Basic Information

Insect: Drosophila innubila
Gene Symbol: zfh1
Assembly: GCA_004354385.1
Location: NW:21185074-21216151[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0053 0.3 11.2 1.8 2 23 76 98 75 98 0.95

2 9 0.00084 0.047 13.7 0.1 1 23 284 306 284 306 0.97

3 9 7.8e-05 0.0044 17.0 2.0 3 23 321 341 319 341 0.97

4 9 7.4e-05 0.0042 17.1 4.9 1 23 350 372 350 372 0.98

5 9 0.00021 0.012 15.6 1.4 3 21 380 398 378 399 0.94

6 9 0.0068 0.38 10.9 0.7 2 21 649 668 648 669 0.92

7 9 1.3e-05 0.00074 19.4 0.5 1 23 1036 1058 1036 1058 0.94

8 9 4.9e-05 0.0028 17.6 7.4 1 23 1064 1086 1064 1086 0.98

9 9 0.0025 0.14 12.3 4.3 1 21 1092 1112 1092 1113 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0053	0.3	11.2	1.8	2	23	76	98	75	98	0.95
2	9	0.00084	0.047	13.7	0.1	1	23	284	306	284	306	0.97
3	9	7.8e-05	0.0044	17.0	2.0	3	23	321	341	319	341	0.97
4	9	7.4e-05	0.0042	17.1	4.9	1	23	350	372	350	372	0.98
5	9	0.00021	0.012	15.6	1.4	3	21	380	398	378	399	0.94
6	9	0.0068	0.38	10.9	0.7	2	21	649	668	648	669	0.92
7	9	1.3e-05	0.00074	19.4	0.5	1	23	1036	1058	1036	1058	0.94
8	9	4.9e-05	0.0028	17.6	7.4	1	23	1064	1086	1064	1086	0.98
9	9	0.0025	0.14	12.3	4.3	1	21	1092	1112	1092	1113	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTCCCTCCTTGGCCTCCAGTTTGCATCATCATCAAACACACAGCAAGCCCAGCAATGTGGCTGCAAGTGAGGAGCTTGCCACACATGCGGCAAGTGCCACAGCGAGTGCGGCAGATGACTTTTTGGTCAAATGCACGCAATGCCACAAGCGATTCAATGAGTTTCAGTCCCTCAGCGAGCATATTGCCAGTGAACATCCGCATGACAAGCTCAATTATGAGCCACATCgtgctgttgtcgctgtgcAGCCGGAAAGCGACGCGGAGGAAGATGAGCAAAGCAATTTGAGCAGCAACAGTCGACGCTATGCCAAATCCCCatccaacaataacaacaacgagacAGCCaagaatcaaaataataataacaacaacaacaacagcaatcacaGAAGCCAACACTCGCCCATGTGCTCACCTGTTGCCCAAGCACCGCCCAGCGATCTGTTTGCCCACCTGCCGCATCCGCCGCCGCAGCTGCCCGCCCATTTGCACGCCCAGTTTATGGCCGCCGCCGCCTTGGCCATGCAATCGGCACGCTCCGCCAGCTCACCCAGccaacagcagttgcagcagccGCCACAGCAGTTgccacatcagcaacatcagcagtcACAACAACAGTTACTGCTGCCACCGCCACAGcccggcagcaacagcagcgttGGCAGCAATTCCGCCTATGATCTGGATTTAAGTGCACCACGTTCCACCTCCAGTCCTGGCTCCGCAGCCGGCGAACTCGCTTCATCCTTTCCCTGCATGCAATGCACGGCGGCATTTGCCACACGCGAGCAACTCGAGCAGCATCAGTTGTTGCACTCACCCACGGGACAGCAGACAACACACTCCGTGCCACAGATCTGCAAAAAATGCCACAAGGCGTTTGCCAATGTTTATCGCCTGCAGCGTCACATGATCAGTCACGATGAGTCGACGGCGTTGCGTAAGTTCAAGTGTGCACTGTGCGAAAAGGCGTTCAAGTTTAAGCATCACCTCAAGGAGCACGTGCGCATCCATTCGGGAGAGAAACCGTTTGGGTGCGACAAGTGCGGCAAGAGATTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACATCCAAGAAGTGCATCAGCATGGGTTTAAAgcagaccaacaacaacagcaatcacaacaacaacaacaatcgacaGATGCTCAAGACTTTGGATAAAAATGTtgatcaacaacaacagcagcagcaacaacagcaacaacaaatgtctGGCAAGCGTGTCTCCAAGTTGCCAGAGTCGAATCCTCTGCTGCCCCATCCCATGAACTACTTTGCTGGCGAGGCACAGGTGCCGCAGTTGCCATCGGCTGCAGCGAATGCAGCTGCTCCCTTTTATTCCAATTATAATGCCATGAATGCGGCGCTGTTGGCATTTCCCTTTGCGTTCGATCCGCGTCTGGGTCCCTATAGCATTCAGCGATTGCTGGAGCTGACAGCTGCcggacagcagcagcaacaacagcagcagcaacagcagctggaggagcagcagcaacaactggaggagcaacaacaacatgagctGCAGGCTCCTCTTTATGAGCCCATCAAAGATGAGGATGAGACGCCCGATGAGCCAAAGCTGGTCATGGATCTGGAGGAGTCGGAGACCAAGCCAGCCACGCCAGAGTTGCCGCCAGCTGCAGTCAATGCGAATATCCTTTCGCCCAAACAGGAGCAGAGTCGAGAGCCAACGCCAGCGCCGGAAATGACAGCAGATTCACCCAAACCAATTAAGCAGGAGCTGGAGCAGCGGATagaggagcaggagcaagagcaagagcaGGAGGAGTTGGTAACATCACAGGACTTGCGCTGCAGTCGCTGCTCCAAGCAGTTCAATCATCCCACAGAGCTGGTGCAGCATGAGAAAGTGCTCTGCGGACTCATCAAAGAGGAGCTGGAGCAACactaccagcaacaacagcaacaacaacagcagcagcaacaacagcagcaatccTTTGTCAGCGATGCAGATGAAGATGAGGAGGATGgcgagggggagggggaggagCTGGAACCACGACAGGATTACAACGCTGgcggcagcagcgacagcggcgaGCGCAAAGTCCGCGTACGCACCGCAATCAAcgaggagcagcaacagcagctgaagcaACATTATGCCCACAATGCGCGTCCATCGCGTGATGAGTTCCGGCTGATTGCCGCCCGTCTCCAGCTGGATGCACGTGTCGTCCAGGTCTGGTTTCAGAACAATCGCTCGCGGGAACGCAAAATGCAGAGCTATGTGAGCAGCAATGAAGCAACAAGTGTCCCGGCAATgacaccacaacaacaacaacaacagccacaacaccaacaacaaccacgtGCAGGCGAGGATCAGCCGCTGGATTTGTCCTTGAAACGGGATGCATCGCCGCTGTATGGCGTGGCGCCACAGCAGACGACACTGAGTCAGCCGCCCGTTGATTTCGCCGACAACATGGCCATCAATCTGAGCCGCAAGTTGTCCAGCTCGGCATCGATGTCGCCGGCTTCGTTGTCGCCCTGCTCGGGTGGTGCCTCGACGTTGCAACAAacggcggcagcggcggcggcagctgctgcGGCCGCACTCTACTTTGCCCCACCCTCGCCGCCCAGCATGCATCATGAGGCTGTGCCTCCAATGCAGCCACACAGCGCCGCCGGGCCAAGGGGTCAACCGTTTCCCGGACTGCCGCCGTACATGATGCAACGCCTGCCCATGGAGGCGCTCTTCTCGATGCGTCCCGGCGGTGATTATGCGCCCAATCCACTAATGAACAGTATTAAGCTGCCCGATTACCGTGGCACCAGCCTGAGTCCCGGTGGATCCGAGAAGCGTTCCTGGCGCGACGACGATTCGCGCATCTCGCACGAGGATGATTACGTGATGGCCGGAGCCGGCGGATTGTTGCCCCCGAAACCAAAGCGGGCCAAGGCCGAGACCCATGGACATGCGGGTGATCCCGACCTACCCTTCGTGTGCGATCAGTGCGACAAGGCGTTCGCCAAGCAGAGTTCCCTGGCACGACACAAATACGAGCATTCCGGTCAACGACCTTATCAATGCATGGATTGCCCCAAGGCCTTCAAGCACAAACATCATTTGACGGAGCACAAGCGTTTGCATTCCGGCGAGAAGCCATTTCAGTGTTCCAAGTGCTTGAAACGATTCTCGCACTCGGGCAGCTACAGTCAGCACATGAACCATCGGTACTCCTATTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIQQSMPSSTAFSMQFPSLASSLHHHQTHSKPSNVAASEELATHAASATASAADDFLVKCTQCHKRFNEFQSLSEHIASEHPHDKLNYEPHRAVVAVQPESDAEEDEQSNLSSNSRRYAKSPSNNNNNETAKNQNNNNNNNNSNHRSQHSPMCSPVAQAPPSDLFAHLPHPPPQLPAHLHAQFMAAAALAMQSARSASSPSQQQLQQPPQQLPHQQHQQSQQQLLLPPPQPGSNSSVGSNSAYDLDLSAPRSTSSPGSAAGELASSFPCMQCTAAFATREQLEQHQLLHSPTGQQTTHSVPQICKKCHKAFANVYRLQRHMISHDESTALRKFKCALCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCISMGLKQTNNNSNHNNNNNRQMLKTLDKNVDQQQQQQQQQQQQMSGKRVSKLPESNPLLPHPMNYFAGEAQVPQLPSAAANAAAPFYSNYNAMNAALLAFPFAFDPRLGPYSIQRLLELTAAGQQQQQQQQQQQLEEQQQQLEEQQQHELQAPLYEPIKDEDETPDEPKLVMDLEESETKPATPELPPAAVNANILSPKQEQSREPTPAPEMTADSPKPIKQELEQRIEEQEQEQEQEELVTSQDLRCSRCSKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQQQQQQQQSFVSDADEDEEDGEGEGEELEPRQDYNAGGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDARVVQVWFQNNRSRERKMQSYVSSNEATSVPAMTPQQQQQQPQHQQQPRAGEDQPLDLSLKRDASPLYGVAPQQTTLSQPPVDFADNMAINLSRKLSSSASMSPASLSPCSGGASTLQQTAAAAAAAAAAALYFAPPSPPSMHHEAVPPMQPHSAAGPRGQPFPGLPPYMMQRLPMEALFSMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVMAGAGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537703;
90% Identity: iTF_00522861; iTF_00506759; iTF_00507110;
80% Identity: iTF_00522861;