Dinn000965.1
Basic Information
- Insect
- Drosophila innubila
- Gene Symbol
- Aef1
- Assembly
- GCA_004354385.1
- Location
- NW:7938670-7943614[-]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.00091 6 6.7 0.1 20 48 192 220 183 224 0.87 2 4 2.8e-05 0.18 11.5 0.0 21 52 221 252 219 254 0.89 3 4 0.063 4.2e+02 0.8 0.1 21 45 249 273 247 276 0.88 4 4 8.5e-05 0.56 9.9 0.1 21 47 277 303 273 310 0.88
Sequence Information
- Coding Sequence
- ATGATGCATATCAAGAGCCTGCCACACGCACATCAGGCCGCTGCGGCAATGAGCAATTGTGACATTGTCATTGTTGCCGCACAACCGCAAACAACCAgcgccaacaataacaacaatgataCGGTCACACAGGCAAGCCATGCCAGCCATGTGGCAGCTGTGGCGCACgcacagcatcagcagcagcaacaacaacaacagcaacagcagcaacaacaacagcagcagcagcaacaacagcagcagcagcaacacaatcaacagcaacaacaacagccgccCGCGCCCACAGAAATCGCCCTACCCTTTAACATGCATTTGAGTGGAATTTCACCGGAGGCACACAGTGCTGCCCAAGCGGCAGCAATGGCAGCTGCGCAGGCCGCGGCAGCGCAAGCAGCCGCTGCGGATCAACAGCAGCCTTCGTCAGCTCCAGCACAGCTGGCGCATCTGGTGGCCAATGCAACGCATAGTCCGGTTGAATCGCATTACGTGAGCAATGGACACTCTGGTGGTGGTAATAATGATCATTCGGGTGAGGGCAACGGATCGAGCAGCAGCGGCGGAGGGCGGGAGTCGGAGAAACCGTTCCATTGCACTGTGTGCGATAGACGCTTCCGTCAGTTGAGCACACTGACCAACCATGTGAAGATCCATACCGGAGAGAAGCCCTACAAATGCAACGTTTGTGATAAGACGTTCCGTCAATCGTCCACACTGACGAATCATCTGAAAATTCATACTGGCGAAAAGCCATACAATTGCAACTATTGCCCCAAGCATTTCCGTCAGCTGAGCACTTTGGCCAATCATGTGAAGATTCATACGGGTGAAAAGCCGTTCGAGTGCGTCATATGCAAGAAACAATTCCGGCAATCCAGCACGCTCAACAATCACATAAAGATCCATGTCATGGACAAGGTCTACGTTCCTGTCAAGATCAAAACCGAGGAGGACGAGGGGTGACTAGGACGCATGGCGTTGGCGCAGCATCATCAtctccagcaacagcaacatcatcaacagtCGTCAACGCCatctcagcaacaacagcaacaacaacagcaacagcagcagcaacaacagcaccacaTCGAACATCAACGGGGAGTTACAATTACAACGCTGCCATCCACAACGACAGTGgcacaacatcagcaacagcagcagcagcaacaatcgcATCTGCAGCCTACGCATGGCAATGGCACCTCGCCGCATCATCATCCGCATTTCAATGTGGCCGCTTTGGGTGATTTGTCCAGTGCAATGCAATTGGGCGCTGTAACAGCCGATGGTAATTTTGTGACCATGGGCGGTGTTGTCGTTGGACGCATACAACATCCGAGAAgtgagcaactgcagcagctggGCGTCATCAAAATGGAGTCGCCAACGAATGGCATTGCAGCCGCTGCTCAACGCGATGGATGA
- Protein Sequence
- MMHIKSLPHAHQAAAAMSNCDIVIVAAQPQTTSANNNNNDTVTQASHASHVAAVAHAQHQQQQQQQQQQQQQQQQQQQQQQQQQHNQQQQQQPPAPTEIALPFNMHLSGISPEAHSAAQAAAMAAAQAAAAQAAAADQQQPSSAPAQLAHLVANATHSPVESHYVSNGHSGGGNNDHSGEGNGSSSSGGGRESEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG*LGRMALAQHHHLQQQQHHQQSSTPSQQQQQQQQQQQQQQQHHIEHQRGVTITTLPSTTTVAQHQQQQQQQQSHLQPTHGNGTSPHHHPHFNVAALGDLSSAMQLGAVTADGNFVTMGGVVVGRIQHPRSEQLQQLGVIKMESPTNGIAAAAQRDG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00523190;
- 90% Identity
- iTF_00523190;
- 80% Identity
- iTF_00523190;