Basic Information

Insect: Drosophila equinoxialis
Gene Symbol: Hivep1
Assembly: GCA_018150345.1
Location: JAECWI010000600.1:10354434-10362113[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00011 0.0086 16.6 0.5 1 23 127 149 127 149 0.98

2 8 0.00017 0.014 15.9 3.3 1 21 155 175 155 179 0.90

3 8 0.0037 0.29 11.7 0.1 1 19 422 440 422 443 0.93

4 8 1.8e-06 0.00014 22.2 2.0 1 23 1043 1065 1043 1065 0.99

5 8 6.9e-06 0.00055 20.3 3.2 1 23 1071 1095 1071 1095 0.92

6 8 1.8e-05 0.0014 19.0 3.6 2 23 1541 1562 1541 1562 0.98

7 8 0.00051 0.041 14.4 1.2 1 23 1568 1592 1568 1592 0.91

8 8 0.0017 0.13 12.8 2.7 1 23 1613 1637 1613 1637 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00011	0.0086	16.6	0.5	1	23	127	149	127	149	0.98
2	8	0.00017	0.014	15.9	3.3	1	21	155	175	155	179	0.90
3	8	0.0037	0.29	11.7	0.1	1	19	422	440	422	443	0.93
4	8	1.8e-06	0.00014	22.2	2.0	1	23	1043	1065	1043	1065	0.99
5	8	6.9e-06	0.00055	20.3	3.2	1	23	1071	1095	1071	1095	0.92
6	8	1.8e-05	0.0014	19.0	3.6	2	23	1541	1562	1541	1562	0.98
7	8	0.00051	0.041	14.4	1.2	1	23	1568	1592	1568	1592	0.91
8	8	0.0017	0.13	12.8	2.7	1	23	1613	1637	1613	1637	0.92

Sequence Information

Coding Sequence: ATGGTTGCCGATGGTGACCATCAACAAACAACAACAACAACAACAGATGTTGGCCATATCAATAGCATTGAATCGGCCGGCACAATTGCCGCCGTCGCTGCTGATTGGACACAAAATTCAAGATATTTGCATAAGAAATTCAAACGTTTGGCCAGTTCAACTGAAGCAGAAAGTGCCAGCAGTACAACCAGCAATAGCAGTAATCAAAGTGCTGGTGGTGCAAGTGGTCCTGGTGGCATCTGTGATGCCATGCGTACCACAAGTTTAACACCGGCAACATTTGCCCAACATCAGCAACAGACACAACCAACAGCAGCTCCAGCTCCAGCTCCAACGGCATCACCATCAGTGCCAACAGCTGGCGAAAAGCCTGGCCGTTACACTTGTCCATATTGCAATTTGATTTGTGCCAAACCATCCGTACTGCAAAAGCATATACGTGCCCATACCAATGAGCGTCCATATCCGTGTAATACCTGCGGCATCGCTTTCAAGACCAAAAGCAATCTCTACAAACATTGTCGCTCCCGATCGCATGCGGCTCGTGCCAGGGGTATAGAAGTCCCAGTCGATGCAGATGATGGTCTATCCGATCAGGATGTAGACAATGAGCTAAGCAACAGTAGCTCTGAATTGCCTAGTCGCTCTGGTTCGCCGTACGAAGAGCTGAATATAACATCGTCGCCCTCGCCCTCACCATCTACATTGTCGGCTGCCAAAAGTGCCTACTTGCAACAGCAGCAGCATATGCAACAATTGCCATTGGGTTCACCGGCAGCTGGTACATTGCCACCATTGCAGGATAATCTATTGCATACATCAACGGCCAATACATCAGCCCAGCAACTTCCCCTGGCAGCACCTGTCAATTCCTTGCCATCAGCTAATCGAAGCACATTTGCCAGTGCCAGCGGTGGCATGCAAGTGAATGTGGAAAAGGTGCAAGAGCATATATCGAAATTGATATCACAGAACGAGGCCATATTGCCAAATGCCAATAACAATCATGTGATGCCCTTGAATTTGTCCAGCAAGGCTAAGCCAAATAATATAGCCCCACCACCCGCACCAGCAGCACCAGCAGCAGCAGCTCAAGTAGCCACAGTTGTTATGCCATCAACGACAACGACTCCACTTGTTGCTCCTGTGGCCAGCACTTCCAAATCGGCAACAACGGCAAATGTCAATCATTCCATTATTAAGAATCTTTTGCTCAATGCACGCGGTTTGGCTGTGCCCATTGGTGAGGGCGATGATGCTGTCTATTCGTGTCCCATTTGCACTAATGAATTCCGCAGTGCGGATGAATTGAAATTGCATAACAGTACCTATTGTCAGGACGCCAGCTCAAGTGCACCCATTAGTCCGGCCTCATCGCCAACTACAAAATACTTTCGTTCCAATTCGATTACGTTGAGTTTGGCAGAGGTTAAGTCACATATGGCCAATTCGAAGAATCCTTTGTCATTGGCTAAATTGGCATGTGCCTCAAGACAGGGCTCCCAAGATGCTCAAGTTGTGATAACTAAAATGCATGAGGATCGTCAATTTGAAAATGATGCCAAAAGACCAAAAATGAGTAATGATTCATTTAATTTTCCCACCTTAATGTTTGCCAGCGGCAGCAGCAGCAGCCACAACAACAACAACAACAACAATAACACCATGGAGCCGCAATCTAGTAAAGAGGAACGCCTAAGACGTTTCACCTCTTCAGGTGGCTCAATGATTCCACTCTCCGAGTGTCCAGAATTGGATAAAAGTCCCAAAATCATACGTACACCACTTTTATCCGGTGGCAGTTTTCAAGAAATGTCACCCAGCAAGGAACGCAAATTGCTGACAACAACAACGAGTGCTCAACATTTTCAATTTCCACCAATTAATTCCATCACCGCCTTCAATCCATTGACATTGCCACCCATGACAATAGAGAAACCATCATCATCCTCATCATCATCATCAGCTGGTATACCCTATGTGCCGGGTATACCAGGACCGAGTAGCCTAACGCCACAAATGAATTTGTTGCCACCGCCGCCACAACAATTGCAATTGCCATTGCCAGGACAACGACAACGTAGTCCAAATCGTAAGCAACCGAGTCCCTTGCTCGGTGGTGCTCTCTCCCCCTTTGGCGGAGTGCAAAATGTGCCCAGTGAGTTTAGCCGACAGCCACCAACACCAGCACAAAGGAATGCTATGCAATGGAATAAGGATGTGGCAGCTAAAAAGGCTCCATTCAATTTTTTAAGAATGGCCGATAATGTAAAGGCTCAACCACTTCAGGAAGTGCGTCATTTCAATTTTGATAATCTGCAGGCAACAACGAGCAACAGCATCAACAAGGAACCCCTTACGCCTCTGCACATAGAGACGCCCAATGGCAATGCAGAGGAGATGCAGCCTCAAGCCTTACCAGCCAAGACGAAATTTTTACGTCCCACCAGTTTGCCACTGAAACCGGGAACATTTACTCCAAAACGTCATCATGGCATCACCCCAACGGCCAATACATTGCCTCTGATATCACCAGAGACGCCACGGCCATCGAAATCATGTGTTCAACTCTATTTAAATGGCCATGCCTATACGTATTTGGGTTTAAAATGCAGTACGAAAATGTTTTACTGCACTGTAAATTGTCCGCAGCCTTCGTATGTGGCTGATATGCATAAGCTGTCCATGTATAGTGTTTGGCAGGTCTGTGAGGAGAATCAACCGCATCCTTTGGGCTTTAAATTGAAGCAAGTGATGTCTCTCTATGATTCGCGTCAAAGGATGTTGGGTAATGGTTGCTCAACCACCTCAATGTGTGGCAAATTGAGCTATACCCAGGTCTATTCACAGCAAACTGTTAGCACAGTATCAACATCAAAGCCGAGTAGTTCGTTTTATCAGCATCCATTGAAACAATTGCCAGCACCACCATCGATAACCAATACGGCAAGCACATCTCCTGCAATCACATCCACAGTGGGTGCTTTGAGTGAGGCTAATGTGGCGGCCAAGGCGGCAAGTGAAGATGCAGCAACGGCCAAGAAATTGCAAGAGGGACAACAATTGGTTGGTGGCTATGAATCGCATGAGGATTACACTTATATACGAGGACGTGGACGCGGACGTTATGTATGCTCGGAATGTGGCATACGCTGCAAGAAGCCATCGATGCTTAAAAAGCATATACGTACTCACACAGATGTGCGTCCATTTACCTGCAGTCTATGCAATTTTAGCTTCAAGACTAAGGGAAATCTTACCAAGCATATGCAATCGAAAACTCATTTCAAGAAATGCAGCGGCGGTGAATTTCTTGATGCCGATGTGGACTTTGATCAGCAATCGTCCACATCGGCTGGTGGACGAACTTCATCAATGGCTGGTGAATCGGATTCCGAGGATTTTACTGACTCAGAAAGTAGTGATACTGATGAATCCAAGTCACGTTTGAAAGAGCATGAGGCGGCCCGGTGTCTGCTCTCGCTATCCATGACTCCACCAATACCACAAAGTGTCTCACCATATTCACAAACTCAAGATGCTTCACAGCCAGCACCAGCAGCGAGTCCAGCTAATAGCATTGGCTCCACAGGATCGCAACCGAAGCGTTTGGTTTGTTCATTCACATCGCCAAAGCCGCCATTTGATTATCAGAAACAGGAACAGTATTATTCCAATCCAGAGGAATCCAAACCGAAGGGAAGTTTGGCCAGCGATGAGAGTGCTCCAATGGACTTGACCAAGCCACGGCCAAGCTCTAGCTCCAACTCCATCAACAATTCCAATCATCAGCCAAGCAGCAATCATCATTATCACCATCATCAGGCTATGCAAGATTTGCCCAAATCTCAGGCCCAACAGATAAGGGAAGTGATTTTCGGGACATCGGCCAATGAGAGTGGTTTCATGAAGACCTTAATATCGGTTTCCGATAAAGTGCGTATATCAGCAGAAATGGAAGAGCAAGTGAAACTGAATGCAGCCGAAAATGAAGGTGAAGATTTGCTATTTCAAACATACATAAAGGAGCAGGCACTGCAGCATGCCAAAATGAAGCAGAGTCAATTTAGTCGTAGTTATCAAATAAATCTGACGACTAGCAGTACGACTAGTTCAAGCAGTAGTCGTCCTGTGATGAGCATCAAAGAATTGCCCACCATAGAGGTTAATGAGGTGAAGACACCAGACGAGAATCCTCCGGCAGCCACACCCACAAGAGCAGTAACTCCTCCTTCTTCTGCTCCCGCCATAGAAGCAATTGAAAGTGAGGAAATGGAAACGCCAGCTGAGGAAAAGAAAATCGATGAACAGCCTGTAACAACAACAACAGCAACAACAGCATCAACAATAACGGATATTCCCCCACATAATGCCAATTTACCAGCAGCTGTCCAACAACCAGATGCCACAGATTTTAAAGGCGTACTCACTAGTAGCTCCTCCACGGTTACATCCACTTCCAGTGGACCATCGACGCCACTCACACGTCCAGTGATCCGGAGTGAGGATAAATTCAAGACTGCTGATTTACCTGTTAGTAGTACGGTGAGCAATGCCTCTGCATTTCCTCAACGTGTGGTGGCTCCACCACCGCCACCCATTTCCAGCGATGCTCGCCCTACCTGCAACATTTGCCAGAAAACTTTCCAACGCCAGCATCAACTCACTCTCCATATGAATATCCATTATATGGAACGCAAATTCAAATGTGAACCCTGCAGCATTTCGTTTCGCACTCAGGGTCATCTCCAGAAACACGAACGTTCCGAGGCCCATAAGAATAAAGTGATGATGACGTCGACTTTTGGCGTGCCAACCACCTCAAATCCGCGACCCTTTGAGTGTACCGACTGTAAGATAGCCTTTCGAATTCACGGCCATTTGGCCAAGCACTTGAGATCAAAGACTCATGTCCAGAAATTGGAATGCCTACAGAAATTGCCATTCGGCACCTATGCAGAGATCGAACGGGCTGGCATCAGTCTAACCGAAATCGATACAAGCGATTGTGAAAATTCGTTAATCTCATTGAAATTGCTGGCCCAAAAGCTACTCGAAAAGGACCCGAATAAGCTAAGTGGTTACACATCCCCCTCGGGTATGGCCCAGGATAGTGCCTCCGAAGATGGTTTCAGTGCGGCTAATAGTGCTGCTGCCTCGGCCATTGCCTCATTGGACAATGATAGTGCTGGCAATACACCGCAGCGAGCTAGTTCCATGTCCGAGGATGAGACAGTGACCACTCAGCAGAGCTTAAAACGTCGTCTGCCCGCCACTAGTTTCAGCAGCAATGGCGAAGAGAGTGACAATCCACAGGAGAATGGTGGTGGTGGCAATGAAAAGCGCCCAAGATCTCAGGACTTGGCTGCAGCCACTGCAGCAGCAAGCAACTGA
Protein Sequence: MVADGDHQQTTTTTTDVGHINSIESAGTIAAVAADWTQNSRYLHKKFKRLASSTEAESASSTTSNSSNQSAGGASGPGGICDAMRTTSLTPATFAQHQQQTQPTAAPAPAPTASPSVPTAGEKPGRYTCPYCNLICAKPSVLQKHIRAHTNERPYPCNTCGIAFKTKSNLYKHCRSRSHAARARGIEVPVDADDGLSDQDVDNELSNSSSELPSRSGSPYEELNITSSPSPSPSTLSAAKSAYLQQQQHMQQLPLGSPAAGTLPPLQDNLLHTSTANTSAQQLPLAAPVNSLPSANRSTFASASGGMQVNVEKVQEHISKLISQNEAILPNANNNHVMPLNLSSKAKPNNIAPPPAPAAPAAAAQVATVVMPSTTTTPLVAPVASTSKSATTANVNHSIIKNLLLNARGLAVPIGEGDDAVYSCPICTNEFRSADELKLHNSTYCQDASSSAPISPASSPTTKYFRSNSITLSLAEVKSHMANSKNPLSLAKLACASRQGSQDAQVVITKMHEDRQFENDAKRPKMSNDSFNFPTLMFASGSSSSHNNNNNNNNTMEPQSSKEERLRRFTSSGGSMIPLSECPELDKSPKIIRTPLLSGGSFQEMSPSKERKLLTTTTSAQHFQFPPINSITAFNPLTLPPMTIEKPSSSSSSSSAGIPYVPGIPGPSSLTPQMNLLPPPPQQLQLPLPGQRQRSPNRKQPSPLLGGALSPFGGVQNVPSEFSRQPPTPAQRNAMQWNKDVAAKKAPFNFLRMADNVKAQPLQEVRHFNFDNLQATTSNSINKEPLTPLHIETPNGNAEEMQPQALPAKTKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVADMHKLSMYSVWQVCEENQPHPLGFKLKQVMSLYDSRQRMLGNGCSTTSMCGKLSYTQVYSQQTVSTVSTSKPSSSFYQHPLKQLPAPPSITNTASTSPAITSTVGALSEANVAAKAASEDAATAKKLQEGQQLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSLCNFSFKTKGNLTKHMQSKTHFKKCSGGEFLDADVDFDQQSSTSAGGRTSSMAGESDSEDFTDSESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYSQTQDASQPAPAASPANSIGSTGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKGSLASDESAPMDLTKPRPSSSSNSINNSNHQPSSNHHYHHHQAMQDLPKSQAQQIREVIFGTSANESGFMKTLISVSDKVRISAEMEEQVKLNAAENEGEDLLFQTYIKEQALQHAKMKQSQFSRSYQINLTTSSTTSSSSSRPVMSIKELPTIEVNEVKTPDENPPAATPTRAVTPPSSAPAIEAIESEEMETPAEEKKIDEQPVTTTTATTASTITDIPPHNANLPAAVQQPDATDFKGVLTSSSSTVTSTSSGPSTPLTRPVIRSEDKFKTADLPVSSTVSNASAFPQRVVAPPPPPISSDARPTCNICQKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTSPSGMAQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETVTTQQSLKRRLPATSFSSNGEESDNPQENGGGGNEKRPRSQDLAAATAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523905;
90% Identity: -
80% Identity: -