACATCCACAGTGGGTGCTTTGAGTGAGGCCAATGTGGCGGCCAAGGCGGCAAGTGAAGATGCAGCAACGGCCAAGAAATTGCAAGAGGGACAACAATTGGTTGGTGGCTATGAATCGCATGAGGATTACACTTATATACGGGGACGTGGACGCGGACGTTATGTCTGCTCGGAATGCGGCATACGGTGCAAGAAGCCATCGATGCTTAAAAAGCATATTCGTACTCACACAGATGTCCGTCCATTTACCTGCAGTTTGTGCAATTTTAGCTTCAAGACCAAGGGAAATCTCACCAAGCATATGCAATCGAAAACTCATTTCAAGAAATGCAGCGGCGGTGAATTTCTGGATGCCGATGTGGACTTCGATCAGCAATCTTCCACTTCGGCTGGCGGAAGAACTTCGTCCATGGCTGGTGAATCGGACTCCGATGATTTCAGTGACAATGAATCGGAAAGTAGTGATACTGATGAATCCAAGTCACGTTTGAAAGAGCATGAGGCGGCACGGTGTCTGCTCTCGCTATCCATGACTCCACCAATACCACAAAGTGTCTCACCATATTCACAAACTCAAGATGCTTCACAACCTGCACCAGCGGCGAGTCCAGCTAACAGCATTGGCTCGACAGGATCACAACCGAAACGTTTGGTTTGTTCATTTACATCGCCAAAGCCGCCATTTGATTATCAGAAACAGGAACAGTATTATTCCAATCCAGAGGAATCCAAACCGAAAGGAAGTTTGGCCAGCGATGAGAGTGCTCCAATGGATTTGACCAAGCCACGGCCAAGCTCTAGCTCCAACTCCAACGCTATCAATAATTCCAATCATCATTCGAGCAGCAATCATCTTCATCATCATCAGTCTATGCAAGATTTGCCCAAATCTCAGGCCCAACAGATAAGGGAAGTGATTTTCGGGACATCGGCCAATGAGAGCGGTTTCATGAAGACTTTAATATCGGTTTCCGATAAAGTGCGTATATCAGCAGAAATGGAAGAGCAAGTGAAGCTGAATGCAGCCGAAAATGAAGGTGAAGATTTGCTATTTCAAACGTATATCAAGGAGCAGGCTCTGCAGCACGCCAAAATGAAGCAGAGTCAGTTTAGTCGCAATTATCAAATAAATGTGACAACTACCAGTACTAGTTCATGTGGCAGTCGTCCTGTGATGAGTATCAAAGAATTGCCCACCATAGAAGTTAATGAGGTGAAGACACCAGATGAGACACCTCCAGCAGCACCACCCTCAAAAGCAGTATCTCCTCCTCCTACTTCTGTTCCTATTCCCGCCATAGAAGCCAATGAAAATCAAGAAATGGAATCGACAGTTGAGAAAAAGATAAACGATGAACAGCCTGCAACAACAACAACAACAGCAACAACAACAACTGCGGATGTATCCCCACATAATGCCAATTTACCAGCAGCTGTGCAACAACCAGATGCAACAGATTTCAAAGGTGTACTCACTAGTGGCTCTACCACGGCTACATCCACTTCCAGTGGACCACCGACGCCTCTCACACGTCCTGTGATCCGCGGTGAGGATAAATTCAAGCCAGCTGATTTACCTGTTAGCAGTACCGTGAGCAATGCCTCTGCATTTCCTCAACGTGTGGTGGCCCCTCCACCGCCCCCGATTGCCAGCGATGCTCGCCCTACCTGCAACATTTGCCAGAAAACTTTTCAACGCCAGCATCAACTCACTCTCCATATGAATATCCATTATATGGAACGCAAATTTAAGTGTGAACCCTGCAGCATTTCGTTTCGCACTCAGGGTCATCTCCAGAAACACGAACGTTCCGAGGCCCATAAGAATAAAGTGATGATGACATCGACTTTTGGTGTCCCAACCACCTCGAATCCGCGACCCTTTGAGTGCACCGACTGTAAGATAGCCTTTCGCATTCATGGCCATTTGGCCAAGCACTTGAGATCAAAGACTCATGTCCAGAAATTGGAATGCCTACAGAAATTGCCCTTCGGCACCTATGCAGAGATCGAACGGGCTGGCATTAGTCTAACCGAAATCGATACAAGCGATTGCGAGAATTCGTTAATCTCATTAAAATTGCTGGCCCAAAAGCTACTCGAAAAGGATCCGAATAAGCTAAGTGGCTACACATCCCCCTCGGGTATGGCACAGGATAGTGCCTCTGAAGATGGTTTCAGTGCGGCAAATAGTGCTGCTGCCTCGGCCATAGCCTCATTGGATAATGATAGTGCCGGCAATACACCGCAGCGAGCAAGTTCCATGTCCGAGGATGAGACACTGACCACGCAGCAGAGTTTGAAACGCCGTCTGCCCGCCACTAGTTTCAGCAGCAACGGCGAAGAGAGTGACAATCCTCAGGAGAATGGTGGTGGCAATGAAAAGCGTGCAAGATTACAACAAAACCAACAACACAACCACTCTTTACTCTAA
Protein Sequence: MENATSTTTTTTKHYKSTAKQYKTQKKFKRLASSTEAESASSTTSNSSNQSTGAGSGGVASGPGGICDAMRTTSLSSNSSLSPQPIIVNGGQAAAVTLSEFSANHHQHHEDMMSNNNMISGKSAGIFSANHPPRTRTPLSQSNGTTGLGLTPATFAQHQQQTQPTAPPATATPSVPTTGEKPGRYTCPYCNLICAKPSVLQKHIRAHTNERPYPCNTCGIAFKTKSNLYKHCRSRSHAARARGIEVPVDADDGLSDQDVDNELSNSSSELPSRSGSPYEELNITSSPSPSPSTLSAAKSAYLQQQQHMQQLPLGSPAAGTLPPLQDNLLHTSTANTSAQQRHSIDYKPYKPKFHNAIPLAAPVNSLPSANRSTFASASGGMQVNVEKVQEHISKLISQNEAINLLLNARGLAVPIGEGDDAVYSCPICTNEFRSADELKLHNSTYCQDASSSAPMSPASSPSTKYFRSNSITLSLAEVKSHMANSKNPLSLAKLACASRQGSQDAQVVITKMHEDRQFENDAKRPKMSNDSFNFPTLMFASVNSNHNHNNNNLEPQSSKEERLRRFTSSGGSMIPLSECPELDKSPKIIRTPLLSGGSFQEMSPSKERKLLTTTTSAQHFQFPPINSITAFNPLTLPPMTIEKPSSSSSSSAGIPYVPGIPGPSSLTPQMNLLPPPPQQLQLPLAGQRQRSPNRKQPSPLLGGALSPFGGVQNVPKTPNGNTEEMQPQSLPAKTKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVADMHKLSMYSVWQVCEENQPHPLGFKLKQVMSLYDSRQKMLGNGSSTTSMAGKLSYTQVYSQQTVSTVSTSKPSSSFYQHPLKQLPAPPSITSIATSTSPGTTSTVGALSEANVAAKAASEDAATAKKLQEGQQLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSLCNFSFKTKGNLTKHMQSKTHFKKCSGGEFLDADVDFDQQSSTSAGGRTSSMAGESDSDDFSDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYSQTQDASQPAPAASPANSIGSTGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKGSLASDESAPMDLTKPRPSSSSNSNAINNSNHHSSSNHLHHHQSMQDLPKSQAQQIREVIFGTSANESGFMKTLISVSDKVRISAEMEEQVKLNAAENEGEDLLFQTYIKEQALQHAKMKQSQFSRNYQINVTTTSTSSCGSRPVMSIKELPTIEVNEVKTPDETPPAAPPSKAVSPPPTSVPIPAIEANENQEMESTVEKKINDEQPATTTTTATTTTADVSPHNANLPAAVQQPDATDFKGVLTSGSTTATSTSSGPPTPLTRPVIRGEDKFKPADLPVSSTVSNASAFPQRVVAPPPPPIASDARPTCNICQKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTSPSGMAQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLTTQQSLKRRLPATSFSSNGEESDNPQENGGGNEKRARLQQNQQHNHSLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00503446;
90% Identity: -
80% Identity: -