Dins013956.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila insularis
Gene Symbol
IPP
Assembly
GCA_018903935.1
Location
JAEIFP010001084.1:16906927-16910173[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.6e-33 7e-31 106.7 0.1 1 108 86 195 86 197 0.97

Sequence Information

Coding Sequence
ATGCCACCGTTAAAAACTTATTCCATACACCACCACGAATACAATGCAAATTGTCATAATAATGGCAATCCAGCAACAACAAATTCACAGCCCACCAATCATGATGCCGACTTCTATACAGGATTAGGATCAACATCAACAGGAGTTGTCGGTGGAGCAACCAGCTCCTCGTTCTCGTCCTCGTCCAACAATACACAACGCACCAATCGTCCCTCCTATTGCAATGCCCAATACCCTTTCAAAGTTCTCTCCAATTTGAATCAGCTAAGGGAACAATCGCGTTTTTGTGATGTGGAAATAGTTGCTGGTGAAGCCACATTCAACGCCCACAGAGCTGTCTTGAGTGCTGCCAGTGCCTATTTCGAGGCAATGTTTCGACCCGAATTGGGTTTAAATGAATCAAATCCAAATCAAAAATCTGTGGTATTGCATACCATTGATGGCGATATATTGCATATACTCCTTGACTTTATCTACACGGGACGCTGTGAAATAACACAGTCGAATGTCCAAGAACTTTTAGCTGCTGCCGATATGCTTCAACTCAATGAAGTTGTCGATGGTTGCTGTGAGTTTCTTTGCCGCGAGCTGCATGCCACCAATGCCTTGGGTATTTTACGTTTCGCTGAAGCGCACAATTGCGAATCGCTAGCTAAAAGTGCAATCAACTTTGTTCATGCCAATTTTCCAGCGATCACCCTTGAGGATGAATTTCTGGAAACTCCACAATCTTTGCTATCGCAGCTACTTAATTCCGAGATGTTGCGTGTCGACTCCGAATCTCAAGTGTTTCAGGCAGCACTACGTTGGATTAAACACGATGTGACCCAGCGCCGTTGCTATGTTTTTGATATACTTTCCCATGTACGCATGGCTCTTGTTCCAGTGAAGGTCATAGACAAGGCTCTCAAAGATGATTGTCGCGACATGTCGGTGAAGATAGCCCTGCGGTCGATTTGTCGAGATATTGCCTCAAAACGCGGCCAGCTTGTGCCATTGCGGGTTTGTCCTCGTCAACTGGCCAAGAAAAACATTTACATTATTGGTGGATCACATCGCGATACGCCACGAACATGGAATTCAGCTGATTGCATATTTGAGACAGTGGCCAAATTCGATATATTTCGACGAGAATGGACTGAAACGGCCCCTATGGAGGTGGGACGTATACTGCCCGGCGTATCGGCGCTTAATGGAAAGATCTATGTAGTGGGTGGAGAGCGGGGATCTCAGATTCTGGCCAATGGAGAAGTGTATGATCCTCAGAACGATGTGTGGCAACCCATTGCACCAATGATTGTGCCACGCTGCGAATTTGGACTATGCACCATGGGTGGAAATCTGTTTGCGGTTGGAGGCTGGATCGGTGATGACATTGGTGGGACCATGGAATGTTACGATCCGGAAAAGGATCTGTGGAAACTAATCGGCAGTATGCCACAGCCTCGCTTCAGCATGGGTGTGGTCAGTTTTGAGGGTCTGATCTATATTGTAGGTGGATGCACCACAACCACAAGACATTTGCCAGACTTGATAAGCTACAATCCGGTTACCAAAGAATGGACACAATTAGCCCGCATGCAAACAGCTCGTTGTCAAATGGGCGTGGCCGTCCTAGATCGCTATTTATATGTTGTGGGCGGAAGCAGCATCACCCAGGATATTTTAAGCTCTGTGGAGCGTTATAGTTTCGACGAGGATAAATGGTCAACGGTTTGCGCTTTAAATGTACCCAGAGCCATTCCCGCAGTGGCTGCAGCCGATGGTTTGCTATACGTGGCAGGAGGTGATCAGCCATGTGAAGTGAACTTTTATCGTGCTCAAGTCACAATAAGCGCTGTCGAATGCTATGATCCTCTATCAGACACCTGGAAGAATTGTCCCGACTTGCCAGTAAGCCGTTCGGAGGCCGGTGCAGTCGTTGTCTAA
Protein Sequence
MPPLKTYSIHHHEYNANCHNNGNPATTNSQPTNHDADFYTGLGSTSTGVVGGATSSSFSSSSNNTQRTNRPSYCNAQYPFKVLSNLNQLREQSRFCDVEIVAGEATFNAHRAVLSAASAYFEAMFRPELGLNESNPNQKSVVLHTIDGDILHILLDFIYTGRCEITQSNVQELLAAADMLQLNEVVDGCCEFLCRELHATNALGILRFAEAHNCESLAKSAINFVHANFPAITLEDEFLETPQSLLSQLLNSEMLRVDSESQVFQAALRWIKHDVTQRRCYVFDILSHVRMALVPVKVIDKALKDDCRDMSVKIALRSICRDIASKRGQLVPLRVCPRQLAKKNIYIIGGSHRDTPRTWNSADCIFETVAKFDIFRREWTETAPMEVGRILPGVSALNGKIYVVGGERGSQILANGEVYDPQNDVWQPIAPMIVPRCEFGLCTMGGNLFAVGGWIGDDIGGTMECYDPEKDLWKLIGSMPQPRFSMGVVSFEGLIYIVGGCTTTTRHLPDLISYNPVTKEWTQLARMQTARCQMGVAVLDRYLYVVGGSSITQDILSSVERYSFDEDKWSTVCALNVPRAIPAVAAADGLLYVAGGDQPCEVNFYRAQVTISAVECYDPLSDTWKNCPDLPVSRSEAGAVVV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00804457;
90% Identity
iTF_00612135; iTF_00618472; iTF_00571220; iTF_00503327; iTF_00483042; iTF_00536835; iTF_00918212; iTF_00914571; iTF_00916301; iTF_00915407; iTF_00919123; iTF_00917278; iTF_00573382; iTF_00492296; iTF_00613569; iTF_00527363; iTF_00533155; iTF_00593895; iTF_00612874; iTF_00541135; iTF_00617711; iTF_00594609; iTF_00491572; iTF_00485205; iTF_00488725; iTF_00571959; iTF_00489433; iTF_00524474; iTF_00478076; iTF_00490141; iTF_00561821; iTF_00609227; iTF_00832235; iTF_00555148; iTF_01549633; iTF_00563234; iTF_00575650; iTF_00599650; iTF_00531012; iTF_00555908; iTF_00616964; iTF_01550340; iTF_00528869; iTF_00473126; iTF_00550950; iTF_01552518; iTF_00478791; iTF_00516327; iTF_00523015; iTF_00537576; iTF_00533865; iTF_00601865; iTF_00549610; iTF_00588906; iTF_00483755; iTF_00519979; iTF_00554443; iTF_00561099; iTF_01326475; iTF_00475276; iTF_00544556; iTF_00586028; iTF_00598220; iTF_00582317; iTF_01554029; iTF_00476686; iTF_00540430; iTF_00567598; iTF_00569038; iTF_00512783; iTF_00534640; iTF_01554768; iTF_01559824; iTF_00493713; iTF_00526641; iTF_00585265; iTF_01553297; iTF_00495922; iTF_00479539; iTF_00501107; iTF_01551795; iTF_00532436; iTF_01555476; iTF_00572661; iTF_00470934; iTF_00506934; iTF_00509878; iTF_00591030; iTF_00490839; iTF_01551064; iTF_00502585; iTF_01548921; iTF_01557625; iTF_00519226; iTF_00547418; iTF_00600378; iTF_00608506; iTF_01558362; iTF_00545307; iTF_00557980; iTF_00610716; iTF_00506173; iTF_00541821; iTF_00559549; iTF_00901565; iTF_01559101; iTF_00546718; iTF_00604159; iTF_00551648; iTF_00583744; iTF_00802912; iTF_01556896; iTF_00504750; iTF_00486625; iTF_00581601; iTF_00512067; iTF_00548131; iTF_00592451; iTF_00602659; iTF_00605637; iTF_00539719; iTF_00515656; iTF_00619208; iTF_00607849; iTF_00607850; iTF_00591758; iTF_00578607; iTF_00596719; iTF_00604912; iTF_00494450; iTF_00588210; iTF_00505466; iTF_00529626; iTF_00474558; iTF_00487360; iTF_00336815; iTF_00525936; iTF_00510610; iTF_00507673; iTF_01319824; iTF_00577844; iTF_00530327; iTF_00590297; iTF_00339226; iTF_00568315; iTF_00337598; iTF_00335973;
80% Identity
-