Dins018103.1
Basic Information
- Insect
- Drosophila insularis
- Gene Symbol
- -
- Assembly
- GCA_018903935.1
- Location
- JAEIFP010000752.1:1520244-1523504[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 5.5 4.3e+02 1.7 2.5 3 17 61 75 60 76 0.88 2 13 0.0016 0.13 12.8 0.0 1 23 211 236 211 236 0.96 3 13 2.5e-05 0.002 18.5 2.1 1 23 241 264 241 264 0.96 4 13 1.3e-05 0.001 19.4 3.6 1 23 269 291 269 291 0.98 5 13 4.7e-05 0.0037 17.7 4.1 2 23 298 319 297 319 0.97 6 13 0.00041 0.032 14.7 2.4 3 23 331 352 330 352 0.95 7 13 0.0012 0.096 13.2 0.3 1 23 358 381 358 381 0.96 8 13 0.0035 0.27 11.8 1.0 2 23 392 414 391 414 0.96 9 13 0.00021 0.016 15.6 0.9 1 23 442 464 442 464 0.96 10 13 2.4e-05 0.0019 18.6 5.8 1 23 471 493 471 493 0.96 11 13 8.3e-05 0.0065 16.9 0.2 2 23 500 521 500 521 0.97 12 13 0.00031 0.025 15.1 1.4 1 23 528 550 528 550 0.99 13 13 0.00022 0.017 15.6 2.4 1 23 556 579 556 579 0.97
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACCTGTGCGCTTTCTATGTTTGTATGCGATTTTGAAAATGGAAACAATAATTTTTTGGACCTATTCCATCCCACATGTTGGCAGAGCGAAATGGGCCAAATACGCATGGAGTTTCTTAACTGGAATTTAAAGATATTACCAAATGATGGGCTGCCTCAAAAGATTTGCAGCGATTGTTTTACAAAATTTTGTTCGTTATATACATTTCGGTTAACGTGCCAAGAGGCGCAAGTAAAACTCCTGAACATCTATGAGAAAATCGATGCCAGCAGTTTGGATGATCACTCGGAAATGGAACCGGAACCAGACCCGGATACTGAGGAAGTTGATTTGAATCTAAAGAATGAAATTAATGCCACAAATGAAACAGCAACAATGACGGTTTCAACTGAAGCAACACGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCATAGAAATCTATATAGATGCGGCGAATGTGGCAGATGCAACAGAAGAATACTCTTCCGAACTGGTAATAAGCTACGCTTGCAAATTCTGTTTTAAGCCGCAAGAAAGCTTTCAATTGCAACAAATGCTCCTGGAGCACATCAGTAGTGAACATGATCCGGAGCAACCATACAATTGTCCTGAACCCGAATGTGACGAGGCTTTCCAGGATGCCGCATCGCGTACTGTCCACATGAAAAGTGTTCATGTTGATAAACAATTTACTTGTGATGTATGTGGCAAGAAGTATGGGGATCGTCAGAATTTACGACATCATGTTGAGAAATATCATTCGGACACGGATTTTGAATGCAATATGTGTGAGAAGCGATTTTTCACCAAAAAGAGTCTTAAATACCATATGAAATGGCATAATCCTGATCGACAATTAAAGTGTCGTCACTGCGATCGATTGTTTATATCATCTGTACATCTCACTAAACATATGGCCACCCACACCCAAATGGCAAGTGCCCGAAAGAGCGAACATTGTGGACTTTGTGGCAAAGCATTTATACATCTTAAAACTCTACGCTGGCATATCTATAGACAACATGGCGGAGAGAAGCCCTACAAATGTAGCAACTGTACACAAGTCTTTGCATCTTATGCGGAAAAAAGGATACACATGCTGGAGGAACATATGGAGAACCTGACAGCCATTGAAAGAAGCGAGTGTATGCTCTGTAGACAGGTTTTTGGCAAAGAACAGGACTTGGTTCACCATATGAGAAGGGACCACTTAAAAAGCCCATCCGCTCCGGTGATTGTCAATAACAAGCGCGTTTTACAACAAAAACGCGAACGTCAATATTCTGGGCTGTTCCAGTGCGATAGATGCTCACAACGCTTTAATATGAAATCTGCTCTGGAAAGGCATTCAGAGGTTCATTCTGAAAAGGATCGGCCTCATGCCTGTACGCATTGTTCCAAGCGATTCAAACGTGCTCAGGATATGAAGTGGCACATGAAAACGCACGAAAAAGTGAAGCCCAATGTGTGTGATGTGTGTGGCAAGGCGTTTGCCTTGAAGTATGTGCTAACCCAACACAAACGGAGTCATGAAGTTCTCGAAAAGAACTTCAAATGCAATGTATGCGGACGTACGTATCTCTTTGAAAAATCGCTGCGACTTCATCAACGAGTTCACACTGGGATGACCTATTACAACTGTGACCTCTGTCAGGAGCGTTTTGTTACCCATATTAAGTTAAAAACTCATATGCAAAAGATTCATGCCCAAACACAGGCAAAGGATTCCTCATTAGATAATTTAATTAACATTGTGATTTCCTAA
- Protein Sequence
- METCRTCALSMFVCDFENGNNNFLDLFHPTCWQSEMGQIRMEFLNWNLKILPNDGLPQKICSDCFTKFCSLYTFRLTCQEAQVKLLNIYEKIDASSLDDHSEMEPEPDPDTEEVDLNLKNEINATNETATMTVSTEATRXXXXXXXXXXXXXXPIEIYIDAANVADATEEYSSELVISYACKFCFKPQESFQLQQMLLEHISSEHDPEQPYNCPEPECDEAFQDAASRTVHMKSVHVDKQFTCDVCGKKYGDRQNLRHHVEKYHSDTDFECNMCEKRFFTKKSLKYHMKWHNPDRQLKCRHCDRLFISSVHLTKHMATHTQMASARKSEHCGLCGKAFIHLKTLRWHIYRQHGGEKPYKCSNCTQVFASYAEKRIHMLEEHMENLTAIERSECMLCRQVFGKEQDLVHHMRRDHLKSPSAPVIVNNKRVLQQKRERQYSGLFQCDRCSQRFNMKSALERHSEVHSEKDRPHACTHCSKRFKRAQDMKWHMKTHEKVKPNVCDVCGKAFALKYVLTQHKRSHEVLEKNFKCNVCGRTYLFEKSLRLHQRVHTGMTYYNCDLCQERFVTHIKLKTHMQKIHAQTQAKDSSLDNLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00555257;
- 90% Identity
- iTF_00571325;
- 80% Identity
- -