Basic Information

Insect: Drosophila innubila
Gene Symbol: -
Assembly: GCA_004354385.1
Location: NW:14162994-14168340[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6.4 3.6e+02 1.5 9.7 2 23 333 355 332 355 0.96

2 16 0.77 43 4.4 0.0 1 23 362 387 362 387 0.91

3 16 0.017 0.94 9.7 1.8 2 23 398 419 398 419 0.93

4 16 5.2 2.9e+02 1.8 3.0 2 17 430 445 429 456 0.75

5 16 0.0029 0.16 12.1 0.3 3 23 489 509 487 509 0.96

6 16 0.019 1.1 9.5 1.3 1 23 517 540 517 540 0.95

7 16 0.00025 0.014 15.4 2.0 2 23 545 566 544 566 0.97

8 16 0.00027 0.015 15.3 0.4 1 22 614 635 614 638 0.91

9 16 0.013 0.75 10.0 1.3 1 23 683 708 683 708 0.96

10 16 0.011 0.6 10.3 1.4 2 23 724 746 723 746 0.93

11 16 0.0038 0.21 11.7 0.2 3 23 753 774 751 774 0.92

12 16 0.025 1.4 9.1 0.5 2 23 778 800 777 800 0.96

13 16 7.1e-05 0.004 17.1 1.5 1 23 806 829 806 829 0.96

14 16 0.027 1.5 9.0 0.5 1 23 833 856 833 856 0.93

15 16 1.2e-05 0.00069 19.5 1.6 1 23 862 885 862 885 0.97

16 16 0.00011 0.0063 16.5 0.2 5 23 898 917 890 917 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6.4	3.6e+02	1.5	9.7	2	23	333	355	332	355	0.96
2	16	0.77	43	4.4	0.0	1	23	362	387	362	387	0.91
3	16	0.017	0.94	9.7	1.8	2	23	398	419	398	419	0.93
4	16	5.2	2.9e+02	1.8	3.0	2	17	430	445	429	456	0.75
5	16	0.0029	0.16	12.1	0.3	3	23	489	509	487	509	0.96
6	16	0.019	1.1	9.5	1.3	1	23	517	540	517	540	0.95
7	16	0.00025	0.014	15.4	2.0	2	23	545	566	544	566	0.97
8	16	0.00027	0.015	15.3	0.4	1	22	614	635	614	638	0.91
9	16	0.013	0.75	10.0	1.3	1	23	683	708	683	708	0.96
10	16	0.011	0.6	10.3	1.4	2	23	724	746	723	746	0.93
11	16	0.0038	0.21	11.7	0.2	3	23	753	774	751	774	0.92
12	16	0.025	1.4	9.1	0.5	2	23	778	800	777	800	0.96
13	16	7.1e-05	0.004	17.1	1.5	1	23	806	829	806	829	0.96
14	16	0.027	1.5	9.0	0.5	1	23	833	856	833	856	0.93
15	16	1.2e-05	0.00069	19.5	1.6	1	23	862	885	862	885	0.97
16	16	0.00011	0.0063	16.5	0.2	5	23	898	917	890	917	0.89

Sequence Information

Coding Sequence: atgtcggagaatttgaaaacaaataacgAATCTGAGCCTAGCTGCCTGCATTGCAGAGTGCACAACTCAAAGCAGCCGTTTCAGGAGATATTCGATGAACTGGGAATTGAAATCGAGCTGCCCGAGCTGCTGGCTAAATATTTTCAGATAAATATCAAACCCGATccgcaaaaacaacaactgctaTGCGAGGAGTGTGTCAAAACATTAATTCGCTTCTTCGACATTGATGAGCTGCAGCGGGAACAGGATGCAGCGGCCAAGGATAAGTCCAAGAAGCAGATCAAGAATGAGACAACGCCGTCAGCTGCTATCAAAAAGggcacaaaattaattaaaaaacaaacacctCCAGcgattaaagttaataatgaACCCAAAAAGTTGACAACTTCTGTAAAGTTGCcgacaccagcagcagcagctcctgcAGCAAGAGTTGCTACTGCCGCAGAGCCAGTTTCCATACGGATCACTAGAGCAAAAGCTGTGACAGTGACTCCGAAACGTAATCTGTCCAAACCAAAGACGGAAGGTAAACGGCACAGCGCCAAGGAAGCAGGAACAGGGGAGCAGGAGCAGATTAGCGAACTCTTACGTGACATACTGGATGATGAGAAGACGCCACCCGATGACAAATGCAATGTGGCAGTGACAAAAGGCGCGGCAGATGAGAAACAGTTGCAACAGGTTGCTGTCCAGGAAGAGGAGCAGGAAGATCAGGAAGAGCAACAGGACAAGCAGCGGGAAAATGCCGAGGAGCTGGAGTTTTTGCTCGAGCCAGAAGATGGTTCCTCTGACCTGGATGTGCGTCAATTCAAGTTGGAGAAGAACACATCAGTTGACTCACAGTCGCTAAGCGAGGATGAATCCATGAAAGTGGAGCCCTTCAACTTTGTTTTAATCAAGGAGTCTGATGGCATTGAAGATCTGTACGAATATCTAACCACTGTGGTGAAGACTTGCTTTGAGACCTTGACCTTTGAATGGGCCACCGTCTGTTGTCACTGCTCGCTGAAGTGCAGCAAATTCGAGAGCTTGTTGGCACACATGCAAAAGTGCCATCAGCTGCCAGAGGAGCACTACAAGTGCCCCATTGAGGAGTGCAACGCGGAGTTGCCAAATCGAAAATTCTTGGCCATGCATTTAGTTTTGCTGCATGCCCCTGTGGCAGACATACCCATTTATGGCAGCTGCCCGGAGTGCAACATGACCTTCTCCAATATATTGCAGTACAATAAACACTCCTGCGCCCATGTCATCAAGAAACGTCGTGGCGCCCGCTTGTATTGCGAAATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGCTTTAACTTTCACAATCAATTCCATTTGGAGAGACATAGGCCACGTGCCTGCTTTGTTTGCAGTTATGCGGACAACAACATCGATGAACTCTTCCAGCATTTGCATTATTCACACGAGCCCGAAGGCACGCTCTTCTGTGATATctGTGATCGCTATTTTCGAGATCCTGCTGTGTTTACGGATCACAATAAAACCCATGCGAATGTCGGCGGCGCCACACATTACTGCAGCAGTTGTAGCGCCACCTTTGAGACACGCGGACGTCTAAGTAGTCACATACGTGCAATGCACGGATCCATCATTAGCTGTGAGCTGTGCAGTCGAGAGTTTGCCTCGGAGTCCAACTACCACACGCACATGAAGAAGCATCTGATCATTGAGCGTGAAGTGCATGTGTGCAGCAATTGTGGCATCCTCAACGAGAGTCAGGAGAAGATGATGTCTCACGTGGAGAATGCTGATACGGTTTGTTTTGGCGTTGAAATCTATGTGGAACTTTTAAGGGATGCCTATGTCTGCGAATATTGTTCAGCATATTTTAAGCAGAAAACTGATTTGCGTGCTCATCGTGAATCTGGCATACATAAGGATGGTTTCTGCTGGTGTCAGCCGTGTGGCAAGGAGTTTCATGACATGAAAATATATCGTCATCATTTGCGCAACTTGCAGCAACAATTATCGGATGTTGAGCATCGCAAGCTGGAGATTTGCGTGCACTATATGTGCGATTATCAGGATTGTTTTGAGTCGTACATCAATTGGAATTCTTTGTACACTCACAAGAAACGGAATCACAATGTGGCCGATACGCAAGTGTTGGCGGAAAAGGTTAACGAATGGATCTGTCAGTTCTGTCAGAAGGTTTGTCGCTCCAAGATGTCGCTATCGGTGCATGTGGCACGCAGTCACAACAACAATAATGTGATTTGTCCAATCTGCAAGGCTTCGTATAAAGATGATGAGGCGTTGAAGAAGCATCACGCCTATTGGCATGAGCCTATGAAGTGTGCATTGTGCCTGAAAATGGTCAAGAATCGTCGCAACTATGACACACACATGAATGTGGTGCACTCGAATAATAAGCGTTATAACTGCGATGTCTGCGATAAGGGATTCTATCACAGGAGCGAAATGGAGGCACACAAGCGACAGTTGCATTCACAATTGTATAGCTGCGCACAGTGCAGCTTTAGTACGAGGAACAAGAATTCATTGTCGGTTCATGTTCTTGGTCAGCACTATAAGAGATTCGCCTTTGAGTGTAAGACTTGCAACAAGAACTTTGGACGTCGTCAGGGTTTAACCAATCATATGCAACGTGTCCATGGCTCCAAGAATATGTGTAGTGATTACTTCGAAGGCGGTTGCAACAAAACATTTAGCACAATCTCACAGTTAAACGTGCATGTGCGTAAAGCACATGATAACGGCATTGAGCTAGCCGATCTCGTGGAAGACTACCAGGAGGATCACGAAGAGCAGCTGGACGACGAGGATCAGCAGGATCACGAGGAGCAGGAGGTATACGAGGTGCAGGAACAGACgcaggagcaggaacagcagcaggaacGAAAATCGAAGCGTAAGAgttcaacagcagcatcaacatctAAGAAACGCTGCATCCGCATCATTGATGATACACAAATCGAGTTCATGAGCGCCGATGAGGATAACGTGAGCATTATGGACGCGGAAAACCTTGACAAAGAAACCAAATTCAAACCAACTCCGctgcATCAAGAGACAATTGATGTATAG
Protein Sequence: MSENLKTNNESEPSCLHCRVHNSKQPFQEIFDELGIEIELPELLAKYFQINIKPDPQKQQLLCEECVKTLIRFFDIDELQREQDAAAKDKSKKQIKNETTPSAAIKKGTKLIKKQTPPAIKVNNEPKKLTTSVKLPTPAAAAPAARVATAAEPVSIRITRAKAVTVTPKRNLSKPKTEGKRHSAKEAGTGEQEQISELLRDILDDEKTPPDDKCNVAVTKGAADEKQLQQVAVQEEEQEDQEEQQDKQRENAEELEFLLEPEDGSSDLDVRQFKLEKNTSVDSQSLSEDESMKVEPFNFVLIKESDGIEDLYEYLTTVVKTCFETLTFEWATVCCHCSLKCSKFESLLAHMQKCHQLPEEHYKCPIEECNAELPNRKFLAMHLVLLHAPVADIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGARLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADNNIDELFQHLHYSHEPEGTLFCDICDRYFRDPAVFTDHNKTHANVGGATHYCSSCSATFETRGRLSSHIRAMHGSIISCELCSREFASESNYHTHMKKHLIIEREVHVCSNCGILNESQEKMMSHVENADTVCFGVEIYVELLRDAYVCEYCSAYFKQKTDLRAHRESGIHKDGFCWCQPCGKEFHDMKIYRHHLRNLQQQLSDVEHRKLEICVHYMCDYQDCFESYINWNSLYTHKKRNHNVADTQVLAEKVNEWICQFCQKVCRSKMSLSVHVARSHNNNNVICPICKASYKDDEALKKHHAYWHEPMKCALCLKMVKNRRNYDTHMNVVHSNNKRYNCDVCDKGFYHRSEMEAHKRQLHSQLYSCAQCSFSTRNKNSLSVHVLGQHYKRFAFECKTCNKNFGRRQGLTNHMQRVHGSKNMCSDYFEGGCNKTFSTISQLNVHVRKAHDNGIELADLVEDYQEDHEEQLDDEDQQDHEEQEVYEVQEQTQEQEQQQERKSKRKSSTAASTSKKRCIRIIDDTQIEFMSADEDNVSIMDAENLDKETKFKPTPLHQETIDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507108; iTF_00575815; iTF_00529020;
90% Identity: -
80% Identity: -